The putative telomerase reverse transcriptase component of Leishmania amazonensis: gene cloning and characterization

The Leishmania amazonensis telomerase gene was cloned by a polymerase chain reaction-based strategy using primers designed from a Leishmania major sequence that shared similarities with conserved telomerase motifs. The genes from three other species were cloned for comparative purposes. A ClustalW multiple-sequence alignment demonstrated that the Leishmania telomerases show greater homology with each other than with the proteins of other kinetoplastids and eukaryotes. Characterization experiments indicated that the putative Leishmania telomerase gene was probably in single copy and located in the largest chromosomes. A single messenger ribonucleic acid transcript was found in promastigotes. Phylogenetic analysis suggested that Leishmania telomerase might represent a liaison between the oldest and the newest branches of telomerases.

Influence of HLA-DRB-1 alleles on the production of antibody against CSP, MSP-1, AMA-1, and DBP in Brazilian individuals naturally infected with Plasmodium vivax

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

A notícia participativa e o reposicionamento das fontes - estudo de caso: São José do Rio Preto

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A palavra arbitrária: estudo e tradução de Fenêtres dormantes et porte sur le toit, de René Char

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A presença da fábula, do lirismo e da narrativa em Le Bestiaire ou Cortège d'Orphée de Guillaume Apollinaire

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Conflitos teológicos e políticos da Igreja Católica no Brasil presentes nos artigos das revistas Hora Presente e Permanência (1968-1974)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Aspectos do realismo: em torno de Memórias de um sargento de milícias

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Aspectos filogenéticos e sorológicos envolvidos na caracterização das variantes da proteína circunsporozoítica de Palsmodium vivax

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação da resposta de anticorpos contra antígenos de Plasmodium vivax relacionada a fatores genéticos do parasito e do hospedeiro humano

Pós-graduação em Genética - IBILCE

Comparative recognition by human IgG antibodies of recombinant proteins representing three asexual erythrocytic stage vaccine candidates of Plasmodium vivax

In previous immuno-epidemiological studies of the naturally acquired antibody responses to merozoite surface protein-1 (MSP-1) of Plasmodium vivax, we had evidence that the responses to distinct erythrocytic stage antigens could be differentially regulated. The present study was designed to compare the antibody response to three asexual erythrocytic stage antigens vaccine candidates of P. vivax. Recombinant proteins representing the 19 kDa C-terminal region of MSP-1(PvMSP19), apical membrane antigen n-1 ectodomain (PvAMA-1), and the region II of duffy binding protein (PvDBP-RII) were compared in their ability to bind to IgG antibodies of serum samples collected from 220 individuals from the state of Pará, in the North of Brazil. During patent infection with P. vivax, the frequency of individuals with IgG antibodies to PvMSP119, PvAMA-1, and PvDBP-RII were 95, 72.7, and 44.5% respectively. Although the frequency of responders to PvDBP-RII was lower, this frequency increased in individuals following multiple malarial infections. Individually, the specific antibody levels did not decline significantly nine months after treatment, except to PvMSP119. Our results further confirm a complex regulation of the immune response to distinct blood stage antigens. The reason for that is presently unknown but it may contribute to the high risk of re-infection in individuals living in the endemic areas.

Hypothermia and Early Neonatal Mortality in Preterm Infants

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Benefits of soil carbon: report on the outcomes of an international scientific committee on problems of the environment rapid assessment workshop

A Scientific Committee on Problems of the Environment Rapid Assessment (SCOPE-RAP) workshop was held on 18-22 March 2013. This workshop was hosted by the European Commission, JRC Centre at Ispra, Italy, and brought together 40 leading experts from Africa, Asia, Europe and North and South America to create four synthesis chapters aimed at identifying knowledge gaps, research requirements, and policy innovations. Given the forthcoming publication by CABI of a book volume of the outcomes of the SCOPE-RAP in 2014, this workshop report provides an update on the global societal challenge of soil carbon management and some of the main issues and solutions that were identified in the four working sessions.

From Potential to Implementation: an innovation framework to realize the benefits of soil carbon

This chapter addresses the mismatch between existing knowledge, techniques and management methods for improved soil carbon management and deficits in its implementation. The paper gives a short overview of the evolution of the concept of soil carbon, which illustrates the interactions between scientific, industrial, technical, societal and economic change. It then goes on to show that sufficient techniques are available for the large-scale implementation of soil organic carbon (SOC) sequestration. A subsequent analysis of the bottlenecks that prevent implementation identifies where issues need to be addressed in order to enable robust, integrated and sustainable SOC management strategies.

A recepção crítica de J.-K. Huysmans em periódicos no Brasil (1884 – 2013)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

学術機関リポジトリでのオリジナルコンテンツの公開

学術機関リポジトリ（Institutional Repository、IR）は主に、学術雑誌、記念論文集、論文集など、他の場所で公開済みの学術的コンテンツを再公開する手段として開発され促進されてきた。本書では、他ではまだ公開していない資料の最初の公開場所にIRを使用する方法について考察し、学術的公開のための発展性のある「第一手段」として、また従来の商業出版社または大学出版局の代わりとなる既存の手段としてIRを利用できる可能性を評価する。Serials Review 2008; 34:27-30. Translation courtesy of Library Liaison Team, National Institute of Informatics, Japan, Cyber Science Infrastructure Development Department, Scholarly and Academic Information Division.