[Concurrent de la course motocycliste Paris-Reims-Paris, conduisant un side-car Rover, 6 juillet 1919] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 54751

The antioxidant effect of β-caryophyllene protects rat liver from carbon tetrachloride-induced fibrosis by inhibiting hepatic stellate cell activation.

Plant-based whole foods provide thousands of bioactive metabolites to the human diet that reduce the risk of developing chronic diseases. β-Caryophyllene (CAR) is a common constituent of the essential oil of numerous plants, vegetables, fruits and medicinal herbs, and has been used as a flavouring agent since the 1930 s. Here, we report the antioxidant activity of CAR, its protective effect on liver fibrosis and its inhibitory capacity on hepatic stellate cell (HSC) activation. CAR was tested for the inhibition of lipid peroxidation and as a free radical scavenger. CAR had higher inhibitory capacity on lipid peroxidation than probucol, α-humulene and α-tocopherol. Also, CAR showed high scavenging activities against hydroxyl radical and superoxide anion. The activity of 5-lipoxygenase, an enzyme that actively participates in fibrogenesis, was significantly inhibited by CAR. Carbon tetrachloride-treated rats received CAR at 2, 20 and 200 mg/kg. CAR significantly improved liver structure, and reduced fibrosis and the expression of Col1a1, Tgfb1 and Timp1 genes. Oxidative stress was used to establish a model of HSC activation with overproduction of extracellular matrix proteins. CAR (1 and 10 μm) increased cell viability and significantly reduced the expression of fibrotic marker genes. CAR, a sesquiterpene present in numerous plants and foods, is as a natural antioxidant that reduces carbon tetrachloride-mediated liver fibrosis and inhibits hepatic cell activation.

Catellas/Georges Leroy, 750 cm3 [le side-car n° 25 au départ de la course Paris-Reims-Paris] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 54754

Lecomte sur Rover, 500 cmc [course motocycliste Paris-Reims-Paris, side-car, 6 juillet 1919] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 54746

Monitorización de estructuras y gestión de edificios: Building Management

El objetivo del proyecto es realizar un sistema de monitorizacion de estructuras y gestión de edificios para controlar en todo momento el estado de los mismos. Se controlará cualquier aspecto que pueda afectar al edificio, como es la temperatura, la humedad, la oscilación del edificio; además de otros aspectos que ayuden a que el edificio se mantenga seguro y en perfecto estado como alarmas de seguridad, luminosidad, etc.

Designing business models of cloud platforms

Cloud computing and its three facets (Software as a Service (SaaS), Platform as a Service (PaaS), and Infrastructure as a Service (IaaS)) are terms that denote new developments in the software industry. In particular, PaaS solutions, also referred to as cloud platforms, are changing the way software is being produced, distributed, consumed, and priced. Software vendors have started considering cloud platforms as a strategic option but are battling to redefine their offerings to embrace PaaS. In contrast to SaaS and IaaS, PaaS allows for value co-creation with partners to develop complementary components and applications. It thus requires multisided business models that bring together two or more distinct customer segments. Understanding how to design PaaS business models to establish a flourishing ecosystem is crucial for software vendors. This doctoral thesis aims to address this issue in three interrelated research parts. First, based on case study research, the thesis provides a deeper understanding of current PaaS business models and their evolution. Second, it analyses and simulates consumers' preferences regarding PaaS business models, using a conjoint approach to find out what determines the choice of cloud platforms. Finally, building on the previous research outcomes, the third part introduces a design theory for the emerging class of PaaS business models, which is grounded on an extensive action design research study with a large European software vendor. Understanding PaaS business models from a market as well as a consumer perspective will, together with the design theory, inform and guide decision makers in their business model innovation plans. It also closes gaps in the research related to PaaS business model design and more generally related to platform business models.

[Paul] Péan, sur Peugeot [course Paris-Reims-Paris, moto 6 HP avec side-car, 6 juillet 1919] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 54734

Pasola sur A.J. S. [le side-car n° 31 au départ de la course Paris-Reims-Paris] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 54756

Automatització d’una fàbrica de pinso

Les produccions ramaderes en el seu conjunt no es podrien atendre en el món actual sensela participació de la indústria del pinso compost. L’alternativa de treballar en base a pinsosimple o senzillament amb cereals o altres primeres matèries individuals, faria inviablel’abastiment en qualitat i quantitat del que es consumeix.La realització de pinso compost és el resultat de la barreja de variades substànciesalimentàries, sals minerals i fàrmacs per a la nutrició del bestiar.Les fàbriques de pinso aglutinen diverses explotacions agràries, garantint diàriament un treballcontinu sense grans fluctuacions, una dosificació exacta depenent de la recepta que hagiprogramat el veterinari i flexibilitat davant els canvis.Aquestes fàbriques requereixen de maquinària més precisa per fer front a les molt variades receptesnutricionals depenent del tipus de bestiar i de l’època estacional.La dimensió de les fàbriques també serà més gran, per poder atendre la major demanda decomandes i assegurar una producció de qualitat.Moltes fàbriques de pinso són velles o provenen d’antigues explotacions ramaderesreconvertides, les quals d’acord amb l’actual necessitat de control de qualitat, efectivitat irapidesa s’han modernitzat o s’estan reciclant, car el propi mercat i competència els estàprecipitant a fer-ho.Una fàbrica moderna de pinso és una planta de processos que incorpora tecnologies defabricació i control, iguals que qualsevol indústria.S’ha de dissenyar per produir pinso compost de forma competitiva i tindre en tot momentcapacitat per controlar els seus processos, així com assegurar la qualitat del producte final,tant a nivell nutricional com el sanitari.Això s’ha de realitzar amb el màxim nivell de seguretat pels operaris, alhora que s’elimininels efectes de contaminació ambiental, com la pols i el soroll.Amb l’automatització de la fàbrica ja no es repetiran les errades per l’accionament demotors, malmetent una dosificació i perdent un temps molt valuós

Building energy saving techniques and indoor air quality : a dilemma

In European countries and North America, people spend 80 to 90% of time inside buildings and thus breathe indoor air. In Switzerland, special attention has been devoted to the 16 stations of the national network of observation of atmospheric pollutants (NABEL). The results indicate a reduction in outdoor pollution over the last ten years. With such a decrease in pollution over these ten years the question becomes: how can we explain an increase of diseases? Indoor pollution can be the cause. Indoor contaminants that may create indoor air quality (IAQ) problems come from a variety of sources. These can include inadequate ventilation, temperature and humidity dysfunction, and volatile organic compounds (VOCs). The health effects from these contaminants are varied and can range from discomfort, irritation and respiratory diseases to cancer. Among such contaminants, environmental tobacco smoke (ETS) could be considered the most important in terms of both health effects and engineering controls of ventilation. To perform indoor pollution monitoring, several selected ETS tracers can be used including carbon monoxide (CO), carbon dioxide (CO2), respirable particles (RSP), condensate, nicotine, polycyclic aromatic hydrocarbons (PAHs), nitrosamines, etc. In this paper, some examples are presented of IAQ problems that have occurred following the renewal of buildings and energy saving concerns. Using industrial hygiene sampling techniques and focussing on selected priority pollutants used as tracers, various problems have been identified and solutions proposed. [Author]

The building blocks of international ecological footprint inequality: a regression-based decomposition

This paper performs an empirical Decomposition of International Inequality in Ecological Footprint in order to quantify to what extent explanatory variables such as a country’s affluence, economic structure, demographic characteristics, climate and technology contributed to international differences in terms of natural resource consumption during the period 1993-2007. We use a Regression-Based Inequality Decomposition approach. As a result, the methodology extends qualitatively the results obtained in standard environmental impact regressions as it comprehends further social dimensions of the Sustainable Development concept, i.e. equity within generations. The results obtained point to prioritizing policies that take into account both future and present generations.

Academic Building Revenue Bond Funds, June 30, 2002

State University Audit Report

Forensic intelligence framework. Part II: study of the main generic building blocks and challenges through the examples of illicit drugs and false identity documents monitoring

The development of forensic intelligence relies on the expression of suitable models that better represent the contribution of forensic intelligence in relation to the criminal justice system, policing and security. Such models assist in comparing and evaluating methods and new technologies, provide transparency and foster the development of new applications. Interestingly, strong similarities between two separate projects focusing on specific forensic science areas were recently observed. These observations have led to the induction of a general model (Part I) that could guide the use of any forensic science case data in an intelligence perspective. The present article builds upon this general approach by focusing on decisional and organisational issues. The article investigates the comparison process and evaluation system that lay at the heart of the forensic intelligence framework, advocating scientific decision criteria and a structured but flexible and dynamic architecture. These building blocks are crucial and clearly lay within the expertise of forensic scientists. However, it is only part of the problem. Forensic intelligence includes other blocks with their respective interactions, decision points and tensions (e.g. regarding how to guide detection and how to integrate forensic information with other information). Formalising these blocks identifies many questions and potential answers. Addressing these questions is essential for the progress of the discipline. Such a process requires clarifying the role and place of the forensic scientist within the whole process and their relationship to other stakeholders.

Major Empson sur AV, pesage de Paris-Nice [cycle-car, 1100 cmc, course Paris-Nice] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 57958

Baudelocque sur Morgan [cycle-car, 1100 cmc, course Paris-Nice] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 57960