Impacto social do transplante cardíaco

Pós-graduação em Serviço Social - FCHS

Um dos desafios da questão social: adolescentes em cumprimento de medida sócioeducativa em Araraquara-SP

Pós-graduação em Serviço Social - FCHS

Os caminhos da participação e do controle social na saúde: estudo das realidades do Brasil e Espanha

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Análise organizacional do partido da social democracia brasileira no estado de São Paulo (1988-2006): a estrutura relacional e o capital político

Pós-graduação em Ciências Sociais - FCLAR

Influence of the dopaminergic system, CREB, and transcription factor-B on cocaine neurotoxicity

Cocaine is a widely used drug and its abuse is associated with physical, psychiatric and social problems. Abnormalities in newborns have been demonstrated to be due to the toxic effects of cocaine during fetal development. The mechanism by which cocaine causes neurological damage is complex and involves interactions of the drug with several neurotransmitter systems, such as the increase of extracellular levels of dopamine and free radicals, and modulation of transcription factors. The aim of this review was to evaluate the importance of the dopaminergic system and the participation of inflammatory signaling in cocaine neurotoxicity. Our study showed that cocaine activates the transcription factors NF-κB and CREB, which regulate genes involved in cellular death. GBR 12909 (an inhibitor of dopamine reuptake), lidocaine (a local anesthetic), and dopamine did not activate NF-κB in the same way as cocaine. However, the attenuation of NF-κB activity after the pretreatment of the cells with SCH 23390, a D1 receptor antagonist, suggests that the activation of NF-κB by cocaine is, at least partially, due to activation of D1 receptors. NF-κB seems to have a protective role in these cells because its inhibition increased cellular death caused by cocaine. The increase in BDNF (brain-derived neurotrophic factor) mRNA can also be related to the protective role of both CREB and NF-κB transcription factors. An understanding of the mechanisms by which cocaine induces cell death in the brain will contribute to the development of new therapies for drug abusers, which can help to slow down the progress of degenerative processes.

Aplicação de análise de sobrevivência no estudo da imobilidade tônica e do comportamento de reintegração social de perdizes (Rhynchotus rufescens)

Pós-graduação em Genética e Melhoramento Animal - FCAV

Perinatal Periodontal Disease Reduces Social Behavior in Male Offspring

Objective: Our objective was to verify whether prenatal maternal periodontitis is a risk factor for the development of central nervous system disorders in rats. Methods: Periodontitis was induced by placing a ligature around the upper and lower first molars in 9 female Wistar rats (experimental group); 9 rats were left unligated (control group). The maternal general activity in an open field was observed on gestational day (GD) 0, GD 4, and GD 14, and the maternal performance was assessed on the second day after birth. The pups' play behavior was assessed on postnatal day 30. The relative level of reelin was measured in the frontal cortex by real-time PCR analysis. Results: The results showed that, compared with the control group, (1) the general activity in female rats with periodontitis was decreased, (2) the maternal performance of these rats was not modified by periodontitis, (3) the play behavior of pups from dams with periodontitis was decreased, and (4) there were no differences in the frontal cortex reelin levels of pups from dams with periodontitis. Conclusions: We conclude that pre- and postnatal periodontitis induces maternal sickness behavior and reduces the pups' play behavior without interference with frontal cortex reelin expression. Copyright (C) 2012 S. Karger AG, Basel

Implant-retained finger prosthesis with modified retention system

Background: Amputations affect both the physical and the psychological aspects of an individual, causing significant impact on self-esteem. The main causes of finger amputations are work-related accidents with dangerous machinery, road traffic accidents, and animal bites, as well as systemic diseases such as diabetes. This report aims to describe a simple technique for fabrication of implant-retained finger prosthesis with a modified base of the retention system.Case Description and Methods: The O-Ring retention system was used with a modified hexagon-shaped base and a metallic capsule adapted to the acrylic resin to attach the prosthesis to the implant.Findings and Outcomes: The prosthesis was made with silicone, and after osseointegration, it was installed without complications, leading to a patient satisfied with the end result and encouraged to return to social life.

La política de salud en Cuba en el nuevo milenio: la contribución del Trabajo Social

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Ordem social, Polícia Civil e justiça criminal na cidade de São Paulo (1889-1930)

The article aims to review the discussion on police role within institutional reform in São Paulo First Republic implementation. The main argument refers to the formation of brazilian judicial system and to the continuity of the debate on public policies reforms, administration of justice and police control over lower social classes, by means of a criminalization of the poverty. The judicial administration was reformed, but that opened space for police institutions to act without constraints. Despite theses changes, state institutions were also used by tradicional social elites in neo-patrimonial ways, allowing the maintenance of unlawful practices within the system.

Economic growth, urbanization and social inequality: Reflections on the conservative Modernization

China is now facing a sudden change of redistribution of population in space as her urban population exceeds rural population. It seems necessary to learn others’ lessons by analyzing the urbanization of other developing countries, especially Brazil’s. To an extent, Brazil and some other developing countries have been unsuccessful in coordination for urbanization and improving living quality. The megacities in Latin America are the examples of swollen cities, and large groups excluded from the system of public services. It reflects in both short of infrastructures in many areas and high-levels of violence unique in the big cities in Latin America. Then the author summarizes Brazil’s lessons. Firstly, he describes the determinants in Brazil’s urbanization, especially the industrialization between 1930 and 1980. Secondly, the incentives for internal migration are analyzed, especially the industrial centralization in the southeast and the recessions in other areas. Finally, the characteristics of the present round of absorption of labor and the roots for the severe social inequality are discussed.

Abordagem técnica sobre os aspectos de uma rede social colaborativa

With the advancement of the gaming industry in the market, became evident the need for professionals working in this area. With this in mind, this paper attempts to create an environment where aspirants and professionals in creating games can interact. To get to this point, was built one system based on current technologies, and parad igms of software engineering system. So throughout this monograph the process of the system development is studied, using different technologies, and showing how it can work, the exchange of information and knowledge among the games creation lovers

Qualidade de vida e vulnerabilidade social na percepção do idoso

According to data from the World Health Organization, the older population will grow sixteenfold from 1950 to 2025 in comparison to a fivefold population growth in the same period, which is referred to by UNO as the “Ageing Era”. This places Brazil in the sixth position in the contingent of older individuals worldwide, with a number that is higher than 32 million. Considering how topics such as quality of life and social vulnerability are important in face of the growing older population, these topics must be furthered studied so that they can be understood as important variables for both better clinical practice and scientific research. To describe the social vulnerability and evaluate the quality of life of older individuals in a population hospitalized in the internal medicine ward of Bauru State Hospital. This is a descriptive qualitative study that was conducted by means of interviews and using Bardin’s discourse analysis. The inclusion criteria used in this study were: individuals at 60 years of age who were mentally capable of answering the proposed questions. Two categories concerning Quality of Life and Social Vulnerability emerged from the interviews. The following emerged from the theme Quality of Life: “Life as something important” and subcategories that involved feeling useful in society, having a supportive family, independence, optimism and joy and survival. Also, the following emerged from the theme Social Vulnerability: “Negative recognition of older individuals in society” and subcategories that involved lack of respect, functional disability, family indifference, housing-related insecurity, an inefficient health care system and loneliness. Quality of Life and Social Vulnerability are largely discussed themes in the present scenario. In this study, it was possible to perceive that the older population needs social support, effective public... (Complete abstract click electronic access below)

A relação educação e trabalho na legislação educacional brasileira: política pública, contexto econômico e social

Pós-graduação em Educação - IBRC

Entre ditos e não ditos: a marcação social de diferenças de gênero e sexualidade por intermédio das práticas escolares da Educação Física

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)