Resistance Training After Myocardial Infarction in Rats: Its Role on Cardiac and Autonomic Function

Background: Although resistance exercise training is part of cardiovascular rehabilitation programs, little is known about its role on the cardiac and autonomic function after myocardial infarction. Objective: To evaluate the effects of resistance exercise training, started early after myocardial infarction, on cardiac function, hemodynamic profile, and autonomic modulation in rats. Methods: Male Wistar rats were divided into four groups: sedentary control, trained control, sedentary infarcted and trained infarcted rats. Each group with n = 9 rats. The animals underwent maximum load test and echocardiography at the beginning and at the end of the resistance exercise training (in an adapted ladder, 40% to 60% of the maximum load test, 3 months, 5 days/week). At the end, hemodynamic, baroreflex sensitivity and autonomic modulation assessments were made. Results: The maximum load test increased in groups trained control (+32%) and trained infarcted (+46%) in relation to groups sedentary control and sedentary infarcted. Although no change occurred regarding the myocardial infarction size and systolic function, the E/A ratio (-23%), myocardial performance index (-39%) and systolic blood pressure (+6%) improved with resistance exercise training in group trained infarcted. Concomitantly, the training provided additional benefits in the high frequency bands of the pulse interval (+45%), as well as in the low frequency band of systolic blood pressure (-46%) in rats from group trained infarcted in relation to group sedentary infarcted. Conclusion: Resistance exercise training alone may be an important and safe tool in the management of patients after myocardial infarction, considering that it does not lead to significant changes in the ventricular function, reduces the global cardiac stress, and significantly improves the vascular and cardiac autonomic modulation in infarcted rats.

Florula bostoniensis. A collection of plants of Boston and its vicinity, with their generic and specific characters, principal synonyms, descriptions, places of growth, and time of flowering, and occasional remarks. By Jacob Bigelow ...

2nd ed.

The animal kingdom arranged in conformity with its organization / by the Baron Cuvier ; the Crustacea, Arachnides and Insecta, by P.A. Latreille ; translated from the French, with notes and additions, by H. M'Murtrie ; in four volumes, with plates.

v 1 (1831)

Florula bostoniensis. A collection of plants of Boston and its environs, with their generic and specific characters, synonyms, descriptions, places of growth, and time of flowering, and occasional remarks.

1st ed.

One-year Mortality after an Acute Coronary Event and its Clinical Predictors: The ERICO Study

Background:Information about post-acute coronary syndrome (ACS) survival have been mostly short-term findings or based on specialized, cardiology referral centers.Objectives:To describe one-year case-fatality rates in the Strategy of Registry of Acute Coronary Syndrome (ERICO) cohort, and to study baseline characteristics as predictors.Methods:We analyzed data from 964 ERICO participants enrolled from February 2009 to December 2012. We assessed vital status by telephone contact and official death certificate searches. The cause of death was determined according to the official death certificates. We used log-rank tests to compare the probabilities of survival across subgroups. We built crude and adjusted (for age, sex and ACS subtype) Cox regression models to study if the ACS subtype or baseline characteristics were independent predictors of all-cause or cardiovascular mortality.Results:We identified 110 deaths in the cohort (case-fatality rate, 12.0%). Age [Hazard ratio (HR) = 2.04 per 10 year increase; 95% confidence interval (95%CI) = 1.75–2.38], non-ST elevation myocardial infarction (HR = 3.82 ; 95%CI = 2.21–6.60) or ST elevation myocardial infarction (HR = 2.59; 95%CI = 1.38–4.89) diagnoses, and diabetes (HR = 1.78; 95%CI = 1.20‑2.63) were significant risk factors for all-cause mortality in the adjusted models. We found similar results for cardiovascular mortality. A previous coronary artery disease diagnosis was also an independent predictor of all-cause mortality (HR = 1.61; 95%CI = 1.04–2.50), but not for cardiovascular mortality.Conclusion:We found an overall one-year mortality rate of 12.0% in a sample of post-ACS patients in a community, non-specialized hospital in São Paulo, Brazil. Age, ACS subtype, and diabetes were independent predictors of poor one‑year survival for overall and cardiovascular-related causes.

Biochemical and functional characterization of Fyn-PAG association and its role in T-cell anergy

T-cell anergy, adaptor proteins, T-cell signaling

Zoology of New York; or, The New York Fauna; comprising detailed descriptions of all the animals hitherto observed within the state of New York, with brief notices of those occasionally found near its borders, and accompanied by appropriate illustrations /

Introduction

Zoology of New York; or, The New York Fauna; comprising detailed descriptions of all the animals hitherto observed within the state of New York, with brief notices of those occasionally found near its borders, and accompanied by appropriate illustrations /

Part 2, Birds

Zoology of New York; or, The New York Fauna; comprising detailed descriptions of all the animals hitherto observed within the state of New York, with brief notices of those occasionally found near its borders, and accompanied by appropriate illustrations /

Part 3, Reptiles-Text

Zoology of New York; or, The New York Fauna; comprising detailed descriptions of all the animals hitherto observed within the state of New York, with brief notices of those occasionally found near its borders, and accompanied by appropriate illustrations /

Part 4, Fishes-Plates

Zoology of New York; or, The New York Fauna; comprising detailed descriptions of all the animals hitherto observed within the state of New York, with brief notices of those occasionally found near its borders, and accompanied by appropriate illustrations /

Part 3, Reptiles-Plates

Zoology of New York; or, The New York Fauna; comprising detailed descriptions of all the animals hitherto observed within the state of New York, with brief notices of those occasionally found near its borders, and accompanied by appropriate illustrations /

Part 1, Mammalia

Zoology of New York; or, The New York Fauna; comprising detailed descriptions of all the animals hitherto observed within the state of New York, with brief notices of those occasionally found near its borders, and accompanied by appropriate illustrations /

Part 6, Crustacea

Zoology of New York; or, The New York Fauna; comprising detailed descriptions of all the animals hitherto observed within the state of New York, with brief notices of those occasionally found near its borders, and accompanied by appropriate illustrations /

Part 4, Fishes-Text