Latin Americaʹs emergence in global services: a new driver of structural change in the region?

Studies of international production acknowledge that the ability of firms to learn, upgrade and innovate in global value chains (GVCs) is influenced by knowledge flows within these global networks and by the national institutional systems in which the firms are embedded. Little is known, however, about how differences in national innovation and business systems shape the way firms and national economies insert themselves in global value chains and how this influences their upgrading trajectories. Based on a review of the existing academic literature, the chapter examines the impact of national innovation and business systems from middle-income and developing countries on learning and innovation processes in services GVCs.

Retinal ganglion cell layer change in patients treated with anti-VEGF for neovascular age related macular degeneration.

PURPOSE To evaluate macular retinal ganglion cell thickness in patients with neovascular age-related macular degeneration (AMD) and intravitreal anti-vascular endothelial growth factor (VEGF) therapy. DESIGN Retrospective case series with fellow-eye comparison METHODS: Patients with continuous unilateral anti-VEGF treatment for sub- and juxtafoveal neovascular AMD and a minimum follow-up of 24 months were included. The retinal nerve fiber (RNFL) and retinal ganglion cell layer (RGCL) in the macula were segmented using an ETDRS grid. RNFL and RGCL thickness of the outer ring of the ETDRS grid were quantified at baseline and after repeated anti-VEGF injections, and compared to the patients' untreated fellow eye. Furthermore, best-corrected visual acuity (BCVA), age, and retinal pigment epithelium (RPE) atrophy were recorded and correlated with RNFL and RGCL. RESULTS Sixty eight eyes of 34 patients (23 female and 11 male; mean age 76.7 (SD±8.2) with a mean number of 31.5 (SD ±9.8) anti-VEGF injections and a mean follow-up period of 45.3 months (SD±10.5) were included. Whereas the RGCL thickness decreased significantly compared to the non-injected fellow eye (p=0.01) the decrease of the RNFL was not significant. Visual acuity gain was significantly correlated with RGCL thickness (r=0.52, p<0.05) at follow-up and negatively correlated (r=-0.41, p<0.05) with age. Presence of RPE atrophy correlated negatively with the RGCL thickness at follow-up (r= -0.37, p=0.03). CONCLUSION During the course of long term anti-VEGF therapy there is a significant decrease of the RGCL in patients with neovascular AMD to the fellow (untreated) eye.

Great Himalaya: Tourism and the dynamics of change in Nepal

Based on extensive field work and years of personal experience, the authors discuss the development of tourism in the Great Himalaya of Nepal from the early days of mountaineering to present-day trekking. Tourism and its potentials, drawbacks, and risks are illustrated with a focus on the Khumbu/Everest and Annapurna regions, the most popular mountain destinations in the country. The themes addressed include: growth and expansion of mountain tourism; employment and income generation; wealth, poverty, and livelihood as reflected in statistics and personal accounts by local people; the revival of trade with Tibet; tourism and the role of women; the crucial role played by institutions, policies and political stability; and environmental issues such as forest degradation, garbage management, and trail damage. With its numerous illustrations, text boxes and quotes, the book is intended for a broad readership of policy- and decision-makers in tourism and development, scholars, and tourists and mountaineers who take an interest in mountain development in the Great Himalaya and elsewhere.

The proposed change in the penny : hearing before the Subcommittee on Consumer Affairs and Coinage of the Committee on Banking, Finance, and Urban Affairs, House of Reprensentatives, Ninety-seventh Congress, first session, March 31, 1981.

"Serial no. 97-4."

Workshops on technological change in the U.S. automobile industry October 1977 through April 1978 and the symposium on technology, government and the automotive future, October 19-20, 1978. Proceedings. Final report.

National Highway Traffic Safety Administration, Office of Research and Development, Washington, D.C.

Williamsburg: a Jewish community in transition; a study of the factors and patterns of change in the organization and structure of a community in transition.

The author's thesis, first issued on microfilm in 1954, now brought up to date.

Review of the U.S. Department of Agriculture's change in procedure concerning sales of commodities through the Export Credit Guarantee Program and the Intermediate Export Credit Guarantee Program [microform] : hearing before the Subcommittee on Tobacco and Peanuts of the Committee on Agriculture, House of Representatives, One Hundredth Congress, second session, October 6, 1988.

"Serial no. 100-113."

Institutes of natural philosophy, theoretical and practical. With some corrections; change in the order of the branches; and the addition of an appendix to the astronomical part, selected from Mr. Ewing's Practical astronomy.

"Appendix to the astronomy. Containing solar and lunar tables, with their explanation and use, and the projection of eclipses, selected from 'Ewing's Practical astronomy'": [233]-297.

Nonmetro job growth and locational change in manufacturing firms /

Mode of access: Internet.

Technology change in U.S. automobile industry: assessing past federal initiatives. Final report.

National Highway Traffic Safety Administration, Office of Research and Development, Washington, D.C.

Change in crew performance, physiology and affective state due to motions aboard a small monohull vessel : a preliminary study /

Final report, December 1978.

The big change in Europe.

Mode of access: Internet.

Social change in communications-oriented institutions.

Includes bibliographical references.

A Change in the Weather Service.

Shipping list no.: 89-185-P.