Safety of falciparum malaria diagnostic strategy based on rapid diagnostic tests in returning travellers and migrants: a retrospective study.

BACKGROUND: Rapid diagnostic tests for malaria (RDTs) allow accurate diagnosis and prompt treatment. Validation of their usefulness in travellers with fever was needed. The safety of a strategy to diagnose falciparum malaria based on RDT followed by immediate or delayed microscopy reading at first attendance was evaluated in one referral hospital in Switzerland. METHODS: A retrospective study was conducted in the outpatient clinic and emergency ward of University Hospital, covering a period of eight years (1999-2007). The study was conducted in the outpatient clinic and emergency ward of University Hospital. All adults suspected of malaria with a diagnostic test performed were included. RDT and microscopy as immediate tests were performed during working hours, and RDT as immediate test and delayed microscopy reading out of laboratory working hours. The main outcome measure was occurrence of specific complications in RDT negative and RDT positive adults. RESULTS: 2,139 patients were recruited. 1987 had both initial RDT and blood smear (BS) result negative. Among those, 2/1987 (0.1%) developed uncomplicated malaria with both RDT and BS positive on day 1 and day 6 respectively. Among the 152 patients initially malaria positive, 137 had both RDT and BS positive, four only BS positive and five only RDT positive (PCR confirmed) (six had only one test performed). None of the four initially RDT negative/BS positive and none of the five initially BS negative/RDT positive developed severe malaria while 6/137 of both RDT and BS positive did so. The use of RDT allowed a reduction of a median of 2.1 hours to get a first malaria test result. CONCLUSIONS: A malaria diagnostic strategy based on RDTs and a delayed BS is safe in non-immune populations, and shortens the time to first malaria test result.

Desenvolupament d'una aplicació per l'Eye Tracker

El treball consisteix en realitzar una aplicació que faci ús de l'Eye Tracker. L'objectiu marcat es realitzar una aplicació que permeti escriure coses a l'ordinador a persones discapacitades fent ús del dispositiu "Eye Tracker". Aquesta aplicació intentarà facilitar les coses a les persones discapacitades pel que fa a l'ús de l'ordinador i s'intentarà que l'aplicació acabi amb una de les limitacions més importants en persones que no poden fer ús de les mans, i per tant, no poden escriure en l'ordinador.

Assessing rapid evolution in a changing environment.

Climate change poses a serious threat to species persistence. Effective modelling of evolutionary responses to rapid climate change is therefore essential. In this review we examine recent advances in phylogenetic comparative methods, techniques normally used to study adaptation over long periods, which allow them to be applied to the study of adaptation over shorter time scales. This increased applicability is largely due to the emergence of more flexible models of character evolution and the parallel development of molecular technologies that can be used to assess adaptive variation at loci scattered across the genome. The merging of phylogenetic and population genetic approaches to the study of adaptation has significant potential to advance our understanding of rapid responses to environmental change.

E-1 Monthly Statistical Movement Summary for Entire Iowa Department of Corrections, Iowa Department of Corrections, February 2001

Monthly Statistical Movement Summary for Entire Iowa Department of Corrections

E-1 Monthly Statistical Movement Summary for Entire Iowa Department of Corrections, Iowa Department of Corrections, May 2001

Monthly Statistical Movement Summary for Entire Iowa Department of Corrections

E-1 Monthly Statistical Movement Summary for Entire Iowa Department of Corrections, Iowa Department of Corrections, April 2001

Monthly Statistical Movement Summary for Entire Iowa Department of Corrections

E-1 Monthly Statistical Movement Summary for Entire Iowa Department of Corrections, Iowa Department of Corrections, May 2001

Monthly Statistical Movement Summary for Entire Iowa Department of Corrections

E-1 Monthly Statistical Movement Summary for Entire Iowa Department of Corrections, Iowa Department of Corrections, June 2001

Monthly Statistical Movement Summary for Entire Iowa Department of Corrections

E-1 Monthly Statistical Movement Summary for Entire Iowa Department of Corrections, Iowa Department of Corrections, July 2001

Monthly Statistical Movement Summary for Entire Iowa Department of Corrections

E-1 Monthly Statistical Movement Summary for Entire Iowa Department of Corrections, August 2001

Monthly Statistical Movement Summary for Entire Iowa Department of Corrections

E-1 Monthly Statistical Movement Summary for Entire Iowa Department of Corrections, September 2001

Monthly Statistical Movement Summary for Entire Iowa Department of Corrections

E-1 Monthly Statistical Movement Summary for Entire Iowa Department of Corrections, Iowa Department of Corrections, November 2001

Monthly Statistical Movement Summary for Entire Iowa Department of Corrections

E-1 Monthly Statistical Movement Summary for Entire Iowa Department of Corrections, Iowa Department of Corrections, November "A" 2001

Monthly Statistical Movement Summary for Entire Iowa Department of Corrections

E-1 Monthly Statistical Movement Summary for Entire Iowa Department of Corrections, Iowa Department of Corrections, December 2001

Monthly Statistical Movement Summary for Entire Iowa Department of Corrections