Associations of leisure-time physical activity with quality of life in a large, population-based sample of colorectal cancer survivors

Objective : To examine the associations between physical activity and quality of life for colorectal cancer survivors; and to describe the associations of medical and sociodemographic attributes with overall quality of life, and their moderating effects on the relationships between physical activity and quality of life.

Methods : Telephone interviews were conducted with 1,996 colorectal cancer survivors recruited through the Queensland Cancer Registry. Data were collected on current quality of life; leisure-time physical activity pre- and post-diagnosis; cancer treatment and side-effects; and general sociodemographic attributes. Hierarchical generalized linear models identified variables significantly associated with quality of life.

Results : After controlling for sociodemographic variables, disease-specific variables, treatment side-effects, and pre-diagnosis leisure-time physical activity, there were significant differences in quality of life scores by post-diagnosis physical activity category. Compared to participants who were inactive after their diagnosis, those who were sufficiently active had a 17.0% higher total quality of life score. Physical activity also had a significant independent positive association with the physical well-being, functional well-being, and additional concerns subscales of the FACT-C.

Conclusions : Our findings demonstrate that quite modest changes in leisure-time physical activity are associated with quality of life. Colorectal cancer survivors may benefit from a more active lifestyle.

The ocean sunfish Mola mola : insights into distribution, abundance and behaviour in the Irish and Celtic Seas

Here we provide baseline data on the distribution and abundance of Mola mola within the Irish and Celtic Seas, made during aerial surveys from June to October during 2003–2005. These data were considered in conjunction with concurrent observations of three potential jellyfish prey species found throughout the region: Rhizostoma octopus, Chrysaora hysoscella and Cyanea capillata. A total area of 7850 km2 was surveyed over the three years with an observed abundance of 68 sunfish giving a density of 0.98 ind/100 km2. Although modest, these findings highlight that the species is more common than once thought around Britain and Ireland and an order of magnitude greater than the other apex jellyfish predator found in the region, the leatherback turtle (Dermochelys coriacea). Furthermore, the distribution of sunfish sightings was inconsistent with the extensive aggregations of Rhizostoma octopus found throughout the study area. The modelled distributions of predator–prey co-occurrence (using data for all three jellyfish species) was less than the observed co-occurrence with the implication that neither jellyfish nor sunfish were randomly distributed but co-occurred more in the same areas than expected by chance. Finally, observed sunfish were typically small ([similar]1 m or less) and seen to either bask or actively swim at the surface.

Impacts of DG penetration in the Bamaga and Gununa isolated distribution networks

Isolated distribution systems are dispersed throughout regional Queensland to supply small isolated communities that are distant from the main supply grid. The costs of maintaining the electricity supply to these areas is costly; mainly due to the cost of diesel fuel. Furthermore, there is a community focus on climate change, and Ergon Energy aims to reduce the reliance on fossil fuels whilst optimising cost efficiencies and greenhouse gas emissions. The objective of this study is to examine the impacts of renewable energy sources in isolated power systems. For the locations studied, viable renewable energy sources have been integrated into these networks. Anticipated challenges and issues with the integration of the intermittent renewable energy sources were addressed, using mitigation techniques, including energy storage solutions. The investigation and findings demonstrated that network improvements can be achieved by an ideal level of renewable penetration, which has been the main focus of the project. The project involved the development and simulation of MATLAB Simulink and SINCAL models of the two isolated networks at Gununa and Bamaga. The subsequent analysis of these systems has shown a modest penetration level of renewables can be combined with energy storage solutions, which reduces fuel consumption and greenhouse gas emissions at these locations.

The association of cycling with all-cause, cardiovascular and cancer mortality: findings from the population-based EPIC-Norfolk cohort

Objectives
To investigate associations between modest levels of total and domain-specific (commuting, other utility, recreational) cycling and mortality from all causes, cardiovascular disease and cancer.

Design
Population-based cohort study (European Prospective Investigation into Cancer and Nutrition study-Norfolk).

Setting
Participants were recruited from general practices in the east of England and attended health examinations between 1993 and 1997 and again between 1998 and 2000. At the first health assessment, participants reported their average weekly duration of cycling for all purposes using a simple measure of physical activity. At the second health assessment, participants reported a more detailed breakdown of their weekly cycling behaviour using the EPAQ2 physical activity questionnaire.

Participants
Adults aged 40–79 years at the first health assessment.

Primary outcome measure
All participants were followed for mortality (all-cause, cardiovascular and cancer) until March 2011.

Results
There were 22 450 participants with complete data at the first health assessment, of whom 4398 died during follow-up; and 13 346 participants with complete data at the second health assessment, of whom 1670 died during follow-up. Preliminary analyses using exposure data from the first health assessment showed that cycling for at least 60 min/week in total was associated with a 9% reduced risk of all-cause mortality (adjusted HR 0.91, 95% CI 0.84 to 0.99). Using the more precise measures of cycling available from the second health assessment, all types of cycling were associated with greater total moderate-to-vigorous physical activity; however, there was little evidence of an association between overall or domain-specific cycling and mortality.

Conclusions
Cycling, in particular for utility purposes, was associated with greater moderate-to-vigorous and total physical activity. While this study provides tentative evidence that modest levels of cycling may reduce the risk of mortality, further research is required to confirm how much cycling is sufficient to induce health benefits.

N-acetylcysteine versus placebo for treating nail biting, a double blind randomized placebo controlled clinical trial

Nail biting is a common behavioral problem. While there are established behavioral interventions for management, they are of modest efficacy, and there is minimal evidence for effective pharmacotherapy. This study investigated the role of N-acetylcysteine (NAC) a potent glutathione and glutamate modulator for the treatment of pathological nail biting in children and adolescents. This pilot randomized, double-blind, placebo-controlled clinical trial of NAC (800mg/day) or placebo enrolled 42 children and adolescents with chronic nail biting. Nail length was the objective outcome. Evaluations were carried out three times; before treatment, one month after enrollment in the study, and two months after enrollment. The duration (chronicity) of nail biting in the NAC and placebo groups was 3.63(2.45) and 5.09(3.74) years (P=0.14). The mean nail length gradually increased in both the NAC and placebo groups during this trial. There was a statistically significant difference between the two groups regarding increased nail length after the first month of trial [(5.21(5.75) and 1.18(3.02) millimeters], however no difference after two months was observed. Two patients in the NAC group discontinued medication due to adverse events. One patient experienced headache, agitation, and social withdrawal, and another patient expressed severe aggression after taking medication and was withdrawn from the study. This study supports the hypothesis that NAC decreases nail biting behavior in children and adolescents over the short term. NAC is relatively well tolerated and severe adverse effects are rare. However, there was a high rate of dropout. Further studies with longer durations that build on these preliminary data are recommended.

The Supervision of Known Sex Offenders in the Community: Monitoring Progress and Providing Feedback

Case management is the process by which most known sex offenders who live in the community are currently supervised. However, by itself, case management has been shown to have only a modest impact on rates of re-offending, and it is only when case work and/or treatment sessions are introduced, that the benefits become apparent. This paper considers how routinely collecting and feeding back standardized data about client progress towards supervisory goals can be integrated into the offender supervision and case management process. Based on methods that have been shown to be associated with enhanced outcomes in mental health, it is suggested that the implementation of feedback approaches have the potential to both enhance the case management process and improve the effectiveness of those policies which require it.

Buses, cars, bicycles and walkers the influence of the type of human transport on the flight responses of waterbirds

One way to manage disturbance to waterbirds in natural areas where humans require access is to promote the occurrence of stimuli for which birds tolerate closer approaches, and so cause fewer responses. We conducted 730 experimental approaches to 39 species of waterbird, using five stimulus types (single walker, three walkers, bicycle, car and bus) selected to mimic different human management options available for a controlled access, Ramsar-listed wetland. Across species, where differences existed (56% of 25 cases), motor vehicles always evoked shorter flight-initiation distances (FID) than humans on foot. The influence of stimulus type on FID varied across four species for which enough data were available for complete cross-stimulus analysis. All four varied FID in relation to stimuli, differing in 4 to 7 of 10 possible comparisons. Where differences occurred, the effect size was generally modest, suggesting that managing stimulus type (e.g. by requiring people to use vehicles) may have species-specific, modest benefits, at least for the waterbirds we studied. However, different stimulus types have different capacities to reduce the frequency of disturbance (i.e. by carrying more people) and vary in their capacity to travel around important habitat

Influence of age and gender on fat mass, fat-free mass and skeletal muscle mass among Australian adults: the Australian diabetes, obesity and lifestyle study (AUSDIAB)

Background
Bioelectrical impedance (BIA) represents a simple, inexpensive and non-invasive method that is often used to assess fat-mass (FM) and fat-free mass (FFM) in large population-based cohorts.

Objective
The aim of this study was to describe the reference ranges and examine the influence of age and gender on FM, FFM and skeletal muscle mass (SMM) as well as height-adjusted estimates of FM [fat mass index (FMI)], FFM [fat-free mass index (FFMI)] and SMM [SMM index (SMI)] in a national, population-based cohort of Australian adults.

Design and Participants
The analytical sample included a total of 8,582 adults aged 25–91 years of Europid origin with complete data involved in the cross-sectional 1999–2000 Australian, Diabetes, Obesity and Lifestyle (AusDiab) Study.

Measurements
Bioelectrical impedance analysis was used to examine components of body composition. Demographic information was derived from a household interview.

Results
For both genders, FFM, SMM and SMI decreased linearly from the age of 25 years, with the exception that in men SMI was not related to age and FFM peaked at age 38 years before declining thereafter. The relative loss from peak values to ≥75 years in FFM (6–8%) and SMM (11–15%) was similar between men and women. For FM and FMI, there was a curvilinear relationship with age in both genders, but peak values were detected 6–7 years later in women with a similar relative loss thereafter. For FFMI there was no change with age in men and a modest increase in women.

Conclusion
In Australian adults there is heterogeneity in the age of onset, pattern and magnitude of changes in the different measures of muscle and fat mass derived from BIA, but overall the agerelated losses were similar between men and women.

Australia’s strategic culture: constraints and opportunities in security policymaking

 This article draws on fourth generation strategic culture debates to show the gap between the rhetoric of Australian defence and the more modest reality. Our analysis shows that these limits derive from tensions between national strategic culture and organizational strategic subcultures. There are serious debates in the nation regarding the preferred course of the Australian military and security policy. This article frames these debates by examining the ‘keepers’ of Australia's national strategic culture, the existence of several competing strategic subcultures, and the importance of norm entrepreneurs in changing defence and national security thinking. Strategic subcultures foster compartmentalization, constraints, and bureaucratic silos that narrow national conceptions of security threats and opportunities, and impinge on the formation of coherent foreign and defence policy in relation to the Asia-Pacific region. This analysis shows that a distinct national strategic culture and organizational strategic subcultures endure beyond individual governments, placing potential limits on Australia's interface with other Asia-Pacific strategic cultures in the future.

Exposure to a high-fat diet alters leptin sensitivity and elevates renal sympathetic nerve activity and arterial pressure in rabbits

The activation of the sympathetic nervous system through the central actions of the adipokine leptin has been suggested as a major mechanism by which obesity contributes to the development of hypertension. However, direct evidence for elevated sympathetic activity in obesity has been limited to muscle. The present study examined the renal sympathetic nerve activity and cardiovascular effects of a high-fat diet (HFD), as well as the changes in the sensitivity to intracerebroventricular leptin. New Zealand white rabbits fed a 13.5% HFD for 4 weeks showed modest weight gain but a 2- to 3-fold greater accumulation of visceral fat compared with control rabbits. Mean arterial pressure, heart rate, and plasma norepinephrine concentration increased by 8%, 26%, and 87%, respectively (P<0.05), after 3 weeks of HFD. Renal sympathetic nerve activity was 48% higher (P<0.05) in HFD compared with control diet rabbits and was correlated to plasma leptin (r=0.87; P<0.01). Intracerebroventricular leptin administration (5 to 100 μg) increased mean arterial pressure similarly in both groups, but renal sympathetic nerve activity increased more in HFD-fed rabbits. By contrast, intracerebroventricular leptin produced less neurons expressing c-Fos in HFD compared with control rabbits in regions important for appetite and sympathetic actions of leptin (arcuate: −54%, paraventricular: −69%, and dorsomedial hypothalamus: −65%). These results suggest that visceral fat accumulation through consumption of a HFD leads to marked sympathetic activation, which is related to increased responsiveness to central sympathoexcitatory effects of leptin. The paradoxical reduction in hypothalamic neuronal activation by leptin suggests a marked “selective leptin resistance” in these animals.

The impact of interventions to prevent obesity or improve obesity related behaviours in children (0-5 years) from socioeconomically disadvantaged and/or indigenous families: a systematic review

Background
Children from disadvantaged families including those from low socioeconomic backgrounds and Indigenous families have higher rates of obesity, making early intervention a priority. The aim of this study was to systematically review the literature to examine the effectiveness of interventions to prevent obesity or improve obesity related behaviours in children 0-5 years from socioeconomically disadvantaged or Indigenous families.

Methods
Searches of major electronic databases identified articles published from 1993–2013 targeting feeding practices, anthropometric, diet, activity or sedentary behaviour outcomes. This was supplemented with snowballing from existing reviews and primary studies. Data extraction was undertaken by one author and cross checked by another. Quality assessments included both internal and external validity.

Results
Thirty-two studies were identified, with only two (both low quality) in Indigenous groups. Fourteen studies had a primary aim to prevent obesity. Mean differences between intervention and control groups ranged from -0.29 kg/m2 to -0.54 kg/m2 for body mass index (BMI) and -2.9 to -25.6% for the prevalence of overweight/obesity. Interventions initiated in infancy (under two years) had a positive impact on obesity related behaviours (e.g. diet quality) but few measured the longer-term impact on healthy weight gain. Findings amongst pre-schoolers (3–5 years) were mixed, with the more successful interventions requiring high levels of parental engagement, use of behaviour change techniques, a focus on skill building and links to community resources. Less than 10% of studies were high quality. Future studies should focus on improving study quality, including follow-up of longer-term anthropometric outcomes, assessments of cost effectiveness, acceptability in target populations and potential for implementation in routine service delivery.

Conclusion
There is an urgent need for further research on effective obesity prevention interventions for Indigenous children. The findings from the growing body of intervention research focusing on obesity prevention amongst young children from socioeconomically disadvantaged families suggest intervention effects are modest but promising. Further high quality studies with longer term follow up are required.

Predicting psychological and subjective well-being from personality: incremental prediction from 30 facets over the Big 5

This study investigated the relationship between the Big 5, measured at factor and facet levels, and dimensions of both psychological and subjective well-being. Three hundred and thirty-seven participants completed the 30 Facet International Personality Item Pool Scale, Satisfaction with Life Scale, Positive and Negative Affectivity Schedule, and Ryff’s Scales of Psychological Well-Being. Cross-correlation decomposition presented a parsimonious picture of how well-being is related to personality factors. Incremental facet prediction was examined using double-adjusted r2 confidence intervals and semi-partial correlations. Incremental prediction by facets over factors ranged from almost nothing to a third more variance explained, suggesting a more modest incremental prediction than presented in the literature previously. Examination of semi-partial correlations controlling for factors revealed a small number of important facet-well-being correlations. All data and R analysis scripts are made available in an online repository.

Zn electrochemistry in 1-Ethyl-3-Methylimidazolium and N-Butyl-N-Methylpyrrolidinium Dicyanamides: promising new rechargeable Zn battery electrolytes

 We have studied both 1-ethyl-3-methylimidazolium (C2mim) and N-butyl-N-methylpyrrolidinium (C4mpyr) dicyanamide (dca) ionic liquids (ILs) containing 3 wt % H2O and 9 mol % Zn(dca)2 salt for their ability to support Zn0/2+ electrochemistry in the context of a rechargeable Zn battery. Despite the similarities of the two IL electrolyte systems [identical H2O and Zn(dca)2 contents], the system based on [C2mim] supported much higher current densities for Zn electrochemistry at greatly reduced overpotentials [−0.23 V vs. Zn pseudo-reference, 32 mA cm−2 (red) and 61 mA cm−2 (ox)] compared to the [C4mpyr]-based electrolyte [−0.84 V vs. Zn pseudo-reference, 8 mA cm−2 (red) and 15 mA cm−2 (ox)]. The overpotential for Zn deposition is reduced by 0.13 V on Zn metal surfaces compared to glassy carbon (GC), regardless of the electrolyte used. The morphologies of the Zn deposits on both GC and Zn surfaces were also studied. The Zn surfaces promote a deposition that displays a smooth morphology, resulting from an instantaneous nucleation mechanism demonstrated by chronoamperometric experiments. Finally, both [C2mim] and [C4mpyr] electrolytes were tested in symmetrical Zn|Zn cells, where it was determined that the [C2mim] system could sustain over 90 cycles at 0.1 mA cm−2, whereas the [C4mpyr] based system could only achieve 15 cycles at the more modest current density of 0.05 mA cm−2.

The systematic influences on student evaluation of teaching in engineering education

BACKGROUND Student evaluation of teaching (SET) has a long history, has grown in prevalence and importance over a period of decades, and is now common-place in many universities internationally. SET data are collected for a range of purposes, including: as diagnostic feedback to improve the quality of teaching and learning; as an input to staff performance management processes and personnel decisions such as promotion for staff; to provide information to prospective students in their selection of courses and programs; and as a source of data for research on teaching. Rovai et al. (2006) report that while SET research provides mixed results, there is evidence that, for course-related factors, smaller classes are rated more favourably than large classes, upper-year-level classes are rated more favourably than lower-year classes, and that there are rating differences between discipline areas. While additional course-related factors are also noted, other reviews of the literature on SET also identify these three factors as commonly reported systematic influences on SET ratings. The School of Engineering at Deakin University in Australia offers undergraduate and postgraduate engineering programs, and these programs are delivered in both on-campus and off-campus modes.PURPOSEThe paper presents a quantitative investigation of SET data for the School of Engineering at Deakin University to identify whether the commonly reported systematic influences on SET ratings of class size and year level are also observed here. The influence of online mode of offer is also explored.DESIGN/METHOD Deakin University’s Student Evaluation of Teaching and Units (SETU) questionnaire is administered to students enrolled in every unit of study every time that unit is offered, unless it is specially exempted. Following data collation, summary results are reported via a public website. The publicly available SETU data for all School of Engineering units of study were collected for a two year period. The collected data were subjected to analysis of variance (ANOVA) analysis to identify any significant systematic influences on mean student SETU ratings.RESULTS SETU data from 100 separate units of study over the two year period were collected, representing 3375 sets of SETU ratings, and covering unit enrolment sizes from 12 to 462 students. Although this was a modest sized investigation, significantly higher mean ratings for some SETU items were observed for units with small enrolments, for postgraduate level units compared to undergraduate level units, and for units offered in conventional mode compared to online mode of offer. The presence of the commonly observed systematic influences on SET ratings was confirmed.CONCLUSIONS While the use of SET data may have originally been primarily for formative purposes to improve teaching and learning, they are also increasingly used for summative judgements of teaching quality and teaching staff performance that have implications for personnel decision making. There may be an acceptance of the need for SET, however there remains no universal consensus as to what constitutes quality in university teaching and learning, and the increasing use of SET for high-stakes decision making puts pressure on institutions to ensure that their SET practices are sound, equitable and defensible.

Current state of China tourism research

Along with the tremendous growth of tourism development in China after its successful hosting of two international mega-events (i.e. the 2010 Shanghai World Expo and the 2010 Guangzhou Asian Games), a modest body of academic research on tourism in China has been developed since the start of the second decade of the new millennium. To supplement the continuous development of China's tourism industry, this study presents a review of 147 research articles from tourism journals during the period 2010-2012. Through content analysis, the empirical findings indicate that tourist behaviour and experience was the most researched theme, followed by culture and heritage studies. The trend of research collaboration, particularly international collaboration, was evident among the analysed studies. This study also presents the diversity in recent research in the realm of tourism in China in terms of research context, geographical coverage, data collection and analysis method, and institutional contribution.