Fünf Wochen in Brody unter jüdisch-russischen Emigranten : ein Beitr. zur Gesch. d. russ. Judenverfolgung

von M. Friedländer

Der Talmudjude von Rohling in der Schwurgerichtsverhandlung vom 28. Oktober 1882 : zur Abwehr und Verständigung

von D. Löwy

Autobiographie S. D. Luzzato's, Biographie Ezechia Luzzato's u. Luigi Pasquali's

aus dem Italienischen ins Deutsche übertr. von M. Grünwald, u. mit Anm. vers. von J. Luzzato, S. Morais

Blüthen von den Gefilden Juda's : Traduktionen u. Versionen auf d. Gebiete d. jüdischen Schriftthums

ges. von Leopold Freund

D��vār be-ʿittô : ein worṭ tzur tzaiṭ ; gewidmeṭ le-... Moše Frei

... Meir Ben- ... Jonha Reichharṭ

A 3-D CT assisted Monte Carlo evaluation of intracavitary brachytherapy implants

Intracavitary brachytherapy (ICB) combined with external beam irradiation for treatment of cervical cancer is highly successful in achieving local control. The M.D. Anderson Cancer Center employs Fletcher Suit Delclos (FSD) applicators. FSD applicators contain shields to limit dose to critical structures. Dosimetric evaluation of ICB implants is limited to assessing dose at reference points. These points serve as surrogates for treatment intensity and critical structure dose. Several studies have mentioned that the ICRU38 reference points inadequately characterize the dose distribution. Also, the ovoid shields are rarely considered in dosimetry. ^ The goal of this dissertation was to ascertain the influence of the ovoid shields on patient dose distributions. Monte Carlo dosimetry (MCD) was applied to patient computed tomography(CT) scans. These data were analyzed to determine the effect of the shields on dose to standard reference points and the bladder and rectum. The hypothesis of this work is that the ICRU38 bladder and rectal points computed conventionally are not clinically acceptable surrogates for the maximum dose points as determined by MCD. ^ MCD was applied to the tandem and ovoids. The FSD ovoids and tandem were modeled in a single input file that allowed dose to be calculated for any patient. Dose difference surface histograms(DDSH) were computed for the bladder and rectum. Reference point doses were compared between shielded and unshielded ovoids, and a commercial treatment planning system. ^ The results of this work showed the tandem tip screw caused a 33% reduction in dose. The ovoid shields reduced the dose by a maximum of 48.9%. DDSHs revealed on average 5% of the bladder surface area was spared 53 cGy and 5% of the rectal surface area was spared 195 cGy. The ovoid shields on average reduced the dose by 18% for the bladder point and 25% for the rectal point. The Student's t-test revealed the ICRU38 bladder and rectal points do not predict the maximum dose for these organs. ^ It is concluded that modeling the tandem and ovoid internal structures is necessary for accurate dose calculations, the bladder shielding segments may not be necessary, and that the ICRU38 bladder point is irrelevant. ^

ACCURACY OF THE BRCAPRO RISK ASSESSMENT MODEL IN MALES PRESENTING TO MD ANDERSON FOR BRCA TESTING

ACCURACY OF THE BRCAPRO RISK ASSESSMENT MODEL IN MALES PRESENTING TO MD ANDERSON FOR BRCA TESTING Publication No. _______ Carolyn A. Garby, B.S. Supervisory Professor: Banu Arun, M.D. Hereditary Breast and Ovarian Cancer (HBOC) syndrome is due to mutations in BRCA1 and BRCA2 genes. Women with HBOC have high risks to develop breast and ovarian cancers. Males with HBOC are commonly overlooked because male breast cancer is rare and other male cancer risks such as prostate and pancreatic cancers are relatively low. BRCA genetic testing is indicated for men as it is currently estimated that 4-40% of male breast cancers result from a BRCA1 or BRCA2 mutation (Ottini, 2010) and management recommendations can be made based on genetic test results. Risk assessment models are available to provide the individualized likelihood to have a BRCA mutation. Only one study has been conducted to date to evaluate the accuracy of BRCAPro in males and was based on a cohort of Italian males and utilized an older version of BRCAPro. The objective of this study is to determine if BRCAPro5.1 is a valid risk assessment model for males who present to MD Anderson Cancer Center for BRCA genetic testing. BRCAPro has been previously validated for determining the probability of carrying a BRCA mutation, however has not been further examined particularly in males. The total cohort consisted of 152 males who had undergone BRCA genetic testing. The cohort was stratified by indication for genetic counseling. Indications included having a known familial BRCA mutation, having a personal diagnosis of a BRCA-related cancer, or having a family history suggestive of HBOC. Overall there were 22 (14.47%) BRCA1+ males and 25 (16.45%) BRCA2+ males. Receiver operating characteristic curves were constructed for the cohort overall, for each particular indication, as well as for each cancer subtype. Our findings revealed that the BRCAPro5.1 model had perfect discriminating ability at a threshold of 56.2 for males with breast cancer, however only 2 (4.35%) of 46 were found to have BRCA2 mutations. These results are significantly lower than the high approximation (40%) reported in previous literature. BRCAPro does perform well in certain situations for men. Future investigation of male breast cancer and men at risk for BRCA mutations is necessary to provide a more accurate risk assessment.

(Reseña sobre) Vicente Blasco Ibáñez: An Annotated Bibliography 1975-2002, de Christopher L. Anderson y Paul C. Smith

Fil: Contreras, María de los Angeles. Universidad Nacional de La Plata. Facultad de Humanidades y Ciencias de la Educación; Argentina.

La Plata y la ideología del progreso : redes y espacios culturales en la reprodución de un habitus laicista, 1882-1916

Fil: Vallejo, Gustavo Gabriel. Universidad Nacional de La Plata. Facultad de Humanidades y Ciencias de la Educación; Argentina.

Francisco Berra y la educación positivista en el Uruguay (1874-1882)

Las ideas de Berra sobre la enseñanza, que tend��an a hacer imperar en la educación una rígida metodología naturalista, ejercieron su influencia sobre la educación argentina, aún antes de su actuación en el gobierno escolar de la provincia de Buenos Aires. A través de su archivo documental puede conocerse la vida intelectual rioplatense -en ambas orillas-, así como el mundo estrictamente escolar y sus manifestaciones pedagógicas correspondientes. En este trabajo, nos proponemos estudiar su actuación en el Uruguay entre los años 1874 a 1882, cuya elección no es casual. Este período comprende el inicio de su actividad pedagógica en Uruguay, la elaboración de su obra principal ("Los apuntes de pedagogía") y su participación en el Congreso pedagógico de Buenos Aires, en pleno embate entre liberales y clericales y las polémicas desatadas por el avance del positivismo.

Juana Manuela Gorriti. Cincuenta y tres cartas inéditas a Ricardo Palma. Fragmentos de lo íntimo. Buenos Aires-Lima 1882-1891, de Graciela Batticuore

Fil: Sancholuz, Carolina. Universidad Nacional de La Plata. Facultad de Humanidades y Ciencias de la Educación; Argentina.

(Reseña sobre) Vicente Blasco Ibáñez: An Annotated Bibliography 1975-2002, de Christopher L. Anderson y Paul C. Smith

Fil: Contreras, María de los Angeles. Universidad Nacional de La Plata. Facultad de Humanidades y Ciencias de la Educación; Argentina.

La Plata y la ideología del progreso : redes y espacios culturales en la reprodución de un habitus laicista, 1882-1916

Fil: Vallejo, Gustavo Gabriel. Universidad Nacional de La Plata. Facultad de Humanidades y Ciencias de la Educación; Argentina.

Francisco Berra y la educación positivista en el Uruguay (1874-1882)

Las ideas de Berra sobre la enseñanza, que tend��an a hacer imperar en la educación una rígida metodología naturalista, ejercieron su influencia sobre la educación argentina, aún antes de su actuación en el gobierno escolar de la provincia de Buenos Aires. A través de su archivo documental puede conocerse la vida intelectual rioplatense -en ambas orillas-, así como el mundo estrictamente escolar y sus manifestaciones pedagógicas correspondientes. En este trabajo, nos proponemos estudiar su actuación en el Uruguay entre los años 1874 a 1882, cuya elección no es casual. Este período comprende el inicio de su actividad pedagógica en Uruguay, la elaboración de su obra principal ("Los apuntes de pedagogía") y su participación en el Congreso pedagógico de Buenos Aires, en pleno embate entre liberales y clericales y las polémicas desatadas por el avance del positivismo.