Hinnë woauhel : "Hier ist sie (Mutter Sarah) im Zelte" ; (1. B. M. 18,9) Vorschriften für den jüdischen Haushalt

in populärer Form dargest. u. mit kurzen Erklärungen versehen von Ansbacher. Hrsg. vom "Württemberger gesetzestreuen Landesverband"

Qineat-emet (Wahrheitseifer) oder: offener Brief an A. Hochmuth als apologetische Entgegung auf seinen in der "Neuzeit" Nr. 18 a. c. gegen d. Werk Pi Senajim geschleuderten Angriff

von Kálmán Weiss

Jüdische Reformbestrebungen im 19. Jahrhundert : Vortr., geh. am 23 April 1907 im israel. Humanitätsvereine Wien B'nai B'rith

von Wilhelm Knöpfmacher

Abhandlung über den Ursprung der Beschneidung bei wilden und halbwilden Völkern mit Beziehung auf die Beschneidung der Israeliten : mit e. Kritik von C. Chr. v. Flatt begleitet

verf. von J. H. F. v. Autenrieth

Kurtzer bewehrter Ausszuch [et]c. Der letzten Wormbser Judenordnung, wie sie Anno 1594. an etlichen orten Corrigiert vnd gebessert, im Newlich eröffneten Buchstaben geschrieben befunden : Darinnen ein jeder aussgesessener vnnd vnparteischer Christ: oder hanthierender Burger zu Wormbs, sich zubespieglen ... habe [et]c.

Vorlageform des Erscheinungsvermerks: Gedruckt zu Vallo Francko, Anno 1614.

Żydzi Lwowscy na przełomie XVIgo i XVIIgo wieku : praca odznaczona pierwszą nagrodą na konkursie im. H. Wawelberga przez wydział filozoficzny C. K. Uniwersytetu Lwowskiego

Majer Bałaban

A Jewish Calendar for sixtyfour years, detailing the new moons, festivals, and fasts : ... to which are added tabl. for continuing the calendar to A. M. 6000-2240 C. Ae. and a chronological table ...

by E. H. Lindo

J. C. E. Michaelsen og hustrus forfaedre

[Josef Fischer]

Traktat über die Neulichtbeobachtung und den Jahresbeginn bei den Karäern von Samuel b. Moses

nach e. arabischen Handschrift mit dem Fragmente e. hebräischen Übers. kritisch hrsg. u. ins Dt. übertr. von Felix Kauffmann

Offener Brief an Se. Ehrwürden Herrn Distrikts-Rabbiner S. B. Bamberger in Würzburg

von Samson Raphael Hirsch

Ḥamiššā ḥūmšê Tôrā bi-lšôn aškenaz : ṣe'ênā û-re'ênā benôt Ṣiyyôn bā-ʿaṭārā

še-ʿiṭṭēr lākem ... Yaʿaqôv Ben- ... Yiṣḥāq ... mim-mišpaḥat rabbēnû ... be-q"q Yānôw

Organization of the equine immunoglobulin heavy chain constant region genes; III. Alignment of c mu, c gamma, c epsilon and c alpha genes.

Previous restriction analysis of cloned equine DNA and genomic DNA of equine peripheral blood mononuclear cells had indicated the existence of one c epsilon, one c alpha and up to six c gamma genes in the haploid equine genome. The c epsilon and c alpha genes have been aligned on a 30 kb DNA fragment in the order 5' c epsilon-c alpha 3'. Here we describe the alignment of the equine c mu and c gamma genes by deletion analysis of one IgM, four IgG and two equine light chain expressing heterohybridomas. This analysis establishes the existence of six c gamma genes per haploid genome. The genomic alignment of the cH-genes is 5' c mu/(/) c gamma 1/(/) c gamma 2/(/) c gamma 3/(/) c gamma 4/(/) c gamma 5/(/) c gamma 6/(/) c epsilon-c alpha 3', naming the c gamma genes according to their position relative to c mu. For three of the c gamma genes the corresponding IgG isotypes could be identified as IgGa for c gamma 1, IgG(T) for c gamma 3 and IgGb for c gamma 4.

The main principles of the creed and ethics of the Jews : exhibited in selections from the Yad hachazakah of Maimonides ; with a literal English translation, copious illustrations from the Talmud, & c.

by Hermann Hedwig Bernard

Dysregulated CD40-NF-kappaB signaling in the pathophysiology of aggressive non -Hodgkin's lymphoma B cells

Non-Hodgkin's Lymphomas (NHL) are a group (>30) of important human lymphoid cancers that unlike other tumors today, are showing a marked increase in incidence. The lack of insight to the pathogenesis of B-cell NHL poses a significant problem in the early detection and effective treatment of these malignancies. This study shows that large B-cell lymphoma (LBCL) cells, the most common type of B-cell NHL (account for more than 30% of cases), have developed a novel mechanism for autonomous neoplastic B cell growth. We have identified that the key transcription factor NF-κB, is constitutively activated in LBCL cell lines and primary biopsy-derived LBCL cells, suggesting that they are autonomously activated, and do not require accessory T-cell signaling for cell growth and survival. Further studies have indicated that LBCL cells ectopically express an important T-cell associated co-mitogenic factor, CD154 (CD40 ligand), that is able to internally activate the CD401NF-κB pathway, through constitutive binding to its cognate receptor, CD40, on the lymphoma cell surface. CD40 activation triggers the formation of a “Signalosome” comprising virtually the entire canonical CD40/NF-κB signaling pathway that is anchored by CD40 in plasma membrane lipid rafts. The CD40 Signalosome is vulnerable to interdiction by antibody against CD40 that disrupts the Signalosome and induces cell death in the malignant cells. In addition to constitutive NF-κB activation, we have found that the nuclear factor of activated T cells (NFAT) transcription factor is also constitutively activated in LBCL cells. We have demonstrated that the constitutively active NFATc1 and c-rel members of the NFAT and NF-κB families of transcription factors, respectively, interact with each other, bind to the CD154 promoter, and synergistically activate CD154 gene transcription. Down-regulation of NFATc1 and c-rel with small interfering RNA inhibits CD154 gene transcription and lymphoma cell growth. Our findings suggest that continuous CD40 activation not only provides dysregulated proliferative stimuli for lymphoma cell growth and extended tumor cell survival, but also allows continuous regeneration of the CD40 ligand in the lymphoma cell and thereby recharges the system through a positive feedback mechanism. Targeting the CD40/NF-κB signaling pathway could provide potential therapeutic modalities for LBCL cells in the future. ^