Crise de hegemonia e emergência de novos atores na Bolívia: o governo de Evo Morales

The presidency of Evo Morales, indigenous leader and who heads the party Movement Towards Socialism (MAS), opens a series of transformations in several dimensions. The changes in socio-economic and political power express the critic of long-term coloniality relations between a dominant white elite and an indigenous subordinate majority that deepens after national independence. Following this perspective, present in sectors of support to the government, the strategy of the MAS cannot follow the tradition of social revolutions that operated structural breaks in the mode of production and the state organization, but points to a new decolonizing revolution, cultural and political, articulating an indigenism of broad nature, flexible and open to popular social movements. This view is facing critics in sectors of the left that identify the renewal of capitalist modernization process initiated in 1952 under the leadership of the Nationalist Revolutionary Movement (MNR), extending citizenship and democratizing access to the state for recognition of Indians as such. From this perspective, the transformations proposed by MAS tend to favor a system restoration by diversifying its economic and social base. From the contrast provided by these two lines of interpretation, we intend to analyze the structural possibilities of the strategy of the government of Evo Morales, taking as historical reference the transformations wrought by the nationalist revolution of 1952 and the neoliberal reforms initiated in 1980.

O Ensaísmo na Historiografia Brasileira

In this paper we analyze the question of character essayistic the historiography of the first half of the twentieth century. We examined this issue due to the emergence of a new trend on the historiographical colonization (School of Rio) who criticizes, among other things, the essay-like character in historiography. Whereas the criticism expressed how a new trend breaks with the existing historiography, we decided to examine this critical gauge. To promote the overcoming of a certain history is necessary to understand it in its historicity, that is, the motivations that led historians to examine the history of a given way. Of course, criticism is a moment of transcendence. But to be a radical departure is necessary to understand the historiography of historical criticism and not simply point their supposed mistakes, shortcomings and failures.

Políticas públicas e vulnerabilidade social: uma reflexão teórica a partir de experiência de estágio

This article provides a theoretical reflection on the relationship between public policies and the social vulnerability of children and adolescents, based on the supervised internship of students of Psychology at UNESP/Campus Assis. The work revealed the need to examine the implications that social vulnerability concepts and public policies have in this area of professional activity. The study indicated the importance of addressing the ways that social vulnerability arises, and suggested possible contributions that psychology could make in the social sphere. The work highlights the need for the future psychologist to deepen his/her knowledge of these issues in order to develop a critical professional attitude that breaks from the approach in which individuals and/or their families are considered responsible for the processes that maintain them at risk.

Impaired protamination and sperm DNA damage in a Nellore bull with high percentages of morphological sperm defects in comparison to normospermic bulls

The routine semen evaluation assessing sperm concentration, motility and morphology, does not identify subtle defects in sperm chromatin architecture. Bulls appear to have stable chromatin, with low levels of DNA fragmentation. However, the nature of fragmentation and its impact on fertility remain unclear and there are no detailed reports characterizing the DNA organization and damage in this species. The intensive genetic selection, the use of artificial insemination and in vitro embryo production associated to the cryopreservation process can contribute to the chromatin damage and highlights the importance of sperm DNA integrity for the success of these technologies. Frozen-thawed semen samples from three ejaculates from a Nellore bull showed high levels of morphological sperm abnormalities (55.8±5.1%), and were selected for complementary tests. Damage of acrosomal (76.9±8.9%) and plasma membranes (75.7±9.3%) as well as sperm DNA strand breaks (13.8±9.5%) and protamination deficiency (3.7±0.6%) were significantly higher compared to the values measured in the semen of five Nellore bulls with normospermia (24.3±3.3%; 24.5±6.1%; 0.6±0.5%; 0.4±0.6% for acrosome, plasma membrane, DNA breaks and protamine deficiency, respectively) (P<0.05). Motility and percentage of spermatozoa with low mitochondrial potential showed no differences between groups. This study shows how routine semen analyses (in this case morphology) may point to the length and complexity of sperm cell damage emphasizing the importance of sperm function testing.

Investigação do papel de HJURP (Holliday Junction Recognizing Protein) na resistência de células de glioblastoma multiforme à radiação ionizante

Pós-graduação em Biociências e Biotecnologia Aplicadas à Farmácia - FCFAR

Formas de vida da mulher brasileira no discurso jurídico

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Evaluation of pH effects on genomic integrity in adipose-derived mesenchymal stem cells using the comet assay

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

A candidate short-term toxicity test using Ampelisca brevicornis to assess sublethal responses to pharmaceuticals bound to marine sediments

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Barriers, rather than refugia, underlie the origin of diversity in toads endemic to the Brazilian Atlantic Forest

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Relationship between head and neck cancer therapy and some genetic endpoints

Head and neck cancer (HNC) is the sixth most common human malignancy worldwide. The main forms of treatment for HNC are surgery, radiotherapy (RT) and chemotherapy (CT). However, the choice of therapy depends on the tumor staging and approaches, which are aimed at organ preservation. Because of systemic RT and CT genotoxicity, one of the important side effects is a secondary cancer that can result from the activity of radiation and antineoplastic drugs on healthy cells. Ionizing radiation can affect the DNA, causing single and double-strand breaks, DNA-protein crosslinks and oxidative damage. The severity of radiotoxicity can be directly associated with the radiation dosimetry and the dose-volume differences. Regarding CT, cisplatin is still the standard protocol for the treatment of squamous cell carcinoma, the most common cancer located in the oral cavity. However, simultaneous treatment with cisplatin, bleomycin and 5-fluorouracil or treatment with paclitaxel and cisplatin are also used. These drugs can interact with the DNA, causing DNA crosslinks, double and single-strand breaks and changes in gene expression. Currently, the late effects of therapy have become a recurring problem, mainly due to the increased survival of HNC patients. Herein, we present an update of the systemic activity of RT and CT for HNC, with a focus on their toxicogenetic and toxicogenomic effects.

Tópicos em teoria das perturbações cosmológicas

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

O design no contexto histórico da arte: uma visão da arte e do design a partir do ornamento

Drawing an equivalence analogy between the subjects of style and the ornamentation, the study leans on Aloïs Riegl's theory in order to sketch an anthropological reflection for the appearance of the design and some of their respective confluences with the art. Enriched by the progresses that the psychology of the visual perception provided to the contemporary understanding for the artistic representation, and consequently of this historicity, breaks of the hypothesis that this appearance has given in a process naturally evolutionary, aiming at to supply an inherent human need.

Les liaisons dangereuses na Tela: ligações 'perigosas' entre cinema e literatura

The purpose of this article is to comment on the film adaptation by director Stephen Frears of the 18th-century novel Les liaisons dangereuses (in English, Dangerous Liaisons) by Choderlos de Laclos. It compares the film composition to the basic formal aspects of the novel. If, on one hand, Frears’ 1988 film adaptation breaks away from Laclos’ epistolary novel for being aligned with the standard elements of the classical cinema, on the other, it reveals a surprising affinity to the literary work: the relation with the theatrical language.

A música no segundo Nietzsche

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Qualidade dos processos mecanizados de semeadura e colheita na cultura da soja

Pós-graduação em Agronomia (Produção Vegetal) - FCAV