934 resultados para Alexander, the Great, 356-323 B.C.


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Various lake phases have developed in the upper Great Lakes in response to isostatic adjustment and changes in water supply since the retreat of the Laurentide Ice Sheet. Georgian Bay experienced a lowstand that caused a basin wide unconformity approximately 7,500 years ago that cannot be explained by geological events. Thecamoebians are shelled protozoans abundant in freshwater environments and they are generally more sensitive to changing environmental conditions than the surrounding vegetation. Thecamoebians can be used to reconstruct the paleolimnology. The abundance of thecamoebians belonging to the genus Centropyxis, which are known to tolerate slightly brackish conditions (i.e. high concentrations of ions) records highly evaporative conditions in a closed basin. During the warmer interval (9000 to 700 yBP), the Centropyxis - dominated population diminishes and is replaced by an abundant and diverse Difflugia dominate population. Historical climate records from Tobermory and Midland, Ontario were correlated with the Lake Huron water level curve. The fossil pollen record and comparison with modem analogues allowed a paleo-water budget to be calculated for Georgian Bay. Transfer function analysis of fossil pollen data from Georgian Bay records cold, dry winters similar to modem day Minneapolis, Minnesota. Drier climates around this time are also recorded in bog environments in Southem Ontario - the drying of Lake Tonawanda and inception of paludification in Willoughby Bog, for instance, dates around 7,000 years ago. The dramatic impact of climate change on the water level in Georgian Bay underlines the importance of paleoclimatic research for predicting future environmental change in the Great Lakes.

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The ovariectomized (OVX) rat, a preclinical model for studying postmenopausal bone loss, may also be used to study differences in alveolar bone (AB). The objectives of this study were to quantify the differences in AB following estrogen replacement therapy (ERT), and to investigate the relationship between AB structure and density, and trabecular bone at the femoral neck (FN) and third lumbar vertebral body (LB3). Estrogen treated rats had a higher bone volume fraction (BV/TV) at the AB region (9.8% P < 0.0001), FN (12% P < 0.0001), and LB3 (11.5% P < 0.0001) compared to the OVX group. BV/TV of the AB was positively correlated with the BV/TV at the FN (r = 0.69 P < 0.0001) and the LB3 (r = 0.75 P < 0.0001). The trabecular number (Tb.N), trabecular separation (Tb.Sp), and structure model index (SMI) were also positively correlated (P < 0.05) between the AB and FN (r = 0.42, 0.49, and 0.73, respectfully) and between the AB and LB3 (r = 0.44, 0.63, and 0.69, respectfully). Given the capacity of AB to respond to ERT, future preclinical drug/nutritional intervention studies aimed at improving skeletal health should include the AB as a region of interest (ROI).

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Presentation from the Office of Macdonald and Rykert regarding the Case of O’Connor vs. the Great Western Railway Co. This is a handwritten, 9 ½ page double sided document). Some of the witnesses for the plaintiff included: Robert Johnson, John Ryder, Edward Duffy, Gilbert Gregory, John Cutter, James Patterson, Samuel Rush and Francis Bigger, among others. They claimed that the Great Western Railway Co. was destroying their land. Jacob Dittrick claimed that the culverts were not large enough to carry off water. Mr. Jackson noticed injury to his flats. Wild grass was destroying the bottom grass, May 6, 1836.

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Approximate estimate of the cost of extending the Port Dalhousie and Thorold Railway from Geneva Street to the Great Western Railway Station at Lock no. 12 (2 copies) [one appears to be a rough copy] (2 pages, handwritten), Feb. 2, 1855.

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Mr. Woodward’s timetable regarding the suspension bridge to Toronto via the Great Western Railway and Port Dalhousie Railway (1 page, handwritten), Jan. 22, 1856

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Iron Mountain Route Railway schedule: the great through line St. Louis, Arkansas and Texas to the Hot Springs of Arkansas.

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Letter and envelope addressed to S.D. Woodruff from the office of T.B. Stewart and Co. of New York, Manufacturers of Mantles, Marble and Wood Mantels. The letter states that the heater and grates have been shipped, July 14, 1876.

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Post card with a notice of freight arrival addressed to S.D. Woodruff from the Great Western Railway for castings, a keg and grates, Aug.11, [1876].

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Indenture of agreement between the Great Western Railway Company and the Erie and Ontario Railway Company in order for the companies to unite, March 20, 1854.

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UANL