Proceedings [of] Annual Meetings of the American Society of Sanitary Engineering

Title Varies: 1906-09, Official Book of Convention Proceedings (Cover-Title; Proceedings) 1910-11, Report of Proceedings of Annual Meetings of the American Society of Inspectors of Plumbing and Sanitary Engineers; 1915-1917 Proceedings Annual Meetings of the American Society of Sanitary Engineers

Saddle and camp in the Rockies; an expert's picture of game conditions in the heart of our hunting country,

Mode of access: Internet.

Camping and character : a camp experiment in character education /

Description of work at Camp Ahmek. cf. Pref.

Records of the meetings of the School Committee of the City of Providence.

Imprint varies.

Proceedings of the meetings for the years, 1908, 1909, 1910.

Mode of access: Internet.

Return of Frank R. Stockton : ... stories and letters which cannot fail to convince the reader that Frank R. Stockton still lives and writes through the instrumentality of Miss Etta de Camp.

Frontispiece with portrait of author.

Camp yr Adroddwr.

Mode of access: Internet.

Report of the meetings for organization of the Minnesota State Bar Association, held at St. Paul, April 3d and June 18th, 1883.

Mode of access: Internet.

Gloucestershire friends: poems from a German prison camp,

"First published in 1917; second impression April 1918."

"Management of private corporations" ... with notes on organization, meetings and records, giving decisions of the courts touching the acts of corporations, boards of directors and corporation officers.

Mode of access: Internet.

Corporate meetings, minutes, and resolutions,

Mode of access: Internet.

Transactions of the annual meetings of the Western literary institute and college of professional teachers

Mode of access: Internet.

Activation of the cAMP pathway by variant human MC1R alleles expressed in HEK and in melanoma cells

alpha-Melanocyte-stimulating hormone (alpha-MSH) activates the melanocortin-1 receptor (MC1R) on melanocytes to promote a switch from red/yellow pheomelanin synthesis to darker eumelanins via positive coupling to adenylate cyclase. The human MC1R locus is highly polymorphic with the specific variants associated with red hair and fair skin (RHC phenotype) postulated to be loss-of-function receptors. We have examined the ability of MC1R variants to activate the cAMP pathway in stably transfected REK293 cells. The RHC associated variants, Arg151Cys, Arg160Trp and Asp294His, demonstrated agonist-mediated increases in cAMP and phosphorylation of cAMP-responsive element-binding protein (CREB). Whereas the Asp294His variant showed severely impaired functional responses, the Arg151Cys and Arg160Trp variants retained considerable signaling capacity. Melanoma cells homozygous for either the Arg151Cys variant or consensus sequence both elicited CREB phosphorylation in response to alpha-MSH in the presence of IBMX. The common RHC alleles, Arg151Cys, Arg160Trp and Asp294His, are neither complete loss-of-function receptors nor are they functionally equivalent. (c) 2005 Elsevier Inc. All rights reserved.