Immunization protected well nourished mice but not undernourished ones from lung injury in Methicillin-resistant Staphylococcus aureus (MRSA) infection

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Morphological changes in distant muscle fibers following thermal injury in Wistar rats

Purpose: Thermal injury causes catabolic processes as the body attempts to repair the damaged area. This study evaluated the effects of a scald injury on the morphology of muscle fibers belonging to a muscle distant from the lesion. Methods: Thirty Wistar rats were divided into control (C) and scalded (S) groups. Group S was scalded over 45% of the body surface, standardized by body weight. Rats in both groups were euthanized at four, seven and 14 days following the injury. The middle portions of the medial gastrocnemius muscles were sectioned, stained with hematoxylin and eosin and Picrosirius, and submitted to histological analysis. Results: Control group sections exhibited equidistantly distributed polygonal muscle fibers with peripheral nuclei, characteristic of normal muscle. The injured group sections did not consistently show these characteristics; many fibers in these sections exhibited a rounded contour, variable stain intensities, and greater interfiber distances. A substantially increased amount of connective tissue was also observed on the injured group sections. Conclusion: This experimental model found a morphological change in muscle distant from the site of thermal injury covering 45% of the body surface.

The Effects of a 785-nm AlGaInP Laser on the Regeneration of Rat Anterior Tibialis Muscle After Surgically-Induced Injury

Objective: This study aims to investigate the effects of low-level laser therapy (LLLT) on muscle regeneration. For this purpose, the anterior tibialis muscle of 48 male Wistar rats received AlGaInP laser treatment (785 nm) after surgically-induced injury.Background Data: Few studies have been conducted on the effects of LLLT on muscle regeneration at different irradiation doses.Materials and Methods: The animals were randomized into four groups: uninjured rats (UN); uninjured and laser-irradiated rats (ULI); injured rats (IN); and injured and laser-irradiated rats (ILI). The direct contact laser treatment was started 24 h after surgery. An AlGaInP diode laser emitting 75 mW of continuous power at 785 nm was used for irradiation. The laser probe was placed at three treatment points to deliver 0.9 J per point, for a total dose of 2.7 J per treatment session. The animals were euthanized after treatment sessions 1, 2, and 4. Mounted sections were stained with hematoxylin and eosin and used for quantitative morphological analysis, in which the number of leukocytes and fibroblasts were counted over an area of 4480 mu m(2). The data were statistically analyzed by analysis of variance (ANOVA) and the Bonferroni t-test.Results: Quantitative data showed that the number of both polymorphonuclear and mononuclear leukocytes in the inflammatory infiltrate at the injury site was smaller in the ILI(1), ILI(2), and ILI(4) subgroups compared with their respective control subgroups (IN(1), IN(2), and IN(4)) for sessions 1, 2, and 4, respectively (p < 0.05). on the other hand, the number of fibroblasts increased after the fourth treatment session (p < 0.05). With regard to the regeneration of muscle fibers following injury, only after the fourth treatment session was it possible to find muscle precursor cells such as myoblasts and some myotubes in the ILI(4) subgroup.Conclusion: During the acute inflammatory phase, the AlGaInP laser treatment was found to have anti-inflammatory effects, reducing the number of leukocytes at the injury site and accelerating the regeneration of connective tissue.

Fructose-rich diet leads to reduced aerobic capacity and to liver injury in rats

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Annexin 1 mimetic peptide protects against renal ischemia/reperfusion injury in rats

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Nonlinear Lattice Within Supersymmetric Quantum Mechanics Formalism

In the last decades, the study of nonlinear one dimensional lattices has attracted much attention of the scientific community. One of these lattices is related to a simplified model for the DNA molecule, allowing to recover experimental results, such as the denaturation of DNA double helix. Inspired by this model we construct a Hamiltonian for a reflectionless potential through the Supersymmetric Quantum Mechanics formalism, SQM. Thermodynamical properties of such one dimensional lattice are evaluated aming possible biological applications.

A mass-transportation approach to a one dimensional fluid mechanics model with nonlocal velocity

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Zel'dovich's method of perturbation theory in quantum mechanics

Many years ago Zel'dovich showed how the Lagrange condition in the theory of differential equations can be utilized in the perturbation theory of quantum mechanics. Zel'dovich's method enables us to circumvent the summation over intermediate states. As compared with other similar methods, in particular the logarithmic perturbation expansion method, we emphasize that this relatively unknown method of Zel'dovich has a remarkable advantage in dealing with excited stares. That is, the ground and excited states can all be treated in the same way. The nodes of the unperturbed wavefunction do not give rise to any complication.

Time-reversal aspect of the point interactions in one-dimensional quantum mechanics

It is known that there is a four-parameter family of point interactions in one-dimensional quantum mechanics. We point out that, as far as physics is concerned, it is sufficient to use three of the four parameters. The fourth parameter is redundant. The apparent violation of time-reversal invariance in the presence of the fourth parameter is an artifact.

Renormalization group invariance of quantum mechanics

We propose a framework to renormalize the nonrelativistic quantum mechanics with arbitrary singular interactions. The scattering equation is written to have one or more subtraction in the kernel at a given energy scale. The scattering amplitude is the solution of a nth order derivative equation in respect to the renormalization scale, which is the nonrelativistic counterpart of the Callan-Symanzik formalism, Scaled running potentials for the subtracted equations keep the physics invariant fur a sliding subtraction point. An example of a singular potential, that requires more than one subtraction to renormalize the theory is shown. (C) 2000 Published by Elsevier B.V. B.V. All rights reserved.

Variational Formulation for Quaternionic Quantum Mechanics

A quaternionic version of Quantum Mechanics is constructed using the Schwinger's formulation based on measurements and a Variational Principle. Commutation relations and evolution equations are provided, and the results are compared with other formulations.

Pseudoclassical mechanics for the spin-0 and -1 particles

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Quantum mechanics versus equivalence principle

We consider the scattering of a photon by a weak gravitational field, treated as an external field, up to second order of the perturbation expansion. The resulting cross section is energy dependent which indicates a violation of Galileo's equivalence principle (universality of free fall) and, consequently, of the classical equivalence principle. The deflection angle theta for a photon passing by the sun is evaluated afterward and the likelihood of detecting Delta theta/theta(E) theta-theta(E)/theta(E) (where theta(E) is the value predicted by Einstein's geometrical theory for the light bending) in the foreseeable future, is discussed.

Can quantum mechanics fool the cosmic censor?

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)