Changes in social inequalities in disability-free life expectancy in Southern Europe: the case of the Basque Country

Background: Health expectancy is a useful tool to monitor health inequalities. The evidence about the recent changes in social inequalities in healthy expectancy is relatively scarce and inconclusive, and most studies have focused on Anglo-Saxon and central or northern European countries. The objective of this study was to analyse the changes in socioeconomic inequalities in disability-free life expectancy in a Southern European population, the Basque Country, during the first decade of the 21st century. Methods: This was an ecological cross-sectional study of temporal trends on the Basque population in 1999-2003 and 2004-2008. All-cause mortality rate, life expectancy, prevalence of disability and disability free-life expectancy were calculated for each period according to the deprivation level of the area of residence. The slope index of inequality and the relative index of inequality were calculated to summarize and compare the inequalities in the two periods. Results: Disability free-life expectancy decreased as area deprivation increased both in men and in women. The difference between the most extreme groups in 2004-2008 was 6.7 years in men and 3.7 in women. Between 1999-2003 and 2004-2008, socioeconomic inequalities in life expectancy decreased, and inequalities in disability-free expectancy increased in men and decreased in women. Conclusions: This study found important socioeconomic inequalities in health expectancy in the Basque Country. These inequalities increased in men and decreased in women in the first decade of the 21st century, during which the Basque Country saw considerable economic growth.

Serie Vídeos tutoriales para fonética (volumen 2). Video 6. Diálogo entre pares que no son conscientes de ser grabados

Esta es una colección de 6 vídeos tutoriales que pueden ser empleados como material educativo en los cursos de fonética en el ámbito universitario. Tratan principalmente del cómo se puede obtener información desde las palabras aisladas, como se observa en las técnicas de los vídeos 1-2, pasando por datos obtenidos con participación del investigador, característica aún presente en los vídeos 3-4, hasta enunciados íntegros sin necesidad del investigador presente, tal como se ilustra en los vídeos 5-6. Se trata de establecer una reflexión entre la necesidad de identificar el grado de espontaneidad a la hora de brindar información por parte del hablante y la posibilidad (o la necesidad) de cuantificar los datos que se obtienen.

Alveolar nitric oxide and its role in pediatric asthma control assessment

Resumen Background: Nitric oxide can be measured at multiple flow rates to determine proximal (maximum airway nitric oxide flux; Jaw(NO)) and distal inflammation (alveolar nitric oxide concentration; CA(NO)). The main aim was to study the association among symptoms, lung function, proximal (maximum airway nitric oxide flux) and distal (alveolar nitric oxide concentration) airway inflammation in asthmatic children treated and not treated with inhaled glucocorticoids. Methods: A cross-sectional study with prospective data collection was carried out in a consecutive sample of girls and boys aged between 6 and 16 years with a medical diagnosis of asthma. Maximum airway nitric oxide flux and alveolar nitric oxide concentration were calculated according to the two-compartment model. In asthmatic patients, the asthma control questionnaire (CAN) was completed and forced spirometry was performed. In controls, differences between the sexes in alveolar nitric oxide concentration and maximum airway nitric oxide flux and their correlation with height were studied. The correlation among the fraction of exhaled NO at 50 ml/s (FENO50), CA(NO), Jaw(NO), forced expiratory volume in 1 second (FEV1) and the CAN questionnaire was measured and the degree of agreement regarding asthma control assessment was studied using Cohen's kappa. Results: We studied 162 children; 49 healthy (group 1), 23 asthmatic participants without treatment (group 2) and 80 asthmatic patients treated with inhaled corticosteroids (group 3). CA(NO) (ppb) was 2.2 (0.1-4.5), 3 (0.2-9.2) and 2.45 (0.1-24), respectively. Jaw(NO) (pl/s) was 516 (98.3-1470), 2356.67 (120-6110) and 1426 (156-11805), respectively. There was a strong association (r = 0.97) between FENO50 and Jaw(NO) and the degree of agreement was very good in group 2 and was good in group 3. There was no agreement or only slight agreement between the measures used to monitor asthma control (FEV1, CAN questionnaire, CA(NO) and Jaw(NO)). Conclusions: The results for CA(NO) and Jaw(NO) in controls were similar to those found in other reports. There was no agreement or only slight agreement among the three measure instruments analyzed to assess asthma control. In our sample, no additional information was provided by CA(NO) and Jaw(NO).

Cytokine pathway disruption in a mouse model of schizophrenia induced by Munc18-1a overexpression in the brain

Background: An accumulating body of evidence points to the significance of neuroinflammation and immunogenetics in schizophrenia, and an imbalance of cytokines in the central nervous system (CNS) has been suggested to be associated with the disorder. Munc18-overexpressing mice (Munc18-OE) have provided a model for the study of the alterations that may underlie the symptoms of subjects with schizophrenia. The aim of the present study was to elucidate the involvement of neuroinflammation and cytokine imbalance in this model. Methods: Cytokines were evaluated in the cortex and the striatum of Munc18-OE and wild-type (WT) mice by enzyme-linked immunosorbent assay (ELISA). Protein levels of specific microglia and macrophage, astrocytic and neuroinflammation markers were quantified by western blot in the cortex and the striatum of Munc18-OE and WT mice. Results: Each cytokine evaluated (Interferon-gamma (IFN-gamma), Tumor Necrosis Factor-alpha (TNF-alpha), Interleukin-2 (IL-2) and CCL2 chemokine) was present at higher levels in the striatum of Munc18-OE mice than WT. Cortical TNF-alpha and IL-2 levels were significantly lower in Munc18-OE mice than WT mice. The microglia and macrophage marker CD11b was lower in the cortexes of Munc18-OE mice than WT, but no differences were observed in the striatum. Glial Fibrillary Acidic Protein (GFAP) and Nuclear Factor-kappaB (NF-kappa B)p65 levels were not different between the groups. Interleukin-1beta (IL-1 beta) and IL-6 levels were beneath detection limits. Conclusions: The disrupted levels of cytokines detected in the brain of Munc18-OE mice was found to be similar to clinical reports and endorses study of this type for analysis of this aspect of the disorder. The lower CD11b expression in the cortex but not in the striatum of the Munc18-OE mice may reflect differences in physiological activity. The cytokine expression pattern observed in Munc18-OE mice is similar to a previously published model of schizophrenia caused by maternal immune activation. Together, these data suggest a possible role for an immune imbalance in this disorder.

Diseño de un programa de Surf recreativo enfocado a colectivos con Síndrome de Down de 6 a 10 años

El objetivo de este trabajo es diseñar un programa de surf recreativo enfocado a colectivos con Síndrome de Down de 6 a 10 años. El Síndrome de Down se define como una discapacidad intelectual causada por una alteración en el par de cromosomas 21 (OMS, 2011). Resulta de especial relevancia el tratamiento de dicha discapacidad de manera no farmacológica, destacando la actividad física, en este caso el surf, como elemento inclusivo a nivel físico, psicológico y social. Se analizan distintos programas de Actividad Física en el medio acuático con personas con Síndrome de Down y se presenta el Surf como elemento que provoca grandes beneficios. A continuación se presenta el diseño de un programa que podría llevarse a cabo en un entorno cercano a nuestro territorio con un atractivo elevado ya que se trata de un proyecto innovador y beneficioso para personas con Síndrome de Down y sus familiares.

Efectos de la actividad física en la evolución de las relaciones interpersonales en alumnado de 5º y 6º de Primaria y 1º y 2º de Secundaria en campamento escolar de Vela

Hoy en día toda o casi toda la población de nuestra sociedad conocemos o bien de primera mano o de segunda mano los campamentos. Seguramente un alto porcentaje de la población haya estado en alguno, y el que no, habrá oído hablar de ellos. En los campamentos, se crea un caldo de cultivo idóneo para la socialización de los niños, ¿pero se les da las mismas oportunidades a todos? Un niño o niña con poca capacidad de socialización no va a tener las mismas oportunidades que los demás, por lo que es necesario buscar una metodología que ayude a la socialización de todos. Así pues, mediante este trabajo se plantea una metodología basada en la actividad física, y dentro de ella en los juegos cooperativos. Se analizará si con la utilización de juegos cooperativos se da un cambio en las relaciones interpersonales de los niños, y de ser así, si el cambio es positivo, es decir, si se trabajan las relaciones desde el aspecto de los valores humanos. Por consiguiente, veremos que los juegos cooperativos sirven y en gran medida para influenciar en ese cambio en las relaciones interpersonales de los niños en un campamento escolar de vela, siendo ese cambio muy positivo y dándose en la mayoría de los niños.

铒玻璃在1．54μm实现1 Hz下3 J和5 Hz下0．6 J的激光输出

近年来,随着激光告警、激光指示、风速测量、激光雷达尤其是激光美容等方面的需求逐渐增加,要求掺铒激光玻璃能够实现比以往更高重复频率以及更大能量的激光输出,其中对脉冲能量的要求达1～10 J。

Desarrollo de una herramienta analítica para resolución del problema directo e inverso de un robot serie de 6 grados de libertad.

[ES]En el presente trabajo de fin de grado se expondrá el análisis cinemático de un robot IRB120 de ABB y el desarrollo de una herramienta grafica para su visualización. Comenzando por un estudio del estado del arte de la robótica industrial. El análisis cinemático es plantear las ecuaciones del robot y la resolución del problema directo e inverso mediante el software Matlab. Por último, la herramienta grafica muestra el movimiento del robot y los sistemas de referencia en la trayectoria introducida por el usuario.

Property studies of optical waveguide formed by 6.0 MeV carbon ion implantation into Nd : silicate glass

Nd:silicate glass was implanted at room temperature by 6.0 MeV C3+ ions with a dose of 2.0 x 10(15) ions cm(-2). A waveguide with thickness of about 6.3 mu m was formed. The prism-coupling method was used to observe the dark modes of the waveguide at 633 nm and 1539 nm, respectively. There are three dark modes at 633 nm, of which one is the enhanced-index mode. The propagation loss of the enhanced-index mode in the waveguide measured at 633 nm is 0.42 dB cm(-1) after annealing at 217 degrees C for 35 min. The reflectivity calculation method was applied to simulate the refractive index profiles in the waveguide. The mode optical near-field output at 633 nm was presented.

"Nortia, te veneror" (CLE 1530 = CIL 6. 537): la defensa de Avieno de la fortuna y del encomio propio

Este trabajo ha sido realizado dentro del Grupo de Investigación GIU 10-19 “LITTERARVM. Grupo de Investigación en Literatura, Retórica y Tradición Clásica” de la UPV/EHU.

Statistiques de peches des Chalutiers Ivoiriens, Annee 1983. Campagnes Chalutage Togo 5 & 6

This publication gives fishery statistics relating to the landings of the Ivorian trawlers in Abidjan in 1983. The data used are the inquiries made by the C.R.O. on the boats and the auction sheets of the fishing harbour. The data processing was executed on the C.R.O. computer.

Infrared (1.2-1.6 mu m) luminescence in Yb, Cr : YAG with 940 nm diode pumping

Infrared (1.2-1.6 mum) luminescence in a yttrium aluminium garnet (YAG) crystal, co-doped with Yb (10 at.%) and Cr (0.05 at.%) ions, was investigated under CW laser diode pumping (lambda = 940 nm). The Cr4+ emission band was observed with its peak at 1.35 mum and measured to be about 6% with respect to Yb3+ IR luminescence (lambda = 1.03 mum). Analysis of the crystal absorption and luminescence spectra allows one to conclude that Yb3+-Cr4+ energy transfer is a mechanism responsible for the B-3(2)(T-3(2))-B-3(1)((3)A(2)) emission of Cr4+ ions. This crystal is promising as an efficient source of the near infrared emission. (C) 2004 Elsevier B.V. All rights reserved.