Differences in competitive ability among races of Colletotrichum graminicola in mixtures

Mixtures of races of Colletotrichum graminicola, causing sorghum (Sorghum bicolor) anthracnose and differing in their virulence range, were inoculated for five and six generations on the susceptible sorghum cultivar BR009 (Tx623), in two experiments in a greenhouse. In each generation a sample of 50 single spore isolates was obtained and inoculated on a standard differential set to determine the proportion of each race in the mixture. Isolates of the race 30A, with the narrowest virulence range, predominated over isolates of the more complex races 31B, 31C and 31E indicating the existence of differences in the survival ability among races of this pathogen.

Cultural differences in web-based health information seeking of Finnish and Japanese students

Abstrakti

Application of Computational Fluid Dynamics in Modeling Blood Flow in Human Thoracic Aorta

The aim of this study was to simulate blood flow in thoracic human aorta and understand the role of flow dynamics in the initialization and localization of atherosclerotic plaque in human thoracic aorta. The blood flow dynamics in idealized and realistic models of human thoracic aorta were numerically simulated in three idealized and two realistic thoracic aorta models. The idealized models of thoracic aorta were reconstructed with measurements available from literature, and the realistic models of thoracic aorta were constructed by image processing Computed Tomographic (CT) images. The CT images were made available by South Karelia Central Hospital in Lappeenranta. The reconstruction of thoracic aorta consisted of operations, such as contrast adjustment, image segmentations, and 3D surface rendering. Additional design operations were performed to make the aorta model compatible for the numerical method based computer code. The image processing and design operations were performed with specialized medical image processing software. Pulsatile pressure and velocity boundary conditions were deployed as inlet boundary conditions. The blood flow was assumed homogeneous and incompressible. The blood was assumed to be a Newtonian fluid. The simulations with idealized models of thoracic aorta were carried out with Finite Element Method based computer code, while the simulations with realistic models of thoracic aorta were carried out with Finite Volume Method based computer code. Simulations were carried out for four cardiac cycles. The distribution of flow, pressure and Wall Shear Stress (WSS) observed during the fourth cardiac cycle were extensively analyzed. The aim of carrying out the simulations with idealized model was to get an estimate of flow dynamics in a realistic aorta model. The motive behind the choice of three aorta models with distinct features was to understand the dependence of flow dynamics on aorta anatomy. Highly disturbed and nonuniform distribution of velocity and WSS was observed in aortic arch, near brachiocephalic, left common artery, and left subclavian artery. On the other hand, the WSS profiles at the roots of branches show significant differences with geometry variation of aorta and branches. The comparison of instantaneous WSS profiles revealed that the model with straight branching arteries had relatively lower WSS compared to that in the aorta model with curved branches. In addition to this, significant differences were observed in the spatial and temporal profiles of WSS, flow, and pressure. The study with idealized model was extended to study blood flow in thoracic aorta under the effects of hypertension and hypotension. One of the idealized aorta models was modified along with the boundary conditions to mimic the thoracic aorta under the effects of hypertension and hypotension. The results of simulations with realistic models extracted from CT scans demonstrated more realistic flow dynamics than that in the idealized models. During systole, the velocity in ascending aorta was skewed towards the outer wall of aortic arch. The flow develops secondary flow patterns as it moves downstream towards aortic arch. Unlike idealized models, the distribution of flow was nonplanar and heavily guided by the artery anatomy. Flow cavitation was observed in the aorta model which was imaged giving longer branches. This could not be properly observed in the model with imaging containing a shorter length for aortic branches. The flow circulation was also observed in the inner wall of the aortic arch. However, during the diastole, the flow profiles were almost flat and regular due the acceleration of flow at the inlet. The flow profiles were weakly turbulent during the flow reversal. The complex flow patterns caused a non-uniform distribution of WSS. High WSS was distributed at the junction of branches and aortic arch. Low WSS was distributed at the proximal part of the junction, while intermedium WSS was distributed in the distal part of the junction. The pulsatile nature of the inflow caused oscillating WSS at the branch entry region and inner curvature of aortic arch. Based on the WSS distribution in the realistic model, one of the aorta models was altered to induce artificial atherosclerotic plaque at the branch entry region and inner curvature of aortic arch. Atherosclerotic plaque causing 50% blockage of lumen was introduced in brachiocephalic artery, common carotid artery, left subclavian artery, and aortic arch. The aim of this part of the study was first to study the effect of stenosis on flow and WSS distribution, understand the effect of shape of atherosclerotic plaque on flow and WSS distribution, and finally to investigate the effect of lumen blockage severity on flow and WSS distributions. The results revealed that the distribution of WSS is significantly affected by plaque with mere 50% stenosis. The asymmetric shape of stenosis causes higher WSS in branching arteries than in the cases with symmetric plaque. The flow dynamics within thoracic aorta models has been extensively studied and reported here. The effects of pressure and arterial anatomy on the flow dynamic were investigated. The distribution of complex flow and WSS is correlated with the localization of atherosclerosis. With the available results we can conclude that the thoracic aorta, with complex anatomy is the most vulnerable artery for the localization and development of atherosclerosis. The flow dynamics and arterial anatomy play a role in the localization of atherosclerosis. The patient specific image based models can be used to diagnose the locations in the aorta vulnerable to the development of arterial diseases such as atherosclerosis.

Pienahitsin sijainnin vaikutus kuormaa kantamattoman T-liitoksen väsymiskestävyyteen

Hitsatuissa rakenteissa on paljon hitsien aiheuttamia epäjatkuvuuskohtia, jotka ovat alttiita vaurioitumaan väsyttävän kuormituksen alaisina. Standardit ja normit auttavat suunnittelua rakenneyksityiskohtien analysoinnissa, mutta ohjeiden arvot vaihtelevat paljon. Onkin tär-keää päättää, mitä standardia tai normia käytetään ja saada tutkimustuloksia tukemaan ohjeen käyttöä. Tämä työ on tehty Konecranes Finland Oy:lle. Työn tarkoituksena on etsiä käytössä olevi-en ohjeiden joukosta suunnittelun kannalta parhaiten todellista rakennetta kuvaava. Työssä esitellään käytössä olevia standardeja ja normeja sekä vertaillaan niiden välisiä eroja rakenneyksityiskohdan väsymiskestävyyden määrittämisessä. Työssä tarkastellaan myös hitsatun rakenteen väsymiseen vaikuttavia tekijöitä sekä väsymisanalyysissä käytet-täviä menetelmiä. Tutkittavaan liitokseen valittiin kolme erilaista hitsiä, yksi –ja kaksipuolinen pienahitsi sekä katkopienahitsi. Elementtimenetelmän avulla luotiin malleja koekappaleista ja laskettiin niille väsymiskestävyydet. Tämä lisäksi väsymistä tarkasteltiin väsytyskokeilla, jotka suoritti Lappeenrannan Teknillisen Yliopiston Teräsrakenteiden laboratorio. Lopputuloksena työstä saatiin tietoa hitsien väsymiskestävyyksistä. Liitosten väsymiskes-tävyydet olivat hyviä ja varsinkin katkopienahitsin tulokset olivat odotettua paremmat. Kat-kopienahitsin väsymiskestävyys vaatii tämän työn tulosten perusteella lisää tutkimista.

Flexible multibody approach in bone strain estimation during physical activity:

Bone strain plays a major role as the activation signal for the bone (re)modeling process, which is vital for keeping bones healthy. Maintaining high bone mineral density reduces the chances of fracture in the event of an accident. Numerous studies have shown that bones can be strengthened with physical exercise. Several hypotheses have asserted that a stronger osteogenic (bone producing) effect results from dynamic exercise than from static exercise. These previous studies are based on short-term empirical research, which provide the motivation for justifying the experimental results with a solid mathematical background. The computer simulation techniques utilized in this work allow for non-invasive bone strain estimation during physical activity at any bone site within the human skeleton. All models presented in the study are threedimensional and actuated by muscle models to replicate the real conditions accurately. The objective of this work is to determine and present loading-induced bone strain values resulting from physical activity. It includes a comparison of strain resulting from four different gym exercises (knee flexion, knee extension, leg press, and squat) and walking, with the results reported for walking and jogging obtained from in-vivo measurements described in the literature. The objective is realized primarily by carrying out flexible multibody dynamics computer simulations. The dissertation combines the knowledge of finite element analysis and multibody simulations with experimental data and information available from medical field literature. Measured subject-specific motion data was coupled with forward dynamics simulation to provide natural skeletal movement. Bone geometries were defined using a reverse engineering approach based on medical imaging techniques. Both computed tomography and magnetic resonance imaging were utilized to explore modeling differences. The predicted tibia bone strains during walking show good agreement with invivo studies found in the literature. Strain measurements were not available for gym exercises; therefore, the strain results could not be validated. However, the values seem reasonable when compared to available walking and running invivo strain measurements. The results can be used for exercise equipment design aimed at strengthening the bones as well as the muscles during workout. Clinical applications in post fracture recovery exercising programs could also be the target. In addition, the methodology introduced in this study, can be applied to investigate the effect of weightlessness on astronauts, who often suffer bone loss after long time spent in the outer space.

Fatigue study of the fillet weld waving on weld toe and the penetration in the weld root based on the effective notch stress approach

The fatigue failure of structures under fluctuating loads in fillet weld joints raises a demand to determine the parameters related to this type of loading. In this study, the stress distribution in the susceptible area of weld toe and weld root in fillet welded models analyzed by finite element method applying FEMAP software. To avoid the geometrical singularity on the path of analytical stress analysis in the toe and root area of a weld model the effective notch stress approach applied by which a proper fictitious rounding that mostly depend on the material of structure is applied. The models with different weld toe waving width and radius are analyzed while the flank angle of weld varied in 45 and 30 degrees. The processed results shows that the waving compare to the straight weld toe makes differences in the value of stress and consequently the stress concentration factor between the tip and depth of the waves in the weld toe which helps to protect the crack of propagation and gives enough time and tools to be informed of the crack initiation in the structure during the periodical observation of structure. In the weld root study the analyses among the models with the welding penetration percentage from non-penetration to the full-penetration shows a slightly increase in the root area stress value which comparing with the stiffening effect of penetration conclude that the half-penetration can make an optimization between the stress increase and stiffening effect of deep penetration.

Eri laskentamenetelmien vertailu hitsatun rakenteen väsymislaskennassa

Tässä työssä tutkittiin eri mitoitusmenetelmien soveltuvuutta hitsattujen rakenteiden vä-symislaskennassa. Käytetyt menetelmät olivat rakenteellinen jännityksen menetelmä, te-hollisen lovijännityksen menetelmä ja murtumismekaniikka. Lisäksi rakenteellisen jänni-tyksen määrittämiseksi käytettiin kolmea eri menetelmää. Menetelmät olivat pintaa pitkin ekstrapolointi, paksuuden yli linearisointi ja Dongin menetelmä. Väsymiskestävyys määritettiin kahdelle hitsiliitoksen yksityiskohdalle. Laskenta tehtiin käyttäen elementtimenetelmää rakenteen 3D-mallille. Tutkittavasta aggregaattirungosta oli olemassa FE-malli mutta alimallinnustekniikkaa hyödyntämällä pystyttiin yksityiskohtai-semmin tutkimaan vain pientä osaa koko rungon mallista. Rakenteellisen jännityksen menetelmä perustuu nimellisiin jännityksiin. Kyseinen mene-telmä ei vaadi geometrian muokkausta. Yleensä rakenteellisen jännityksen menetelmää käytetään hitsin rajaviivan väsymislaskennassa, mutta joissain tapauksissa sitä on käytetty juuren puolen laskennassa. Tässä työssä rakenteellisen jännityksen menetelmää käytettiin myös juuren puolen tutkimisessa. Tehollista lovijännitystä tutkitaan mallintamalla 1 mm fiktiiviset pyöristykset sekä rajaviivalle että juuren puolelle. Murtumismekaniikan so-veltuvuutta tutkittiin käyttämällä Franc2D särön kasvun simulointiohjelmaa. Väsymislaskennan tulokset eivät merkittävästi poikkea eri laskentamenetelmien välillä. Ainoastaan rakenteellisen jännityksen Dongin menetelmällä saadaan poikkeavia tuloksia. Tämä johtuu pääasiassa siitä, että menetelmän laskentaetäisyydestä ei ole tietoa. Raken-teellisen jännityksen menetelmällä, tehollisen lovijännityksen menetelmällä ja murtumis-mekaniikalla saadaan samansuuntaiset tulokset. Suurin ero menetelmien välillä on mal-linnuksen ja laskennan vaatima työmäärä.

Liikkuvan kivimurskaimen syötinosan rakenneanalyysi osarakennetekniikan avulla

Työn tarkoituksena oli selvittää, miten osarakennetekniikkaa voidaan soveltaa siirrettävän kivimurskaimen syötinosan simuloinnissa. Tätä tutkittiin luomalla kahdella eri ohjelmistolla simulaatiomalli syötinosasta ja mallintamalla syötinosan runko joustavaksi kappaleeksi osarakennetekniikan avulla. Luotujen simulointimallien tarkkuutta selvitettiin vertaamalla niistä saatuja rungon jännityksiä tutkittavan rakenteen rungosta mitattuihin jännityksiin. Työn tarkoituksena oli myös tutkia, miten hyvin simulaatiomallit soveltuvat käytettäväksi syötinosan tuotekehityksessä. Tässä työssä käytettiin syötinosan simulaatiomallin luomiseen ANSYS-ohjelmistoa ja ADAMS-ohjelmistoa. Simulaatiomalleihin lisättiin tutkittavasta järjestelmästä mitattu ohjaussignaali sekä syötinosan jousien arvot. Järjestelmän rakenneominaisuudet saatiin suoraan valmistajan luovuttamista tiedoista. ADAMS-ohjelmistolla mallinnetussa simulaatiomallissa runko mallinnettiin joustavaksi ANSYS-ohjelmistossa, josta se siirrettiin ADAMS-ohjelmistoon. Saaduista tuloksista kävi ilmi, että osarakennetekniikkaa voidaan hyödyntää syötinosan joustavan rungon simuloinnissa. Tutkittavasta järjestelmästä mitatuissa jännityksissä ja simulaatiomalleista saaduissa jännityksissä oli eroja, mutta jännityshistorian muodot ja suuruusluokat vastasivat pääosin toisiaan. Tulosten parantamiseksi tulee selvittää lisää alkuarvoja tutkittavasta järjestelmästä ja varmistua nyt saatujen jousiparametrien oikeellisuudesta.

Geometric nonlinear dynamic analysis of plates and shells using eight-node hexahedral finite elements with reduced integration

This work presents a geometric nonlinear dynamic analysis of plates and shells using eight-node hexahedral isoparametric elements. The main features of the present formulation are: (a) the element matrices are obtained using reduced integrations with hourglass control; (b) an explicit Taylor-Galerkin scheme is used to carry out the dynamic analysis, solving the corresponding equations of motion in terms of velocity components; (c) the Truesdell stress rate tensor is used; (d) the vector processor facilities existing in modern supercomputers were used. The results obtained are comparable with previous solutions in terms of accuracy and computational performance.

Application of the finite element method in cold forging processes

The demand for more efficient manufacturing processes has been increasing in the last few years. The cold forging process is presented as a possible solution, because it allows the production of parts with a good surface finish and with good mechanical properties. Nevertheless, the cold forming sequence design is very empirical and it is based on the designer experience. The computational modeling of each forming process stage by the finite element method can make the sequence design faster and more efficient, decreasing the use of conventional "trial and error" methods. In this study, the application of a commercial general finite element software - ANSYS - has been applied to model a forming operation. Models have been developed to simulate the ring compression test and to simulate a basic forming operation (upsetting) that is applied in most of the cold forging parts sequences. The simulated upsetting operation is one stage of the automotive starter parts manufacturing process. Experiments have been done to obtain the stress-strain material curve, the material flow during the simulated stage, and the required forming force. These experiments provided results used as numerical model input data and as validation of model results. The comparison between experiments and numerical results confirms the developed methodology potential on die filling prediction.

An alternative finite element formulation for determination of streamlines in two-dimensional problems

It is well known that the numerical solutions of incompressible viscous flows are of great importance in Fluid Dynamics. The graphics output capabilities of their computational codes have revolutionized the communication of ideas to the non-specialist public. In general those codes include, in their hydrodynamic features, the visualization of flow streamlines - essentially a form of contour plot showing the line patterns of the flow - and the magnitudes and orientations of their velocity vectors. However, the standard finite element formulation to compute streamlines suffers from the disadvantage of requiring the determination of boundary integrals, leading to cumbersome implementations at the construction of the finite element code. In this article, we introduce an efficient way - via an alternative variational formulation - to determine the streamlines for fluid flows, which does not need the computation of contour integrals. In order to illustrate the good performance of the alternative formulation proposed, we capture the streamlines of three viscous models: Stokes, Navier-Stokes and Viscoelastic flows.

Transfer pricing documentation differences in Finland and China - Case company study

This Master’s Thesis deals with the topic of transfer pricing documentation in Finland and China. The goal of the research is to find what kind of differences exist in a single case company’s transfer pricing documentation when following Chinese or Finnish transfer pricing regulations. The study is carried out as a case study research. The theoretical framework consists of information from different transfer pricing topics and transfer pricing documentation regulations in China and Finland. The main research material was the case company’s transfer pricing documents with the support of open discus-sion with one of the case company’s employees. The study compared the 2009 and 2010 documents. The 2009 document was done based on the Finnish method while the 2010 document was based on the Chinese documentation principles. The conclusion made is that the content of the documents was heavily similar, while the main differences come in the way the content is presented and the level of detail used in the documents.

Mechanical design and analysis of modular active magnetic bearing test rig

Tässä työssä on tutkittu modulaarisen aktiivimagneettilaakeroidun koelaitteen mekaanista suunnittelua ja analysointia. Suurnopeusroottorin suunnittelun teoria on esitelty. Lisäksi monia analyyttisiä mallinnusmenetelmiä mekaanisten kuormitusten mallintamiseksi on esitelty. Koska kyseessä on suurnopeussähkökone, roottoridynamiikka ja sen soveltuvuus suunnittelussa on esitelty. Magneettilaakerien rakenteeseen ja toimintaan on tutustuttu osana tätä työtä. Kirjallisuuskatsaus nykyisistä koelaitteista esimerkiksi komponenttien ominaisuuksien tunnistamiseen ja roottoridynamiikan tutkimuksiin on esitelty. Työn rajauksena on konseptisuunnittelu muunneltavalle magneettilaakeroidulle (AMB) koelaitteelle ja suunnitteluprosessin dokumentointi. Muunneltavuuteen päädyttiin, koska se mahdollistaa erilaisten komponenttiasetteluiden testaamisen erilaisille magneettilaakerikokoonpanoille ja roottoreille. Pääpaino tässä työssä on suurnopeus induktiokoneen roottorin suunnittelussa ja mallintamisessa. Modulaaristen toimilaitteiden kuten magneettilaakerien ja induktiosähkömoottorin rakenne on esitelty ja modulaarisen rakenteen käytettävyyden hyödyistä koelaitekäytössä on dokumentoitu. Analyyttisiä ja elementtimenetelmään perustuvia tutkimusmenetelmiä on käytetty tutkittaessa suunniteltua suurnopeusroottoria. Suunnittelun ja analysoinnin tulokset on esitelty ja verrattu keskenään eri mallinnusmenetelmien välillä. Lisäksi johtopäätökset sähkömagneettisten osien liittämisen monimutkaisuudesta ja vaatimuksista roottoriin ja toimilaitteisiin sekä mekaanisten että sähkömagneettisten ominaisuuksien optimoimiseksi on dokumentoitu.