Alterações na flora espontânea em sistemas agroecológicos de produção de café.

2014

Cultivo consorciado de café com bananeira em bases agroecológicas reduz a incidência de plantas espontâneas.

2014

Uso de resíduos da indústria de papel e celulose em plantios florestais: aspectos técnicos e legais.

Introdução; Principais resíduos sólidos e semi-sólidos gerados em complexos integrados de celulose e papel; Aspectos técnicos e legais voltados à elaboração de projeto agronômico para uso de resíduos em plantios florestais; Caracterização e classificação dos resíduos quanto aos seus riscos potenciais ao meio ambiente e à saúde pública; Caracterização de resíduos sob o aspecto agronômico; Critérios para definição de doses, épocas e formas de aplicação; Avaliação de problemas de ordem ambiental; Avaliação da viabilidade econômica; Seleção e caracterização das áreas de aplicação; Monitoramento agronômico e ambiental da área de aplicação; Manuseio, transporte e armazenamento; Processos adicionais de tratamento.

Infestação da broca-do-café e do bicho mineiro em lavoura cafeeira orgânica conduzida em sistema agroflorestal.

2009

Infestação da broca-do-café em agroecossistemas convencional, organo-mineral e orgânico na região sul de Minas Gerais.

2009

Ecogenômica de archaea e monitoramento de comunidades de procariotos redutores de sulfato: aplicações na indústria de petróleo e gás

The human activities responsible for the ambient degradation in the modern world are diverse. The industrial activities are preponderant in the question of the impact consequences for brazilian ecosystems. Amongst the human activities, the petroliferous industry in operation in Potiguar Petroliferous Basin (PPB) displays the constant risk of ambient impacts in the integrant cities, not only for the human populations and the environment, but also it reaches the native microorganisms of Caatinga ground and in the mangrove sediment. Not hindering, the elaboration of strategies of bioremediation for impacted areas pass through the knowledge of microbiota and its relations with the environment. Moreover, in the microorganism groups associated to oil, are emphasized the sulfate-reducing prokaryotes (SRP) that, in its anaerobic metabolism, these organisms participate of the sulfate reduction, discharging H2S, causing ambient risks and causing the corrosion of surfaces, as pipelines and tanks, resulting in damages for the industry. Some ancestries of PRS integrate the Archaea domain, group of microorganisms whose sequenced genomes present predominance of extremophilic adaptations, including surrounding with oil presence. This work has two correlated objectives: i) the detection and monitoring of the gene dsrB, gift in sulfate-reducing prokaryotes, through DGGE analysis in samples of mDNA of a mangrove sediment and semiarid soil, both in the BPP; ii) to relate genomic characteristics to the ecological aspects of Archaea through in silico studies, standing out the importance to the oil and gas industry. The results of the first work suggest that the petrodegraders communities of SRP persist after the contamination with oil in mangrove sediment and in semiarid soil. Comparing the populations of both sites, it reveals that there are variations in the size and composition during one year of experiments. In the second work, functional and structural factors are the probable cause to the pressure in maintenance of the conservation of the sequences in the multiple copies of the 16S rDNA gene. Is verified also the discrepancy established between total content GC and content GC of the same gene. Such results relating ribosomal genes and the ambient factors are important for metagenomic evaluations using PCR-DGGE. The knowledge of microbiota associated to the oil can contribute for a better destination of resources by the petroliferous industry and the development of bioremediation strategies. Likewise, search to lead to the best agreement of the performance of native microbiota in biogeochemical cycles in Potiguar Petroliferous Basin ecosystem

Perfil sensorial de misturas de café com leite em pó e sua aceitabilidade e preferência na Região Nordeste.

2015

DEGRADACION DE RECURSOS, POBREZA Y SALUD EN EL CANTON DE PURISCAL (I PARTE)

Se analiza de que forma la degradación de los recursos naturales conduce a través de un proceso histórico, motivado por la expulsión de la población sobrante que no pudo aprovecharse de las tierras en el área central del país, emigrar a la periferia de la Depresión Central, en el caso que nos ocupa al cantón de Puriscal, en busca de tierras para expandir el cultivo de café, granos básicos, ganadería extensiva y más recientemente al cultivo del tabaco. Las condiciones naturales del suelo imperantes en el área, los materiales muy frágiles, la fuerte pendiente unida a las prácticas agrícolas y ganaderas no acordes con la productividad agropecuaria. La penetración de empresas de la agroindustria de los lácteos, destruyo la producción campesina de la leche, y la poca productividad de la actividad tabacalera sucumbió por la importación del tabaco. Los bajos precios del café y la crítica situación de los granos básicos, provocaron un proceso de empobrecimiento de la población, que se manifiesta en tasas de migración neta negativas, desde el censo de 1950 hasta el presente. El proceso de empobrecimiento de la población es notable como consecuencias de lo interior y se manifiesta por los indicadores que en la investigación se analizan. Paralelamente el deterioro de los aspectos socioeconómicos, la investigación revela un deterioro en los niveles de salud, entendida como una condición donde intervienen aspectos de carácter físico, cultural, socioeconómico, psicológico y ambiental. La investigación analiza la distribución espacial del comportamiento de algunas enfermedades, mediante, la utilización del Sistema de Información Geográfica IDRISI. Por último, se analiza el papel del Estado a través de las políticas de salud tendentes a contrarrestar el impacto de la morbilidad y mortalidad.

Aspectos territoriais da produção e distribuição do café no Espírito Santo.

O café é um produto de relevância histórica no Brasil e mantém posição de destaque em relação à produção mundial. Em 2013, o país foi responsável por 34% do total produzido no mundo (segundo dados da Conab) e o Espírito Santo, com cerca de 700 mil toneladas (24%), foi o segundo maior produtor nacional e liderou a produção do café conilon (76%). Nosso objetivo neste estudo foi caracterizar territorialmente a produção do café nesse estado a partir de uma análise integrada de dados. Dos 78 municípios capixabas, apenas 2 não produzem café (Vitória e Marataízes) e 28 contribuem com 75% do total produzido (Pesquisa Agropecuária Municipal/IBGE). Observa-se uma regionalização da produção: as áreas cultivadas com café conilon concentram-se no norte e a produção de café arábica concentra-se no sul do estado, em regiões com altitude superior a 400 m. A importância do café para o estado também foi retratada em termos econômicos. Dos 53 produtos da agropecuária analisados na média trienal 2006-2008, o café contribuiu, sozinho, com 47% do valor total da produção. Considerando apenas o valor total de produção de café (R$ 2,7 bilhões), a variedade conilon contribuiu, em 2013, com 70% frente aos 30% do café arábica. O café apresenta fluxos de escoamento distintos, embora o principal destino seja Vitória. Outro destino recorrente de conilon é Colatina (ES), onde há grande oferta de armazenagem. Já os produtores de arábica escoam uma parte significativa de sua produção para Minas Gerais, principal centro produtor de café do Brasil atualmente.

QUESTÃO AMBIENTAL NA EDUCAÇÃO BÁSICA: PRIMEIRAS CONSIDERAÇÕES SOBRE A INDÚSTRIA DA CARNE

A problemática ambiental na educação básica perpassa várias questões. Neste artigo serão tratadas as pertinentes à qualidade de vida nas áreas urbana e rural em relação ao consumo de alimentos, sendo mais específico em relação à carne animal. Pergunta-se aqui o que se ensina e aprende na escola sobre alimentação? Será a relação de uso e descarte? No qual o que é objeto de desejo vira primeiramente mercadoria para consumo e posteriormente rejeito? Nas ruas as pessoas compram lanches rápidos, comem rapidamente e depois jogam resíduos no chão, sujando suas próprias vias de locação. Quem vai limpar, ou para onde vai esse lixo não são preocupações da maioria. E o que se faz com as sobras de comida? No Brasil, 60% do lixo domiciliar é composto por alimentos, e a cada ano, 26,3 milhões de toneladas são desperdiçados. Mas o que as pessoas estão comendo? Será que sabem de que é feito o hambúrguer? Ou a salsicha, e a margarina? Que bicho é o “Chester”? Essa é uma das tradições de consumo que se perpetua na Escola. Com certeza a Geografia tem muito a contribuir neste debate.

Definizione di uno strumento di integrazione per l’ufficio acquisti durante una fase di M&A: il caso Comer Industries e Walterscheid

Sviluppo di uno strumento di integrazione per i fornitori delle aziende Comer Industries e Walterscheid Powertrain Group. Il modello proposto è composto dalle schede di Vendor Rating e dalla matrice di Kraljic, da utilizzare nelle medesime modalità in tutto il gruppo. Prima dello sviluppo dei nuovi tool vengono presentate le precedenti versioni.

An Isoflavone From Dipteryx Alata Vogel Is Active Against The In Vitro Neuromuscular Paralysis Of Bothrops Jararacussu Snake Venom And Bothropstoxin I, And Prevents Venom-induced Myonecrosis.

Snakebite is a neglected disease and serious health problem in Brazil, with most bites being caused by snakes of the genus Bothrops. Although serum therapy is the primary treatment for systemic envenomation, it is generally ineffective in neutralizing the local effects of these venoms. In this work, we examined the ability of 7,8,3'-trihydroxy-4'-methoxyisoflavone (TM), an isoflavone from Dipteryx alata, to neutralize the neurotoxicity (in mouse phrenic nerve-diaphragm preparations) and myotoxicity (assessed by light microscopy) of Bothrops jararacussu snake venom in vitro. The toxicity of TM was assessed using the Salmonella microsome assay (Ames test). Incubation with TM alone (200 μg/mL) did not alter the muscle twitch tension whereas incubation with venom (40 μg/mL) caused irreversible paralysis. Preincubation of TM (200 μg/mL) with venom attenuated the venom-induced neuromuscular blockade by 84% ± 5% (mean ± SEM; n = 4). The neuromuscular blockade caused by bothropstoxin-I (BthTX-I), the major myotoxic PLA2 of this venom, was also attenuated by TM. Histological analysis of diaphragm muscle incubated with TM showed that most fibers were preserved (only 9.2% ± 1.7% were damaged; n = 4) compared to venom alone (50.3% ± 5.4% of fibers damaged; n = 3), and preincubation of TM with venom significantly attenuated the venom-induced damage (only 17% ± 3.4% of fibers damaged; n = 3; p < 0.05 compared to venom alone). TM showed no mutagenicity in the Ames test using Salmonella strains TA98 and TA97a with (+S9) and without (-S9) metabolic activation. These findings indicate that TM is a potentially useful compound for antagonizing the neuromuscular effects (neurotoxicity and myotoxicity) of B. jararacussu venom.

Nebivolol Reduces Central Blood Pressure In Stage I Hypertensive Patients: Experimental Single Cohort Study.

Assessment of central blood pressure (BP) has grown substantially over recent years because evidence has shown that central BP is more relevant to cardiovascular outcomes than peripheral BP. Thus, different classes of antihypertensive drugs have different effects on central BP despite similar reductions in brachial BP. The aim of this study was to investigate the effect of nebivolol, a β-blocker with vasodilator properties, on the biochemical and hemodynamic parameters of hypertensive patients. Experimental single cohort study conducted in the outpatient clinic of a university hospital. Twenty-six patients were recruited. All of them underwent biochemical and hemodynamic evaluation (BP, heart rate (HR), central BP and augmentation index) before and after 3 months of using nebivolol. 88.5% of the patients were male; their mean age was 49.7 ± 9.3 years and most of them were overweight (29.6 ± 3.1 kg/m2) with large abdominal waist (102.1 ± 7.2 cm). There were significant decreases in peripheral systolic BP (P = 0.0020), diastolic BP (P = 0.0049), HR (P < 0.0001) and central BP (129.9 ± 12.3 versus 122.3 ± 10.3 mmHg; P = 0.0083) after treatment, in comparison with the baseline values. There was no statistical difference in the augmentation index or in the biochemical parameters, from before to after the treatment. Nebivolol use seems to be associated with significant reduction of central BP in stage I hypertensive patients, in addition to reductions in brachial systolic and diastolic BP.

Predictive Value Of Phase I Trials For Safety In Later Trials And Final Approved Dose: Analysis Of 61 Approved Cancer Drugs.

Phase I trials use a small number of patients to define a maximum tolerated dose (MTD) and the safety of new agents. We compared data from phase I and registration trials to determine whether early trials predicted later safety and final dose. We searched the U.S. Food and Drug Administration (FDA) website for drugs approved in nonpediatric cancers (January 1990-October 2012). The recommended phase II dose (R2PD) and toxicities from phase I were compared with doses and safety in later trials. In 62 of 85 (73%) matched trials, the dose from the later trial was within 20% of the RP2D. In a multivariable analysis, phase I trials of targeted agents were less predictive of the final approved dose (OR, 0.2 for adopting ± 20% of the RP2D for targeted vs. other classes; P = 0.025). Of the 530 clinically relevant toxicities in later trials, 70% (n = 374) were described in phase I. A significant relationship (P = 0.0032) between increasing the number of patients in phase I (up to 60) and the ability to describe future clinically relevant toxicities was observed. Among 28,505 patients in later trials, the death rate that was related to drug was 1.41%. In conclusion, dosing based on phase I trials was associated with a low toxicity-related death rate in later trials. The ability to predict relevant toxicities correlates with the number of patients on the initial phase I trial. The final dose approved was within 20% of the RP2D in 73% of assessed trials.

Pyrimidine-5'-nucleotidase Campinas, A New Mutation (p.r56g) In The Nt5c3 Gene Associated With Pyrimidine-5'-nucleotidase Type I Deficiency And Influence Of Gilbert's Syndrome On Clinical Expression.

Pyrimidine-5'-nucleotidase type I (P5'NI) deficiency is an autosomal recessive condition that causes nonspherocytic hemolytic anemia, characterized by marked basophilic stippling and pyrimidine nucleotide accumulation in erythrocytes. We herein present two African descendant patients, father and daughter, with P5'N deficiency, both born from first cousins. Investigation of the promoter polymorphism of the uridine diphospho glucuronosyl transferase 1A (UGT1A) gene revealed that the father was homozygous for the allele (TA7) and the daughter heterozygous (TA6/TA7). P5'NI gene (NT5C3) gene sequencing revealed a further change in homozygosity at amino acid position 56 (p.R56G), located in a highly conserved region. Both patients developed gallstones; however the father, who had undergone surgery for the removal of stones, had extremely severe intrahepatic cholestasis and, liver biopsy revealed fibrosis and siderosis grade III, leading us to believe that the homozygosity of the UGT1A polymorphism was responsible for the more severe clinical features in the father. Moreover, our results show how the clinical expression of hemolytic anemia is influenced by epistatic factors and we describe a new mutation in the P5'N gene associated with enzyme deficiency, iron overload, and severe gallstone formation. To our knowledge, this is the first description of P5'N deficiency in South Americans.