Industrial conciliation : report of the proceedings of the conference, held under the auspices of the National Civic Federation, at the rooms of the Board of Trade and Transportation in New York, December 16 and 17, 1901.

Includes index.

A bibliography of the first editions in book form of the writings of Charles and Mary Lamb published prior to Charles Lamb's death in 1834,

"Appendix: The books of the two John Lambs": p. 195-203.

Minutes of the Bury Presbyterian classis, 1647-1657/

Appendix: I. The minutes of the Nottingham classis, 1656-60. II. Minutes of the Cornwall classis, 1655-8. III. Minutes of the Cambridge classis, Jany 20, 1656/7 to July 13, 1658. IV. An account of the ministers mentioned in the Bury minutes.

Polychronicon Ranulphi Higden monachi Cestrensis; together with the English translations of John Trevisa and of an unknown writer of the fifteenth century.

The first book comprises a brief description of the two countries of the known world, and a more particular account of Great Britain.

Organic chemistry; or, Chemistry of the carbon compounds,

I. Chemistry of the aliphatic series newly tr. and rev. from the German ed. (after Prof. Edgar F. Smiths's 3d American ed.) by Percy E. Spielman. 1916. ...II. Chemistry of the carbocyclic compounds, tr. from the 11th German ed., by E.E. Fournier d'Albe. 1922. ...III. Heterocyclic compounds, Tr. from the 11th German ed., by E.E. Fournier d'Albe. 1923.

The Ante-Nicene fathers : translations of the writings of the fathers down to A.D. 325 /

First published under title: Ante-Nicene Christian library, Edinburgh, 1867-97.

The origin of the difference in the superconducting critical temperatures of the beta(H) and beta(L) phases of (BEDT-TTF)(2)I-3

Incommensurate lattice fluctuations are present in the beta(L) phase (T-c similar to 1.5 K) of ET2I3 (where ET is BEDT-TTF - bis(ethylenedithio)tetrathiafulvalene) but are absent in the beta(H) phase (T-c similar to 7 K). We propose that the disorder in the conformational degrees of freedom of the terminal ethylene groups of the ET molecules, which is required to stabilise the lattice fluctuations, increases the quasiparticle scattering rate and that this leads to the observed difference in the Superconducting critical temperatures, T-c, of the two phases. We calculate the dependence of T-c on the interlayer residual resistivity. Our theory has no free parameters. Our predictions are shown to be consistent with experiment. We describe experiments to conclusively test our hypothesis.

Structure of the N-terminal domain of Escherichia coli glutamine synthetase adenylyltransferase

We report the crystal structure of the N-terminal domain of Escherichia coli adenylyltransferase that catalyzes the reversible nucleotidylation of glutamine synthetase (GS), a key enzyme in nitrogen assimilation. This domain (AT-N440) catalyzes the deadenylylation and subsequent activation of GS. The structure has been divided into three subdomains, two of which bear some similarity to kanamycin nucleotidyltransferase (KNT). However, the orientation of the two domains in AT-N440 differs from that in KNT. The active site of AT-N440 has been identified on the basis of structural comparisons with KNT, DNA polymerase beta, and polyadenylate polymerase. AT-N440 has a cluster of metal binding residues that are conserved in polbeta-like nucleotidyl transferases. The location of residues conserved in all ATase sequences was found to cluster around the active site. Many of these residues are very likely to play a role in catalysis, substrate binding, or effector binding.

The role of drinking restraint in alcohol dependence: validation of the temptation and restraint inventory in an alcohol dependent sample

Objective: The Temptation and Restraint Inventory (TRI) is commonly used to measure drinking restraint in relation to problem drinking behavior. However, as yet the TRI has not been validated in a clinical group with alcohol dependence. Method: Male (n = 111) and female (n = 57) inpatients with DSM-IV diagnosed alcohol dependence completed the TRI and measures of problem drinking severity, including the Alcohol Dependence Scale and the quantity, frequency and week total of alcohol consumed. Results: The factor structure of the TRI was replicated in the alcohol dependent sample. Cognitive Emotional Preoccupation (CEP), one of the two higher order factors of the TRI, demonstrated sound predictive power toward all dependence severity indices. The other higher order factor, Cognitive Behavioral Control (CBC), was related to frequency of drinking. There was limited support for the CEP/CBC interactional model of drinking restraint. Conclusions: Although the construct validity of the TRI was sound, the measure appears more useful in understanding the development, maintenance and severity of alcohol-related problems in nondependent drinkers. The TRI may show promise in detecting either continuous drinking or heavy episodic type dependent drinkers.

Mass uptake study of the diffusion of water and SBF into poly(2-hydroxyethyl methacrylate-co-tetrahydrofurfuryI methacrylate) containing aspirin or vitamin B-12

The ingress of water and Kokubo simulated body fluid (SBF) into poly (2-hydroxyethyl methacrylate) (PHEMA), and its co-polymers with tetrahydrofurduryl methacrylate (THFMA), loaded with either one of two model drugs, vitamin 1312 or aspirin, was studied by mass uptake over the temperature range 298-318 K. The polymers were studied as cylinders and were loaded with either 5 wt% or 10 wt% of the drugs. From DSC studies it was observed that vitamin B-12 behaved as a physical cross-linker restricting chain segmental mobility, and so had a small anti-plasticisation effect on PHEMA and the co-polymers rich in HEMA, but almost no effect on the T-g of co-polymers rich in THFMA. On the other hand, aspirin exhibited a plasticising effect on PHEMA and the copolymers. All of the polymers were found to absorb water and SBF according to a Fickian diffusion mechanism. The polymers were all found to swell to a greater extent in SBF than in water, which was attributed to the presence of Tris buffer in the SBF. The sorptions of the two penetrants were found to follow Fickian kinetics in all cases and the diffusion coefficients at 310 K for SBF were found to be smaller than those for water, except for the polymers containing aspirin where the diffusion coefficients were higher than for the other systems. For example, for sorption into PHEMA the diffusion coefficient for water was 1.41 X 10(-11) m(2)/s and for SBF was 0.79 x 10-11 m(2)/s, but in the presence of 5 wt% aspirin the corresponding values were 1.27 x 10(-1)1 m(2)/s and 1.25 x 10(-11) m(2)/s, respectively. The corresponding values for PHEMA loaded with 5 wt% B-12 were 1.25 x 10(-11) m(2)/s and 0.74 x 10(-11) m(2)/s, respectively.

Molecular basis of intramolecular electron transfer in sulfite-oxidizing enzymes is revealed by high resolution structure of a heterodimeric complex of the catalytic molybdopterin subunit and a c-type cytochrome subunit

Sulfite-oxidizing molybdoenzymes convert the highly reactive and therefore toxic sulfite to sulfate and have been identified in insects, animals, plants, and bacteria. Although the well studied enzymes from higher animals serve to detoxify sulfite that arises from the catabolism of sulfur-containing amino acids, the bacterial enzymes have a central role in converting sulfite formed during dissimilatory oxidation of reduced sulfur compounds. Here we describe the structure of the Starkeya novella sulfite dehydrogenase, a heterodimeric complex of the catalytic molybdopterin subunit and a c-type cytochrome subunit, that reveals the molecular mechanism of intramolecular electron transfer in sulfite-oxidizing enzymes. The close approach of the two redox centers in the protein complex (Mo-Fe distance 16.6 angstrom) allows for rapid electron transfer via tunnelling or aided by the protein environment. The high resolution structure of the complex has allowed the identification of potential through-bond pathways for electron transfer including a direct link via Arg-55A and/or an aromatic-mediated pathway. A potential site of electron transfer to an external acceptor cytochrome c was also identified on the SorB subunit on the opposite side to the interaction with the catalytic SorA subunit.

Upper Devonian biostratigraphy of the Iberian Pyrite Belt, southwest Spain Part One: Miospores

The Iberian Pyrite Belt (IPB), which forms part of the Variscan orogenic massif, is renowned for the magnitude and extent of its massive sulfide mineralization. The stratigraphic record of the IPB consists of Upper Palaeozoic sedimentary and igneous rocks. In ascending order, these comprise the thick Phyllite-Quartzite Group attributed to the Middle and Upper Devonian and characterized by shales and quartzites with conglomeratic and carbonate intercalations towards the top; the appreciably thinner Volcano-Sedimentary Complex, a heterogeneous uppermost Devonian-Mississippian unit embodying diverse volcanic, subvolcanic, and sedimentary rocks that host the massive sulfide deposits; and the shaly and sandy, turbiditic Culm Group (Carboniferous). This entire succession was folded and faulted during the Asturian phase of the Variscan Orogeny that gave rise to a thin-skinned type structure. The present study constitutes a detailed blostratigraphic investigation of palynologically productive samples representative of the Phyllite-Quartzite Group and the basal (anoxic) portion of the Volcano-Sedimentary Complex. These were collected from surface and mine exposures variously located in the Spanish part of the IPB; out of 282 samples processed, 117 proved to be productive palynologically. The aim of this project is to provide comprehensive palynostratigraphic data applicable to precise dating and correlation of the IPB's stratigraphic succession (i.e., of the two sampled lithostratigraphic units), which has hitherto been investigated biostratigraphically on a relatively localized basis. The results are incorporated in two successive parts. The first of these, i. e., the present paper, focuses on the systematic analysis of the terrestrial (miospore) component of the palynological assemblages. The second part, devoted to the marine, organic-walled microphytoplankton (acritarchs and prasinophytes), will evaluate the stratigraphic significance of the IPB palynofloras and their application to elucidating the geological history of the region. In the systematic-descriptive section, which occupies the bulk of this paper, 55 species of trilete miospores are described and are allocated among 34 genera, two of which (Cristicavatispora and Epigruspora) are newly instituted herein. The majority of the species are either positively identifiable or closely affiliable with previously named species. The nine newly established species are as follows: Camptozonotriletes confertus, Indotriradites diversispinosus, Cristicavatispora dispersa (type species), Epigruspora regularis (type species), Ancyrospora? implicata, Endosporites tuberosus, Rugospora explicata, Spelaeotriletes plicatus, and Teichertospora iberica.

Flight data analysis of the HyShot 2 scramjet flight experiment

The development of scramjet propulsion for alternative launch and payload delivery capabilities has been composed largely of ground experiments for the last 40 years. With the goal of validating the use of short duration ground test facilities, a ballistic reentry vehicle experiment called HyShot was devised to achieve supersonic combustion in flight above Mach 7.5. It consisted of a double wedge intake and two back-to-back constant area combustors; one supplied with hydrogen fuel at an equivalence ratio of 0.34 and the other unfueled. Of the two flights conducted, HyShot 1 failed to reach the desired altitude due to booster failure, whereas HyShot 2 successfully accomplished both the desired trajectory and satisfactory scramjet operation. Postflight data analysis of HyShot 2 confirmed the presence of supersonic combustion during the approximately 3 s test window at altitudes between 35 and 29 km. Reasonable correlation between flight and some preflight shock tunnel tests was observed.

Quantum entanglement in the two-impurity Kondo model

In order to quantify quantum entanglement in two-impurity Kondo systems, we calculate the concurrence, negativity, and von Neumann entropy. The entanglement of the two Kondo impurities is shown to be determined by two competing many-body effects, namely the Kondo effect and the Ruderman-Kittel-Kasuya-Yosida (RKKY) interaction, I. Due to the spin-rotational invariance of the ground state, the concurrence and negativity are uniquely determined by the spin-spin correlation between the impurities. It is found that there exists a critical minimum value of the antiferromagnetic correlation between the impurity spins which is necessary for entanglement of the two impurity spins. The critical value is discussed in relation with the unstable fixed point in the two-impurity Kondo problem. Specifically, at the fixed point there is no entanglement between the impurity spins. Entanglement will only be created [and quantum information processing (QIP) will only be possible] if the RKKY interaction exchange energy, I, is at least several times larger than the Kondo temperature, T-K. Quantitative criteria for QIP are given in terms of the impurity spin-spin correlation.

Structural and functional characterization of the conserved salt bridge in mammalian Paneth cell alpha-defensins - Solution structures of mouse cryptdin-4 AND (E15D)-cryptdin-4

Defensins are mediators of mammalian innate immunity, and knowledge of their structure-function relationships is essential for understanding their mechanisms of action. We report here the NMR solution structures of the mouse Paneth cell α-defensin cryptdin-4 (Crp4) and a mutant (E15D)-Crp4 peptide, in which a conserved Glu15 residue was replaced by Asp. Structural analysis of the two peptides confirms the involvement of this Glu in a conserved salt bridge that is removed in the mutant because of the shortened side chain. Despite disruption of this structural feature, the peptide variant retains a well defined native fold because of a rearrangement of side chains, which result in compensating favorable interactions. Furthermore, salt bridge-deficient Crp4 mutants were tested for bactericidal effects and resistance to proteolytic degradation, and all of the variants had similar bactericidal activities and stability to proteolysis. These findings support the conclusion that the function of the conserved salt bridge in Crp4 is not linked to bactericidal activity or proteolytic stability of the mature peptide.