Morphological and biochemical alterations activated by antitumor clerodane diterpenes

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Fresamento de madeiras de média densidade: MDF

The technological expansion and market manufactured wood as wood paneling makes the research of processes involving this material are increasingly necessary . The present study examines the milling process MDF - fiberboard with average density endmill with helical teeth , with the analysis of the surface finish by evaluating the surface roughness ( Ra) and analysis of the power consumption . We analyzed three types of cuts in milling : concordant , discordant , and cut top . We used 5 rpm (6000 , 8000 , 10000 , 12000 and 14000 RPM) , establishing five-speed cutting, 301 , 402 ,502, 603 and 703 m / min respectively. Five forward speeds and 4, 6, 8, 10 and 12 m / min. Each condition was repeated six times , totaling 180 tests. The results of roughness were obtained from rugosimeter data and the power consumption were obtained by Hall-effect sensor . These results were statistically analyzed using analysis of variance and Tukey test . Finally it was concluded that there are few significant differences between the results themselves vary roughness when cutting speeds and feed and no major differences in power consumption . The best surface quality and lower power consumption were for cutting speed of 703 m / min . To varying forward speed , the speed of 4 m / min showed better surface quality and lower power consumption

Um estudo sintático-semântico das preposições em complementos verbais de webjornais paulistas

The main goal of this work is to evaluate the realization of the linguistic phenomenon of preposition and also to investigate how current normative pressures influence the production and the perception of processes of variation and change in Brazilian Portuguese. We analyze the use of prepositions a and para in verbal complementation contexts in contemporary journalistic texts from São Paulo’s press – the web newspapers. The contexts considered are constructions with complements of direction, movement with transference, material transference, and verbal/perceptual predicators (Berlinck, 1996; Corrêa, Cançado, 2006). Because written texts tend to be more conservative (i.e. more normative) this research provides an important linguistic investigation that contributes to the sociolinguistic knowledge of the language. However, the newspapers also tend to reflect the use, so they constitute a privileged place for us to understand the conflicting relationship between ‘norm’ and ‘use’. Besides this, the research is relevant for General Linguistics for considering linguistic and extralinguistic factors which determine the use and frequency of the prepositions, like syntactic-semantic relations between the preposition, the verb, the complement, and the text genre. We collected data from web newspapers from Araraquara, with small and medium circulation. Based on previous results, we have ascertained the predominance of the use of the preposition a in the newspapers from São Paulo in the 20th century. However, we have also ascertained representative records of variation... (Complete abstract click electronic access below)

Avaliação dos gases de efeito estufa a partir do carvão

This paper addresses the context of emissions of Greenhouse Gases (GHG) from activities related to Coal, called fugitive emissions. The survey of factors, development, analysis, and suggestions for controlling emissions are conducted in order to reduce risks to the environment and people around it. The greenhouse gases absorb radiation, emitted by the Earth’s surface, and hinder their escape into space. This process is essential to terrestrial life. Increasing the concentration of those gases in the atmosphere has led to an increase in the terrestrial temperature. A selection of processes that emit gases and the study and development of calculations for measuring fugitive emissions applied in different sources from coal are performed. The greenhouse gases can be released from the extraction, processing, storage, and transportation of fossil fuels to the end consumer. Coal has 4 main fugitive factors: mining, post-mining, oxidation at low temperature, and uncontrolled combustion. The coal formation process produces methane (CH4) and carbon dioxide (CO2), being the methane, the main greenhouse gas from the coal mining and handling. The types of activities and the weight of each in the issuing process are observed. It is also made comparisons between the countries with the highest emissions rates. Are evaluated what has been done and what is needed to decrease emissions, for example the use of gas as an alternative fuel for energy generation

Impacto da ABNT NBR 15575 na qualidade da construção civil

The quality in construction is increasingly a concern in this sector, in view of the occurrence of problems in civil works, even when a contractor is certified by ISO 9001. The ISO 9001 certification does not ensure the maintenance of quality because it only establishes the requirements for a quality management system (QMS) to ensure standardization of processes and products. With the development of ISO 15575, standard performance, the builders took on a quality parameter with the requirements established by this Standard, which must be met. Thus, the implementation of a quality management system (QMS) becomes essential, showing users the concern for quality. This study aimed to verify, through a case study, the impact of NBR 15575 quality construction and how that standard of performance may be the key element of ISO 9001 to ensure quality maintenance of civil works

Exposição ambiental ao chumbo: um problema de áreas contaminadas próximas a fábricas de baterias

The concentration of metal pollutants such as lead (Pb), has grown and developed in populated areas due to pollution and other human activities. Consequently, the potential for achieve this element food chain has also increased. Lead is very toxic to humans, especially to children, and exposure to lead can cause adverse health effects mainly on human nervous system, bone marrow and kidneys, interfering with chromosomal or genetic processes. This paper presents an overview of the main aspects related to environmental contamination by lead from battery plants. The assessment of an area contaminated by lead in Bauru-SP next a battery factory was reported in this work as well as the entire history of monitoring, classification and application of processes applied by CETESB since 2002. Analyzing the issue in its economic aspects, we found that the degradation of the environment is directly related to the development model adopted by the capitalist system, which is based on the law of supply and demand for products and services. The data presented indicate that Brazil still needs a broader policy where government agencies, industries and population through awareness can be united for the same purpose: to preserve life

Analise do sistema de medição em peças aeronaúticas através do estudo de R&R (repetibilidade e reprodutibilidade)

The Measurement System Analysis (MSA - Measurement System Analysis) is a statistical methodology developed to study and analyze the behavior of the measurement systems, and, therefore, allow the increased of the confidence readings performed by measuring instruments. It’s widely used in the automotive industry since the 90’s and is a mandatory requirement for the approval of the parts according to ISO Standard of the automotive sector. However, the aerospace industry doesn’t require this type of Study, once which the vast majority of aeronautics parts have characteristics (dimensions) with very tight tolerances, closed, ie, at the home of microns. This work aims to create lists of recommendations for definitions of measuring instruments in developing of control plans, which correlates tolerances fields of characteristics for different settings and acceptance of the instrument, classified as optimum, recommended and not recommended, through of the study of R&R (Repeatability and Reproducibility) in aeronautics parts. Every methodology of the experimental part was based on modern strategy of continuous improvement, the DMAIC (Define Measure Analyze Implant Control), in order to achieve better measurement method used in the control of milling aeronautics parts, identifying and reducing the variations of the measurement process. The results of the R&R Study in large part of measuring instrument manuals were considered acceptable and/or recommended, ie with values of %P/T and %RR lower than 30%, providing statistical data which have enabled the elaboration of tables of recommendations, which, from this work, have turned into very important documents and aid for Process Engineering, having in their hands a technical study able to identify which is the most appropriate instrument to get a more robust dimensional... (Complete abstract click electronic access below)

Planejamento e organização das atividades de manutenção em instalações elétricas prediais e seus componentes

Are presented on this paper, concepts of corrective, preventive and predictive maintenances, following the prerequisites for planning and implementation of a maintenance plan. You also find the theoretical introduction of some measurement instruments accompanied by the necessary and recommended activities during routine maintenances of the electrical equipments in a building installation. Using case study, it is possible to assess a real maintenance plan applied to two occupied floors in a financial institution. The developing of a case study consolidates the effectiveness of the present concepts on this theoretical introduction and shows that the current maintenance plan can be improved in order to obtain better results on company productivity and reliability of equipments. As a conclusion, we can notice the importance of a solid maintenance plan and the need of including this theme on the graduation in Electrical Engineering

Relações públicas e educação corporativa: um estudo multicasos

In scenery where the information and the knowledge are acquiring more and more importance, the corporations are looking for alternatives to remain themselves competitive in the market, once the competition happens globally. The current work presents, through bibliographic research and multicases studies, one possibility for the organizations that wishes to increase their competitiveness and look into the participation of the Public Relations professional in the development of Corporative Education programs aiming (at) the continuing education of a very important audience for the organizations, the intern one Through courses and trainings that can happen by presence or remote way, the Corporative Educational programs have as target developing of the critical competence to the organizations, aiming to solve internal problems and reach the best position against competitors. This work is aimed to present how the Public Relation professional can act like a facilitator agent for the education of the intern public of the companies through the Corporative Education. The courses offered through these programs aim to keep the professional always updated, besides to disseminate the values, culture and company’s legacy. At this point, the participation of the Public Relations is appointed to a possibility to strengthen the organization’s internal communication and promote a larger engagement and participation of the employees

Avaliação de sistemas de pultrudados com diferentes tipos de matrizes para aplicação em cabos condutores

In the last decades it has been observed a substantial developing of the electrical energy demand in the societies all over the World. In consequence the electrical energy distribution companies are increasing the quantity of electrical energy through the electrical energy conductor cables, which had grown the sag in the towers of energy transmission. Furthermore, the construction of more transmission towers brings a lot of troubles due environmental protection laws. In this way, looking forward to increase the quantity of electrical energy transmitted through electrical cables conductors, reduce the need of constructing new transmission towers and the sag in them, we suggest in this work the replace of the traditional core of the conductors cables commonly used, made of steel, by a core made by a composite material, which one is made by carbon fibers pultruded with polymeric resins as matrix. In a order to evaluate if the resins more commonly used in structural composites can be applied as matrix to make possible to use the composite material as a core, we made carbon fibers systems pultruded with epoxy, phenolic and polyester resins as matrix and a mechanic and physic-chemistry characterization was done on the systems by Tensile and Poisson tests, differential sprobe calorimetry (DSC), thermogravimetric analysis (TGA) and Fourier transformed infrared spectroscopy (FTIR), following their correspondents standards

Estudo de casos de seleção dos materiais e processos para a fabricação de fuselagens

This work proposes a study on the materials selections and processes for the manufacture of aircraft and showing a methodology to reduce the manufacturing cost. The DFMA can be understood as a methodology that aims at reducing manufacturing and assembly costs and coupled with the increase of product quality through design simplifications. The most commonly material used in the manufacture of aircraft is aluminum alloys due to these possess great structural strength, good elasticity, and being stainless having a low specific weight (about 1/3 that of steel), reducing the weight of the aircraft. A case study in which an operation in the process of verifying the quality was generating unnecessary costs time / man for the company was also developed. The problem solution was simple, just removing the attachment process. It was found that the DFMA methodology is extremely important for the simplification of processes and projects, contributing to the reduction of manufacturing costs of aircraft

MiLoc-Sys Mobile: gestão em locação

Companies that invest in current technologies maintain themselves updated, improve their business rules and anticipate themselves against rivals providing a better service to their customers. This project aims to develop an ERP - Enterprise Resource Planning module for Android which complements an existing manager system and, that attends the needs of a rental equipment business for civil building, i.e., it improves the communication channel company-client and betters the identification and control of products. During the developing of this project, it was necessary to study the company business rules, analyze the requirements and the appropriate technologies. This project was organized in two parts, contemplating e ach of these needs. It were implemented specific modules for generate budgets and pre-orders in the first part and, the use of radiofrequency tags in the second one. Thus, it was possible to assign mobility to company business rules so that a better rental service can be provided and the equipments can be better managed

Utilização de técnicas de planejamento de experimentos na análise de viabilidade de alterações no processo de pintura de grades Antracite em uma indústria automotiva

The search for better performance and competitive advantage in the current market scenario has made organizations keep their focus on quality planning and the use of effective techniques aimed at continuous improvement and optimization of processes and resources. The situation is not different for the painting process in the automotive industry, which has a significant amount of variables and influential external factors. This work, developed at General Motors in São José dos Campos, aims to analyze the feasibility of changing the painting process of the pickup S10 railings in the Antracite color located in the main line to the another line located in a Painting Repair Booth at the plant and, therefore, to study the possibility about reducing the window of cure for Antracite’s enamel by using Design of Experiments’ techniques. Applying this method is possible to find the best arrangement among studied factors of Painting Repair Booth that are, in this case, the Temperature, in Celsius degrees, and Skid’s Steps, in seconds, and it’s also possible to get their behavior according to quality requirements specified by GM rules for the Brightness and Paint Adhesion on the part. As a result, it can conclude that is possible to paint the S10 Antracite railings in the painting process’ line of Painting Repair Booth, and with the new configuration obtained by the Design of Experiments for the process variables, there are significant gains related to the parts’ quality, costs reduction and the optimization of production capacity, much in the main line as in the line of the Painting Repair Booth

Ciclo PDCA e ferramentas da qualidade em operações e serviços de e-commerce

The market has forced companies to maintain high levels of control over their processes , ensuring a product or service quality to its customers . This study comes in the issuance and registration carried out in a company of e-commerce , which is showing problems with the values of weights and dimensions used in the cases cited . The need to eliminate wasteful spending freight caused by shipment of products weighing more than the reality, and to increase the reliability of the information used in the management of processes led to the planning of this project . This work focuses on the development of a PDCA cycle to work in the identification and correction of the causes of the problem , in order to neutralize the current complications and ensure that the problem does not appear again. To aid the mapping of the processes involved , identifying the causes of the problem and implementation of the proposed improvements were used quality tools such as flowcharts , Ishikawa diagrams , Pareto diagrams , and applied statistics

Releitura eliasiana de Sérgio Buarque de Holanda: democracia e personalismo no Brasil contemporâneo

Pós-graduação em Ciências Sociais - FFC