PARA UMA POÉTICA DA VITALIDADE: religião e antropologia na escritura machadiana (Uma leitura de Memórias póstumas de Brás Cubas, de Machado de Assis)

A literatura de Machado de Assis foi revisitada nesta tese porque tínhamos a convicção de que o tema da religião e suas implicações para o ser humano machadiano se constituíam como uma tarefa de investigação que esperava por ser feita. Para localizar o objetivo central da presente tese no campo das discussões travadas entre religião e literatura construímos, na primeira parte, um caminho que nos levou a constatação da efetiva aproximação entre elas. Amparados pela inabarcável discussão que trata das imagens religiosas e teológicas presentes nos textos literários, bem como pelas inúmeras construções metodológicas que visam a propiciar uma aproximação mais profícua entre religião e literatura, buscamos uma interpretação da literatura machadiana que apontasse para a expressão religiosa do ponto de vista de sua antropologia. O nosso eixo interpretativo foi construído a partir da teoria hermenêutica de Paul Ricoeur, mais especificamente a partir do conceito de metáfora. A reflexão que construímos em torno da expressão religiosa da antropologia machadiana foi inicialmente devedora do conceito de vitalidade de Jürgen Moltmann. A expressão religiosa da antropologia machadiana emergida do romance Memórias Póstumas de Brás Cubas (1881) apresenta-se sob a perspectiva de uma incondicionalidade a partir da qual a vida de Brás Cubas é tomada. Esta característica da antropologia machadiana fez com que estabelecêssemos um recurso conceitual para dar conta de sua particularidade. Propomos, portanto, que o ser humano do espaço literário machadiano seja chamado de homo vitalis.(AU)

PARA UMA POÉTICA DA VITALIDADE: religião e antropologia na escritura machadiana (Uma leitura de Memórias póstumas de Brás Cubas, de Machado de Assis)

A literatura de Machado de Assis foi revisitada nesta tese porque tínhamos a convicção de que o tema da religião e suas implicações para o ser humano machadiano se constituíam como uma tarefa de investigação que esperava por ser feita. Para localizar o objetivo central da presente tese no campo das discussões travadas entre religião e literatura construímos, na primeira parte, um caminho que nos levou a constatação da efetiva aproximação entre elas. Amparados pela inabarcável discussão que trata das imagens religiosas e teológicas presentes nos textos literários, bem como pelas inúmeras construções metodológicas que visam a propiciar uma aproximação mais profícua entre religião e literatura, buscamos uma interpretação da literatura machadiana que apontasse para a expressão religiosa do ponto de vista de sua antropologia. O nosso eixo interpretativo foi construído a partir da teoria hermenêutica de Paul Ricoeur, mais especificamente a partir do conceito de metáfora. A reflexão que construímos em torno da expressão religiosa da antropologia machadiana foi inicialmente devedora do conceito de vitalidade de Jürgen Moltmann. A expressão religiosa da antropologia machadiana emergida do romance Memórias Póstumas de Brás Cubas (1881) apresenta-se sob a perspectiva de uma incondicionalidade a partir da qual a vida de Brás Cubas é tomada. Esta característica da antropologia machadiana fez com que estabelecêssemos um recurso conceitual para dar conta de sua particularidade. Propomos, portanto, que o ser humano do espaço literário machadiano seja chamado de homo vitalis.(AU)

A nucleolar protein related to ribosomal protein L7 is required for an early step in large ribosomal subunit biogenesis

The Saccharomyces cerevisiae Rlp7 protein has extensive identity and similarity to the large ribosomal subunit L7 proteins and shares an RNA-binding domain with them. Rlp7p is not a ribosomal protein; however, it is encoded by an essential gene and therefore must perform a function essential for cell growth. In this report, we show that Rlp7p is a nucleolar protein that plays a critical role in processing of precursors to the large ribosomal subunit RNAs. Pulse–chase labeling experiments with Rlp7p-depleted cells reveal that neither 5.8SS, 5.8SL, nor 25S is produced, indicating that both the major and minor processing pathways are affected. Analysis of processing intermediates by primer extension indicates that Rlp7p-depleted cells accumulate the 27SA3 precursor RNA, which is normally the major substrate (85%) used to produce the 5.8S and 25S rRNAs, and the ratio of 27SBL to 27SBS precursors changes from approximately 1:8 to 8:1 (depleted cells). Because 27SA3 is the direct precursor to 27SBS, we conclude that Rlp7p is specifically required for the 5′ to 3′ exonucleolytic trimming of the 27SA3 into the 27SBS precursor. As it is essential for processing in both the major and minor pathways, we propose that Rlp7p may act as a specificity factor that binds precursor rRNAs and tethers the enzymes that carry out the early 5′ to 3′ exonucleolytic reactions that generate the mature rRNAs. Rlp7p may also be required for the endonucleolytic cleavage in internal transcribed spacer 2 that separates the 5.8S rRNA from the 25S rRNA.

Differential Control of Xanthophylls and Light-Induced Stress Proteins, as Opposed to Light-Harvesting Chlorophyll a/b Proteins, during Photosynthetic Acclimation of Barley Leaves to Light Irradiance

Barley (Hordeum vulgare L.) plants were grown at different photon flux densities ranging from 100 to 1800 μmol m−2 s−1 in air and/or in atmospheres with reduced levels of O2 and CO2. Low O2 and CO2 partial pressures allowed plants to grow under high photosystem II (PSII) excitation pressure, estimated in vivo by chlorophyll fluorescence measurements, at moderate photon flux densities. The xanthophyll-cycle pigments, the early light-inducible proteins, and their mRNA accumulated with increasing PSII excitation pressure irrespective of the way high excitation pressure was obtained (high-light irradiance or decreased CO2 and O2 availability). These findings indicate that the reduction state of electron transport chain components could be involved in light sensing for the regulation of nuclear-encoded chloroplast gene expression. In contrast, no correlation was found between the reduction state of PSII and various indicators of the PSII light-harvesting system, such as the chlorophyll a-to-b ratio, the abundance of the major pigment-protein complex of PSII (LHCII), the mRNA level of LHCII, the light-saturation curve of O2 evolution, and the induced chlorophyll-fluorescence rise. We conclude that the chlorophyll antenna size of PSII is not governed by the redox state of PSII in higher plants and, consequently, regulation of early light-inducible protein synthesis is different from that of LHCII.

Magnetic resonance imaging (MRI) detection of the murine brain response to light: temporal differentiation and negative functional MRI changes.

Using a 9.4 T MRI instrument, we have obtained images of the mouse brain response to photic stimulation during a period between deep anesthesia and the early stages of arousal. The large image enhancements we observe (often >30%) are consistent with literature results extrapolated to 9.4 T. However, there are also two unusual aspects to our findings. (i) The visual area of the brain responds only to changes in stimulus intensity, suggesting that we directly detect operations of the M visual system pathway. Such a channel has been observed in mice by invasive electrophysiology, and described in detail for primates. (ii) Along with the typical positive response in the area of the occipital portion of the brain containing the visual cortex, another area displays decreased signal intensity upon stimulation.

TENDENCIA THATCHERITIS OR ENGLISHNESS REMADE: The Fictions of Julian Barnes, Hanif Kureishi and Pat Barker

Julian Barnes, Pat Barker, and Hanif Kureishi are all canonical authors whose fictions are widely believed to reflect the cultural and political state of a nation that is post-war, post-imperial and post-modern. While much has been written on how Barker’s and Kureishi’s early works in particular respond to and intervene in the presiding political narrative of the 1980s – Thatcherism – treatment of how revenants of Thatcherism have shaped these writers’ works from 1990 on has remained cursory. Thatcherism is more than an obvious historical reference point for Barker, Barnes, and Kureishi; their works demonstrate a sophisticated understanding of how Thatcher’s reworkings of the repertoires of Englishness – a representational as well as political and cultural endeavour – persist beyond her time in office. Barnes, Barker, and Kureishi seem to have reached the same conclusion as political and cultural critics: Thatcher and Thatcherism have remade not only the contemporary political and cultural landscapes but also the electorate and consequently the English themselves. Tony Blair’s conception of the New Britain proved less than satisfactory because contemporary repertoires of Englishness repeat and rework historical and not incidentally imperial formulations of England and Englishness rather than envision civic and populist formulations of renewal. Barnes’s England, England and Arthur & George confront the discourse of inevitability that has come to be attached to contemporary formulations of both political and cultural Englishness – both in terms of its predictable demise and its belated celebration. Kureishi’s The Buddha of Suburbia and “The Body” speak to an alteration that has taken place in which historical Englishness and Thatcherism have become complementary rather than contrasting discourses. What Barker’s Border Crossing and Double Vision offer against this backdrop is a subtle interrogation of how renewal itself comes to be a presiding mode of cultural reflection that absorbs revolutionary possibility.

Five things we need to know about the on-demand economy. CEPS Essay No. 21/8 January 2016

The last few years have witnessed the exponential growth of platforms like Uber and Airbnb and the creation of countless other less well-known examples. The expansion of the on-demand economy puts huge pressure on regulators to adapt it to the existing frameworks for labour and taxation. The rapid growth of the sector also divides experts: it is seen by many as threat for working conditions, and by others as an incredible opportunity. The purpose of this essay is to take a balanced perspective on what we know about the on-demand economy and what needs further investigation. More research is needed on the individual cases before one can draw conclusions on how this new sector works. The political economy of the sector is made even more interesting by the fact that the technology is developing faster than the regulation. Yet, our plea to policy-makers is to refrain from legislating too early and to take the time to understand how the supply and the demand of these services behave and their equilibrium.

Sermons on practical subjects: to which is added, a farewell discourse, delivered at Paisley in April and May 1768.

Mode of access: Internet.

The Ante-Nicene fathers. Translations of the writings of the fathers down to A.D. 325.

First published under title: Ante-Nicene Christian library.

The itinerary of John Leland in or about the years 1535-1543, parts I to [XI]

"Comparative table of the MSS. and editions": v. 1, p. [xxxvi]

Sämmtliche Schriften des heiligen Hilarius, Bischofs von Poitiers.

In Sämtliche Werke der Kirchenväter, v.7, pp.333-386; 8-12; 13, pp.1-222.

A supplement to Allibone's Critical dictionary of English literature and British and American authors : Containing over thirty-seven thousand articles (authors), and enumerating over ninety-three thousand titles /

Mode of access: Internet.

Introduction to the literature of Europe in the 15th, 16th, and 17th centuries./

Vols. 2-4 have half-title: Collection of ancient and modern British authors. v. 166-167 bis.

Ante-Nicene Christian library; translations of the writings of the Fathers down to A. D. 325,

Mode of access: Internet.

The Ante-Nicene Fathers; translations of the writings of the Fathers down to A. D. 325.

First published under title: Ante-Nicene Christian library.