NIH Animal Center.

Mode of access: Internet.

The doctor, is career, his business, his human relations.

"Principles of medical ethics of the American Medical Association": p. 136-146.

The place of animals in human thought.

Reprinted in part, from the Contemporary review. cf. Pref.

The dignity of human nature : or, a brief account of the certain and established means for attaining the true end of our existence. In four books.

1. Of prudence.--2. Of knowledge.--3. Of virtue.--4. Of revealed religion.

Motion devices for linear and angular oscillation and for abrupt acceleration studies on human subjects (impact), a description of facilities in use and proposed;

Includes bibliographies.

Supplement to former paper, entitled, Experimental inquiry into the composition of some of the animals fed and slaughtered as human food. Composition of the ash of the entire animals, and of certain separated parts,

From the Philosophical transactions of the Royal Society--Part III, 1883.

The Vulnerable Animals That Therefore We Are : (Non-)Human Animals in D.H. Lawrence's Women in Love

Central to animal studies is the question of words and how they are used in relation to wordless beings such as non-human animals. This issue is addressed by the writer D.H. Lawrence, and the focus of this thesis is the linguistic vulnerability of humans and non-humans in his novel Women in Love, a subject that will be explored with the help of the philosopher Jacques Derrida’s text The Animal That Therefore I Am. The argument is that Women in Love illustrates the human subjection to and constitution in language, which both enables human thinking and restricts the human ability to think without words. This linguistic vulnerability causes a similar vulnerability in non-human animals in two ways. First, humans tend to imagine others, including non-verbal animals, through words, a medium they exist outside of and therefore cannot be defined through. Second, humans are often unperceptive of non-linguistic means of expression and they therefore do not discern what non-human animals may be trying to communicate to them, which often enables humans to justify abuse against non-humans. In addition, the novel shows how this shared but unequal vulnerability can sometimes be dissolved through the likewise shared but equal physical vulnerability of all animals if a human is able to imagine the experiences of a non-human animal through their shared embodiment rather than through human language. Hence the essay shows the importance of recognizing the limitations of language and of being aware of how the symbolizing effect of words influences the human treatment of its others.

Applying for ethics committee approval

Provides information on ethics committee approval. Importance of research ethics committee; Application to the relevant local research ethics committee; Information on obtaining ethical approval.

Blowing the virtue-ethics whistle: Response to Faunce

The author elaborates some issues raised in the theoretical basis of whistleblowing put forward by Faunce. The author considers the relationship between bioethics teaching and professional behaviour and the role of principlism in teaching bioethics and medical ethics.

Ethics and health systems research in 'post'-conflict situations

Although considerable attention has been given to ethical issues related to clinical research in developing countries, in particular related to HIV therapy, there has been limited focus on health systems research, despite its increasing importance in the light of current trends in development assistance. This paper examines ethical issues related to health systems research in 'post'-conflict situations, addressing both generic issues for developing countries and those issues specific to 'post'-conflict societies, citing examples from the author's Cambodian experience. It argues that the destruction of health infrastructure results in a loss of structures and processes that would otherwise protect prospective research subjects who are part of vulnerable populations. It identifies the growth of health systems research as part of a trend towards sectoral and programmatic development assistance, the emergence of 'knowledge generation' as a form of research linked to development, and the potential for conflict where multilateral and bilateral donors are both primary funders and users of health systems research. It also examines the position of the health system researcher in relation to the sponsors of this research, and the health system being analysed.

Genetic screening for susceptibility to depression: can we and should we?

Objective: To summarize current knowledge about genetic susceptibility to mood disorders and examine ethical and policy issues that will need to be addressed if robustly replicated susceptibility alleles lead to proposals to screen and intervene with persons at increased genetic risk of developing mood disorders. Method: Empirical studies and reviews of the genetics of unipolar and bipolar depression were collected via MEDLINE and psycINFO database searches. Results: A number of candidate genes for depression have been identified, each of which increases the risk of mood disorders two- or threefold. None of the associations between these alleles and mood disorders have been consistently reported to date. Conclusions: Screening the population for genetic susceptibility to mood disorders is unlikely to be a practically useful policy (given plausible assumptions). Until there are effective treatments for persons at increased risk, screening is arguably unethical. Screening within affected families to advise on risks of developing depression would entail screening children and adolescents, raising potentially serious ethical issues of consent and stigmatization. Genetic research on depression should continue under appropriate ethical guidelines that protect the interests of research participants.

The policy and ethical implications of genetic research on attention deficit hyperactivity disorder

Objective: To review the policy and ethical implications of recent research on the molecular genetics of attention deficit hyperactivity disorder (ADHD). Method: MEDLINE and psycINFO database searches were used to identify studies on the genetics of ADHD. The implications of replicated candidate genes are discussed. Results: The findings for most genes have been inconsistent but several studies have implicated the genes in the dopaminergic pathway in the aetiology of ADHD. Conclusions: The current evidence on the genetics of ADHD is insufficient to justify genetic screening tests but it will provide important clues as to the aetiology of ADHD. Genetic information on susceptibility to ADHD has the potential to be abused and to stigmatize individuals. Researchers and clinicians need to be mindful of these issues in interpreting and disseminating the results of genetic studies of ADHD.