1000 resultados para 183-1138


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El pejerrey es pescado desde el Puerto Pizarro hasta la frontera con Chile, los mayores desembarques se reportaron para la zona central del Perú y en los meses más fríos del año. Durante fenómenos El Niño los desembarques bajaron, especialmente en el de 1982-183.

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En mayo de 187 un total de 71 marisqueros de cuatro caletas en la zona de Atico fueron entrevistados sobre diferentes aspectos de su vida y trabajo. Las especies explotadas más importantes son los gastrópodos Concholepas concholepas y Thais chocalata.

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OBJECTIVE: Macrophages play a critical role in intestinal wound repair. However, the molecular pathways that regulate macrophage wound repair activities remain poorly understood. The aim of this study was to evaluate the role of GM-CSF receptor signaling in the wound repair activities of macrophages. METHODS: Murine macrophages were differentiated from bone marrow cells and human macrophages from monocytes isolated from peripheral blood mononuclear cells of Crohn's disease (CD) patients. In vitro models were used to study the repair activities of macrophages. RESULTS: We provide evidence that GM-CSF receptor signaling is required for murine macrophages to promote epithelial repair. In addition, we demonstrate that the deficient repair properties of macrophages from CD patients with active disease can be recovered via GM-CSF therapy. CONCLUSION: Our data support a critical role of the GM-CSF signaling pathway in the pro-repair activities of mouse and human macrophages. © 2014 S. Karger AG, Basel.

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Large, rare copy number variants (CNVs) have been implicated in a variety of psychiatric disorders, but the role of CNVs in recurrent depression is unclear. We performed a genome-wide analysis of large, rare CNVs in 3106 cases of recurrent depression, 459 controls screened for lifetime-absence of psychiatric disorder and 5619 unscreened controls from phase 2 of the Wellcome Trust Case Control Consortium (WTCCC2). We compared the frequency of cases with CNVs against the frequency observed in each control group, analysing CNVs over the whole genome, genic, intergenic, intronic and exonic regions. We found that deletion CNVs were associated with recurrent depression, whereas duplications were not. The effect was significant when comparing cases with WTCCC2 controls (P=7.7 × 10(-6), odds ratio (OR) =1.25 (95% confidence interval (CI) 1.13-1.37)) and to screened controls (P=5.6 × 10(-4), OR=1.52 (95% CI 1.20-1.93). Further analysis showed that CNVs deleting protein coding regions were largely responsible for the association. Within an analysis of regions previously implicated in schizophrenia, we found an overall enrichment of CNVs in our cases when compared with screened controls (P=0.019). We observe an ordered increase of samples with deletion CNVs, with the lowest proportion seen in screened controls, the next highest in unscreened controls and the highest in cases. This may suggest that the absence of deletion CNVs, especially in genes, is associated with resilience to recurrent depression.

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A evolução actual do ensino superior mostra claramente a importância crescente das formações ao nível de pós-graduação. Observamos também a proliferação de programas cada vez mais especializados e formatados para públicos exigentes. A preocupação com a qualidade dos serviços oferecidos contribui também para um maior interesse pela formação que permita acompanhar as novas tendências em diferentes áreas de conhecimento. O desenvolvimento rápido e disperso dos meios de comunicação resultou no aumento de trabalhadores nesta área. Não obstante, no caso de Cabo Verde, só alguns detêm a formação universitária adequada. O curso pretende, de alguma maneira, oferecer aos profissionais de comunicação e informação, a possibilidade de completar a experiência com conhecimentos específicos e actuais.

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Ancien possesseur : Argenson, Antoine-René de Voyer (1722-1787 ; marquis de Paulmy d')

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Expone que el control de la calidad alimentaria presenta tres aspectos: físico-organoleótico, microbiológico y químico, cada cual con su metodología propia. Las especies destinadas al consumo humano requieren una calidad satisfactoria con el fin de garantizar sus cualidades nutricionales y sanitarias, por lo que es importante efectuar controles cualitativos de estos productos.

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Kirje

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A high-resolution three-dimensional (3D) seismic reflection system for small-scale targets in lacustrine settings has been developed. Its main characteristics include navigation and shot-triggering software that fires the seismic source at regular distance intervals (max. error of 0.25 m) with real-time control on navigation using differential GPS (Global Positioning System). Receiver positions are accurately calculated (error < 0.20 m) with the aid of GPS antennas attached to the end of each of three 24-channel streamers. Two telescopic booms hold the streamers at a distance of 7.5 m from each other. With a receiver spacing of 2.5 m, the bin dimension is 1.25 m in inline and 3.75 m in crossline direction. To test the system, we conducted a 3D survey of about 1 km(2) in Lake Geneva, Switzerland, over a complex fault zone. A 5-m shot spacing resulted in a nominal fold of 6. A double-chamber bubble-cancelling 15/15 in(3) air gun (40-650 Hz) operated at 80 bars and 1 m depth gave a signal penetration of 300 m below water bottom and a best vertical resolution of 1.1 m. Processing followed a conventional scheme, but had to be adapted to the high sampling rates, and our unconventional navigation data needed conversion to industry standards. The high-quality data enabled us to construct maps of seismic horizons and fault surfaces in three dimensions. The system proves to be well adapted to investigate complex structures by providing non-aliased images of reflectors with dips up to 30 degrees.

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Kirje

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Este crucero se desarrolló entre el 20 de mayo al 18 de junio 2003, de Puerto Pizarro a Huarmey, hasta 80 mn de la costa. Se relacionan las condiciones hidroquímicas con los recursos demersales, enfatizando en los niveles de oxigenación. Las observaciones más importantes fueron: (1) La Extensión Sur de la Corriente de Cromwell se localizó al norte de 9°S, frente a Punta Chao. (2) Los promedios de oxígeno disuelto registrados en las secciones verticales a los 100 m fueron: 1,74 mL/L en Puerto Pizarro; 1,55 mL/L en Paita; 1,29 mL/L en Punta Falsa; 0,69 mL/L en Chicama y 0,27 mL/L en Chimbote. (3) En la columna de agua, las concentraciones de oxígeno de 0,45 a 2,18 mL/L se encontraron asociadas a los siguientes rangos de nutrientes: fosfatos, 1,43–2,39 uM; silicatos 12,26–24,97 uM; nitratos, 16,13–25,70 uM. (4) El afloramiento fue más intenso frente a Chicama, cuyos valores en superficie fueron: oxígeno 1,40 mL/L; temperatura 15,4 °C; fosfatos 2,63 μM; silicatos 24,33 μM; nitratos 13,72 μM.