The effect of 17-B estradiol therapy on bone mineral density and structure of alveolar bone in the ovariectomized rat model of postmenopausal osteoporosis

The ovariectomized (OVX) rat, a preclinical model for studying postmenopausal bone loss, may also be used to study differences in alveolar bone (AB). The objectives of this study were to quantify the differences in AB following estrogen replacement therapy (ERT), and to investigate the relationship between AB structure and density, and trabecular bone at the femoral neck (FN) and third lumbar vertebral body (LB3). Estrogen treated rats had a higher bone volume fraction (BV/TV) at the AB region (9.8% P < 0.0001), FN (12% P < 0.0001), and LB3 (11.5% P < 0.0001) compared to the OVX group. BV/TV of the AB was positively correlated with the BV/TV at the FN (r = 0.69 P < 0.0001) and the LB3 (r = 0.75 P < 0.0001). The trabecular number (Tb.N), trabecular separation (Tb.Sp), and structure model index (SMI) were also positively correlated (P < 0.05) between the AB and FN (r = 0.42, 0.49, and 0.73, respectfully) and between the AB and LB3 (r = 0.44, 0.63, and 0.69, respectfully). Given the capacity of AB to respond to ERT, future preclinical drug/nutritional intervention studies aimed at improving skeletal health should include the AB as a region of interest (ROI).

Presentation from the Office of Macdonald and Rykert regarding the Case of O'Connor vs. the Great Western Railway Co.

Presentation from the Office of Macdonald and Rykert regarding the Case of O’Connor vs. the Great Western Railway Co. This is a handwritten, 9 ½ page double sided document). Some of the witnesses for the plaintiff included: Robert Johnson, John Ryder, Edward Duffy, Gilbert Gregory, John Cutter, James Patterson, Samuel Rush and Francis Bigger, among others. They claimed that the Great Western Railway Co. was destroying their land. Jacob Dittrick claimed that the culverts were not large enough to carry off water. Mr. Jackson noticed injury to his flats. Wild grass was destroying the bottom grass, May 6, 1836.

Approximate estimate of the cost of extending the Port Dalhousie and Thorold Railway from Geneva Street to the Great Western Railway Station at Lock no. 12

Approximate estimate of the cost of extending the Port Dalhousie and Thorold Railway from Geneva Street to the Great Western Railway Station at Lock no. 12 (2 copies) [one appears to be a rough copy] (2 pages, handwritten), Feb. 2, 1855.

Mr. Woodward’s timetable regarding the suspension bridge to Toronto via the Great Western Railway and Port Dalhousie Railway

Mr. Woodward’s timetable regarding the suspension bridge to Toronto via the Great Western Railway and Port Dalhousie Railway (1 page, handwritten), Jan. 22, 1856

Iron Mountain Route Railway schedule: the great through line St. Louis, Arkansas and Texas to the Hot Springs of Arkansas

Iron Mountain Route Railway schedule: the great through line St. Louis, Arkansas and Texas to the Hot Springs of Arkansas.

Letter and envelope addressed to S.D. Woodruff from the office of T.B. Stewart and Co. of New York

Letter and envelope addressed to S.D. Woodruff from the office of T.B. Stewart and Co. of New York, Manufacturers of Mantles, Marble and Wood Mantels. The letter states that the heater and grates have been shipped, July 14, 1876.

Post card with a notice of freight arrival addressed to S.D. Woodruff from the Great Western Railway for castings, a keg and grates

Post card with a notice of freight arrival addressed to S.D. Woodruff from the Great Western Railway for castings, a keg and grates, Aug.11, [1876].

Indenture of agreement between the Great Western Railway Company and the Erie and Ontario Railway Company

Indenture of agreement between the Great Western Railway Company and the Erie and Ontario Railway Company in order for the companies to unite, March 20, 1854.

Frederick the great and his court

UANL

Frederick the great and his family : an historical novel

UANL

New York and it's institutions, 1609-1871, a library of information, pertaining to the great Metropolis..

UANL

Explaining the Great Divergence: Medium and Message on the Eurasian Land Mass, 1700-1850

Between 1700 and 1850, per-capita income doubled in Europe while falling in the rest of Eurasia. Neither geography nor economic institutions can explain this sudden divergence. Here the consequences of differences in communications technology are examined. For the first time, there appeared in Europe a combination of a standardized medium (national vernaculars with a phonetic alphabet) and a non-standardized message (competing religious, political and scientific ideas). The result was an unprecedented fall in the cost of combining ideas and burst of productivity-raising innovation. Elsewhere, decreasing standardization of the medium and increasing standardization of the message blocked innovation.

Village sermons on the chief articles of faith, &c., on the christian character, and on some of the relative duties...

UANL