928 resultados para compromise
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Pós-graduação em Ciências Odontológicas - FOAR
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Pós-graduação em Odontologia - FOAR
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Pós-graduação em Química - IQ
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Pós-graduação em Engenharia de Produção - FEB
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Background: Chronic kidney disease (CKD) is one of the most serious public health problems. The increasing prevalence of CKD in developed and developing countries has led to a global epidemic. The hypothesis proposed is that patients undergoing dialysis would experience a marked negative influence on physiological variables of sleep and autonomic nervous system activity, compromising quality of life.Methods/Design: A prospective, consecutive, double blind, randomized controlled clinical trial is proposed to address the effect of dialysis on sleep, pulmonary function, respiratory mechanics, upper airway collapsibility, autonomic nervous activity, depression, anxiety, stress and quality of life in patients with CKD. The measurement protocol will include body weight (kg); height (cm); body mass index calculated as weight/height(2); circumferences (cm) of the neck, waist, and hip; heart and respiratory rates; blood pressures; Mallampati index; tonsil index; heart rate variability; maximum ventilatory pressures; negative expiratory pressure test, and polysomnography (sleep study), as well as the administration of specific questionnaires addressing sleep apnea, excessive daytime sleepiness, depression, anxiety, stress, and quality of life.Discussion: CKD is a major public health problem worldwide, and its incidence has increased in part by the increased life expectancy and increasing number of cases of diabetes mellitus and hypertension. Sleep disorders are common in patients with renal insufficiency. Our hypothesis is that the weather weight gain due to volume overload observed during interdialytic period will influence the degree of collapsibility of the upper airway due to narrowing and predispose to upper airway occlusion during sleep, and to investigate the negative influences of haemodialysis in the physiological variables of sleep, and autonomic nervous system, and respiratory mechanics and thereby compromise the quality of life of patients.
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In vitro-produced bovine embryos become infected after exposure to bovine Herpesvirus type 5 (BoHV-5), yet no changes in developmental rates, mitochondrial activity and inhibition of apoptosis are detected in comparison to unexposed embryos. Thus, the aim of the present study was to assess the transcription of mitochondria-mediated apoptosis genes using TaqMan real-time polymerase chain reaction. Transcripts of mcl-1, caspase-2, -3, Apaf-1 and Bax genes were measured after exposure to BoHV-5 in vitro. Mitochondrial dehydrogenase activity was evaluated by MIT test and compared between groups of exposed and unexposed embryos, at day 7 of development. The rate of oocyte maturation was assessed by the extrusion of the first polar body. In summary, BoHV-5 exposed embryos retained their viability, mitochondrial dehydrogenase activity and displayed up-regulation of transcription of survival mcl-1 gene and down-regulation of Bax transcription in relation to mitochondria-mediated pathway which might improve embryo viability. These findings demonstrate that BoHV-5 exposed embryos maintain their viability and mitochondrial dehydrogenase activity with no compromise of embryos produced in vitro. (c) 2013 Elsevier Ltd. All rights reserved.
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Objective: To compare dental plaster model (DPM) and cone-beam computed tomography (CBCT) in the measurement of the dental arches, and investigate whether CBCT image artifacts compromise the reliability of such measurements.Materials and Methods: Twenty patients were divided into two groups based on the presence or absence of metallic restorations in the posterior teeth. Both dental arches of the patients were scanned with the CBCT unit i-CAT, and DPMs were obtained. Two examiners obtained eight arch measurements on the CBCT images and DPMs and repeated this procedure 15 days later. The arch measurements of each patient group were compared separately by the Wilcoxon rank sum (Mann-Whitney U) test, with a significance level of 5% (alpha = .05). Intraclass correlation measured the level of intraobserver agreement.Results: Patients with healthy teeth showed no significant difference between all DPM and CBCT arch measurements (P > .05). Patients with metallic restoration showed significant difference between DPM and CBCT for the majority of the arch measurements (P > .05). The two examiners showed excellent intraobserver agreement for both measuring methods with intraclass correlation coefficient higher than 0.95.Conclusion: CBCT provided the same accuracy as DPM in the measurement of the dental arches, and was negatively influenced by the presence of image artifacts.
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The tillage comprises on average 25% of the cost of deploying a reed, so this cost reduction measures are desirable since they do not compromise the quality of the operation and longevity of sugarcane. The objective was to evaluate the effect of different tillage systems in Acrustox, correlating soil physical properties and characteristics of sugarcane agroindustrial plant cane and ratoon cane. We used five types of soil tillage, over experimental design in blocks with five replications. The particle size was measured every 0.1 m to 0.4 m depth, through deformed soil samples collected at the end of the first growth cycle of the culture. For other soil physical properties: bulk density, total porosity and water content, assessments were performed at the end of each cycle, collecting soil samples in layers of 0-0.20 to 0.21-0.40 m, in addition to performing the penetration resistance, using a penetrometer impact. The response of sugarcane depending on the types of tillage was determined from the evaluation of productivity per hectare of stem (TCH), sugar (TPH), the values of pol % cane (AP), sugar total recoverable (ATR) and fiber samples collected at harvest stalk of sugarcane plant and ratoon cane. In the tillage studied, there was a change of the physical attributes of the soil, causing reduced productivity in 2009/2010 crop, compared with the 2008/2009 season. In tillage system of furrowing direct lowest result was observed for TCH, especially in 2009/2010 crop, when the difference with conventional tillage was 20.53 Mg ha(-1).
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Pós-graduação em Agronomia (Energia na Agricultura) - FCA
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Pós-graduação em Anestesiologia - FMB
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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In a previous research, it was observed that are symbolic exchanges established between the persons and the environment they live in that allow them to interact with others, leading them to reorganize their internal cognitive structures, reaching more elaborated stages. In the case of a person with deafness, the possibility of exchange can be compromised and knowledge about the construction of the temporal notion seems to be essential to enable a path of explanation about the difficulties they have regarding their cognitive development. Thus, based on the theory of Jean Piaget, the study intended to understand how the temporal notion constitutes as possible subject to the process of building the real, and examine, through empirical evaluation, if the difficulty in establishing symbolic exchanges caused by deafness would compromise the development of this notion. For this purpose, bibliographical research and empirical research were made, by the comparative evaluating between the performance of deaf and hearing subjects in relation to the construction of temporal notion. Two groups of subjects aged between 10 and 12 years were composed: one with three deaf subjects and another with 3 listeners. The assessment and analysis of the data were based on an experiment created by Piaget and his staff. The results showed that the listeners present responses from operative level, compatible with the age range in which they found themselves. In contrast, the deaf subjects showed responses of transition level, which indicates a situation of cognitive delay. We conclude that the potential compromise linguistic presented by deaf people, can hinder the activity representative causing delay in construction of temporal notion and consequently the development of thought. We conclude that the possible linguistic committal presented by deaf people can hinder the representative activity, causing delay in construction of temporal notion and consequently in the development of thought. In this sense, it seems that the Sign Language constitutes an important tool for deaf people because it allows symbolic exchanges that favor the cognitive development.
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Pós-graduação em Agronomia (Entomologia Agrícola) - FCAV
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Pós-graduação em Química - IQ