974 resultados para Sólido
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Pós-graduação em Química - IQ
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Pós-graduação em Microbiologia - IBILCE
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Pós-graduação em Engenharia Mecânica - FEG
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Pós-graduação em Ciência dos Materiais - FEIS
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Pós-graduação em Engenharia Elétrica - FEIS
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Pós-graduação em Nanotecnologia Farmacêutica - FCFAR
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Human salivary gland tumors originated from intercalated ducts present a broad range of histologic and cytologic patterns, mainly due to the presence of myoepithelial cells. The aim of this study is to verify the differentiation grade of neoplastic cells and a possible relation between myoepithelial cell differentiation and the presence of luminal secretory contents. The expression of vimentin and cytokeratin (CK) intermediate filaments, actin myofilament and epithelial membrane antigen (EMA) was investigated by double labeling immunocytochemical technique, in thirty salivary gland neoplasms: 5 pleomorphic adenomas, 5 myoepitheliomas, 3 basal cell adenomas, 7 adenoid cystic carcinomas (ACC) and 10 polimorphous low grade adenocarcinomas (PLGA). Tumors with intercalated duct differentiation (pleomorphic adenomas, basal cell adenomas and ACC) express CKs 7, 8, 18 and 19 in the luminal cells and coexpress eventually CK14 with these CKs. Some luminal cells stained with anti-EMA antibody, mainly where a secretory content in the lumen was observed. Outer ductal cells and other myoepithelial-like cells express vimentin, sometimes coexpressing actin and/or CK14 with vimentin. Plasmacytoid cells in myoepitheliomas and pleomorphic adenomas express vimentin and rarely CKs 7, 8, 18 and 19, sometimes coexpressing these CKs with CK14 but they are negative for the remaining antigens. Tumors without intercalated duct differentiation (solid basal cell adenoma and PLGA) express vimentin and CKs 7, 8, 14 and 18, sometimes coexpressing CKs 8 and 18 with CK14. In conclusion, in tumors with intercalated duct differentiation, myoepithelial cells express vimentin and sometimes coexpress actin and/or CK14 with vimentin, never coexpressing other CKs with vimentin. CK14 and actin are independently expressed by myoepithelial cells, so their expression is probably induced by different stimulus. However, the secretory function of luminal cells, visualized by EMA staining, ....
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Pós-graduação em Ciência e Tecnologia de Materiais - FC
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Pós-graduação em Química - IQ
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Pós-graduação em Biotecnologia - IQ
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Among numerous studies about the selective collection of solid waste and cooperatives of recyclable materials, this research aims to contribute with the study of these problems from the geographic space. As the world population increases, the issue of solid waste becomes increasingly worrying, due to new consumption patterns that create larger amounts of waste, especially in the urban centers. The recycling appears to be the best solution for this problem since most materials that are currently sent to landfills would become raw material for new products. The Triage Centers performs an important role in this process because they are responsible for sorting, packing and selling the materials arising from the selective collect, so it is necessary to analyze the places where these steps are performed. This study intend to examine the location and distribution of these enterprises in the city of São Paulo in order to provide support for the mitigation of impacts, both environmental and social, from their location, as well as provide support for the expansion of selective collection program in the city. The choice for studying this area was due to the curiosity of investigating the inefficiency of the recycling program in the city of São Paulo, which currently recycles about 1% of all household solid waste collected. Therefore, from a historical survey of the city's recycling programs, technical visits, interviews with responsible agencies and also analysis of the Triage Center's frameworks based on the guidelines from the municipal legislation, it will be evaluated the problems faced by the program for its expansion