Henry the second /

Mode of access: Internet.

Don Phelippe, por la gracia de Dios, Rey de Castilla, de Leon, de Aragon, de las dos Sicilias ...

Verso of final leaf blank.

Norwegens Schenkung an den Heiligen Ólaf.

Aus den Abhandlungen der K. Bayer. Akademie der w., I. cl. XIV. Bd. II. Abth.

Friedrich der Grosse und sein Hof; persönliche Erinnerungen an einen 20 Jährigen Aufenthalt in Berlin.

Mode of access: Internet.

Ausgewählte Werke Friedrichs des Grossen,

Mode of access: Internet.

An account of the ceremonies observed in the coronations of the kings and queens of England : viz. King James II and his royal consort, King William III and Queen Mary, Queen Anne, King George I, and King George II and Queen Caroline.

In anticipation of the coronation of King George III.

Memoirs of Maria Antoinetta, Archduchess of Austria, Queen of France and Navarre : including several important periods of the French Revolution, from its origin to the 16th of October, 1793, the day of Her Majesty's martyrdom, with a narrative of the trial and martyrdom of Madame Elizabeth, the poisoning of Louis XVII in the temple, the liberation of Madame Royale, daughter of Louis XVI, and various subsequent events /

Vol. 2 translated by R. May ; v. 3 by Mrs. Ievers.

Shakespeare's history of King Henry the Fourth. Part II.

Mode of access: Internet.

Shakespeare's history of King Henry the Fourth : part II /

Mode of access: Internet.

Office of the City Clerk, St. Catharines Records, 1928-1974, n.d.

The site of present-day St. Catharines was settled by 3000 United Empire Loyalists at the end of the 18th century. From 1790, the settlement (then known as "The Twelve") grew as an agricultural community. St. Catharines was once referred to Shipman's Corners after Paul Shipman, owner of a tavern that was an important stagecoach transfer point. In 1815, leading businessman William Hamilton Merritt abandoned his wharf at Queenston and set up another at Shipman's Corners. He became involved in the construction and operation of several lumber and gristmills along Twelve Mile Creek. Shipman's Corners soon became the principal milling site of the eastern Niagara Peninsula. At about the same time, Merritt began to develop the salt springs that were discovered along the river which subsequently gave the village a reputation as a health resort. By this time St. Catharines was the official name of the village; the origin of the name remains obscure, but is thought to be named after Catharine Askin Robertson Hamilton, wife of the Hon. Robert Hamilton, a prominent businessman. Merritt devised a canal scheme from Lake Erie to Lake Ontario that would provide a more reliable water supply for the mills while at the same time function as a canal. He formed the Welland Canal Company, and construction took place from 1824 to 1829. The canal and the mills made St. Catharines the most important industrial centre in Niagara. By 1845, St. Catharines was incorporated as a town, with the town limits extending in 1854. Administrative and political functions were added to St. Catharines in 1862 when it became the county seat of Lincoln. In 1871, construction began on the third Welland Canal, which attracted additional population to the town. As a consequence of continual growth, the town limits were again extended. St. Catharines attained city status in 1876 with its larger population and area. Manufacturing became increasingly important in St. Catharines in the early 1900s with the abundance of hydro-electric power, and its location on important land and water routes. The large increase in population after the 1900s was mainly due to the continued industrialization and urbanization of the northern part of the city and the related expansion of business activity. The fourth Welland Canal was opened in 1932 as the third canal could no longer accommodate the larger ships. The post war years and the automobile brought great change to the urban form of St. Catharines. St. Catharines began to spread its boundaries in all directions with land being added five times during the 1950s. The Town of Merritton, Village of Port Dalhousie and Grantham Township were all incorporated as part of St. Catharines in 1961. In 1970 the Province of Ontario implemented a regional approach to deal with such issues as planning, pollution, transportation and services. As a result, Louth Township on the west side of the city was amalgamated, extending the city's boundary to Fifteen Mile Creek. With its current population of 131,989, St. Catharines has become the dominant centre of the Niagara region. Source: City of St. Catharines website http://www.stcatharines.ca/en/governin/HistoryOfTheCity.asp (January 27, 2011)

Mutation in beta1-tubulin correlates with macrothrombocytopenia in Cavalier King Charles Spaniels.

BACKGROUND Cavalier King Charles Spaniels (CKCS) have a high prevalence of inherited macrothrombocytopenia. The purpose of this study was to determine if a mutation in beta1-tubulin correlated with presumptive inherited macrothrombocytopenia. HYPOTHESIS A mutation in beta1-tubulin results in synthesis of an altered beta1-tubulin monomer. alpha-beta tubulin dimers within microtubule protofilaments are unstable, resulting in altered megakaryocyte proplatelet formation. ANIMALS Blood samples were obtained from CKCS and non-CKCS dogs. METHODS DNA was used in polymerase chain reaction (PCR) assays to evaluate beta1-tubulin. Platelet numbers and mean platelet volume (MPV) were evaluated for a correlation with the presence or absence of a mutation identified in beta1-tubulin. Platelets obtained from homozygous, heterozygous, and clear CKCS were further evaluated using electron microscopy and immunofluorescence. RESULTS A mutation in the gene encoding beta1-tubulin correlated with macrothrombocytopenia in CKCS. Electron microscopy and immunofluorescence studies suggest that platelet microtubules are present but most likely are unstable and decreased in number. CONCLUSIONS AND CLINICAL IMPORTANCE The macrothrombocytopenia of CKCS correlated with a mutation in beta1-tubulin. alpha-beta tubulin dimers within protofilaments most likely are unstable, leading to altered proplatelet formation by megakaryocytes. This information will aid in distinguishing inherited from acquired thrombocytopenia. It also provides insight into the mechanism of platelet production by megakaryocytes, and also may prove useful in understanding heart-related changes in macrothrombocytopenic CKCS with concurrent mitral valve regurgitation.

On the accession of Charles Emanuel the IVth to the throne = In occasione dell' avvenimento al trono dell' augustissimo sovrano Carlo Emmanuele IV.

Verses in English signed: Frances Negri Gobbet. Italian translation signed: Aretofilo Dianeo (?--print unclear)

The reform act, 1832; the correspondence of the late Earl Grey with His Majesty King William IV. and with Sir Herbert Taylor, from Nov. 1830 to June 1832;

Mode of access: Internet.

The poetic and dramatic works of Robert Browning.

Half-title; each volume has special t.-p.

Reminiscences of the court and times of King Ernest of Hanover /

Mode of access: Internet.