Análise químico-farmacêutica do ácido fusídico em formulações de creme

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Validation of high-performance liquid chromatographic method for analysis of fluconazole in microemulsions and liquid crystals

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Efeito de tarefa dupla no controle postural de adultos idosos: acoplamento sensório-motor

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Efeitos de uma tarefa dupla e demandas da tarefa no controle postural de adultos jovens

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Dinâmica secular rotacional de corpos tri-axiais: expansão de V em ressonâncias de primeira ordem

Consider a finite body of mass m (C1) with moments of inertia A, B and C. This body orbits another one of mass much larger M (C2), which at first will be taken as a point, even if it is not completely spherical. The body C1, when orbit C2, performs a translational motion near a Keplerian. It will not be a Keplerian due to external disturbances. We will use two axes systems: fixed in the center of mass of C1 and other inertial. The C1 attitude, that is, the dynamic rotation of this body is know if we know how to situate mobile system according to inertial axes system. The strong influence exerted by C2 on C1, which is a flattened body, generates torques on C1, what affects its dynamics of rotation. We will obtain the mathematical formulation of this problem assuming C1 as a planet and C2 as the sun. Also applies to case of satellite and planet. In the case of Mercury-Sun system, the disturbing potential that governs rotation dynamics, for theoretical studies, necessarily have to be developed by powers of the eccentricity. As is known, such expansions are delicate because of the convergence issue. Thus, we intend to make a development until the third order (superior orders are not always achievable because of the volume of terms generated in cases of first-order resonances). By defining a modern set of canonical variables (Andoyer), we will assemble a disturbed Hamiltonian problem. The Andoyer's Variables allow to define averages, which enable us to discard short-term effects. Our results for the resonant angle variation of Mercury are in full agreement with those obtained by D'Hoedt & Lemaître (2004) and Rambaux & Bois (2004)

O clima urbano de Rancharia (SP)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Estudo da assimetria da fossa mandibular, em crânios secos de crianças pelo método radiográfico

The Temporomandibular Joint is a noble structure of the complex mandibular, a lot of research was conducted on the to signs and symptoms of the alterations that attack those structures. ln spite of the high incidence of the DTM in children, there's little knowledge about it, wich makes difficult the treatment Desorders Craniomandibulares (DCM) or Desorders Temporomandibulars (DTM). The Temporomandibular Joint is composed basically by three elements: bones, muscles and disk, in relation to bony part, we have the fossae mandibular that is part of the temporary bone and wich houses the condyle mandibular, accomplishing the articulation among the cranium and the jaw (it leaves piece of furniture of the articulation). Our intention in that work was of verifying a possible asymmetry of the fossae mandibular on the left side and of the right side in relation to two straight line: a straight line that coincided with the plane medium sagittal and another perpendicular straight line to the plan medium sagittal. Analyzing, the fossae mandibular in 91 dry craniums of children, with age varying between four months of life intrauterina and five years, in x-rays in that the incidence was cranium-flow, we could end that: in spite of we find statistical significance in relation to that asymmetry, clinic cannot affirm that interferences on occlusion exists for that asymmetry

Um modelo cognitivo baseado na atenção para consciência em robôs inteligentes

Understanding consciousness is one of the most fascinating challenges of our time. From ancient civilizations to modern philosophers, questions have been asked on how one is conscious of his/her own existence and about the world that surrounds him/her. Although there is no precise definition for consciousness, there is an agreement that it is strongly related to human cognitive processes such as: thinking, reasoning, emotions, wishes. One of the key processes to the arising of the consciousness is the attention, a process capable of promoting a selection of a few stimuli from a huge amount of information that reaches us constantly. Machine consciousness is the field of the artificial intelligence that investigate the possibility of the production of conscious processes in artificial devices. This work presents a review about the theme of consciousness - in both natural and artificial aspects -, discussing this theme from the philosophical and computational perspectives, and investigates the feasibility of the adoption of an attentional schema as the base to the cognitive processing. A formal computational model is proposed for conscious agents that integrates: short and long term memories, reasoning, planning, emotion, decision making, learning, motivation and volition. Computer experiments in a mobile robotics domain under USARSim simulation environment, proposed by RoboCup, suggest that the agent can be able to use these elements to acquire experiences based on environment stimuli. The adoption of the cognitive architecture over the attentional model has potential to allow the emergence of behaviours usually associated to the consciousness in the simulated mobile robots. Further implementation under this model could potentially allow the agent to express sentience, selfawareness, self-consciousness, autonoetic consciousness, mineness and perspectivalness. By performing computation over an attentional space, the model also allows the ...

Otimização de método para determinação de antimicrobianos em cama de frango por clae-flu

O extraordinário desenvolvimento da produção avícola, particularmente no setor de frango de corte, tornou o Brasil um importante produtor e exportador de carne de frango. Esse fato aliado a proibição da utilização de cama de frango como ração para ruminantes pela Instrução Normativa nº15 de 17 de julho de 2001, fez com que este resíduo se tornasse um problema ecológico e de saúde pública de alta relevância, tanto pelo volume de resíduos gerado, quanto pela composição do mesmo, que pode conter diversos fármacos utilizados neste tipo de manejo, além de uréia, que após a oxidação natural no ambiente, resulta em nitrato que tem alto poder de contaminação de mananciais hídricos, principalmente subterrâneos. Dentre as substâncias que podem estar presentes na cama de frango, estão os antimicrobianos, utilizados como promotores de crescimento das aves. No Brasil, são pouquíssimos os trabalhos dedicados a investigar a ocorrência e o impacto ambiental de antimicrobianos. Desta maneira, este trabalho teve como objetivo otimizar e validar método para análise de três fluoroquinolonas (ciprofloxacina, norfloxacina e enrofloxacina) em cama de frango. O método estudado baseou-se em trabalhos da literatura em que moléculas similares foram analisadas em diversas matrizes, compreendendo a extração em ultrassom com acetonitrila acidificada com ácido acético (3% v/v) e análise por CLAE-FLU, modo isocrático com a fase móvel composta por 0,02 M H3PO4:ACN (83:17, v/v). Foram avaliados os parâmetros cromatográficos quanto à resolução, eficiência, linearidade e limites de detecção e quantif-1 para os três analitos. O tempo de análise do método cromatográfico otimizado é de 7,5 minutos. Avaliou-se também o efeito de matriz que foi significativo para norfloxacina e ciprofloxacina, correspondendo a 16 e 20%, respectivamente. Para a enrofloxacina a amostra...

Trauma traqueal associado à fratura mandibular: relato de caso

Introduction: The mandibular injuries account for about 20% to 50% of cases of facial fractures. Some consider the jaw the second most commonly fractured bone of the skull, and is the only mobile bone of the facial framework, which results in decreased stability compared to the trauma. When one takes into account the degree of airway obstruction in patients with facial fractures, the problem becomes much more serious since it is one of the most troubling complications of trauma. Objective: the relevance of the topic is aimed to report a case of a patient victim of mandibular fracture associated with trauma to the trachea. Case report: Case report: Patient 24 years old patient with tracheal trauma concomitant mandibular fracture surgically treated in conjunction with the thoracic surgeon. After 5 months postoperatively, the patient is in good condition general, no complaints. Final comments: This form is observed that the key to proper treatment of tracheal trauma associated with facial fractures is the knowledge of the type of injury, and an accurate diagnosis multidisciplinary.

Determinação de fumosina B1, por CLAE: estudo da estabilidade do derivado fumonisina B1-orto-ftaldialdeído

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Determinação de fumonisina B1 por CLAE: estudo da estabilidade do derivado fumonisina B1-orto-ftaldialdeído

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Validation of analytical methodology for quantification of cefazolin sodium by liquid chromatography

A reversed-phase high performance liquid chromatography method was validated for the determination of cefazolin sodium in lyophilized powder for solution for injection to be applied for quality control in pharmaceutical industry. The liquid chromatography method was conducted on a Zorbax Eclipse Plus C18 column (250 x 4.6 mm, 5 μm), maintained at room temperature. The mobile phase consisted of purified water: acetonitrile (60: 40 v/v), adjusted to pH 8 with triethylamine. The flow rate was of 0.5 mL min-1 and effluents were monitored at 270 nm. The retention time for cefazolin sodium was 3.6 min. The method proved to be linear (r2 =0.9999) over the concentration range of 30-80 µg mL-1. The selectivity of the method was proven through degradation studies. The method demonstrated satisfactory results for precision, accuracy, limits of detection and quantitation. The robustness of this method was evaluated using the Plackett–Burman fractional factorial experimental design with a matrix of 15 experiments and the statistical treatment proposed by Youden and Steiner. Finally, the proposed method could be also an advantageous option for the analysis of cefazolin sodium, contributing to improve the quality control and to assure the therapeutic efficacy

Simulação numérica do escoamento em difusores radiais com discos frontais fixos e móveis

Pós-graduação em Engenharia Mecânica - FEIS

Desenvolvimento de detector eletroquímico para cromatografia líquida de alta eficiência baseado em um eletrodo modificado com nanopartículas metálicas para determinação de ácidos carboxílicos em vinhaça de cana-de-açúcar

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)