Digital Curation Program of the Digital Public Library of America (DPLA)

The Digital Public Library of America (DPLA) is a digital library that strives to serve the public through digital collections accumulated from a wide variety of partners. Our chosen topic for the DPLA exhibit project is Perspectives on the Vietnam War. The Vietnam War remains a controversial topic of national interest, making it a topic of depth and of many perspectives. Our goals with this exhibit were to gather different perspectives of the war through personal stories, the media, presidential administrations of the war, military personnel, and the general public, including famous figures. We strove to demonstrate the variety of perspectives on the Vietnam War through a variation of digital objects and content that will be engaging for users: both black and white and color photos, videos, and audio files. Furthermore, we wanted to ensure that our digital materials are of high quality, properly documented, and easy to search and find thus all of our objects are from DPLA and are from usable original sources. This poster will describe our processes for organizational, object selection, building our exhibit, attainment of our goals, and detailed steps of our overall operation. The poster will also include details about the minor issues and bumps that occurred while reaching our final product as well as the team members’ perspectives on the project as a whole including: problems, words to for the wise, and triumphs.

Evidencia científica y recomendaciones sobre cribado de agudeza visual: revisión bibliográfica

Fundamentos: En los ámbitos científico e institucional existe controversia sobre cuándo recomendar la práctica del cribado visual en la población. El objetivo de este trabajo es valorar el nivel de evidencia científica que existe sobre el cribado visual para determinar si las recomendaciones existentes son o no adecuadas. Métodos: Revisión sistemática de artículos científicos consultando las bases de datos MedLine y The Cochranre Library Plus, sin restricción de fecha, en los idiomas español e inglés. Se incluyó literatura gris mediante búsqueda manual. No se hicieron restricciones respecto al tipo de estudio. Se revisaron los abstracts y en los casos necesarios los artículos completos, teniéndose en cuenta finalmente todos los artículos que incluían recomendaciones sobre cribado de agudeza visual y eliminando el resto. Resultados: Se seleccionaron 6 artículos. La mayoría de las recomendaciones realizadas por las sociedades fueron a través de guías de práctica clínica o artículos de opinión. Respecto a los diseños de los artículos científicos localizados hubo 2 ensayos aleatorios controlados, 3 ensayos no controlados y 1 estudio transversal. Conclusiones: Los estudios sobre adultos no permiten determinar que las recomendaciones realizadas por las sociedades científicas tengan una base científica sólida. En el caso de los niños, los estudios y las sociedades científicas no aclaran cuál es la edad más idónea para realizar cribado visual.

Alterations in energy metabolism, neuroprotection and visual signal transduction in the retina of parkinsonian, MPTP-treated monkeys

Parkinson disease is mainly characterized by the degeneration of dopaminergic neurons in the central nervous system, including the retina. Different interrelated molecular mechanisms underlying Parkinson disease-associated neuronal death have been put forward in the brain, including oxidative stress and mitochondrial dysfunction. Systemic injection of the proneurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) to monkeys elicits the appearance of a parkinsonian syndrome, including morphological and functional impairments in the retina. However, the intracellular events leading to derangement of dopaminergic and other retinal neurons in MPTP-treated animal models have not been so far investigated. Here we have used a comparative proteomics approach to identify proteins differentially expressed in the retina of MPTP-treated monkeys. Proteins were solubilized from the neural retinas of control and MPTP-treated animals, labelled separately with two different cyanine fluorophores and run pairwise on 2D DIGE gels. Out of >700 protein spots resolved and quantified, 36 were found to exhibit statistically significant differences in their expression levels, of at least ±1.4-fold, in the parkinsonian monkey retina compared with controls. Most of these spots were excised from preparative 2D gels, trypsinized and subjected to MALDI-TOF MS and LC-MS/MS analyses. Data obtained were used for protein sequence database interrogation, and 15 different proteins were successfully identified, of which 13 were underexpressed and 2 overexpressed. These proteins were involved in key cellular functional pathways such as glycolysis and mitochondrial electron transport, neuronal protection against stress and survival, and phototransduction processes. These functional categories underscore that alterations in energy metabolism, neuroprotective mechanisms and signal transduction are involved in MPTPinduced neuronal degeneration in the retina, in similarity to mechanisms thought to underlie neuronal death in the Parkinson’s diseased brain and neurodegenerative diseases of the retina proper.

Manchester, Chetham's Library MS 8009 (Mun. A.6.31): A Codicological Description

This article presents a complete codicological description of Manchester, Chetham's Library, MS 8009 (Mun.A.6.31), a late fifteenth-century production that contains a combination of secular and religious texts. The manuscript's significance for both the literary and textual scholar was recognized by Derek Pearsall when he suggested its suitability for a facsimile edition. The restrictions imposed by the Governors of the Library for reproduction under the present conditions, however, suggest that Pearsall's recommendation may have to wait for some time. The purpose of this paper is to fill that void by correcting some inaccuracies in previous descriptions and completing them with supporting visual evidence.

La adaptación de materiales docentes de marketing para estudiantes con necesidades especiales. Proyecto Speaking Library

Este trabajo presenta la experiencia docente de una Red multidisciplinar de investigadores (Red I+Do+i), en la que han participado profesorado y estudiantes. El objetivo principal de la experiencia docente “Speaking Library” es tiene una doble vertiente. Por un lado, generar documentos de trabajo especializados en investigación en docencia y en materias curriculares relevantes para el alumnado, así como en soportes más accesibles, atractivos y útiles para la comunidad educativa. Se ha tenido especial interés en los estudiantes con Necesidades Específicas de Apoyo Educativo (NEAE) y en este sentido la creación de materiales ha sido fundamentalmente audiovisual. Por otro lado, la gestión dichos materiales a través de repositorios universitarios (Universidad de Alicante y Universidad Miguel Hernández) y de un canal docente de YouTube (canal IDOi), para su ulterior difusión nacional e internacional a las distintas bases de datos y portales adecuados (OCW, blogs UA, VUALA, Blogs externos, etc.) que facilitarán su consulta. Los resultados y reflexiones finales presentan varios documentos convertidos a un formato amigable, visual y valioso para los estudiantes con NEAE, a la vez que se ha diseñado un protocolo de actuación para la elaboración de los mismos y creado un canal docente en YouTube.

General embryological information service.

v. 4 (1952)

General embryological information service.

v. 3 (1951)

General embryological information service.

v. 8 (1959)

General embryological information service.

v. 8 Suppl. (1960)

General embryological information service.

v. 1 (1949)

General embryological information service.

v. 2 (1950)

General embryological information service.

v. 9 (1961)

General embryological information service.

v. 9 Suppl. (1962)

General embryological information service.

v. 5 (1953)