Identificação de regiões com variação no número de cópias de segmentos de DNA em bovinos de raças autóctones espanholas

Pós-graduação em Genética e Melhoramento Animal - FCAV

Análise da diversidade genética em Curimbatá (Prochilodus) da Bacia do Prata e Amazônia

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Anatomia floral de espécies de Cyperaceae (Poales)

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Busca de novos alvos terapêuticos no tratamento de câncer de pulmão utilizando ferramentas de biologia de sistemas

A quimioterapia e uma das formas de tratamentos para o câncer, cujo processo e pela aplicação de medicamentos que alteram a síntese de DNA, interrompendo a divisão celular. No caso do câncer de pulmão, a difículdade está no fato de que as células cancerígenas criam quimiorresistência após um determinado período de tempo. Se o indivíduo desenvolver o câncer de pulmão novamente, deverá ser aplicado outro quimioterápico no paciente, e assim por diante. Nos tratamentos atuais são utilizados combinações de drogas para contornar o problema da quimiorresistência. Este trabalho utilizou a biologia de sistemas para encontrar novos alvos protéicos para auxiliar no desenvolvimento de novos quimioterápicos para o tratamento do câncer de pulmão. Foi construída uma rede baseada nos alvos protéicos já conhecidos. A rede foi expandida com o intuito de buscar quais são as proteínas que interagem com os alvos protéicos á conhecidos. Após a expansão, foram utilizadas análises de centralidades para evidenciar as proteínas mais importantes na rede, e correlacionamos com informação de expressão gênica para verificar se as proteínas mais importantes do ponto de vista topológico estão diferencialmente sub ou super expressas. A análise de centralidade junto a mostra dos dados de expressão gênica convergiu para um bom resultado, foi possível evidenciar algumas proteínas que podem ser utilizadas como novos alvos quimioterápicos

Dinâmica de metabólitos secundários em variedades de Casearia sylvestris e estudos iniciais de biologia molecular relacionados aos genes das enzimas GGPP sintase e Chiquimato desidrogenase (DHS)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Produção otimizada de biocelulose utilização de biologia molecular de micro-organismos

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Análise citogenética clássica, molecular e ultraestrutural em escorpiões da família Buthidae: um enfoque evolutivo

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Educação ambiental e formação de professores de biologia no município de piracicaba/speducação ambiental e formação de professores de biologia no município de Piracicaba/SP

Early this century, several crises are intertwined and the environmental crisis is the most global of them all. In this context, emerged as an environmental education learn to overcome the crisis. This article aims to discuss the ideas of biology teachers in the city of Piracicaba-SP on Environmental Education and from there to reflect on the theme of inclusion in the initial training of teachers. The methodology used a structured questionnaire-based instrument VOSTS (Views on Science-Technology-Society), produced by Aikenhead and Ryan (1992) and the data were analyzed qualitatively. The results indicate that the biology teachers surveyed still have a naive conception of environmental education and training courses need to commit to structural and curricular changes that make the effective insertion of the subject in teacher training in the region studied.

Variação nômade: Henry Miller, filosofia e o combate contra o juízo

We discuss Henry Miller's novel Tropic of Cancer based on the concept of nomadism, as coined by Deleuze and Guattari. The relation between philosophy and literature is very productive for both. A phenomenon of dual capture between these two areas that is characteristic of a nomadic thinking: literature that engenders philosophy which, in turn, engenders literature, establishing connections, new relations between terms in a distinct nomad variation that dismisses the classical image of thought of its eminence: a perspective between philosophy and literature as form of discussing the nomadism in Miller's novel. Thus, the linkage between philosophy and literature aims to capture the Millerian paths on this new space of thought, which is achieved by giving up any origin, human or divine, and stands as productive thought that affirms the real in a combat waged against the faculty of judgment, or simply of Judgment, in all its forms.

Dirigiu-se para a sede social da Elite Flor da Liberdade e ofereceu um banquete aos visitantes: sobre a variação de proposições em complementos verbais

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Como o ensino vê a variação?

Thinking about the correlations between linguistic variation and education is both necessary and urgent if we wish to make language teaching more appropriate, fairer and more meaningful. I take, on one hand, already well-established concepts derived from research on language: the variable nature of language (in space, time, situations) and the intrinsic relationship between this variation and social structure, the communicative needs of speakers, the needs and desires that speakers have to build their social identity. On the other hand, we found out that the teaching of Portuguese language has usually been based on a vision that assumes the language as a static reality. I propose to contrast the two components of this issue, to reveal where, and if, any relationship has been established, and where it is to be built. In the first instance, I seek to evaluate the bond – how one speaks about change when this issue comes to be focused; in the second, I seek the reasons for absence - ignorance or indifference?

Variação e mudança linguística: panorama e perspectivas da sociolinguística variacionista no Brasil

Since the 1970s many research groups have emerged in Brazil in the area of Sociolinguistics, seeking to investigate language in relation to social factors that distinguish different speech communities to deconstruct the idea of linguistic homogeneity. Many of the works have been based on variationist sociolinguistics (LABOV, 2008 [1972]), for which variation and change are inherent to languages, i.e., heterogeneous structures are part of the speakers’ linguistic competence, as a cultural phenomenon motivated by linguistic and extralinguistic factors. Our aim, in this article, is to address the paths of Sociolinguistics since its beginning as a science, focusing mainly on the variationist strand, by recalling its key-concepts and methodology, and to present an overview of the research works conducted in Brazil in this field nowadays.

Contribuições teóricas e metodológicas para a constituição de corpora em pesquisa de variação/mudança linguística

This papers deals with theoretical and methodological problems concerning the definition of criteria for the selection of sources for the study of language. Our work discussed the use and the importance of genre in the process of corpora construction as variation search – synchronic and diachronic.

Variação e mudança lexical no português brasileiro do século XX: um estudo descritivo-comparativo

In this article, we analyze only the processes of lexical expansion related to the reuse and recontextualization of words. We selected 50 names of animals in Brazilian Portuguese (PB). These words were found in two dictionaries and only the definitions connoting human actions and attributes were used. Through this study linguistic principles that are practically consensual were confirmed. We highlight the polissemic phenomenon as one of the factors that most contribute to the economy of the linguistic system.