995 resultados para Calatayud, Melchor de-Pleitos
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Texto escrito en 1786.
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Fecha de la tasa: 1756
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Sign. : A-Q4
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Se trata de una coleccion de 12 cartas enviadas por Vicente Calatayud a Andres Piquer, que se fueron publicando separadamente y que aquí aparecen reunidas bajo una portada común. Todas están impresas por los herederos de Jeronimo Conejos, la primera carta está fechada en 1758 y la última en 1760
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Front. grab. calc. representando a San Pascual Bailón : "Joss. Camaron"
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Hay ejemplar encuadernado con XVII/1212
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Hay ejemplar encuadernado con XVII/1212
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Hay un ejemplar encuadernado con XVII/1212
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Hay un ejemplar encuadernado con XVII/1212
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Hay ejemplar encuadernado con XVII/1212
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Sing.: [A]2, B-Y2
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Hay ejemplar encuadernado con XVII/1212
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Sign.: A-G8, I7
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Orla tip. en port
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Moderate somatic stress inhibits gastric acid secretion. We have investigated the role of endogenously released NO in this phenomenon. Elevation of body temperature by 3°C or a reduction of 35 mmHg (1 mmHg = 133 Pa) in blood pressure for 10 min produced a rapid and long-lasting reduction of distension-stimulated acid secretion in the rat perfused stomach in vivo. A similar inhibitory effect on acid secretion was produced by the intracisternal (i.c.) administration of oxytocin, a peptide known to be released during stress. Intracisternal administration of the NO-synthase inhibitor, NG-nitro-l-arginine methyl ester (l-NAME) reversed the antisecretory effect induced by all these stimuli, an action prevented by intracisternal coadministration of the NO precursor, l-arginine. Furthermore, microinjection of l-NAME into the dorsal motor nucleus of the vagus nerve reversed the acid inhibitory effects of mild hyperthermia, i.v. endotoxin, or i.c. oxytocin, an action prevented by prior microinjection of l-arginine. By contrast, microinjection of l-NAME into the nucleus tractus solitarius failed to affect the inhibitory effects of hyperthermia, i.v. endotoxin, or i.c. oxytocin. Immunohistochemical techniques demonstrated that following hyperthermia there was a significant increase in immunoreactivity to neuronal NO synthase in different areas of the brain, including the dorsal motor nucleus of the vagus. Thus, our results suggest that the inhibition of gastric acid secretion, a defense mechanism during stress, is mediated by a nervous reflex involving a neuronal pathway that includes NO synthesis in the brain, specifically in the dorsal motor nucleus of the vagus.