987 resultados para Malfilâtre, 1733-1767.


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Este texto inventaria os grandes desafios da escolarização dos alunos em situação de deficiência, em França e na Europa, nos domínios do direito, dos media, dos conceitos, das estruturas, dos meios de acompanhamento, dos percursos escolares, dos cursos universitários e da formação de professores. Em cada um dos campos, formula o problema e faz uma proposta de acção. O ponto comum de todas as propostas é apoiar-se na ideia de continuum de acção e de pensamento, em oposição à ruptura e fragmentação, para responder ao continuum de diversidade dos alunos ao qual a Escola, aqui e lá, tem hoje de responder.

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El trabajo analiza la interpretación y aplicación de los tratados internacionales en materia tributaria así como lo atinente a su abusiva utilización. Para cumplir con el primer propósito examina las normas generales sobre la interpretación de los tratados de la Convención de Viena de 1969 a la cual adhirió el país en 2003. El aporte principal radica en el señalamiento y comentario de las disposiciones de la Convención que son aplicables para la interpretación de las convenciones tributarias internacionales y particularmente a las que se suscriben a fin de evitar la doble imposición. Para cumplir con el segundo analiza los casos en que los sujetos se aprovechan de los beneficios de los convenios sin que los mismos les sean aplicables. Singularmente alude a los denominados treaty shopping y a los comentarios de la OCDE sobre este tema.

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Presenta las reseñas de los libros: Jaime Breilh Paz y Miño y Fanny Herrera, El proceso juliano. Pensamiento, utopía y militares solidarios, Quito, Corporación Editora Nacional/Universidad Andina Simón Bolívar, Sede Ecuador, 2011, 200 pp. -- Roberto Choque Canqui y Cristina Quisbert Quispe, Historia de una lucha desigual. Los contenidos ideológicos y políticos de las rebeliones indígenas de la pre y post revolución nacional, La Paz, Unidad de Investigaciones Históricas Unih-Pakaxa, 2012, 259 pp . -- Guadalupe Soasti Toscano, comp., Política, participación y ciudadanía en el proceso de independencia en la América Andina, Quito, Fundación Konrad Adenauer, 2008, 348 pp. -- Nicholas Cushner, Hacienda y obraje, los jesuitas y el inicio del capitalismo agrario en Quito colonial, 1600-1767, traducción de Gonzalo Ortiz Crespo, Biblioteca Básica de Quito, Instituto Metropolitano de Patrimonio, Quito, 2012, 399 pp.

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We discuss and test the potential usefulness of single-column models (SCMs) for the testing of stochastic physics schemes that have been proposed for use in general circulation models (GCMs). We argue that although single column tests cannot be definitive in exposing the full behaviour of a stochastic method in the full GCM, and although there are differences between SCM testing of deterministic and stochastic methods, SCM testing remains a useful tool. It is necessary to consider an ensemble of SCM runs produced by the stochastic method. These can be usefully compared to deterministic ensembles describing initial condition uncertainty and also to combinations of these (with structural model changes) into poor man's ensembles. The proposed methodology is demonstrated using an SCM experiment recently developed by the GCSS (GEWEX Cloud System Study) community, simulating transitions between active and suppressed periods of tropical convection.

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Despite the many models developed for phosphorus concentration prediction at differing spatial and temporal scales, there has been little effort to quantify uncertainty in their predictions. Model prediction uncertainty quantification is desirable, for informed decision-making in river-systems management. An uncertainty analysis of the process-based model, integrated catchment model of phosphorus (INCA-P), within the generalised likelihood uncertainty estimation (GLUE) framework is presented. The framework is applied to the Lugg catchment (1,077 km2), a River Wye tributary, on the England–Wales border. Daily discharge and monthly phosphorus (total reactive and total), for a limited number of reaches, are used to initially assess uncertainty and sensitivity of 44 model parameters, identified as being most important for discharge and phosphorus predictions. This study demonstrates that parameter homogeneity assumptions (spatial heterogeneity is treated as land use type fractional areas) can achieve higher model fits, than a previous expertly calibrated parameter set. The model is capable of reproducing the hydrology, but a threshold Nash-Sutcliffe co-efficient of determination (E or R 2) of 0.3 is not achieved when simulating observed total phosphorus (TP) data in the upland reaches or total reactive phosphorus (TRP) in any reach. Despite this, the model reproduces the general dynamics of TP and TRP, in point source dominated lower reaches. This paper discusses why this application of INCA-P fails to find any parameter sets, which simultaneously describe all observed data acceptably. The discussion focuses on uncertainty of readily available input data, and whether such process-based models should be used when there isn’t sufficient data to support the many parameters.

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A determination key to the Central European paper wasps (Polistinae – Polistes Latreille, 1802 – eight species) and social wasps (Vespinae – 11 species: Vespa Linnaeus, 1758 – one species, Vespula Thomson, 1869 – four species, Dolichovespula Rohwer, 1916 – six species) is given. Distribution and biotope requirements of all species in the Czech Republic and Slovakia are briefly mentioned. All social wasps occur more or less regularly in both countries. Four paper wasps are relatively common but four other species (Polistes atrimandibularis Zimmermann, 1930, P. sulcifer Zimmermann, 1930, P. associus Kohl, 1898, and P. gallicus (Linnaeus, 1767)) are very rare with the Czech Republic and/or Slovakia at the northern edge of their range.

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BACKGROUND: Trophoblast invasion is a temporally and spatially regulated scheme of events that can dictate pregnancy outcome. Evidence suggests that the potent mitogen epidermal growth factor (EGF) regulates cytotrophoblast (CTB) differentiation and invasion during early pregnancy. METHODS AND RESULTS: In the present study, the first trimester extravillous CTB cell line SGHPL-4 was used to investigate the signalling pathways involved in the motile component of EGF-mediated CTB migration/invasion. EGF induced the phosphorylation of the phosphatidylinositol 3-kinase (PI3-K)-dependent proteins, Akt and GSK-3β as well as both p42/44 MAPK and p38 mitogen-activated protein kinases (MAPK). EGF-stimulated motility was significantly reduced following the inhibition of PI3-K (P < 0.001), Akt (P < 0.01) and both p42/44 MAPK (P < 0.001) and p38 MAPKs (P < 0.001) but not the inhibition of GSK-3β. Further analysis indicated that the p38 MAPK inhibitor SB 203580 inhibited EGF-stimulated phosphorylation of Akt on serine 473, which may be responsible for the effect SB 203580 has on CTB motility. Although Akt activation leads to GSK-3β phosphorylation and the subsequent expression of β-catenin, activation of this pathway by 1-azakenpaullone was insufficient to stimulate the motile phenotype. CONCLUSION: We demonstrate a role for PI3-K, p42/44 MAPK and p38 MAPK in the stimulation of CTB cell motility by EGF, however activation of β-catenin alone was insufficient to stimulate cell motility.

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Diploid Fragaria provide a potential model for genomic studies in the Rosaceae. To develop a genetic linkage map of diploid Fragaria, we scored 78 markers (68 microsatellites, one sequence-characterised amplified region, six gene-specific markers and three morphological traits) in an interspecific F2 population of 94 plants generated from a cross of F.vesca f. semperflorens × F. nubicola. Co-segregation analysis arranged 76 markers into seven discrete linkage groups covering 448 cM, with linkage group sizes ranging from 100.3 cM to 22.9 cM. Marker coverage was generally good; however some clustering of markers was observed on six of the seven linkage groups. Segregation distortion was observed at a high proportion of loci (54%), which could reflect the interspecific nature of the progeny and, in some cases, the self-incompatibility of F. nubicola. Such distortion may also account for some of the marker clustering observed in the map. One of the morphological markers, pale-green leaf (pg) has not previously been mapped in Fragaria and was located to the mid-point of linkage group VI. The transferable nature of the markers used in this study means that the map will be ideal for use as a framework for additional marker incorporation aimed at enhancing and resolving map coverage of the diploid Fragaria genome. The map also provides a sound basis for linkage map transfer to the cultivated octoploid strawberry.

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MPJ Express is our implementation of MPI-like bindings for Java. In this paper we discuss our intermediate buffering layer that makes use of the so-called direct byte buffers introduced in the Java New I/O package. The purpose of this layer is to support the implementation of derived datatypes. MPJ Express is the first Java messaging library that implements this feature using pure Java. In addition, this buffering layer allows efficient implementation of communication devices based on proprietary networks such as Myrinet. In this paper we evaluate the performance of our buffering layer and demonstrate the usefulness of direct byte buffers. Also, we evaluate the performance of MPJ Express against other messaging systems using Myrinet and show that our buffering layer has made it possible to avoid the overheads suffered by other Java systems such as mpiJava that relies on the Java Native Interface.

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MPJ Express is our implementation of MPI-like bindings for Java. In this paper we discuss our intermediate buffering layer that makes use of the so-called direct byte buffers introduced in the Java New I/O package. The purpose of this layer is to support the implementation of derived datatypes. MPJ Express is the first Java messaging library that implements this feature using pure Java. In addition, this buffering layer allows efficient implementation of communication devices based on proprietary networks such as Myrinet. In this paper we evaluate the performance of our buffering layer and demonstrate the usefulness of direct byte buffers. Also, we evaluate the performance of MPJ Express against other messaging systems using Myrinet and show that our buffering layer has made it possible to avoid the overheads suffered by other Java systems such as mpiJava that relies on the Java Native Interface.

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How can a bridge be built between autonomic computing approaches and parallel computing systems? The work reported in this paper is motivated towards bridging this gap by proposing a swarm-array computing approach based on ‘Intelligent Agents’ to achieve autonomy for distributed parallel computing systems. In the proposed approach, a task to be executed on parallel computing cores is carried onto a computing core by carrier agents that can seamlessly transfer between processing cores in the event of a predicted failure. The cognitive capabilities of the carrier agents on a parallel processing core serves in achieving the self-ware objectives of autonomic computing, hence applying autonomic computing concepts for the benefit of parallel computing systems. The feasibility of the proposed approach is validated by simulation studies using a multi-agent simulator on an FPGA (Field-Programmable Gate Array) and experimental studies using MPI (Message Passing Interface) on a computer cluster. Preliminary results confirm that applying autonomic computing principles to parallel computing systems is beneficial.

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A series of scale model measurements of transverse electromagnetic mode tapered slot antennas are presented. They show that the beam launched by this type of antenna is astigmatic. It is shown how an off-axis spherical mirror can be used to correct this astigmatism to allow efficient coupling to quasi-optical systems. A millimetre wave antenna and mirror combination is described and, with the aid of solid state noise diodes, the coupling of the launched beam to a quasi-optical spectrometer is shown to be in good agreement with that predicted by the scale model measurements.