Estudo de caso: aplicação do método DMAIC-White Belt- na redução de latas amassadas em uma produção de leite em pó

This work consists of the implementation of the steps Define, Measure , Analyze , Improve and Control ( DMAIC ) to develop a Six Sigma project in an industry the food industry. The objective was to demonstrate a potential for reducing the occurrence of crushed cans in potting milk powder industry in a White Belt project. The food industry accounts for about 9 % of Brazil's gross domestic product ( GDP ), generating thousands of jobs . Among the major sectors of the food industry is the manufacturing sector of milk , occupies approximately 10 % of the total turnover of the food industry . Brazil is considered today one of the eight largest producers of milk powder in the world. The milk powder is packed , mostly for aluminum cans that are lined internally with varnishes and other materials to protect the milk of metals from aluminum. When the cans are dented food protection is compromised and may lead ingestion causing dis-eases such as botulism. Aiming to solve the problem of dented cans methodology was used as a case study with a quantitative approach through the DMAIC method. Some quality tools used in each step of the project as brainstorming , cause and effect diagram , flowchart , ef-fort and impact matrix, 5W1H , among other Pareto diagram is presented . A survey about the disposal of cans in the company verifying a mean loss and, from this histor-ical , a goal loss was calculated was performed . With the target set we calculated the annual saving design . During application of DMAIC was found that the highest rate of loss occurred in transportation between the factory and the factory that fills cans milk . Several actions were taken to resolve problems that resulted in dented cans and the first two months of phase control it was found that the smaller losses calculated target resulting in a saving for the company. The short time of implementa-tion of the Improve phase did not allow a more detailed a ...

Utilização do método de tomada de decisão multicritério PROMETHEE II para priorização do plano de ação de redução de custos de manutenção

In the last years, the maintenance took an essential role inside the productive system. Plan and manage the maintenance actions in an efficient way, are vital activities for higher production availability. This paper presents an application of a Multicriteria Decision Analysis method in a chemical industry, willing to priories a plan action for the reduction of the maintenance cost. The method used was the PROMETHEE II, with it the results were obtained through the softwares Microsoft Excel and Decision Lab

Diabete moderado induzido em diferentes fases da vida de ratas Wistar: repercussões na reprodução materna e na freqüência de anomalias fetais

Experimental models are necessary to elucidate pathophysiological mechanisms not yet understood in humans. To evaluate the repercussions of the diabetes, considering two methodologies, on the pregnancy of Wistar rats and on the development of their offspring. In the 1st induction, female offspring were distributed into two experimental groups: Group streptozotocin (STZ, n=67): received the β-cytotoxic agent (100mg STZ/kg body weight - sc) on the 1st day of the life; and Non-diabetic Group (ND, n=14): received the vehicle in a similar time period. In the adult life, the animals were mated. After a positive diagnosis of pregnancy (0), female rats from group STZ presenting with lower glycemia than 120 mg/dL received more 20 mg STZ/kg (ip) at day 7 of pregnancy (2nd induction). The female rats with glycemia higher than 120mg/dL were discarded because they reproduced results already found in the literature. In the mornings of days 0, 7, 14 and 21 of the pregnancy glycemia was determined. At day 21 of pregnancy (at term), the female rats were anesthetized and killed for maternal reproductive performance and fetal development analysis. The data were analyzed using Student-Newman-Keuls, Chi-square and Zero-inflated Poisson (ZIP) Tests (p<0.05). STZ rats presented with increased rates of pre (STZ=22.0%; ND=5.1%) and post-implantation losses (STZ=26.1%; ND=5.7%), reduced rates of fetuses with appropriate weight for gestational age (STZ=66%; ND=93%) and reduced degree of development (ossification sites). Conclusion: Mild diabetes led a negative impact on maternal reproductive performance and caused intrauterine growth restriction and impaired fetal development

Projeto DMAIC com ferramentas six sigma para redução de custos logísticos de uma multinacional

This work has a focus on project execution DMAIC ( Define Measure Analyze Implement Control) , using the statistical and quality tools to identify , analyze and implement improvements in a given process in order to reduce costs telephony transport of a multinational consumer goods . The multinational consumer goods to be studied has outsourced carriers who perform the distribution of its products , which may lead them straight to their factories or one of its distribution centers to the points of sale ( supermarkets , bakeries , gas stations , convenience cafeterias , among others ) . Whenever there is an unexpected situation or some problem at the time of delivery of the goods to the customer opens an occurrence , ie , the carrier responsible for contacts ( 0800 ) with the contact center company of consumer goods which in turn registers the occurrence, analyzes and sends a response action to the carrier . This work will study the problem with a high number of connections to handle occurrence , through analysis and data collection , identify improvement opportunities, implement them and monitor the results to ensure that the gain and loss reduction are sustainable

Análise da influência da iluminação de rodovias federais com a redução do número de acidentes

The increasing rate of traffic accidents, followed by the high rate of mortality due to these occurrences, favored to the classification of traffic accidents as a public health problem in Brazil. These accidents consume a significant portion of Gross Domestic Product (GDP), especially related to the victims. Considering this scenery with many tragedies and resources being spent only in the end, this paper seeks to examine the influence of federal highways lighting by reducing the number of accidents. Federal Highways sections that received lighting were taken up for study, therefore a survey of statistical data has been raised considering the accidents before and after the route had been illuminated. Taking advantage of the results obtained, an economic analysis has been made considering the amounts consumed by traffic accidents versus the values required for the installation of lighting on highways

Intervenção com Azadirachta indica (Neem) na prenhez de ratas diabéticas: repercussões materno-fetais

Objetivo: Considerando o uso indiscriminado de diversas plantas para o tratamento de doenças, o objetivo deste estudo foi analisar os efeitos da Azadirachta indica (Neem) sobre a glicemia e performance reprodutiva materna de ratas normoglicêmicas e com diabete moderado. Material e Método: O diabete foi induzido em ratas fêmeas no dia do nascimento com streptozotocin (100mg/kg de peso corpóreo, via subcutânea). O grupo não-diabético (controle) recebeu como veículo o tampão citrato com dose e via similares ao grupo diabético. Na fase adulta, ratas não-diabéticas e diabéticas foram acasaladas com machos normoglicêmicos. Durante todo o período de prenhez, as ratas foram tratadas com o princípio ativo (Azadirachtina) ou óleo da semente de Azadirachta indica (Neem). As glicemias foram mensuradas nos dias 0, 7, 14 e 20 de prenhez e o teste oral de tolerância à glicose no 17º dia. Ao final da prenhez, foi realizada laparotomia para contagem de fetos vivos e mortos, corpos lúteos, implantações e de reabsorções (mortes embrionárias). Os descendentes foram analisados quanto à presença de anomalias externas e internas (esqueléticas e viscerais). Para limite de significância estatística foi considerado p<0,05. Resultados: Os tratamentos com o óleo e princípio ativo causaram maior intolerância à glicose em ratas diabéticas, prejuízos no desempenho reprodutivo materno e anormalidades esqueléticas e viscerais fetais. Conclusão: Os diferentes tratamentos não apresentaram efeito antidiabético e causaram efeitos adversos no desempenho reprodutivo materno e no desenvolvimento dos fetos. Sendo assim, este estudo mostrou que o uso indiscriminado de plantas medicinais, principalmente por mulheres grávidas, pode ser prejudicial para o desenvolvimento intrauterino

Redução do tempo de ciclo baseado na produção enxuta em uma rémontagem de tubos de freios e combustível

In today's competitive environment of automakers, it is essential to obtain the highest efficiency of the production process. This paper presents a study in a pre-assembly of brake pipes and fuel of a vehicle where the value stream maps and information (VSM – Value Stream Mapping) were designed in order to improve the process by reducing the Lead Time Production of a product, reducing waste and decrease time between processes. This work can be divided into three stages, the first building the VSM of the initial state, the second VSM of the proposed state and finally the VSM than was actually performed and to present the gains were achieved effectively. The proposed VSM would lead to a gain of 54% in lead time and 61% in processing time, since the VSM implemented had gains of 47% in lead time and 48% in processing time even without major investments as originally proposed. Concluding that even without big investment, using the techniques of lean manufacturing is possible to achieve high levels of process efficiency

Avaliação da exposição ao propionato de testosterona em ratas fêmeas in utero e lactação

It is known that exposure to substances in the environment can contribute to various reproductive disorders, especially if such exposure occurs during critical periods of development such as the intra-uterine and postnatal. The female reproductive system may be the target of androgens, both as a result of exposure to environmental chemicals, or by pathological conditions (polycystic ovary syndrome or congenital adrenal hyperplasia).Usually, little attention is given off in relation to the study of androgenic effects in the female reproductive axis. This study aims to evaluate the effects of exposure to androgens on the development, structure and reproductive function in rats whose mothers were exposed to testosterone propionate from gestational day 12 (DG12) after weaning - postnatal day 21 (DPN21) . For this purpose, pregnancy rats were divided into four groups: a control group that received corn oil (vehicle) and three groups receiving testosterone propionate in doses of 0.05 mg / kg / day, 0.1 mg / kg / day and 0.2 mg / kg / day, all under the same experimental conditions. The possible effects of exposure were assessed using reproductive parameters, such as a measure of anogenital distance, count areolas / nipples, age at vaginal opening and first estrus (puberty indicative installation), weight and histological evaluation of the reproductive organs ( uterus and ovaries), weight of the kidneys, liver and pituitary hormone levels, regularity of the estrous cycle, sexual behavior and fertility. Such analysis is important in understanding the effects of androgen exposure on the female genital system, especially on the reproductive potential, and processes that may involve morphofunctional changes. In these experimental conditions, it is concluded that treatment with PT caused reduction in body weight and initial masculinization in females without cubs, however, commit further sexual development

Redução do tempo de setup de máquinas de usinagem em uma industria automobilística

Continuous improvement of industrial processes is one way to become companies more competitive in the market. For this, a fairly widespread use is the methodology of lean production systems, by eliminating waste. One of the tools of these systems is the method of rapid exchange of die or also called SMED, which will be applied in this study. The study aims to develop proposals for reducing the time of set up of two machines in two machining lines, watching also the ergonomics and safety conditions in this operations. The set up time reduction is justified among others, due to increase the machine productivity. In applying the connecting rod machining line, there were two types of exchange. Reductions in time to set up proposals reached values of 47% to one of them, and 55% to the other. It is important to underline that to reach this result, there was no need for large investments. In the application in block machining line, was developed an improvement in the ergonomic area. It was placed a pulley block that came to increase the time of tool change. Aiming to improve the security of the exchange, without productivity loss, the method was applied to reduce this time. It was developed two proposals.: the first would reduce that time by 19%, and does not require many resources of the company. The second involves the parallelization of the exchange, so that the reduction is 48%. However, this proposal requires one more manpower at the time of exchange and it is not always possible

Redução de tempo de setup de uma máquina de encartuchamento pela técnica SMED

Currently the market requires companies to adapt for they can have the lowest possible cost in their manufacturing, be it a good or service, thus obtaining a greater profit. For this profit the Toyota Production System applies lean manufacturing practices actions with reduced spending, smaller lots and stocks, generated by market demand. The technique allows SMED with few actions, changes and investments that time does not exceed one digit on your total time. This case study shows that only with standardization and use of inexpensive improvements, could reduce setup time on a machine for 70 minutes to time of approximately 48 minutes with little investment, demonstrating the viability of the tool presented

Redução dimensional de partículas de spin s=0,s=1 e s=2 via mecanismo de Kaluza-Klein

In this graduate work we will perform the dimensional reduction of particles of spin s=0, s=1 and s=2 via Kaluza Klein mechanism. The method of Kaluza-Klein dimensional reduction is introduced by the dimensional reduction from D to D

Teorias de Spin-1: decomposição em helicidades, redução dimensional e imersão de calibre

We have studied the physical content of the following models: Maxwell, Proca, Self-Dual and Maxwell-Chern-Simons. One method we have used is the decomposition in the so called helicity variables, which can be done in the Lagrangian formalism. It leads to the correct counting of degrees of freedom without choosing a gauge condition. The method separates the propagating modes from the non-propagating ones. The Hamiltonian of the MCS and the AD is calculated. The second method used here is the analysis of the sign of the imaginary part of the residues of the two-point amplitude of the theory, showing that the models analyzed are free of ghosts. We also carry the dimensional reduction of the Maxwell-Chern-Simons and Self-Dual models from D = 2+1 to D = 1 + 1 dimensions. Next, we show that the dimensional reduction of those equivalent models also leads to equivalent models in D=1+1. Even more interesting is the fact, demonstrated here, that those reduced models can also be connected via gauge embedding. So the gauge embedding of the Self-Dual model into the Maxwell-Chern-Simons theory is preserved by the dimensional reduction

Efeitos da corticoterapia pré-natal e durante a puberdade sobre a morfofisiologia do lobo ventral da próstata de ratos senis

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Toxicologia reprodutiva de ratos adultos expostos ao 2,3,7,8-Tetraclorodibenzo-P-Dioxina (TCDD) in útero

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Reparação óssea em alvéolos de ratas ovarectomizadas após implante com biovidro: análise histomorfométrica e imunoistoquímica

Pós-graduação em Odontologia - FOA