Français 355

Contient : 1° « L'Ystoire de Meliadus et de Gyron le Courtois et du chevalier sans paour », de « RUSTICIEN, de Pise » ; 2° « Le Livre de Meliadus et de Guiron le Courtois et de Palamedes », du même, contenant en partie le roman de Guiron le Courtois d' « HELIE DE BORRON », dont le prologue est conservé

Français 355

Contient : 1° « L'Ystoire de Meliadus et de Gyron le Courtois et du chevalier sans paour », de « RUSTICIEN, de Pise » ; 2° « Le Livre de Meliadus et de Guiron le Courtois et de Palamedes », du même, contenant en partie le roman de Guiron le Courtois d' « HELIE DE BORRON », dont le prologue est conservé

Un Français : le colonel Denfert-Rochereau (Nouvelle édition) / par Auguste Marais,...

Collection : Bibliothèque de la jeunesse française

Nouvelles armes thérapeutiques contre le mélanome de stade IV [New therapeutic weapons in stage IV melanoma].

The treatment of stage IV melanoma has been revolutionized over the last years with the development of immunotherapies that, for the first time, have shown a significant benefit in overall survival, as well as with extremely effective targeted therapies, that also led to improved survival. These results are the fruits of an important translational research effort that allowed a rational approach with a very fast clinical development. The treatment of metastatic melanoma is, therefore, an illustration of the new paradigms of modern molecular research in oncology. In this review, we will present the various agents that have made the proof of their clinical benefit, as well as the scientific discoveries that allowed their development. Some of the remaining questions will be touched upon with the ongoing clinical trials. Inclusion of patients in these studies remains the top priority to improve on the clinical care.

Estratègies en la presa de decisió d’una jugadora i el seu entrenador en el rugbi femení d’alt nivell = Estrategias en la toma de decisión de una jugadora y su entrenador en el rugby femenino de alto nivel

This research compared knowledge representation of a female rugby player and her coach concerning decision-making of the fly half in attack from second phase play. The current female England fly half and the England Women’s Rugby head coach analysed, from the fly half perspective, 15 sequences of the England v Spain match played during the 2002 Women’s Rugby World Cup in Barcelona. Protocol analysis of subjects’ verbal reports revealed that the player generated more overall concepts than the coach. The player’s analysis was based on condition-action statements related to goals. In contrast, the knowledge representation of the coach centred on conditions related to actions. Both subjects generated regulatory and do concepts in a similar way, with a majority of positive feedbacks. Knowledge structure of the player appeared to be more complex, but sophistication of concepts was similar for both subjects. Critical analysis of complete sequences viewed revealed a more severe self-assessment of the player compared with that of her coach. In conclusion, and despite the differences found between subjects, the player and her coach demonstrated possession of a similar pattern of decision-making strategies that could be due to a successful transmission of knowledge from the coach to his player