Strain rates estimated by geodetic observations in the Borborema Province, Brazil

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Ecology of the Skink, Mabuya arajara Reboucas-Spieker, 1981, in the Araripe Plateau, Northeastern Brazil

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

A new turtle from the Upper Cretaceous Bauru Group of Brazil, updated phylogeny and implications for age of the Santo Anastacio Formation

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

A new species of Rhinella (Anura: Bufonidae) from Northeastern Brazil

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Big, bad, and beautiful: phylogenetic relationships of the horned frogs (Anura: Ceratophryidae)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Does the rattle of Crotalus durissus terrificus reveal its dietary history?

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Skeletal muscle degeneration and regeneration after injection of bothropstoxin-II, a phospholipase A2 isolated from the venom of the snake Bothrops jararacussu

A myotoxic phospholipase A2, named bothropstoxin II (BthTX-II), was isolated from the venom of the South American snake Bothrops jararacussu and the pathogenesis of myonecrosis induced by this toxin was studied in mice. BthTX-II induced a rapid increase in plasma creatine kinase levels. Histological and ultrastructural observations demonstrate that this toxin affects muscle fibers by first disrupting the integrity of plasma membrane, as delta lesions were the earliest morphological alteration and since the plasma membrane was interrupted or absent in many portions. In agreement with this hypothesis, BthTX-II released peroxidase entrapped in negatively charged multilamellar liposomes and behaved as an amphiphilic protein in charge shift electrophoresis, an indication that its mechanism of action might be based on the interaction and disorganization of plasma membrane phospholipids. Membrane damage was followed by a complex series of morphological alterations in intracellular structures, most of which are probably related to an increase in cytosolic calcium levels. Myofilaments became hypercontracted into dense clumps which alternated with cellular spaces devoid of myofibrillar material. Later on, myofilaments changed to a hyaline appearance with a more uniform distribution. Mitochondria were drastically affected, showing high amplitude swelling, vesiculation of cristae, formation of flocculent densities, and membrane disruption. By 24 hr, abundant polymorphonuclear leucocytes and macrophages were observed in the interstitial space as well as inside necrotic fibers. Muscle regeneration proceeded normally, as abundant myotubes and regenerating myofibers were observed 7 days after BthTX-II injection. By 28 days regenerating fibers had a diameter similar to that of adult muscle fibers, although they presented two distinctive features: central location of nuclei and some fiber splitting. This good regenerative response may be explained by the observation that BthTX-II does not affect blood vessels, nerves, or basal laminae. © 1991.

Effects of laparoscopy on the cardiorespiratory system of brown brocket deer (Mazama gouazoubira) anesthetized with ketamine/ xylazine/ midazolam combination and isoflurane

A laparoscopia ainda é pouco utilizada como ferramenta para técnicas de reprodução assistida em cervídeos sul-americanos, não havendo informações sobre seus efeitos e protocolos anestésicos seguros para sua realização. Objetivaramse avaliar as possíveis alterações na freqüência cardíaca (FC), respiratória (FR), saturação de oxihemoglobina (SpO2) e temperatura retal (TR) durante a laparoscopia para visualização dos órgãos reprodutivos de seis fêmeas de veado-catingueiro (Mazama gouazoubira) anestesiadas com a associação cetamina (5mg/kg), xilazina (0,3mg/kg), midazolam (0,5mg/kg) e isofluorano. Cada animal, após anestesiado, foi posicionado em decúbito dorsal para realização de duas laparoscopias com insuflação abdominal de CO2 (14,2 ± 2,39mmHg; M ± EPM) com intervalo de 40 dias. Para avaliar os principais eventos da laparoscopia, esta foi dividida em três períodos: animal sem insuflação abdominal (P1), com insuflação abdominal (P2) e insuflação abdominal com os quadris elevados a 45º (P3). O controle foi realizado após 40 dias da última laparoscopia, para isto, cada animal foi novamente anestesiado e mantido em decúbito dorsal por um período de tempo igual ao tempo médio de duração das anestesias realizadas nas laparoscopias, sem que o procedimento laparoscópico fosse realizado. O tempo de anestesia dos controles foi também dividido em P1, P2 e P3, respeitando o tempo médio de duração de cada um destes períodos das laparoscopias. Para análise dos dados foi usado o teste de análise de variância (ANOVA) seguido do teste de Tukey e valores de P<0,05 considerados significativos. Não houve diferença significativa nos parâmetros estudados em nenhum dos períodos estabelecidos para o controle e laparoscopia. Porém, a FR média entre P1 (38,8 ± 4,42) e P3 (32,7 ± 4,81) e a TR média entre P1 (38,2ºC ± 0,17), P2 (37,6ºC ± 0,19) e P3 (37,0ºC ± 0,21) variaram significativamente, independente da laparoscopia. Tais dados permitiram concluir que a laparoscopia não promoveu alterações significativas nos parâmetros avaliados, embora o protocolo anestésico utilizado tenha contribuído para redução da temperatura retal resultando em risco de hipotermia durante a anestesia.

Repetitive DNA sequences and evolution of ZZ/ZW sex chromosomes in characidium (teleostei: characiformes)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Differences in physiological traits associated with water balance among rodents, and their relationship to tolerance of habitat fragmentation

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Aspectos Morfologicos e Histoquimicos de los Musculos Extraoculares del Zorrillo (Didelphis albiventris)

The extraocular muscle fibres of the South-American opossum were determined according to their metabolic profiles using NADH-diaforase, and myofibrilar ATPase after pre-incubation in both acid (pH 4.3) and alkaline (pH 10.4) media. Three muscles were selected to study the arrangement of the fibres (obliquous dorsalis, rectus dorsalis and rectus lateralis muscles). It was demonstrated that they are organized in two layers: the orbital layer composed by small diameter fibres and the global layer with three-times thicker fibres than the former. The global layer has three fibre types: white, red and intermediate; while the orbital layer presents two fibre types, which react differently to the ATPase.

Amazônia, UNASUL e desenvolvimento sustentável: o papel do Brasil (2003-2010)

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Evaluation of oral health in a community of native brazilians of the umutina reservation, Mato Grosso State

Fundação do Amparo à Pesquisa do Estado de São Paulo (FAPESP)

A segurança através do espelho convexo das Américas: percepções, imagens e interesses na conformação de uma identidade

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A política externa estadunidense no atual quadro político sul-americano

The central thesis that we aim to survey in this paper is that the present South-American political scene has required of the American imperialism a strategical redesign, in the sense of the neutralization, weakening and, if it is possible, destruction of regional political experiences/tendencies not aligned to its foreign politics. Under the mask of the defense of democracy and beneath the argument that Latin American "market oriented politics" are at stake, due to questions that goes back from the "delin-quency" —in Mexico—, the global terrorism, the organized international crime up to the worldwide drug traffic, the global strategy of American imperialism then sets up the definition of a new doctrine of preventive war that justifies the utilization of hard power against any country, in the name of its own defense. At the heart of the question what —actually— is in the agenda is the defense (and reproduction) of the benefits of its multinationals corporations and financial capital, by means of the international sub-traction of profitable assets, such as financial, energetic, communicational and natural resources, in addition to the domination of local markets, beyond facilitating capital flee amongst others.