956 resultados para Heterogeneidade
Resumo:
(Microarray technology in study of head neck cancer). The microarray technology is a tool for global analysis of gene expression that allows investigating hundreds or thousands of genes in a sample using a hybridization reaction. This technology is based on hybridization between labeled targets derived from biological samples and an array of many DNA probes immobilized on a solid matrix, representing the genes of interest. The simultaneous study of hundreds of genes became the microarray technique a very important tool of global analysis, with applications in several areas, including the study of the development of cancer. Head and neck squamous cell carcinoma (HNSCC) is the fifth most common cancer worldwide, with a global annual incidence of 780,000 new cases. Large-scale studies involving microarrays have identified specific gene expression signatures associated with expression changes in HNSCC samples compared to normal tissue, as well as genes involved in clinical outcome and metastasis. However, the considerable heterogeneity among these studies occurs due to experimental design, number of samples, disease sites and stage, choice of microarray platform and results validation. Thus, there is much to be validated, before the technique has clinical utility. In relation to head and neck neoplasia, the large-scale gene analysis is very important, since the clinical and histopathological methods currently used appear to be insufficient to predict clinical progression and response to treatment. Thus, this approach could result in more effective diagnostic and prognostic and most appropriate therapy for this neoplasia.
Resumo:
Artigo publicado na Eutomia: Revista Online de Literatura e Linguística Ano 3 Edição 1 Julho 2010 Seção: Destaques em Linguística.A revista é uma publicação do Departamento de Letras da UFPE.
Resumo:
Pós-graduação em Microbiologia Agropecuária - FCAV
Resumo:
Pós-graduação em Geologia Regional - IGCE
Resumo:
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Resumo:
Pós-graduação em Biopatologia Bucal - ICT
Resumo:
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Resumo:
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Resumo:
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Resumo:
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Resumo:
In this work we propose a reflection on education and, more specifically, on theprocess of teacher’s education. To approach this discussion we assume the necessityof addressing this issue in its complexity. We used the multi-referential approachthat has the perspective to study educational phenomena considering the heterogeneitytypical of educational relationships. We are holding this discussion by identifyingseveral aspects of the formation of teachers from the fields of education andpsychoanalysis. This route allowed us to deepen and clarify some concepts: education,the teaching relationship, the experienced and lived, suggesting perspectives for theprocess of teacher´s education.
Resumo:
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Resumo:
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Resumo:
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Resumo:
Pós-graduação em Zootecnia - FCAV