Professor Drews teaching class in basic public administration

Prof. Lederle's siminar in administrative organization & management. Students are from Dept. of Justice, Bur. of Forestry, Bureau of Public Health & Philippine Airlines, a government corporation.

Supplementary analysis of Report on administration issued by Public Administration Service [Chicago]

Caption title.

Technical assistance in public administration, the domestic role: II, a report on the Brazilian program, University of Souther California, 1952-54,

Mode of access: Internet.

Terminal report [to the International Cooperation Administration] on the contract concerning public administration in the University of San Andrés.

Mode of access: Internet.

Report of a meeting on technical cooperation in public administration in dependent territories, New York, N.Y., 20 May 1954.

Mode of access: Internet.

Reflections on public administration,

Mode of access: Internet.

Standards and techniques of public administration with special reference to technical assistance for under-developed countries; report.

Mode of access: Internet.

Public administration and policy development, a case book.

At head of title: The Inter-university Case Program.

Year book of the Tecumseh public schools : officers, teachers and graduates, with announcements, calendar and courses of study for ... /

Mode of access: Internet.

Annual announcement of the Tecumseh Public Schools ... : organization, examination and expenses, courses of study, rules and regulations.

Mode of access: Internet.

Acute cadmium chloride administration induces hepatic and renal cytochrome P450 2A5 in the mouse

Modulation of the cytochrome P450 (CYP) monooxygenase system by cadmium was investigated in male, adult DBA/2J mice treated with a single dose (16 Amol/kg body weight, i.p.) of cadmium chloride (CdCl2) at various time points. The total CYP content of kidney microsomes started to decrease 4 hours earlier than in the liver (P < 0.05), with maximal decreases at 24 hours of 56% and 85% in the liver and kidney, respectively. In contrast, both hepatic and renal coumarin 7-hydroxylase (COH) activity (indicative of CYP2A5 activity) relative to total CYP content started to progressively increase at 8 hours, with renal activity 61 times higher than the hepatic activity. Maximum increases were observed, 15-fold in the liver and 64-fold in the kidney after 24 hours. Liver and kidney CYP2A5 mRNA levels increased maximally 12 and 4 hours after treatment, respectively and decreased to almost half 6 hours later. In contrast, kidney and liver CYP2A5 protein levels increased maximally at 18 and 24 hours. This study demonstrates that hepatic and renal CYP2A5 is upregulated by cadmium with a faster response in the kidney than in the liver. This observation is concordant with the fact that kidney is the target organ for cadmium toxicity. The observed increase in the mRNA but not in protein levels after maximal induction suggests involvement of post-transcriptional mechanisms in the regulation of CYP2A5 expression by cadmium.

Network structures: Working differently and changing expectations

There is a growing need for innovative methods of dealing with complex, social problems. New types of collaborative efforts have emerged as a result of the inability of more traditional bureaucratic hierarchical arrangements such as departmental program, to resolve these problems. Network structures are one such arrangement that Is at the forefront of this movement. Although collaboration through network structures establishes an innovative response to dealing with social issues, there remains an expectation that outcomes and processes are based on traditional ways of working. It is necessary for practitioners and policy makers alike to begin to understand the realities of what can be expected from network structures in order to maximize the benefits of these unique mechanisms.