La carcajada : drama en tres actos y en prosa ...[y otras obras]

Mode of access: Internet.

Zelo imitado de Elias, por la ley, y por el honor de Dios, y de su antiguo pueblo : instruccion del pueblo christiano en la primacia de las substancia de la Fè, y la ley de Iesu-Christo ... : obra vtil para los professores de todas las quatro theologias, y en especial para los predicadores euangelicos ... /

Mode of access: Internet.

Incipit artium cursus : Et primo, quas sumulas dicunt, institutiones ex Aristotelicis libris de promptae, iuxta mentem N. Resoluti doctoris, & ad formam isagogicam redactae /

Texto a dos columnas.

[De los deberes del medico en sus relaciones profesionales con la mujer] : Discurso leido en la Universidad Central /

Mode of access: Internet.

El Orinoco ilustrado y defendido: historia natural, civil y geographica de este gran rio y de sus caudalosas vertientes, govierno, usos y costumbres de los indios sus habitadores ... /

Mención de edición precede a edición de parte. Error de paginación : de p. 144 pasa a p. 149.

Commentaria in Aristotelis logicam : juxta mentem et doctrinam ... Joannis Bachoni /

Mode of access: Internet.

Roma antica /

Frontispiece port. of Nardini, v. 1, by L. Carlini. Illustrations new to this edition engraved by G. Acquaroni, G. Balzar, Giuseppe Mochetti and Angelo Testa, after drawings by Antonio de Romanis, Francesco Piranesi, Rosino, Angelo Uggeri, Giovanni Battista Vergani. Plates depicting coins by Carlo Ruspi.

Aurei sermones seu Homiliae /

CCBE S. XVI

Apuntamientos de todos los sermones dominicales, y sanctorales : de primero de deziembre, y de aduie[n]to, hasta ultimo de febrero, y principio de Quaresma /

Mode of access: Internet.

Horario reflexivo /

RBC: Publisher's advertisements on endpapers and p. [4] of cover.

Memoir, historical and political, on the northwest coast of North America, and the adjacent territories : illustrated by a map and a geographical view of those countries.

References: Howes, U.S.IANA, no. G.389.

Granada rendida. Romance endecasílabo, premiado por la Real Academia Española en Junta que celebró el dia 22 de Junio de 1779.

Mode of access: Internet.

Benthic foraminiferal record of the Pleistocene uplift of the sedimentary deposits of the Burica Peninsula (Costa Rica-Panama) as a result of Cocos Ridge subduction beneath the Central American Arc

This study used paleobathymetric interpretations from benthic foraminiferal assemblages to determine the timing of the initial subduction of the Cocos Ridge beneath the Costa Rica-Panama Arc and the associated amount of uplift. Forty-seven samples from four stratigraphic sections of the Burica and the Armuelles formations yielded 217 identified species. Foraminiferal paleoecology and cluster analyses indicated paleobathymetric differences within and between the sections. Maximum and minimum uplift rates were calculated from the biochronology, elevation, paleobathymetry and estimated eustatic changes. Large decreases in paleobathymetry were mainly due to the initial middle Pleistocene subduction of the Cocos Ridge in less than 0.5 Ma. Uplift rates were uneven across the Burica Peninsula, as follows: La Vaca 4.5–0.8 m/ky, Rabo de Puerco 2.8–0.7 m/ky, San Bartolo–Chiquito 2.7–0.8 m/ky, and eastern coast 8.0–1.5 m/ky. These differences probably resulted from Cocos Ridge asymmetry and differential uplift of tectonic blocks.

Modelo animal da Doença de Parkinson baseado na expressão de alfa - sinucleína: caracterização comportamental, eletrofisiológica e avaliação dos efei tos da estimulação da medula espinhal

Parkinson disease (PD) is associated with motor symptoms and dopaminergic cell loss in the nigrostriatal pathway. Alpha-synuclein is the major component of the Lewy bodies, the biological hallmarks of disease, and has been associated with familial cases of PD. Recently, the spinal cord stimulation (SCS) showed to be effective to alleviate the Parkinson symptoms in animal models and human patients. In this project, we characterized the motor and electrophysiological effects of alpha-synuclein overexpression in the substantia nigra of rats. We further investigated the effects of spinal electrical stimulation, AMPT and L-dopa administration in this model. Method: Sprague-Dawley rats were injected with empty viral vector or the vector carrying the gene for alpha-synuclein in the substantia nigra, and were tested weekly for 10 weeks in the open field and cylinder tests. A separated group of animals implanted with bilateral electrode arrays in the motor cortex and the striatum were recorded in the open field, during the SCS sessions and the pharmacological experiments. Results: Alpha-synuclein expression resulted in motor asymmetry, observed as the reduction in use of contralateral forepaw in the cylinder test. Animals showed an increase of local field potential activity in beta band three and four weeks after the virus injection, that was not evident after the 5th week. AMPT resulted in a sever parkinsonian state, with reduction in the locomotor activity and significant peak of oscillatory activity in cortex and striatum. SCS was effective to alleviate the motor asymmetry at long term, but did not reduce the corticostriatal low frequency oscillations observed 24 hs after the AMPT administration. These oscillations were attenuated by L-dopa that, even as SCS, was not effective to restore the locomotor activity during the severe dopaminergic depletion period. Discussion: The alpha-synuclein model reproduces the motor impairment and the progressive neurodegenerative process of PD. We demonstrated, by the first time, that this model also presents the increase in low frequency oscillatory activity in the corticostriatal circuit, compatible with parkinsonian condition; and that SCS has a therapeutic effect on motor symptom of this model.

Determinação da composição química de quatro variedades de feijão caupi (Vigna unguiculata L. Walp) cultivadas em solo potiguar

The cowpea (Vigna unguiculata L. Walp) is a major food crops in northeastern Brazil. In Rio Grande do Norte, the cowpea, vigna beans or cowpea, as it is known, has great socioeconomic importance as a source of nutrients in food, with great emphasis among agricultural products. To improve productivity and resistance to pests, two cultivars were developed exclusively by EMPARN (Agricultural Research Corporation of Rio Grande do Norte), for breeding. The samples were provided by EMPARN, two improved (Potiguar and Laugh year) and two landraces (Rib of beef and Canapu). The seeds were ground and made into flour samples and the determination of moisture and ash by graviméticos methods, lipids by Soxhlet extraction, fibers with determiner fiber, carbohydrates by difference and minerals by ICP-OES were performed except the match analyzed by UVvis. The results showed a high fiber content (55.55% and 55.32% and 50.04% improved samples and 50.32% creole samples) and protein (25.52% and 25.27% improved and 27 samples, 23% and 24.99% creole samples). Comparing the results of the mineral content, the improved cultivars stood out in relation to Ca, Co, P, Mg, Mo and Na. Creole cultivars showed better results for Cu, Cr (low), Fe, Mn, Ni, K and Zn. The results will be important in future nutritional research and to build a table of Brazilian chemical composition of foods.