Operator's, organizational, and direct support maintenance manual [microform] : kitchen, field, trailer mounted MKT-75-NSN : (7360-00-138-7782), MKT-75A-NSN : (7360-01-155-6020), MKT-82-NSN : (7360-01-155-6020).

"1 June 1984."

Connecting and switching kit MX-155/GT.

"8 September 1944."

Operator's, organizational, direct support, and general support maintenance repair parts and special tools lists (including depot maintenance repair parts and sepcial [sic] tools) : masts AB-155/U (FSN 5820-251-2366), AB-155A/U (FSN 5985-507-6261), and AB-155B/U (FSN 5985-732-5146).RC-74 and CY-6314A/PRC-74 (NSN 5820-00-156-3934).

Includes index.

Organizational, direct support, and general support maintenance repair parts and special tools lists (including depot maintenance repair parts and special tools) : coder-control, interrogation sets KY-97/TPX, KY-97A/TPX (FSN 5895-378-4782), KY-97B ....

"8 March 1974."

Operator's and organizational maintenance manual : data processing set, AN/UYK-64(V)1 (NSN 7035-01-155-0153), AN/UYK-64(V)1x (NSN 7035-01-155-0154), AN/UYK-64(V)2 (NSN 7035-01-166-7855), AN/UYK-64(V)2x (NSN 7035-01-155-0155), AN/UYK-64(V)3 (NSN 7035-01-155-0156), AN/UYK-64(V)3x (NSN 7035-01-155-0157) ...

Includes index.

Operator's and organizational maintenance manual : disk memory unit MU-768/G, (NSN 7025-01-155-0172).

Includes index.

Organizational and direct support maintenance repair parts and special tools list (including depot maintenance repair parts and special tools) for maintenance shop facility, mobile V-452/MYK-8(V), (NSN 4940-00-155-8519) and storage facility, mobile V-483-MYK-8(V), (NSN 4940-00-596-4197).

Includes index.

Flood control : hearing before the Committee on Rules, House of Representatives, Seventieth Congress, first session on H. Res. 155, for the con sideration of S. 3740, a bill for the control of floods on the Mississippi River from the Head of Passes to Cape Girardeau, Mo., and for other purposes.

Mode of access: Internet.

Quartets for stringed instruments: K.80, 155, 156, 157, 158, 159, 160, 168, 170, 171, 172, 173.

G major, K.80.--D major, K.155.--G major, K.156.--C major, K.157.--F major, K.158.--B♭ major, K.159.--E♭ major, K.160.--F major, K.168.--A major, K.169.--C major, K.170.--E♭ major, K.171.--B♭ major, K.172.--D minor, K.173.

MicroRNA-155 promotes resolution of hypoxia-inducible factor 1α activity during prolonged hypoxia

The hypoxia-inducible factor (HIF) is a key regulator of the transcriptional response to hypoxia. While the mechanism underpinning HIF activation is well understood, little is known about its resolution. Both the protein and the mRNA levels of HIF-1a (but not HIF-2a) were decreased in intestinal epithelial cells exposed to prolonged hypoxia. Coincident with this, microRNA (miRNA) array analysis revealed multiple hypoxiainducible miRNAs. Among these was miRNA-155 (miR-155), which is predicted to target HIF-1a mRNA. We confirmed the hypoxic upregulation of miR-155 in cultured cells and intestinal tissue from mice exposed to hypoxia. Furthermore, a role for HIF-1a in the induction of miR-155 in hypoxia was suggested by the identification of hypoxia response elements in the miR-155 promoter and confirmed experimentally. Application of miR-155 decreased the HIF-1a mRNA, protein, and transcriptional activity in hypoxia, and neutralization of endogenous miR-155 reversed the resolution of HIF-1a stabilization and activity. Based on these data and a mathematical model of HIF-1a suppression by miR-155, we propose that miR-155 induction contributes to an isoform-specific negative-feedback loop for the resolution of HIF-1a activity in cells exposed to prolonged hypoxia, leading to oscillatory behavior of HIF-1a-dependent transcription. © 2011, American Society for Microbiology.

Cocaine Enhances HIV-1 Infectivity in Monocyte Derived Dendritic Cells by Suppressing microRNA-155

Cocaine and other drugs of abuse increase HIV-induced immunopathogenesis; and neurobiological mechanisms of cocaine addiction implicate a key role for microRNAs (miRNAs), single-stranded non-coding RNAs that regulate gene expression and defend against viruses. In fact, HIV defends against miRNAs by actively suppressing the expression of polycistronic miRNA cluster miRNA-17/92, which encodes miRNAs including miR-20a. IFN-g production by natural killer cells is regulated by miR-155 and this miRNA is also critical to dendritic cell (DC) maturation. However, the impact of cocaine on miR-155 expression and subsequent HIV replication is unknown. We examined the impact of cocaine on two miRNAs, miR-20a and miR-155, which are integral to HIV replication, and immune activation. Using miRNA isolation and analysis, RNA interference, quantitative real time PCR, and reporter assays we explored the effects of cocaine on miR-155 and miR-20 in the context of HIV infection. Here we demonstrate using monocyte-derived dendritic cells (MDCCs) that cocaine significantly inhibited miR-155 and miR-20a expression in a dose dependent manner. Cocaine and HIV synergized to lower miR-155 and miR-20a in MDDCs by 90%. Cocaine treatment elevated LTR-mediated transcription and PU.1 levels in MDCCs. But in context of HIV infection, PU.1 was reduced in MDDCs regardless of cocaine presence. Cocaine increased DC-SIGN and and decreased CD83 expression in MDDC, respectively. Overall, we show that cocaine inhibited miR-155 and prevented maturation of MDDCs; potentially, resulting in increased susceptibility to HIV-1. Our findings could lead to the development of novel miRNA-based therapeutic strategies targeting HIV infected cocaine abusers.

Global compilation of benthic data sets I

Approaches to quantify the organic carbon accumulation on a global scale generally do not consider the small-scale variability of sedimentary and oceanographic boundary conditions along continental margins. In this study, we present a new approach to regionalize the total organic carbon (TOC) content in surface sediments (<5 cm sediment depth). It is based on a compilation of more than 5500 single measurements from various sources. Global TOC distribution was determined by the application of a combined qualitative and quantitative-geostatistical method. Overall, 33 benthic TOC-based provinces were defined and used to process the global distribution pattern of the TOC content in surface sediments in a 1°x1° grid resolution. Regional dependencies of data points within each single province are expressed by modeled semi-variograms. Measured and estimated TOC values show good correlation, emphasizing the reasonable applicability of the method. The accumulation of organic carbon in marine surface sediments is a key parameter in the control of mineralization processes and the material exchange between the sediment and the ocean water. Our approach will help to improve global budgets of nutrient and carbon cycles.