THE BACON CHOW STUDY: THE RELATIONSHIP BETWEEN INFECTIOUS ILLNESS AND GROWTH OF INFANTS

Multiple dietary deficiencies and high rates of infectious illness are major health problems leading to malnutrition and limitation of growth of children in developing countries. Longitudinal studies which provide information on illness incidence and growth velocity are needed in order to untangle the complex interrelationship between nutrition, illness and growth. From 1967 to 1973, researchers led by Dr. Bacon Chow of the Johns Hopkins University School of Hygiene undertook a quasi-experimental prospective study in Suilin Township, Taiwan to determine the effects of a nutritional supplement to the diets of pregnant and lactating women on the growth, development and resistance to disease of their offspring. This dissertation presents results from the analysis of infant morbidity and postnatal growth.^ Maternal nutritional supplementation has no apparent effect on the postnatal growth or morbidity of infants. Significant sex differences exist in growth response to illness and in illness susceptibility. Male infants have more diarrhea and upper respiratory illness. Respiratory illness is positively associated with growth rate in weight in the first semester of life. Diarrhea is significantly negatively associated with growth in length in the second semester. Small-for-date infants are more susceptible to illness in general and have a different pattern of growth response than large-for-date infants.^ Principal components analysis of illness data is shown to be an effective technique for making more precise use of ambiguous morbidity data. Multiple regression with component scores is an accurate method for estimating variance in growth rate predicted by indepenent illness variables. A model is advanced in which initial postnatal growth rate determines subsequent susceptibility to nutritional stress and infection. Initial growth rate is a function of prenatal nutrition, but is not significantly affected by maternal supplementation during gestation or lactation. Critical evaluation is made of nutritional supplementation programs which do not afford disease control.^

Comparison of methods for assessing in home night time crying in healthy infants

Background. Infant colic is a common condition that is thought to put infants at risk for Shaken Baby Syndrome, a particularly devastating form of child abuse. However, little research has been done on techniques parents can use to deal with infant colic. This pilot study was conducted to assess the equipment that will be used in a randomized control trial that will compare the results for two different techniques that parents can use to reduce crying in infants with colic. ^ Methods. A total of 11 healthy infants, between one and five months of age, were recruited into this pilot study. All infants had a dosimeter, actiwatch and maternal log placed into the home and a subset of infants (N=3) were also recorded by a video camera. The equipment recorded between 6pm and 6am for at least two and up to five nights. The maternal log and video log were compared with one another to determine if the maternal log provides an accurate representation of the infant's night-time activities (i.e. sleep, awake, crying, feeding). The maternal log was then compared to the dosimeter and actiwatch data to determine if the dosimeter/actiwatch accurately reproduce the maternal log. ^ Results. Data from 10 infants were included in the analyses. The maternal log and video log were in full or partial agreement 90% of the time. When comparing events noted by the mother, the maternal log and dosimeter data were in agreement 84% of the time, and the maternal log and actiwatch data were in agreement 87% of the time. In combination, the dosimeter and/or actiwatch data agreed with the maternal log 90% of the time. ^ Conclusions. Our preliminary analyses of these data suggest the dosimeter and actiwatch will be useful tool for defining infant sleep patterns relative to the maternal log. However further analysis will be required to develop threshold values that can be used to objectively define events in the proposed RCT. Such analyses will need to integrate data from multiple dosimeters and deal with the shifting baselines observed for both the dosimeter and actiwatch.^

A study of the association between timing of solid food introduction in infants and overweight and obesity in pre-school aged children in NHANES 2003-2008

Background. Previous studies suggest an association between timing of introduction of solid food and increased risk of obesity in pre-school aged children, but no study included a representative sample of US children. We sought to examine whether there was any association between the timing of solid food introduction and overweight/obesity in pre-school aged children. Design/methods. Cross-sectional study of a nationally representative sample (N=2050) of US children aged 2 to 5 years with information on infant feeding practices and measured weight and height from the National Health and Nutrition Examination Survey 2003–2008. The main outcome measure was BMI for age and sex ≥ 85th percentile. The main exposure was timing of solid food introduction at < 4, 4–5, or ≥ 6 months of age. Binomial logistic regression was used in the analysis controlling for child's sex, birth weight and breastfeeding status as well as maternal age at birth, smoking status and socio-demographic variables. Results. Two thousand and fifty children were included in the sample; 51% male and 49% female; 57.1% Non-Hispanic White, 21.9% Hispanic, 14.0% Non-Hispanic Black, and 7% other race/ethnicity. Twenty-two percent of the children were overweight or obese. Sixty-nine percent were breastfed or fed breast milk at birth and 36% continued breastfeeding for ≥ six months. Solid foods were introduced before 4 months of age for 11.2% of the children; 30.3% received solid foods between 4 to 5 months; with 58.6% receiving solid foods at 6 months or later. Timing of solid food introduction was not associated with weight status (OR= 1.36, 95% CI [0.83–2.24]). Formula-fed infants and infants breastfed for < 4 months had increased odds of overweight and obesity (OR=1.54, 95% CI [1.05–2.27] and OR= 1.60, 95% CI [1.05–2.44], respectively) when compared to infants breastfed for ≥ 6 months. Conclusion. Timing of solid food introduction was not associated with weight status in a national sample of US children ages 2 to 5 years. More focus should be placed on promoting breastfeeding and healthy infant feeding practices as strategies to prevent obesity in children. ^

Vitamin A supplementation in very low birth weight infants

PURPOSE: In United States, the percentage of Extremely Low Birth Weight (ELBW) born for year 2006 was 0.8% (approximately 32,000 babies) & Very Low Birth Weight (VLBW) 1.48% (1). ELBW babies account for nearly half (49%) of the infant mortality for United States. Very Low birth weight infants are at a significant risk for high mortality and morbidity due to their multi system involvement and predisposition to lung prematurity and impaired immune function. One of the common causes cited is Vitamin A deficiency (2, 3).The purpose of this study is to look at published literature on Vitamin A supplementation in very low birth weight (VLBW) infants. ^ RESEARCH DESIGN: Systematic review of literature of published articles meeting the pre-defined criteria. ^ PROCEDURE: Studies included in this review were those which looked at very low birth weight infants defined as birth weight<1500gms. All experimental studies were reviewed. Studies looking at the effect of Vitamin A supplementation in comparison with a placebo or by itself in varying dosing regimens as an intervention were reviewed. Vitamin A deficiency and its manifestations were of interest. We used key words such as "very low birth weight", "mortality", "Vitamin A", "retinol" and "supplementation" in our search. ^ RISKS & POTENTIAL BENEFITS: We do not see any potential risks associated with this study. The potential benefit is recommendation for future studies based on the review of literature available currently. ^ IMPORTANCE OF KNOWLEDGE THAT MAY REASONABLY BE EXPECTED TO RESULT: The systematic review of literature of all experimental studies in VLBW infants showed uniform correlation of parenteral Vitamin A dosing and high plasma concentrations achieved. The recommended dosage for use is 5000 IU 3 times/week given intramuscularly for 4 weeks to prevent CLD. Higher doses have not shown benefit, with a potential for toxicity, while lower doses are inadequate. There is no role of use of Vitamin A in closure of patent ductus arteriosus & reducing mortality. However, it is important to state that the number of studies done so far is limited with small sample sizes. There is a need in the future for experimental studies to ascertain the role of Vitamin A to improve outcomes in VLBW. Atleast, one more RCT should be conducted using the dosage recommended above to make this a standard practice.^

Associations between ambient levels of combustion pollutants and small for gestational age infants in Texas

There is scant evidence regarding the associations between ambient levels of combustion pollutants and small for gestational age (SGA) infants. No studies of this type have been completed in the Southern United States. The main objective of the project presented was to determine associations between combustion pollutants and SGA infants in Texas using three different exposure assessments. ^ Birth certificate data that contained information on maternal and infant characteristics were obtained from the Texas Department of State Health Services (TX DSHS). Exposure assessment data for the three aims came from: (1) U.S. Environmental Protection Agency (EPA) National Air Toxics Assessment (NATA), (2) U.S. EPA Air Quality System (AQS), and (3) TX Department of Transportation (DOT), respectively. Multiple logistic regression models were used to determine the associations between combustion pollutants and SGA. ^ For the first study looked at annual estimates of four air toxics at the census tract level in the Greater Houston Area. After controlling for maternal race, maternal education, tobacco use, maternal age, number of prenatal visits, marital status, maternal weight gain, and median census tract income level, adjusted ORs and 95% confidence intervals (CI) for exposure to PAHs (per 10 ng/m3), naphthalene (per 10 ng/m3), benzene (per 1 µg/m3), and diesel engine emissions (per 10 µg/m3) were 1.01 (0.97–1.05), 1.00 (0.99–1.01), 1.01 (0.97–1.05), and 1.08 (0.95–1.23) respectively. For the second study looking at Hispanics in El Paso County, AORs and 95% confidence intervals (CI) for increases of 5 ng/m3 for the sum of carcinogenic PAHs (Σ c-PAHs), 1 ng/m3 of benzo[a]pyrene, and 100 ng/m3 in naphthalene during the third trimester of pregnancy were 1.02 (0.97–1.07), 1.03 (0.96–1.11), and 1.01 (0.97–1.06), respectively. For the third study using maternal proximity to major roadways as the exposure metric, there was a negative association with increasing distance from a maternal residence to the nearest major roadway (Odds Ratio (OR) = 0.96; 95% CI = 0.94–0.97) per 1000 m); however, once adjusted for covariates this effect was no longer significant (AOR = 0.98; 95% CI = 0.96–1.00). There was no association with distance weighted traffic density (DWTD). ^ This project is the first to look at SGA and combustion pollutants in the Southern United States with three different exposure metrics. Although there was no evidence of associations found between SGA and the air pollutants mentioned in these studies, the results contribute to the body of literature assessing maternal exposure to ambient air pollution and adverse birth outcomes. ^

First -year mortality and survival among infants with selected congenital anomalies in Texas, 1995 to 1997

Congenital anomalies have been a leading cause of infant mortality for the past twenty years in the United States. Few registry-based studies have investigated the mortality experience of infants with congenital anomalies. Therefore, a registry-based mortality study was conducted of 2776 infants from the Texas Birth Defects Registry who were born January 1, 1995 to December 31, 1997, with selected congenital anomalies. Infants were matched to linked birth-infant death files from the Texas Department of Health, Bureau of Vital Statistics. One year Kaplan-Meier survival curves, and mortality estimates were generated for each of the 23 anomalies by maternal race/ethnicity, infant sex, birth weight, gestational age, number of life-threatening anomalies, prenatal diagnosis, hospital of birth and other variables. ^ There were 523 deaths within the first year of life (mortality rate = 191.0 per 1,000 infants). Infants with gastroschisis, trisomy 21, and cleft lip ± palate had the highest first year survival (92.91%, 92.32%, and 87.59%, respectively). Anomalies with the lowest survival were anencephaly (5.13%), trisomy 13 (7.41%), and trisomy 18 (10.29%). ^ Infants born to White, Non-Hispanic women had the highest first year survival (83.57%; 95% CI: 80.91, 85.88), followed by African-Americans (82.43%; 95% CI: 76.98, 86.70) and Hispanics (79.28%; 95% CI: 77.19, 81.21). Infants with birth weights ≥2500 grams and gestational ages ≥37 weeks also had the highest first year survival. First year mortality drastically increased as the number of life-threatening anomalies increased. Mortality was also higher for infants with anomalies that were prenatally diagnosed. Slight differences existed in survival based on infant's place of delivery. ^ In logistic regression analysis, birth weight (<1500 grams: OR = 7.48; 95% CI: 5.42, 10.33; 1500–2499 grams: OR = 3.48; 95% CI: 2.74, 4.42), prenatal diagnosis (OR = 1.92; 95% CI: 1.43, 2.58) and number of life-threatening anomalies (≥3: OR = 22.45; 95% CI: 11.67, 43.18) were the strongest predictors of death within the first year of life for all infants with selected congenital anomalies. To achieve further reduction in the infant mortality rate in the United States, additional research is needed to identify ways to reduce mortality among infants with congenital anomalies. ^

Conflictos entre pares en la escuela media. Reconstruyendo los sentidos de género que permean las relaciones juveniles

Este trabajo se propuso conocer sobre los sentidos de género que se implican en los modos en que alumnas/os perciben, justifican y actúan frente a los conflictos, recuperando sus voces y perspectivas. La investigación se llevó a cabo en una escuela media de gestión estatal ubicada en la zona centro de la ciudad de Córdoba durante el año 2009. Se trabajó con estudiantes pertenecientes a un segundo año y a un quinto año, del turno tarde. Los datos fueron recolectados a través de observaciones, entrevistas y grupos de discusión. Se usó como método de análisis, la "Teoría Fundamentada en los Datos". Desde una perspectiva psico-social y tomando los aportes de los Estudios de Género, se indagó sobre las relaciones que se construyen entre pares a nivel intergénero e intragénero. A partir del desarrollo realizado se considera que los conflictos cobran cierta especificidad cuando emergen dentro de las redes de socialidad juvenil y que habría un interjuego entre esta red y el modo en que se configuran los mismos. Asimismo en los conflictos se juegan sentidos ligados a la necesidad de obtener el reconocimiento de los pares, en la que se estarían implicando sentidos de género. Las modalidades de "saber hacer/ser" con el conflicto y eventuales episodios de violencia entre pares, brindarían recursos para la construcción de las identidades femeninas y masculinas, ancladas en significados hegemónicos de género

Pares inter pares : Controversias acerca de la traducción de Horacio en la Argentina del Siglo XIX. El caso de la Revista de derecho, historia y letras

En la Argentina, el siglo XIX -fundante en cuanto a traducción literaria- resulta también pródigo en reflexiones sobre la praxis traslativa. Entre 1899 y 1900, Matías Calandrelli instaura la polémica acerca de las versiones de Horacio y la enseñanza misma del latín en la Revista de Derecho, Historia y Letras. El análisis focaliza la valoración de la controversia como generadora de traductología, el carácter performativo de las publicaciones periódicas que operan en la construcción de un conocimiento pedagógico y disciplinar de la lengua latina, y, asimismo, la resignificación de la tradición clásica en el campo letrado

Revisión de textos en situación didáctica de intercambio entre pares

Fil: Castedo, Mirta Luisa. Universidad Nacional de La Plata. Facultad de Humanidades y Ciencias de la Educación; Argentina.

Las TIC como facilitadoras de la corrección de pares : Ensayo en Jóvenes 7

Internet está cada vez más presente en nuestras vidas y más aun en la de los adolescentes. Sumado a esto, el uso generalizado de las redes sociales ha naturalizado en ellos el compartirlo todo y recibir comentarios de pares. En la sección Jóvenes de la Escuela de Lenguas decidimos explotar esta coyuntura para la producción escrita, mediante el uso del Google Drive para así facilitar la evaluación de un ensayo de opinión entre los distintos cursos del nivel Jóvenes 7 (MCER B1+). La corrección entre compañeros tiene consecuencias de interés en el aprendizaje. Por un lado, al abandonar la concepción de docente tradicional y descentralizar la corrección, se fomenta el trabajo colaborativo y el rol activo de los alumnos, que lleva al aprendizaje significativo. Por otro lado, se empodera al alumno al permitirle usar sus conocimientos no sólo para desarrollar su propia autonomía, sino también para ayudar a los demás. Al ser percibida positivamente, esta instancia de corrección colaborativa nos parece muy prometedora a la hora de acortar la distancia entre el nivel de desarrollo efectivo de la producción escrita del alumno y su nivel de desarrollo potencial

La educación de los niños y niñas con diversidad funcional desde la perspectiva de sus pares y docentes

En este artículo se presentan las investigaciones que venimos desarrollando sobre concepciones de niñas, niños y adultos acerca de las personas con diversidad funcional. Se trata de indagaciones descriptivas y exploratorias que recogen los puntos de vista de diferentes actores en el ámbito educativo. Las conceptualizaciones sobre la diversidad funcional resultan de construcciones sociales, culturales y científicas, siendo interpretadas por los individuos como modelos que implican valoraciones, actitudes, pensamientos y prácticas hacia el colectivo "personas con discapacidades", el que se visualiza como diferente y diverso. Desde el campo de la Ética y los Derechos Humanos la consideración de la discapacidad en la educación se concentra en el tema de la igualdad y de la equiparación de oportunidades, propiciando ambientes inclusivos. Nuestras investigaciones, centradas inicialmente en niñas, niños y adolescentes, y recientemente en docentes, intentan realizar aportes y brindar insumos para la reflexión que merece este problema en el marco de la escuela como parte de una sociedad más equitativa y justa

Pares inter pares : Controversias acerca de la traducción de Horacio en la Argentina del Siglo XIX. El caso de la Revista de derecho, historia y letras

En la Argentina, el siglo XIX -fundante en cuanto a traducción literaria- resulta también pródigo en reflexiones sobre la praxis traslativa. Entre 1899 y 1900, Matías Calandrelli instaura la polémica acerca de las versiones de Horacio y la enseñanza misma del latín en la Revista de Derecho, Historia y Letras. El análisis focaliza la valoración de la controversia como generadora de traductología, el carácter performativo de las publicaciones periódicas que operan en la construcción de un conocimiento pedagógico y disciplinar de la lengua latina, y, asimismo, la resignificación de la tradición clásica en el campo letrado

Revisión de textos en situación didáctica de intercambio entre pares

Fil: Castedo, Mirta Luisa. Universidad Nacional de La Plata. Facultad de Humanidades y Ciencias de la Educación; Argentina.