907 resultados para Cultures locales de vaccination


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Incluye bibliografía

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Pós-graduação em Zootecnia - FMVZ

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1. La conferencia sobre “Vínculos entre proveedores de servicios locales y las cadenas globales de valor” se enmarcó en la Reunión titulada “Internacionalización e innovación de servicios: nuevas fuentes del desarrollo productivo en América Latina”, organizada por la Comisión Económica para América Latina y el Caribe (CEPAL), el Colegio de México (COLMEX), el Colegio de la Frontera Norte (COLEF), el Banco Interamericano de Desarrollo (BID), la Organización para la Cooperación y el Desarrollo Económico (OECD), la Conferencia de las Naciones Unidas sobre Comercio y Desarrollo (UNCTAD) y el World Trade Institute (WTI). 2. Los servicios desempeñan un papel predominante en las estructuras económicas de América Latina, que se expresa por su gran peso económico (más del 50% del PIB) y por la generación de empleo (más de la mitad del total), junto con una proporción creciente en el comercio internacional, sobre todo cuando este último se mide por valor agregado. Los servicios, lejos de constituirse como un sector autónomo con respecto al industrial, deben su crecimiento a la progresiva racionalización iniciada durante los años ochenta en la cadena de producción manufacturera. En la actualidad, la competitividad de los países, vinculada con su capacidad para atraer o conservar en su territorio parte del valor generado en el sistema mundial, depende del grado de escalamiento del sector servicios en la cadena de valor global. 3. El papel que tienen los servicios genera una serie de retos y oportunidades para el diseño de políticas públicas y para los estudios académicos, principalmente en lo relacionado con: el desempeño de la productividad en los servicios; la participación en cadenas globales de valor y en su escalamiento; el impacto de los marcos regulatorios en el desarrollo del sector; su vinculación con los procesos de innovación, y la calidad de los empleos generados. El objetivo de esta reunión fue dar respuesta a algunos de estos planteamientos y promover el diálogo entre investigadores y diseñadores de política pública. En seguida, se incluye la información sobre la organización, la dinámica y las conclusiones de la reunión.

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A linhagem celular Hep-2 é formada por células de carcinoma da laringe e é muito utilizada em modelos de carcinogênese e mutagenêse. Para avaliar o potencial proliferativo desta linhagem, desenvolvemos uma metodologia citogenética (técnica do sobrenadante) para obtenção de metáfases a partir de células que, ao entrarem em mitose, perdem adesão celular, ficando em suspensão no meio de cultura. Através deste procedimento, foram contadas 2000 células, correspondendo a um índice mitótico (IM) de 22.2% . Apesar de o IM obtido por esta técnica não ter sido estatisticamente diferente do IM obtido por outras metodologias citogenéticas clássicas, a técnica do sobrenadante é vantajosa porque elimina o uso de alguns reagentes utilizados na obtenção de metáfases e também diminui o consumo de reagentes de manutenção desta linhagem.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Coagulase-negative staphylococci (CoNS) are the microorganisms most frequently isolated from clinical samples and are commonly found in neonatal blood cultures. Oxacillin is an alternative treatment of choice for CoNS infections; however, resistance to oxacillin can have a substantial impact on healthcare by adversely affecting morbidity and mortality. The objective of this study was to detect and characterise oxacillin-resistant CoNS strains in blood cultures of newborns hospitalised at the neonatal ward of the University Hospital of the Faculty of Medicine of Botucatu. One hundred CoNS strains were isolated and the mecA gene was detected in 69 of the CoNS strains, including 73.2% of Staphylococcus epidermidis strains, 85.7% of Staphylococcus haemolyticus strains, 28.6% of Staphylococcus hominis strains and 50% of Staphylococcus lugdunensis strains. Among these oxacillin-resistant CoNS strains, staphylococcal cassette chromosome mec (SCCmec) type I was identified in 24.6%, type II in 4.3%, type III in 56.5% and type IV in 14.5% of the strains. The data revealed an increase in the percentage of CoNS strains isolated from blood cultures from 1991-2009. Furthermore, a predominant SCCmec profile of the oxacillin-resistant CoNS strains isolated from neonatal intensive care units was identified with a prevalence of SCCmec types found in hospital-acquired strains.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Background. Rubella vaccination is contraindicated during pregnancy. During mass immunization of women of childbearing age against rubella, women unknowingly pregnant may be vaccinated. To evaluate the effects of rubella vaccination during pregnancy, the Brazilian state of Sao Paulo conducted a follow-up study of pregnant women vaccinated during a rubella campaign in 2001.Methods. Women vaccinated during pregnancy were reported to a national surveillance system. In the state of Sao Paulo, follow-up of vaccinated women included household interviews. Serum samples from vaccinated women were tested for antirubella antibodies to classify susceptibility to rubella infection. Children born to susceptible mothers were tested for evidence of congenital rubella infection and evaluated for signs of congenital rubella syndrome.Results. The Sao Paulo State Health Department received 6473 notifications of women vaccinated during pregnancy. Serology performed for 5580 women identified 811 (15%) that were previously susceptible. Incidence of spontaneous abortion or stillbirth among previously susceptible vaccinated women was similar to women with prior immunity. Twenty-seven (4.7%) of 580 newborns tested had evidence of congenital rubella infection; none had congenital rubella syndrome.Conclusions. Mass rubella vaccination of women of childbearing age was not associated with adverse birth outcomes or congenital rubella syndrome among children born to women vaccinated during pregnancy.