Growth, Poverty and Inequality in the Caribbean

.--Director’s Desk: Growth, Poverty and Inequality in the Caribbean.--Non-Comunicable Diseases: A Growing Epidemic.--Policies and Programmes for an Ageing Population.--Sexual and Reproductive Health and HIV in the Caribbean.--International Migration and Development: Challenges and Opportunites.--Gender Based Violence

Aspectos fisiologicos e bioqímicos da enxertia em plantas de pepino

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Trabalhadoras e economia solidária na associação de mulheres do município de Igarapé-Miri/Asmim-Pará: da resistência à estratégia de desenvolvimento local

O presente estudo retrata a constituição da Associação de Mulheres do Município de Igarapé-Miri –ASMIM/Pará, como um espaço de lutas, resistências e associativismo de mulheres trabalhadoras. Visa contribuir com o debate acerca das conquistas de uma experiência prática coletiva, na construção do desenvolvimento local, em Igarapé-Miri. Para isso, procurou-se nesta pesquisa entender o cenário da economia solidária, bem como, as diferentes concepções que giram em torno dessa temática em interface com o desenvolvimento local, à medida que, se entende ambas, como estratégias importantes para a constituição da mulher enquanto um sujeito coletivo capaz de romper com a invisibilidade e empoderar-se, no sentido de se tornar protagonista de sua própria história. Ressaltou-se importantes momentos de lutas e resistências femininas em torno de igualdade de direitos, geração de renda e participação na vida pública. Nesse sentido, a ênfase das organizações e movimentos sociais aos quais essas mulheres estiveram/estão articuladas foi importante para compreender de que forma elas foram galgando seu espaço de representação política em nível local, regional e nacional, ou seja, demonstrando novas práticas sócio-econômicas e político-culturais em que se tornaram referências e alteram a realidade do seu papel na sociedade contemporânea. Por fim, realçou-se que essa construção em Igarapé-Miri foi/é de muitas lutas, e, por conseguinte, conflitos que se expressam em âmbito familiar e de trabalho evidenciando desigualdades existentes e, muitas vezes, escamoteadas. Esta pesquisa traz para o debate os princípios de economia solidária, enquanto ambiente propício ao empoderamento das mulheres, de estratégia para um desenvolvimento local e de visibilidade pública para essas mulheres.

Transverse maxillary and mandibular growth during and after Bionator therapy: study with metallic implants

INTRODUCTION: This study evaluated posteroanterior cephalograms before and after treatment and long term follow-up of Class II division 1 patients treated with bionator. OBJECTIVE: The objective was to demonstrate the transverse growth of maxilla and mandible during and after bionator therapy. METHODS: Measurement of transverse dimensions between posterior maxillary and mandibular implants, as well as the distances between the buccal, gonial and antegonial points were recorded. Measurements were analyzed at three periods: T1 = before bionator therapy, T2 = after bionator therapy and T3 = 5.74 years after T2. RESULTS: There was statistically significant transverse increase due to growth and/or treatment for all variables, except for the distance between the anterior maxillary implants. CONCLUSIONS: During the study period only the anterior maxillary area did not show transverse growth.

Development and validation of a microbiological assay by turbidimetry to determine the potency of cefazolin sodium in the lyophilized powder form

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Transcriptional Activity, Chromosomal Distribution and Expression Effects of Transposable Elements in Coffea Genomes

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Seedling Development and Evaluation of Genetic Stability of Cryopreserved Dendrobium Hybrid Mature Seeds

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Synthesis and tripanocidal activity of ferrocenyl and benzyl diamines against Trypanosoma brucei and Trypanosoma cruzi

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Development and characterization of biocompatible isotropic and anisotropic oil-in-water colloidal dispersions as a new delivery system for methyl dihydrojasmonate antitumor drug

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Growth performance and meat quality of heifers receiving different forms of soybean oil in the rumen

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Glutamatergic antagonism in the NTS decreases post-inspiratory drive and changes phrenic and sympathetic coupling during chemoreflex activation

For a better understanding of the processing at the nucleus tractus solitarius (NTS) level of the autonomic and respiratory responses to peripheral chemoreceptor activation, herein we evaluated the role of glutamatergic neurotransmission in the intermediate (iNTS) and caudal NTS (cNTS) on baseline respiratory parameters and on chemoreflex-evoked responses using the in situ working heart-brain stem preparation (WHBP). The activities of phrenic (PND), cervical vagus (cVNA), and thoracic sympathetic (tSNA) nerves were recorded before and after bilateral microinjections of kynurenic acid (Kyn, 5 nmol/20 nl) into iNTS, cNTS, or both simultaneously. In WHBP, baseline sympathetic discharge markedly correlated with phrenic bursts (inspiration). However, most of sympathoexcitation elicited by chemoreflex activation occurred during expiration. Kyn microinjected into iNTS or into cNTS decreased the postinspiratory component of cVNA and increased the duration and frequency of PND. Kyn into iNTS produced no changes in sympathoexcitatory and tachypneic responses to peripheral chemoreflex activation, whereas into cNTS, a reduction of the sympathoexcitation, but not of the tachypnea, was observed. The pattern of phrenic and sympathetic coupling during the chemoreflex activation was an inspiratory-related rather than an expiratory-related sympathoexcitation. Kyn simultaneously into iNTS and cNTS produced a greater decrease in postinspiratory component of cVNA and increase in frequency and duration of PND and abolished the respiratory and autonomic responses to chemoreflex activation. The data show that glutamatergic neurotransmission in the iNTS and cNTS plays a tonic role on the baseline respiratory rhythm, contributes to the postinspiratory activity, and is essential to expiratory-related sympathoexcitation observed during chemoreflex activation.

Effects of FGF10 on bovine oocyte meiosis progression, apoptosis, embryo development and relative abundance of developmentally important genes in vitro

Contents Fibroblast growth factor (FGF10) acts at the cumulus oocyte complex, increasing the expression of cumulus cell expansion-related genes and oocyte competency genes. We tested the hypothesis that addition of FGF10 to the maturation medium improves oocyte maturation, decreases the percentage of apoptotic oocytes and increases development to the blastocyst stage while increasing the relative abundance of developmentally important genes (COX2, CDX2 and PLAC8). In all experiments, oocytes were matured for 22h in TCM-199 supplemented with 0, 2.5, 10 or 50ng/ml FGF10. In Experiment 1, after maturation, oocytes were stained with Hoechst to evaluate meiosis progression (metaphase I, intermediary phases and extrusion of the first polar body) and submitted to the TUNEL assay to evaluate apoptosis. In Experiment 2, oocytes were fertilized and cultured to the blastocyst stage. Blastocysts were frozen for analysis of COX2, CDX2 and PLAC8 relative abundance. In Experiment 1, 2.5ng/ml FGF10 increased (p<0.05) the percentage of oocytes with extrusion of the first polar body (35%) compared to 0, 10 and 50ng/ml FGF10 (21, 14 and 12%, respectively) and FGF10 decreased the percentage of oocytes that were TUNEL positive in all doses studied. In Experiment 2, there was no difference in the percentage of oocytes becoming blastocysts between treatments and control. Real-time RT-PCR showed a tendency of 50ng/ml FGF10 to increase the relative abundance of COX2 and PLAC8 and of 10ng/ml FGF10 to increase CDX2. In conclusion, the addition of FGF10 to the oocyte maturation medium improves oocyte maturation in vitro, decreases the percentage of apoptotic oocytes and tends to increase the relative abundance of developmentally important genes.