Lattice pulling effect and strain relaxation in axial (In, Ga)N/GaN nanowire heterostructures grown on GaN-buffered Si(111) substrate

Transmission electron microscopy and spatially resolved electron energy-loss spectroscopy have been applied to investigate the indium distribution and the interface morphology in axial (In,Ga)N/GaN nanowire heterostructures. The ordered axial (In,Ga)N/GaN nanowire heterostructures with an indium concentration up to 80% are grown by molecular beam epitaxy on GaN-buffered Si(111) substrates. We observed a pronounced lattice pulling effect in all the nanowire samples given in a broad transition region at the interface. The lattice pulling effect becomes smaller and the (In,Ga)N/GaN interface width is reduced as the indium concentration is increased in the (In,Ga)N section. The result can be interpreted in terms of the increased plastic strain relaxation via the generation of the misfit dislocations at the interface.

Genome-Wiide estimates of coancestry, in breeding and effective population size in the Spanish Holstein population

Estimates of effective population size in the Holstein cattle breed have usually been low despite the large number of animals that constitute this breed. Effective population size is inversely related to the rates at which coancestry and inbreeding increase and these rates have been high as a consequence of intense and accurate selection. Traditionally, coancestry and inbreeding coefficients have been calculated from pedigree data. However, the development of genome-wide single nucleotide polymorphisms has increased the interest of calculating these coefficients from molecular data in order to improve their accuracy. In this study, genomic estimates of coancestry, inbreeding and effective population size were obtained in the Spanish Holstein population and then compared with pedigree-based estimates. A total of 11,135 animals genotyped with the Illumina BovineSNP50 BeadChip were available for the study. After applying filtering criteria, the final genomic dataset included 36,693 autosomal SNPs and 10,569 animals. Pedigree data from those genotyped animals included 31,203 animals. These individuals represented only the last five generations in order to homogenise the amount of pedigree information across animals. Genomic estimates of coancestry and inbreeding were obtained from identity by descent segments (coancestry) or runs of homozygosity (inbreeding). The results indicate that the percentage of variance of pedigree-based coancestry estimates explained by genomic coancestry estimates was higher than that for inbreeding. Estimates of effective population size obtained from genome-wide and pedigree information were consistent and ranged from about 66 to 79. These low values emphasize the need of controlling the rate of increase of coancestry and inbreeding in Holstein selection programmes.

Past, present and future of epigenetics applied to livestock breeding

This article reviews the concept of Lamarckian inheritance and the use of the term epigenetics in the field of animal genetics. Epigenetics was first coined by Conrad Hal Waddington (1905–1975), who derived the term from the Aristotelian word epigenesis. There exists some controversy around the word epigenetics and its broad definition. It includes any modification of the expression of genes due to factors other than mutation in the DNA sequence. This involves DNA methylation, post-translational modification of histones, but also linked to regulation of gene expression by non-coding RNAs, genome instabilities or any other force that could modify a phenotype. There is little evidence of the existence of transgenerational epigenetic inheritance in mammals, which may commonly be confounded with environmental forces acting simultaneously on an individual, her developing fetus and the germ cell lines of the latter, although it could have an important role in the cellular energetic status of cells. Finally, we review some of the scarce literature on the use of epigenetics in animal breeding programs.

Synthesis and characterization of low-cost materials for aqueous Na-ion batteries

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Asociación entre factores socioeconómicos y hábitos de limpieza en gestantes de Usaquén y Kennedy de la ciudad de Bogotá

Introducción: Actualmente existe un reconocimiento creciente de que el hogar desempeña un papel importante en varias cuestiones de higiene y salud pública. El ambiente del hogar ha sido implicado como una fuente importante de propagación de enfermedades infecciosas, y la intervención de las medidas de higiene, implican una reducción de la incidencia, especialmente en los países menos desarrollados y en poblaciones vulnerables como las gestantes. Objetivo: Evaluar la asociación entre la práctica de hábitos higiénicos de las gestantes estrato 1 y 2 de las localidades de Usaquén y Kennedy en relación a sus factores socioeconómicos. Métodos: Estudio Analítico de Corte transversal. Se realizó en las gestantes de los estratos 1 y 2 de las localidades de Usaquén y Kennedy en la ciudad de Bogotá. Se recolectaron datos referentes a factores socioeconómicos y hábitos de higiene de 141 gestantes a través de la aplicación de una encuesta. Los datos obtenidos de las variables de interés fueron procesados a través de análisis multivariado y regresión logística paramétrica y no paramétrica, con el fin de establecer si existía asociación o no entre las mismas. Resultados: Existe asociación entre el número de Nacidos vivos y la presencia de plagas (p=0.034 y Coeficiente de correlación: -1.253). Así mismo se encontró asociación habitar en cuartos rentados y la limpieza de casa general (p=0.008 y Coeficiente de correlación: 0.480). Existe una asociación entre la variable edad y el lavado de frutas (p=0.041 y Coeficiente de correlación: 0.384). Conclusiones: Existe relación entre los hábitos higiénicos y los factores socioeconómicos de las gestantes estudiadas. Existe un mayor hábito de lavado de frutas antes de ser consumidas en gestantes de mayor edad. Adicional a esto se evidencia a mayor número de hijos hay menor presencia de plagas en el hogar y mayor limpieza del hogar. Solo en un pequeño porcentaje de los hogares se evidencio una óptima limpieza, por lo cual se deben plantear más políticas para mejorar la higiene de los mismos ya que los datos reportados permanecen subóptimos en la población seleccionada.

La influencia de Miguel de Éfeso en las interpretaciones recientes del prólogo del De Motu Animalium de Aristóteles

Las interpretaciones contemporáneas del De Motu Animalium de Aristóteles dependen en gran medida del primer comentario realizado acerca del tratado, los comentarios de Miguel de Efeso del siglo XII, editados como parte de los Commentaria in Aristotelem Graeca. A pesar de que muchas propuestas revistan originalidad por sus meritorios análisis y exposición, no pueden prescindir y por lo tanto se sirven de la interpretación que hizo Miguel de ciertos pasajes. Otras interpretaciones que realizó aquél del De Motu, sin embargo, no han prosperado. Mi trabajo se propone analizar la deuda a Miguel de dos momentos, a mi parecer, importantes del prólogo del De Motu, que han dirigido los estudios recientes acerca de la importancia del tratado para el estudio de la filosofía natural de Aristóteles y el rol de la analogía en su método. Por un lado, el reconocimiento (104.6-25) de la referencia en 698a7-14 a la Física, que conlleva la determinación del objeto y del método del tratado completo, e implica, para la mayoría, por no animarme a decir todos, un distanciamiento del principio de prohibición de la metábasis. Por el otro, la transmisión del diagrama (105.3-11) correspondiente al texto de 698a22-4, del que algunos sostienen que ciertos modelos "mecanicistas" son adelantados ya en el prólogo, debido a esta repentina explicación matemática del movimiento, mientras que otros señalan la conexión con otros tratados por la descripción del movimiento mediante la figura del círculo. A través de estos dos casos pretendo evidenciar entonces la medida en que Miguel influyó y sigue influyendo la consideración reciente de este tratado de Aristóteles

La influencia de Miguel de Éfeso en las interpretaciones recientes del prólogo del De Motu Animalium de Aristóteles

Las interpretaciones contemporáneas del De Motu Animalium de Aristóteles dependen en gran medida del primer comentario realizado acerca del tratado, los comentarios de Miguel de Efeso del siglo XII, editados como parte de los Commentaria in Aristotelem Graeca. A pesar de que muchas propuestas revistan originalidad por sus meritorios análisis y exposición, no pueden prescindir y por lo tanto se sirven de la interpretación que hizo Miguel de ciertos pasajes. Otras interpretaciones que realizó aquél del De Motu, sin embargo, no han prosperado. Mi trabajo se propone analizar la deuda a Miguel de dos momentos, a mi parecer, importantes del prólogo del De Motu, que han dirigido los estudios recientes acerca de la importancia del tratado para el estudio de la filosofía natural de Aristóteles y el rol de la analogía en su método. Por un lado, el reconocimiento (104.6-25) de la referencia en 698a7-14 a la Física, que conlleva la determinación del objeto y del método del tratado completo, e implica, para la mayoría, por no animarme a decir todos, un distanciamiento del principio de prohibición de la metábasis. Por el otro, la transmisión del diagrama (105.3-11) correspondiente al texto de 698a22-4, del que algunos sostienen que ciertos modelos "mecanicistas" son adelantados ya en el prólogo, debido a esta repentina explicación matemática del movimiento, mientras que otros señalan la conexión con otros tratados por la descripción del movimiento mediante la figura del círculo. A través de estos dos casos pretendo evidenciar entonces la medida en que Miguel influyó y sigue influyendo la consideración reciente de este tratado de Aristóteles

La influencia de Miguel de Éfeso en las interpretaciones recientes del prólogo del De Motu Animalium de Aristóteles

Las interpretaciones contemporáneas del De Motu Animalium de Aristóteles dependen en gran medida del primer comentario realizado acerca del tratado, los comentarios de Miguel de Efeso del siglo XII, editados como parte de los Commentaria in Aristotelem Graeca. A pesar de que muchas propuestas revistan originalidad por sus meritorios análisis y exposición, no pueden prescindir y por lo tanto se sirven de la interpretación que hizo Miguel de ciertos pasajes. Otras interpretaciones que realizó aquél del De Motu, sin embargo, no han prosperado. Mi trabajo se propone analizar la deuda a Miguel de dos momentos, a mi parecer, importantes del prólogo del De Motu, que han dirigido los estudios recientes acerca de la importancia del tratado para el estudio de la filosofía natural de Aristóteles y el rol de la analogía en su método. Por un lado, el reconocimiento (104.6-25) de la referencia en 698a7-14 a la Física, que conlleva la determinación del objeto y del método del tratado completo, e implica, para la mayoría, por no animarme a decir todos, un distanciamiento del principio de prohibición de la metábasis. Por el otro, la transmisión del diagrama (105.3-11) correspondiente al texto de 698a22-4, del que algunos sostienen que ciertos modelos "mecanicistas" son adelantados ya en el prólogo, debido a esta repentina explicación matemática del movimiento, mientras que otros señalan la conexión con otros tratados por la descripción del movimiento mediante la figura del círculo. A través de estos dos casos pretendo evidenciar entonces la medida en que Miguel influyó y sigue influyendo la consideración reciente de este tratado de Aristóteles

The Killing of Angel Street

This article discusses the production history and social context of the 1981 Australian film, The Killing of Angel Street, directed by Donald Crombie. The article is Part 21 in a series on the National Film and Sound Archive's Kodak/Atlab Cinema Collection.

The Killing of Angel Street

Synopsis and review of the Australian feature film The Killing of Angel Street, directed by Donald Crombie.

Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

Background The Global Burden of Disease, Injuries, and Risk Factor study 2013 (GBD 2013) is the first of a series of annual updates of the GBD. Risk factor quantification, particularly of modifiable risk factors, can help to identify emerging threats to population health and opportunities for prevention. The GBD 2013 provides a timely opportunity to update the comparative risk assessment with new data for exposure, relative risks, and evidence on the appropriate counterfactual risk distribution. Methods Attributable deaths, years of life lost, years lived with disability, and disability-adjusted life-years (DALYs) have been estimated for 79 risks or clusters of risks using the GBD 2010 methods. Risk–outcome pairs meeting explicit evidence criteria were assessed for 188 countries for the period 1990–2013 by age and sex using three inputs: risk exposure, relative risks, and the theoretical minimum risk exposure level (TMREL). Risks are organised into a hierarchy with blocks of behavioural, environmental and occupational, and metabolic risks at the first level of the hierarchy. The next level in the hierarchy includes nine clusters of related risks and two individual risks, with more detail provided at levels 3 and 4 of the hierarchy. Compared with GBD 2010, six new risk factors have been added: handwashing practices, occupational exposure to trichloroethylene, childhood wasting, childhood stunting, unsafe sex, and low glomerular filtration rate. For most risks, data for exposure were synthesised with a Bayesian meta-regression method, DisMod-MR 2.0, or spatial-temporal Gaussian process regression. Relative risks were based on meta-regressions of published cohort and intervention studies. Attributable burden for clusters of risks and all risks combined took into account evidence on the mediation of some risks such as high body-mass index (BMI) through other risks such as high systolic blood pressure and high cholesterol. Findings All risks combined account for 57·2% (95% uncertainty interval [UI] 55·8–58·5) of deaths and 41·6% (40·1–43·0) of DALYs. Risks quantified account for 87·9% (86·5–89·3) of cardiovascular disease DALYs, ranging to a low of 0% for neonatal disorders and neglected tropical diseases and malaria. In terms of global DALYs in 2013, six risks or clusters of risks each caused more than 5% of DALYs: dietary risks accounting for 11·3 million deaths and 241·4 million DALYs, high systolic blood pressure for 10·4 million deaths and 208·1 million DALYs, child and maternal malnutrition for 1·7 million deaths and 176·9 million DALYs, tobacco smoke for 6·1 million deaths and 143·5 million DALYs, air pollution for 5·5 million deaths and 141·5 million DALYs, and high BMI for 4·4 million deaths and 134·0 million DALYs. Risk factor patterns vary across regions and countries and with time. In sub-Saharan Africa, the leading risk factors are child and maternal malnutrition, unsafe sex, and unsafe water, sanitation, and handwashing. In women, in nearly all countries in the Americas, north Africa, and the Middle East, and in many other high-income countries, high BMI is the leading risk factor, with high systolic blood pressure as the leading risk in most of Central and Eastern Europe and south and east Asia. For men, high systolic blood pressure or tobacco use are the leading risks in nearly all high-income countries, in north Africa and the Middle East, Europe, and Asia. For men and women, unsafe sex is the leading risk in a corridor from Kenya to South Africa. Interpretation Behavioural, environmental and occupational, and metabolic risks can explain half of global mortality and more than one-third of global DALYs providing many opportunities for prevention. Of the larger risks, the attributable burden of high BMI has increased in the past 23 years. In view of the prominence of behavioural risk factors, behavioural and social science research on interventions for these risks should be strengthened. Many prevention and primary care policy options are available now to act on key risks.

The distribution and abundance of electrosensory pores in two benthic sharks: a comparison of the wobbegong shark, Orectolobus maculatus, and the angel shark, Squatina australis

Electroreception is an ancient sense found in many aquatic animals, including sharks, which may be used in the detection of prey, predators and mates. Wobbegong sharks (Orectolobidae) and angel sharks (Squatinidae) represent two distantly related families that have independently evolved a similar dorso-ventrally compressed body form to complement their benthic ambush feeding strategy. Consequently, these groups represent useful models in which to investigate the specific morphological and physiological adaptations that are driven by the adoption of a benthic lifestyle. In this study, we compared the distribution and abundance of electrosensory pores in the spotted wobbegong shark (Orectolobus maculatus) with the Australian angel shark (Squatina australis) to determine whether both species display a similar pattern of clustering of sub-dermal electroreceptors and to further understand the functional importance of electroreception in the feeding behaviour of these benthic sharks. Orectolobus maculatus has a more complex electrosensory system than S. australis, with a higher abundance of pores and an additional cluster of electroreceptors positioned in the snout (the superficial ophthalmic cluster). Interestingly, both species possess a cluster of pores (the hyoid cluster, positioned slightly posterior to the first gill slit) more commonly found in rays, but which may be present in all benthic elasmobranchs to assist in the detection of approaching predators.

Angel Investing in Finland: An Analysis Based on Agency Theory and the Incomplete Contracting Theory

Wealthy individuals - business angels who invest a share of their net worth in entrepreneurial ventures - form an essential part of an informal venture capital market that can secure funding for entrepreneurial ventures. In Finland, business angels represent an untapped pool of capital that can contribute to fostering entrepreneurial development. In addition, business angels can bridge knowledge gaps in new business ventures by means of making their human capital available. This study has two objectives. The first is to gain an understanding of the characteristics and investment behaviour of Finnish business angels. The strongest focus here is on the due diligence procedures and their involvement post investment. The second objective is to assess whether agency theory and the incomplete contacting theory are useful theoretical lenses in the arena of business angels. To achieve the second objective, this study investigates i) how risk is mitigated in the investment process, ii) how uncertainty influences the comprehensiveness of due diligence as well as iii) how control is allocated post investment. Research hypotheses are derived from assumptions underlying agency theory and the incomplete contacting theory. The data for this study comprise interviews with 53 business angels. In terms of sample size this is the largest on Finnish business angels. The research hypotheses in this study are tested using regression analysis. This study suggests that the Finnish informal venture capital market appears to be comprised of a limited number of business angels whose style of investing much resembles their formal counterparts’. Much focus is placed on managing risks prior to making the investment by strong selectiveness and by a relatively comprehensive due diligence. The involvement is rarely on a day-to-day basis and many business angels seem to see board membership as a more suitable alternative than involvement in the operations of an entrepreneurial venture. The uncertainty involved does not seem to drive an increase in due diligence. On the contrary, it would appear that due diligence is more rigorous in safer later stage investments and when the business angels have considerable previous experience as investors. Finnish business angels’ involvement post investment is best explained by their degree of ownership in the entrepreneurial venture. It seems that when investors feel they are sufficiently rewarded, in terms of an adequate equity stake, they are willing to involve themselves actively in their investments. The lack of support for a relationship between increased uncertainty and the comprehensiveness of due diligence may partly be explained by an increasing trend towards portfolio diversification. This is triggered by a taxation system that favours investments through investment companies rather than direct investments. Many business angels appear to have substituted a specialization strategy that builds on reducing uncertainty for a diversification strategy that builds on reducing firm specific (idiosyncratic) risk by holding shares in ventures whose returns are not expected to exhibit a strong positive correlation.

Reproducción de documentación perteneciente a Miguel José Garmendia Aldaz, Asesor Jurídico y Secretario Particular del Consejero de Gobernación del Gobierno Vasco durante la Guerra en el Norte, y Mayor Jefe de la Demarcación de Fronteras en Cataluña a partir de octubre de 1938, y en enero de 1939 Delegado de Orden Público adscrito a la Comandancia Militar de Figueras.

Fecha: 10-10-1936/31-1-1939 / Unidad de instalación: Carpeta 25 - Expediente 21 / Nº de pág.: 33 (28 mecanografiadas, 5 manuscritas)