Fighting undernutrition: don't forget the bugs

Severe acute malnutrition is a major cause of child death in developing countries. In a recent study, Smith et al.(2013) monitored a large twin cohort in Malawi to unveil a causal relationship between gut microbiota and weight loss in undernutrition .

Revisiting the 'modern' multinational enterprise theory: an emerging-market multinational perspective

Using Triad-based multinational enterprises as their empirical setting, influential scholars in international management uncovered key organizational characteristics needed to create globally integrated and locally responsive multinationals. They proposed a “modern” theory of multinationals' organization (Hedlund, 1994). But recently, a new generation of multinationals from emerging markets has appeared. Little is known about their organizational choices and some scholars even doubt that they leverage organizational capabilities altogether. Does the “modern” theory still hold in their case? This exploratory study of three emerging-market multinationals (EMNEs) discloses that for reasons related to their origin in emerging economies and to the competitive specificities of these economies, EMNEs approach the global and local conundrum in ways which are both similar – and vastly different – from recommendations of the “modern” theory. We inductively develop a new theory that accounts for the evolution of organizational capabilities in EMNEs to reconcile global integration and local responsiveness. We discuss its implications for the executives of both emerging and Triad-based multinationals.

Gestão da inovação no setor público: acumulação de capacidades tecnológicas e os processos subjacentes de aprendizagem: evidências da Secretaria do Tesouro Nacional do Brasil durante o período de 1986 a 2005

Estudo de caso, referente a acumulação de capacidades tecnológicas e aos processos subjacentes de aprendizagem no âmbito da Secretaria do Tesouro Nacional do Brasil - entre 1986 a 2005

Competitividade no agronegócio: proposta de modelo para elaboração de estratégia de integração de cadeias para os defensivos agrícolas – o caso do café

A produção sustentável de alimentos é fundamental para suportar o crescimento populacional. Segundo estimativa da FAO, se a população atingir 9,1 bilhões de habitantes em 2050, a produção de alimentos deverá crescer 70%, e a produção nos países em desenvolvimento deverá dobrar. Ou seja, a maior parte do crescimento vem de países emergentes, onde se concentra o maior potencial de crescimento agrícola. Com o aumento populacional e o aumento da renda da população destes países emergentes, há aumento na demanda por produtos de melhor qualidade, fazendo com que o crescimento na produção de alimentos seja não somente de quantidade, mas também, de qualidade e valor. Portanto, a maior a exigência em termos de segurança do alimento, faz com que rastreabilidade e transparência com relação ao uso de tecnologias de produção se transformem em fatores que influenciam a aceitação de alimentos por parte dos consumidores do mercado doméstico e também de mercados internacionais. Neste contexto, o varejo ganha importância estratégica pela proximidade do seu negócio com o consumidor final. Ele é o primeiro elo da cadeia a receber informações sobre o cliente em termos de comportamento de compra e demandas, podendo assim, repassá-las aos outros elos da cadeia chegando até os produtores, que tem que ajustar suas práticas em geral, e principalmente, as práticas agronômicas, no que diz respeito à qualidade e a segurança do alimento. As empresas de insumos e as agroindústrias, que contribuem para uma produção agrícola sustentável terão a preferência dos produtores rurais e varejistas, que tem a missão de entregar produtos de qualidade, seguros, de forma conveniente para o consumidor final que é o elo capaz de movimentar a cadeia em uma única direção - a da agricultura sustentável. É neste contexto que as empresas de defensivos agrícolas devem desenvolver suas estratégias de negócio. Torna-se necessário ter maior “controle” sobre a cadeia, visando o uso correto de seus produtos, visando contribuir para a agricultura sustentável, ganhando participação de mercado e/ou aumentando sua rentabilidade. Para isso, algumas empresas têm desenvolvido estratégias de coordenação de cadeias, ou “food value chain”, com alguns casos exitosos. Neste trabalho, é proposta metodologia para o desenvolvimento e implementação de estratégias de “food value chain” para os defensivos agrícolas. Ao final do trabalho, conclui-se que existem ganhos importantes para a empresa que adota este tipo de estratégia; entretanto, há um aumento na complexidade da operação. Por isso, é uma escolha importante, que deve ser parte da missão da empresa.

Estratégias de desenvolvimento do turismo: em busca de uma tipologia

BEZERRA, Márcia Maria de Oliveira. Estrategias de desenvolvimento do turismo: em busca de uma tipologia. Economia e Sociedade, Campinas, v. 15, n. 2, p. 347-374, ago. 2006.

Comparação da eficácia clínica da associação amoxicilina e ácido clavulânico com oxacilina e ceftriaxone para tratamento hospitalar de pneumonia comunitária grave em crianças: estudo clínico randomizado

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

O programa Saúde da Família e a promoção do envelhecimento saudável

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Análise celular e molecular da ação do peptídeo Ac2-26 da proteína anti-inflamatória Anexina A nas células de carcinoma de colo de útero

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Greening a Brazilian cotton seed processing company: from challenges to strategic opportunities

This paper aims to shed light on a current and important theme that has been gaining increasing importance for governments, society and companies: the greening of agricultural companies in developing countries. The research objective is to classify a Brazilian cotton seed processing company in the evolutionary stages of environmental management: reactive, preventive or proactive. Design/methodology/approach– A case study was conducted in a Brazilian cotton seed processing company.Findings– The main results are: the studied company is positioned in the preventive stage of environmental management; this company is investing in operational green practices; environmental management in this company is motivated by various factors aiming at an increased competitive advantage. Finally, it can be concluded that this company is looking for green opportunities towards the proactive environmental management stage.

Acute promyelocytic leukemia associated with the PLZF-RARA fusion gene: two additional cases with clinical and laboratorial peculiar presentations

Acute promyelocytic leukemia (APL) is characterized by the presence of the t(15;17) and PML-RARa rearrangement, with good response to treatment with retinoids. However, few cases of variant APL involving alternative chromosomal aberrations have been reported, including t(11;17)(q23;q21) (Wells et al. in Nat Genet 17:109-113, 1; Arnould et al. in Hum Mol Genet 8:1741-1749, 2) t(5;17)(q35;q12-21), t(11;17)(q13;q21) (Grimwade et al in Blood 96:1297-1308, 3) and der(17) (Rego et al. in Blood (ASH Annual Meeting Abstracts)114:Abstract 6, 4), whereby RARa is fused to the PLZF, NPM, NuMA, and STAT5b genes, respectively, have been described. These cases are characterized by distinct morphology, clinical presentation, and in respect to PLZF, a lack of differentiation response to retinoids leading to the need of different approaches concerning diagnostic methods and therapeutics. This paper describes two cases of APL associated with the PLZF-RARA fusion gene enrolled in the IC-APL trial that is a non-randomized, multicenter study conducted in Brazil, Mexico, Chile and Uruguay with the aim to improve the treatment outcome of APL patients in developing countries. These cases, although rare, offer a challenge to its early recognition and proper conduction.

Climate change and the tourism sector: the clean development mechanism, a market instrument under the Kyoto Protocol to achieve multiple objectives

The main objective of this research is to demonstrate that the Clean Development Mechanism (CDM), an instrument created under a global international treaty, can achieve multiple objectives beyond those for which it has been established. As such, while being already a powerful tool to contribute to the global fight against climate change, the CDM can also be successful if applied to different sectors not contemplated before. In particular, this research aimed at demonstrating that a wider utilization of the CDM in the tourism sector can represent an innovative way to foster sustainable tourism and generate additional benefits. The CDM was created by Article 12 of the Kyoto Protocol of the United Nations Framework Convention on Climate Change (UNFCCC) and represents an innovative tool to reduce greenhouse gases emissions through the implementation of mitigation activities in developing countries which generate certified emission reductions (CERs), each of them equivalent to one ton of CO2 not emitted in the atmosphere. These credits can be used for compliance reasons by industrialized countries in achieving their reduction targets. The logic path of this research begins with an analysis of the scientific evidences of climate change and its impacts on different economic sectors including tourism and it continues with a focus on the linkages between climate and the tourism sector. Then, it analyses the international responses to the issue of climate change and the peculiar activities in the international arena addressing climate change and the tourism sector. The concluding part of the work presents the objectives and achievements of the CDM and its links to the tourism sector by considering case studies of existing projects which demonstrate that the underlying question can be positively answered. New opportunities for the tourism sector are available.

Swiss Policies for more Food Security

Resource-poor yet blissful Switzerland is also one of the most food-secure countries in the world: there are abundant food supplies, relatively low retail prices in terms of purchasing power parity, with few poverty traps. Domestic production covers 70% of net domestic consumption. A vast and efficient food reserve scheme insures against import disruptions. Nonetheless, the food security contribution by the four sectoral policies involved is mutually constrained: our agriculture is protected by the world’s highest tariffs. Huge subsidies, surface payments, and some production quotas substitute market signals with rent maximisation. Moreover, these inefficiencies also prevent trade and investment policies which would keep markets open, development policies which would provide African farmers with the tools to become more competitive, and supply policies which would work against speculators. The paralysing effect of Swiss agricultural policies is exacerbated by new “food security subsidies” in the name of “food sovereignty” while two pending people’s initiatives might yet increase the splendid isolation which in effect reduce Swiss farmer competitiveness and global food security. Is there a solution? Absent a successful conclusion of the Doha Round (WTO) or a Transatlantic Trade and Investment Partnership Agreement (TTIP) further market openings and a consequent “recoupling” of taxpayer support to public goods production remain highly un-likely. To the very minimum Switzerland should resume the agricultural reform process, join other countries trying to prevent predatory behaviour of its investors in developing countries, and regionalise its food reserve.

Export platform FDI and firm heterogeneity

This paper investigates theoretically and empirically firms' productivity ranking among traditional horizontal foreign direct investment (HFDI), pure platform FDI (PFDI), and complex platform FDI (CFDI). Using data on Japanese outward FDI, we define firms conducting HFDI or PFDI as those Japanese firms that maintain production affiliates only in the U.S. or Mexico, respectively. The firms for CFDI are defined as having production affiliates in both the U.S. and Mexico. The theoretical illustration shows that the CFDI firms should have the highest productivity when trade costs between the U.S. and Mexico are low. By carefully disentangling firms' self-selection effects from learning-by-investing effects, we find some evidence consistent with this hypothesis for a period of relatively low trade costs. Our results indicate the importance of trade costs in developing countries with neighboring markets in attracting foreign investment by highly productive multinational firms.