Design de superfície - abordagem qualitativa para fachadas corporativas

This paper reports the stage of a research on the corporate identity in commercial buildings. The objective of the research is to develop a system that aims to help the designer to enhance the transmission of the brand identity on the construction. At this step, we looked for the ascertainment of the variables that contribute to it in buildings considered as icons of brand identification in the building. And this paper also presents an analysis of a flagship located in Tokyo, from the Dior brand, which we used Surface Design techniques, combining cultural studies to geometric modeling, to Gestalt and Semiotics.

O uso do bambu laminado colado na confecção de mobiliário

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Infecção viral respiratória comunitária e hospitalar em pacientes submetidos a transplante de células tronco hematopoiéticas

Pós-graduação em Pesquisa e Desenvolvimento (Biotecnologia Médica) - FMB

Licenciamento provisório da patente: inibidores de protease no tratamento da Hepatite C crônica

Pós-graduação em Pesquisa e Desenvolvimento (Biotecnologia Médica) - FMB

Estudo das alterações genéticas da Interleucina 28B em Astrocitomas

Pós-graduação em Pesquisa e Desenvolvimento (Biotecnologia Médica) - FMB

Perfil de mutações e resistência do Vírus da Imunodeficiência Humana (HIV) em pacientes coinfectados com o Vírus da Hepatite B (VHB)

Pós-graduação em Pesquisa e Desenvolvimento (Biotecnologia Médica) - FMB

Análise multivariada das atividades científicas e técnicas no processo de adoção de inovação em empresas sucroenergéticas do centro-oeste do estado de São Paulo

The primary objective of this study was to verify the existence of internal organization and processes influencing the decisions on adoption, choice, justification and implementation of innovative practices of scientific and technical activities undertaken in the elaborates of sugar, ethanol and energy companies of the midwest of the state of Sao Paulo. Using multivariate analysis of principal components and clusters, the variables were analyzed and the companies, classified. The taxonomy model adapted to contemporary situations described by Freeman (1975), was the 'parameter used with research information in personal interviews by semi-structured questionnaires. The investigated activities constituted of: basic research; applied research; experimental development; scientific and technical information; long-term planning. The variables analyzed were: production processes, operating systems, development of new products, projects and implementation of pilot plant for new products, development, knowledge, studies of other business segments, number of innovations, and the number of existing employees in the organizational structure for these purposes. It was concluded that the best companies with innovative attitudes are those that have incorporated into their organizational the structures, practices and techniques of scientific activities.

Aloimunização de doadores de sangue como fonte de anti-soros e hemácias raras

Pós-graduação em Pesquisa e Desenvolvimento (Biotecnologia Médica) - FMB

Análise da pressão intra-abdominal em pacientes submetidos à cirurgia abdominal oncológica internados em Unidade de Terapia Intensiva

Pós-graduação em Pesquisa e Desenvolvimento (Biotecnologia Médica) - FMB

Interação entre Citocinas, Plaquetas e Fibrogênese na Investigação da Metaplasia Mielóide Hepática

Pós-graduação em Pesquisa e Desenvolvimento (Biotecnologia Médica) - FMB

Avaliação da infecção de megacariócitos e plaquetas pelo VHC e sua influência na fisiopatologia da hepatite C

Pós-graduação em Pesquisa e Desenvolvimento (Biotecnologia Médica) - FMB

Bioestimulação de célula-tronco mesenquimal de rato sob ação da luz contínua e pulsátil de 630 nm utilizando LED

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Bioestimulação de célula-tronco mesenquimal de rato sob ação da luz contínua e pulsátil de 630 nm utilizando LED

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Anti-Atherogenic Effects of a Phenol-Rich Fraction from Brazilian Red Wine (Vitis labrusca L.) in Hypercholesterolemic Low-Density Lipoprotein Receptor Knockout Mice

Moderate wine intake (i.e., 1-2 glasses of wine a day) is associated with a reduced risk of morbidity and mortality from cardiovascular disease. The aim of this study was to evaluate the anti-atherosclerotic effects of a nonalcoholic ethyl acetate fraction (EAF) from a South Brazilian red wine obtained from Vitis labrusca grapes. Experiments were carried out on low-density lipoprotein (LDL) receptor knockout (LDLr-/-) mice, which were subjected to a hypercholesterolemic diet and treated with doses of EAF (3, 10, and 30 mg/kg) for 12 weeks. At the end of the treatment, the level of plasma lipids, the vascular reactivity, and the atherosclerotic lesions were evaluated. Our results demonstrated that the treatment with EAF at 3 mg/kg significantly decreased total cholesterol, triglycerides, and LDL plus very low-density lipoprotein levels compared with control hypercholesterolemic mice. The treatment of mice with EAF at 3 mg/kg also preserved the vasodilatation induced by acetylcholine on isolated thoracic aorta from hypercholesterolemic LDLr-/- mice. This result is in agreement with the degree of lipid deposit on arteries. Taken together, the results show for the first time that the lowest concentration of an EAF obtained from a red wine produced in southern Brazil significantly reduced the progression of atherosclerosis in mice.

Short-term creatine supplementation decreases reactive oxygen species content with no changes in expression and activity of antioxidant enzymes in skeletal muscle

The effect of short-term creatine (Cr) supplementation upon content of skeletal muscle-derived-reactive oxygen species (ROS) was investigated. Wistar rats were supplemented with Cr (5 g/kg BW) or vehicle, by gavage, for 6 days. Soleus and extensor digitorum longus (EDL) muscles were removed and incubated for evaluation of ROS content using Amplex-UltraRed reagent. The analysis of expression and activity of antioxidant enzymes (superoxide dismutase 1 and 2, catalase and glutathione peroxidase) were performed. Direct scavenger action of Cr on superoxide radical and hydrogen peroxide was also investigated. Short-term Cr supplementation attenuated ROS content in both soleus and EDL muscles (by 41 and 33.7%, respectively). Cr supplementation did not change expression and activity of antioxidant enzymes. Basal TBARS content was not altered by Cr supplementation. In cell-free experiments, Cr showed a scavenger effect on superoxide radical in concentrations of 20 and 40 mM, but not on hydrogen peroxide. These results indicate that Cr supplementation decreases ROS content in skeletal muscle possibly due to a direct action of Cr molecule on superoxide radical.