988 resultados para Asparosides A And B


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As part of a larger Simplification Project for program quality assurance processes conducted at RMIT University, this paper chronicles the refinement of one aspect: program assessment and reporting. This involved the realignment of criteria used in program quality assurance with those developed in higher-level strategic and business planning processes. In addition, the project attempted to address the lack of alignment between annual program processes and subsequent decisions made about the future of programs, particularly in profile planning processes.<br />A revised Program Annual Report process was developed that aimed to achieve simplicity and alignment while re-engaging program leaders and heads of schools with the quality agenda. A concerted effort was made to develop a process that improved on previously poor vertical communication inherent in program quality assurance. This paper explores the ways in which this was achieved by a) linking people to data through the use of agreed and contextualised performance indicators, and b) linking people to process through more meaningful input into planning and opportunity for dialogue.<br />

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<b>Introduction and Aimsb>:&nbsp; This study aimed to examine: (a) the influence of family factors relative to school, peer and individual influences on the development of adolescent alcohol use during the first year of secondary school; and (b) the feasibility of preventing adolescent alcohol use by modifying family factors. <b>Design and Methodsb>:&nbsp; Twenty-four schools in Melbourne, Australia were randomly assigned to either the 'Resilient Families' intervention or a control condition. A baseline cohort of 2315 grade 7 students (mean age 12.3 years) were followed-up one year later (n = 2128 for longitudinal analyses). A sub-set of parents (n = 1166) also returned baseline surveys. <b>Resultsb>: The prevalence of lifetime alcohol use in year 7 was 33% and rose to 47% by year 8. Student-reported predictors of year 8 alcohol use included baseline alcohol [Odds Ratio (OR) 3.64] and tobacco use (2.68), and school friend's alcohol (1.41) and tobacco use (1.64). After adjusting for other influences, student-reported family factors were not maintained as significant predictors of year 8 alcohol use. Parent-report predictors of student-reported alcohol use included allowing alcohol use in the home (2.55), parental alcohol use (1.88) and child hyperactivity (1.85). Protective factors included attendance at brief parent education (0.60) and parent involvement in school education (0.65). <b>Discussion and Conclusionsb>: The intervention appeared to benefit education-related outcomes, but no overall effect in reducing student alcohol use was found in year 8. Intervention effects on alcohol misuse may become significant in later secondary school once the entire program has been implemented. Considerable alcohol use was detected in early secondary school,&nbsp;&nbsp; suggesting that interventions to reduce alcohol use may be usefully implemented prior to this period.<br />

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Television (TV) food advertising has attracted criticism for its potential role in promoting unhealthy dietary practices among children. Content analyses indicate junk food advertising is prevalent on Australian children's TV; healthy eating is rarely promoted. This paper presents (a) a cross-sectional survey examining associations between children's regular TV viewing habits and their food-related attitudes and behaviour; and (b) an experiment assessing the impact of varying combinations of TV advertisements (ads) for unhealthy and healthy foods on children's dietary knowledge, attitudes and intentions. The experimental conditions simulated possible models for regulating food ads on children's TV. Participants were 919 grade five and six students from schools in Melbourne, Australia. The survey showed that heavier TV use and more frequent commercial TV viewing were independently associated with more positive attitudes toward junk food; heavier TV use was also independently associated with higher reported junk food consumption. The experiment found that ads for nutritious foods promote selected positive attitudes and beliefs concerning these foods. Findings are discussed in light of methodological issues in media effects research and their implications for policy and practice. It is concluded that changing the food advertising environment on children's TV to one where nutritious foods are promoted and junk foods are relatively unrepresented would help to normalize and reinforce healthy eating.<br />

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Pinacolyltellurium(IV) dihalides, (t-BuCOCHb>2b>)b>2b>TeXb>2 b>(X ) Br (<b>1bb>), I (<b>1cb>)) and Ar(t-BuCOCHb>2b>)TeClb>2b> (Ar == 1-Cb>10b>Hb>7b> (Np) (<b>2ab>), 2,4,6-Meb>3b>Cb>6b>Hb>2b> (Mes) (<b>3ab>)), are readily prepared at room temperature by the oxidative insertion of elemental tellurium into the Cb>spb>3-Br or -I bond of the &alpha;-halopinacolone and by the reaction of ArTeClb>3b> with the pinacolone t-BuCOCHb>3b>. The bromides Np(t-BuCOCHb>2b>)TeBrb>2b> (<b>2bb>) and Mes(t-BuCOCHb>2b>)TeBrb>2b> (<b>3bb>) can be prepared by the addition of bromine to the telluride Ar(t-BuCOCHb>2b>)-Te or of &alpha;-bromopinacolone to ArTeBr. Variable-temperature 1H and 13C NMR of the separate signals for the o-Me groups in <b>3ab>,<b>bb> indicate a very high barrier to rotation about the Te-C(aryl) bond. Crystal diffraction data for <b>1cb>, <b>2a-cb>, and <b>3bb> show that intramolecular 1,4-Te …O(C) secondary bonding interactions (SBIs) are retained even in the presence of bulky aryl groups and intermolecular Te …X SBIs are subject to electronic population and steric congestion around the Te(IV) center in the solid state.<br />

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This chapter uses the case of students enrolled in the Multimedia Pathway offered by Harbourside High School to discuss the tensions and contradictions inherent in the views that: (a) school curriculum and pedagogy have much to learn from young people's informal and leisure-based learning; and (b) school-based courses in new media are important because they increase student retention and the chance of success in post-school employment. We draw on literature about the "new work order" (Gee, Hull, &amp; Lankshear, 1996) to explore the nature of these students' learning about and with lCTs and show that the students' knowledge exists "in a network of relationships" (Gee, 2000) that bridge the formal and informal learning divide. Finally, we discuss the parts played by their in- and out-oi-school engagements with lCT in their becoming the kinds of portfolio people supposedly required by the new capitalism.<br />

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The complexes [Hpy][Cu(Hb>3b>L)(H2O)] <b>1b> (L6 = nitrilotrimethylenetrisphosphonate) and [Cu(HL°)(py)]b>2b>·2Meb>2b>CO <b>2b> [(L°)3 = P,P,P" -triphenylnitrilotrismethylenetrisphosphinate)] have been isolated and characterized by X-ray crystallography, near IR-visible spectroscopy and magnetic measurements. The structure determination has shown the complexes to be constituted by monomeric and dimeric units respectively. In the monomer the metal atom is surrounded by the phosphonate ligand and a water molecule, with a geometry between a trigonal bipyramid and a square pyramid. The two copper atoms in the dimer are held together by an arm of the tripod ligand, with a pyridine molecule as additional ligand, and display octahedral geometry. The presence of monomeric and dimeric species in aqueous solutions of <b>1b> and <b>2b> has been shown by ESMS studies. The formation in water solution of the dimer [{Cu(Hb>3b>L)}b>2b>]2-, as a minor species, has been supported by potentiometric measurements, whereas only the monomeric anion [CuL°] has been ascertained to be present. In general the ligand Hb>3b>L° forms less stable copper(II) complexes than Hb>6b>L.<br /><br /><br />

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The synthesis and characterization by multinuclear NMR spectroscopy of the diorganotin dihalides (Meb>3b>SiCHb>2b>)b>2b>SnXb>2b> (<b>1b>, X = Cl; <b>2b>, X = Br), the diorganotin dichloride water adduct (Meb>3b>SiCHb>2b>)b>2b>SnClb>2b>·Hb>2b>O (<b>1ab>), the dimeric tetraorganodistannoxanes [(Meb>3b>SiCHb>2b>)b>2b>(X)SnOSn(Y)(CHb>2b>SiMeb>3b>)b>2b>]b>2b> (<b>3b>, X = Y = Cl; <b>4b>, X = Br, Y = OH; <b>5b>, X = Br, Y = F; <b>6b>, X = Y = OH; <b>8b>, X = Cl, Y = OH), and the molecular diorganotin oxide cyclo-[(Meb>3b>SiCHb>2b>)b>2b>SnO]b>3b> (<b>7b>) are reported. The structures in the solid state of compounds <b>1a, 3, 6,b> and <b>7b> were determined by single-crystal X-ray analysis. In toluene solution, the hydroxy-substituted tetraorganodistannoxane <b>6b> is in equilibrium with the diorganotin oxide <b>7b> and water. The eight-membered diorganotin oxide cyclo-[(Meb>3b>SiCHb>2b>)b>2b>SnO]b>4b> (<b>7ab>) is proposed to be involved in this equilibrium. On the basis of the results of this and previous works, a general hydrolysis pathway is developed for diorganotin dichlorides containing reasonably bulky substituents.<br />

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Reaction of the dimethylsilylmethyl-substituted tetraorganotin derivative CHb>2b>[CHb>2b>Sn(Phb>2b>)CHb>2b>Si(H)Meb>2b>]b>2b> (<b>1b>) and CHb>2b>[CHb>2b>Sn(Phb>2b>)CHb>2b>Si(i-PrO)Meb>2b>]b>2b> (<b>3b>), respectively, with mercuric chloride afforded the novel silicon- and tin-containing 10- and 20-membered rings cyclo-CHb>2b>[CHb>2b>Sn(Clb>2b>)CHb>2b>Si(Meb>2b>)]b>2b>O (<b>4b>) and cyclo-CHb>2b>[CHb>2b>Sn(Clb>2b>)CHb>2b>Si(Meb>2b>)OSi(Meb>2b>)CHb>2b>Sn(Clb>2b>)CHb>2b>]b>2b>CHb>2b> (<b>5b>). Both compounds <b>4b> and <b>5b> can be converted into the soluble Lewis acidic polymer poly-[Si(Meb>2b>)CHb>2b>Sn(Clb>2b>)(CHb>2b>)b>3b>Sn(Clb>2b>)CHb>2b>Si(Meb>2b>)O] (<b>8b>). 119Sn NMR studies indicate that <b>4b> acts as a bidentate Lewis acid toward chloride ions, exclusively forming the 1:1 complex [cyclo-CHb>2b>[CHb>2b>Sn(Clb>2b>)CHb>2b>Si(Meb>2b>)]b>2b>O·Cl]-[(Phb>3b>P)b>2b>N]+ (<b>7b>). The molecular structures as determined by single-crystal X-ray diffraction analysis of <b>4b> and <b>7b> are reported. <br />

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The reaction of (p-MeOCb>6b>Hb>4b>)b>2b>TeO with two equivalents of HOb>3b>SCFb>3b> and HOb>2b>PPhb>2b> provided the tetraorganoditelluroxanes (Fb>3b>CSOb>3b>)(p-MeOCb>6b>Hb>4b>)b>2b>TeOTe(p-MeOCb>6b>Hb>4b>)b>2b>(Ob>3b>SCFb>3b>) (<b>1b>) and (Phb>2b>POb>2b>)(p-MeOCb>6b>Hb>4b>)b>2b>TeOTe(p-MeOCb>6b>Hb>4b>)b>2b>(Ob>2b>PPhb>2b>)·2 Phb>2b>POb>2b>H (<b>2b>) in good yields. Compounds <b>1b> and <b>2b> were characterized by solution and solid-state 31P and 125Te NMR spectroscopy, IR spectroscopy, electrospray mass spectrometry, conductivity measurements and single crystal X-ray diffraction. In solution, compound <b>1b> undergoes an electrolytic dissociation and reversibly reacts with traces of water to give the mononuclear cation [(p-MeOCb>6b>Hb>4b>)b>2b>TeOH]+ and triflate anions. Theoretical aspects of the protonation and hydration of model telluroxanes Rb>2b>TeO (R = H, Me, Ph) were investigated by preliminary DFT calculations and compared to the corresponding selenoxanes Rb>2b>SeO. The tellurium dihydroxides Rb>2b>Te(OH)b>2b> seem to be more stable than the hydrogen-bonded complexes Rb>2b>TeO·Hb>2b>O.<br />

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The unsymmetrical1y substituted diorganotellurium dihalides [2-(4,4'-N0b>2b>Cb>6b>Hb>4b>CHNCb>6b>Hb>3b>Me]RTeXb>2b> (R = 4-MeOCb>6b>Hb>4b>, X = Cl,<br /><b>1ab>; Br, <b>1bb>; I, <b>1cb>; R =4-MeCb>6b>Hb>4b> ; X = Cl, <b>2b>; R =Cb>6b>Hb>5b>, X = Cl, 3) were prepared in good yields and characterized by solution and solid-state 125Te NMR spectroscopy, IR spectroscopy and X-ray crystallography. In the solid-state, molecular structures of <b>1ab> and <b>1cb> possess scarcely observed 1,4-type intramolecular Te···N secondary interaction. Crystal packing of these compounds show an unusually rich diversity of intermolecular secondary, Te·· ·0, Te· .. \ and 1···1 interactions, Te·· ·π contacts as well as extensive<br />π-stacking of the organic substituents.<br />

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The synthesis and characterization of unsymmetric diorganotellurium compounds containing a sterically demanding I-naphthyl or<br />mesitylligand and a small bite chelating organic ligand capable of 1,4-Te···N(O) intramolecular interaction is described. The reaction<br />of ArTeClb>3b> (Ar = I-Cb>lOb>Hb>7b>, Np; 2,4,6-Meb>3b>Cb>6b>Hb>2'b> Mes) with (SB)HgCI [SB = the Schiff base, 2-(4,4'-N0b>2b>Cb>6b>Hb>4b>CH=NCb>6b>Hb>3b>-Me)] or a methyl ketone (RCOCHb>3b>) afforded the corresponding dichlorides (SB)ArTeCIb>2b> (Ar = Np, <b>1Aab>; Mes, <b>1Bab>) or (RCOCHb>2b>)ArTeClb>2b> (Ar = Np; R = Ph (<b>2Aab>), Me (<b>3Aab>), Np (<b>4Aab>); Ar = Mes, R = Ph (<b>2Bab>)). Reduction of <b>1Aab> and <b>1Bab> by Nab>2b>Sb>2b>0b>5b> readily gave the tellurides (SB)ArTe (Ar = Np (<b>1Ab>), Mes, (<b>1Bb>) but that of dichlorides derived from methylketones was complicated due to partial decomposition to tellurium powder and diarylditelluride (Arb>2b>Teb>2b>), resulting in poor yields of the corresponding tellurides <b>2Ab>, <b>2Bb> and <b>3Ab>. Oxidation of the isolated tellurides with S0b>2b>Clb>2b>, Brb>2b> and Ib>2b> yielded the corresponding dihalides. All the synthesized compounds have been characterized with the help of IR, 1H, l3C, and 125Te NMR and in the case of <b>2Aab>, and <b>2Bab> by X-ray crystallography. Appearance of only one 125Te signal indicated that the unsymmetric derivatives were stable to disproportionation to symmetric species. Intramolecular 1,4-Te· . ·0 secondary bonding interactions (SBIs) are exhibited in the crystal structures of both the tellurium(IV) dichlorides, <b>2Aab>, and <b>2Bab>. Steric repulsion of the mesityl group in the latter dominates over lone pair-bond pair repulsion, resulting in significant widening of the equatorial C-Te-C angle. This appears to be responsible for the lack of Te· . ·CI involved supramolecular associations in the crystal structure of <b>2Bab>.<br />

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Monomeric tellurides 4-RCb>6b>Hb>4b>(SB)Te [SB = 2-(4,4'-N0b>2b>Cb>6b>Hb>4b>CH=NCb>6b>Hb>3b>-Me); R = H, an style="font-weight: bold;">1an><b>ab>; Me,an style="font-weight: bold;">1an><b>bb>; OMe, an style="font-weight: bold;">1an><b>cb>], which incidentally represent the first example of a telluride with 1,4-Te···N intramolecular interaction, have been prepared and characterized by solution and solid-state 125Te NMR, 13C NMR and X-ray crystallography. Interplay of weak C-H···O and C-H-··π{ interactions in the crystal lattice of an style="font-weight: bold;">1an><b>bb> andan style="font-weight: bold;">1an><b>cb> are responsible for the formation of supramolecular motifs. These tellurides undergo expected oxidative addition reactions with halogens and interhalogens and also interact coordinatively with mercury(II) halides to give 1:2 complexes, HgXb>2b>[4-RCb>6b>Hb>4b>(SB)Te]b>2b> (X = CI, R = H, <b>2ab>; Me, <b>2bb>; OMe, <b>2cb> and X = Br, R = H, <b>3ab>; Me, <b>3bb>; and OMe, <b>3cb>) with no sign of Te-C bond cleavage, as has been reported for some 1,5-Te·· ·N(O) intramolecularly bonded tellurides. The complexes <b>2ab> and <b>3cb> are the first structurally characterized monomeric 1:2 adducts of mercury(II) halides with Te ligands. The 1,4-Te···N intramolecular interactions in the solid-state are retained in the complexes highlighting simultaneously the Lewis acid and base character of the Te(lI) atom. Packing of molecules in the crystal lattice of <b>2ab><br />and <b>3c b>reveals that non-covalent C-H· . ·Cl/Br interactions involving metal-bound halogen atoms possess significant directionality and in<br />combination with coordinative covalent interactions may be of potential use in creating inorganic supramolecular synthons.<br />

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<b>Objectiveb>: To identify and address particular challenges in the teaching of epidemiological concepts to undergraduate students in non-clinical health disciplines. <b>Methods and Resultsb>: Relevant pedagogical literature was reviewed to identify a range of evidence-based teaching approaches. The authors also drew on their experience in curriculum development and teaching in this field to provide guidelines for teaching epidemiology in a way that is engaging to students and likely to promote deep, rather than surface, learning. Discussion of a range of practical strategies is included along with applied examples of teaching epidemiological content. <b>Conclusions andb> <b>Implicationsb>: Increasingly, there is a greater emphasis on improved learning outcomes in higher education. Graduates from non-clinical health courses are required to have a core understanding of epidemiology and teachers of epidemiology need to be able to access resources that are relevant and useful for these students. A theoretically grounded framework for effective teaching of epidemiological principles to non-clinical undergraduates is provided, together with a range of useful teaching resources (both paper and web-based). Implementation of the strategies discussed will help ensure graduates are able to appropriately apply epidemiological skills in their professional practice.<br />

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The concept of market orientation has received a great deal of attention from marketing scholars, indicating its conceptual and practical importance. The concept has been investigated from many perspectives and examined in many ways. The current general understanding is that market orientation, in most cases, is positively related to some measures of organisational performance and that different internal and external situations moderate this relationship. This paper aims to (1) introduce a measure of market orientation effectiveness, which represents a synthesis of the influence of different internal and external moderators on market orientation, and (2) measure the association of market orientation effectiveness with (a) a marketing performance outcome and (b) the overall organisational financial performance. The results from a survey of 216 large Australian businesses indicated that some variables (an organisation’s strategy of cost leadership, market strength, implementation effectiveness, and market volatility) have positive contributions at different degrees to market orientation effectiveness, while anticipated competitive reaction contributes negatively. Results also indicated that in the sample studied, both market orientation and market orientation effectiveness were more strongly associated with a measure of marketing performance, than with the overall financial performance, which is a function of both marketing and non-marketing initiatives.<br />

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Throughout the world, many native species inhabit agricultural landscapes. While natural habitats will form the cornerstone of conservation efforts in production-oriented environments, the success of these efforts will be enhanced by a greater understanding of the potential contribution of the increasingly modified countryside (‘matrix’) elements in these landscapes. Here, we investigate the relative occurrence of birds in some landscape elements (i.e. land-uses, vegetation types) common to agricultural environments around the world. Twenty-seven study mosaics (1 km × 1 km in size), selected to incorporate variation in the cover of native vegetation and the richness of different landscape elements, were sampled in Gippsland, south-eastern Australia. Birds were surveyed in five main types of elements: native vegetation, linear vegetation, plantation, scattered trees and pasture. The greatest number of species was recorded in native vegetation, the most important element for the majority of birds in Australian agricultural landscapes. Nevertheless, most countryside elements had value for many species; particularly structurally complex elements. Ordination analyses (based on presence/absence data for 81 species) showed that the composition of bird communities differed between elements. The number of mosaics in which ‘all species’ and ‘woodland species’ were recorded was positively related to the breadth of elements they used; thus species using a greater number of elements occurred more frequently in the study region. Correlation analyses identified that the richness of woodland species (those of increased conservation concern in Australia) in different elements was influenced by features of the mosaic in which they occurred. Notably, the richness of woodland bird species recorded in scattered trees and pasture increased with local native vegetation cover. Key implications for conservation in Australian agricultural environments include: (1) native vegetation is vital for the persistence of birds in these landscapes, and thus is the primary element on which conservation efforts in agricultural landscapes depend; (2) countryside elements can enhance the conservation value of agricultural landscapes by (a) increasing structural complexity in largely cleared areas and (b) increasing the heterogeneity of the entire landscape; and (3) patches of different elements cannot be managed in isolation from their surroundings, as landscape properties affect the richness of bird assemblages in different elements.<br />