Anatomical features of the urethra and urinary bladder catheterization in female mice and rats. An essential translational tool

PURPOSE: To present fundamental anatomical aspects and technical skills necessary to urethra and urinary bladder catheterization in female mice and rats. METHODS: Urethral and bladder catheterization has been widely utilized for carcinogenesis and cancer research and still remains very useful in several applications: from toxicological purposes as well as inflammatory and infectious conditions to functional aspects as bladder dynamics and vesicoureteral reflux, among many others. RESULTS: Animal models are in the center of translational research and those involving rodents are the most important nowadays due to several advantages including human reproducibility, easy handling and low cost. CONCLUSIONS: Although technical and anatomical pearls for rodent urethral and bladder access are presented as tackles to the advancement of lower urinary tract preclinical investigation in a broaden sight, restriction to female animals hampers the male microenvironment, demanding future advances.

Ipsis video litteris: processos e procedimentos artísticos da escrita na televisão - videografia

Pós-graduação em Artes - IA

Gestão escolar democrática: registros em vídeo ferramenta auxiliar à prática reflexiva

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Contribuições da educação permanente para avaliação docente da prática profissional do estudante de medicina

Pós-graduação em Educação - FFC

Alkylation of Histidine Residues of Bothrops jararacussu Venom Proteins and Isolated Phospholipases A(2): A Biotechnological Tool to Improve the Production of Antibodies

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Quantificação da desintegração de comprimidos por fluxo ótico em seqüências de imagens de biosusceptometria AC

AC Biosusceptometry (ACB) is a low-cost biomagnetic tool that has been successfully applied on pharmaceutical research to evaluate performance of solid dosage forms. The aim of this work was to evaluate the Horn & Shunck method to access tablet disintegration. To evaluate the HS results was record on video a test with a objet moving in a rail with a constant velocity. The desintegration was recorded on video and ACB, which used have seven pairs of detection coils and a pair of excitation coils to mensure the magnetic ux variation. The signals were ampli ed and digitalized to create images, which were restored by Wiener lter, while the video images are converted to gray scale, both are normalized and binarized and had the optical ow estimation calculated by Horn & Schunck (HS) algorithm. All signals and images are processed and developed algorithm on Matlab. During the tests the ve tablets (500mg ferrite, 375mg excipients, compression 10 to 50 kN) were on a becker between of the ACB system and of the video system, and only touching the surface of the water. With all OF maps calculated was realized the sum of the resultants of each, to get a disintegration process resultant for each compression. Whit that was possible observed the disintegration behaves. For the compression force study the HS components of each sequence was sum, take mean and normalized for sequence's max modulo, therefore can be observed a high growing on less compression tablets. We can conclude the HS algorithm is viable to tablets disintegration data collection and whit that was possible to create a tablets disintegration analyzes protocol, which would be useful on desintegration kinetics study

Video mapping: um estudo teórico e prático sobre projeção mapeada

The project presents an explanation of the technique of video mapping, resource use, origin and use of the strands. Also conducts multidisciplinary literature review of concepts that can be applied to the technique of video mapping: Augmented Reality, Spatiality in Virtual and Real Environments. The project also introduces aspects of the history of cinema and audiovisual narrative. In addition conducts an inventory of software and hardware required for the technique of video mapping, reports performing experiments with the use of the technique and discusses the results obtained. As a contribution to development area, proposes to use video mapping as an augmented reality tool at an immersive experimental film language

O desenvolvimento de habilidades argumentativas no ensino médio: perspectiva a partir de um minicurso investigativo com base na história da ciência

The performance of investigative activities with lessons in teaching Science and Chemistry has promoted meaningful learning of scientific knowledge. This study aimed to develop the links between higher education for research and skills argumentative, aimed at building the scientific concept on combustion of the candle in a closed container, for students from two classes of 3rd year of high school, two city schools Bauru, São Paulo. We decided to do a short course investigative, to respond argumentative skills which are developed during the minicourse using investigative activities, knowledge from the history and philosophy of science. The results were gathered from analysis of video recordings of episodes of the short course in both the groups, to produce a higher rate of use of argumentative skill, which were classified into categories according to the prior knowledge of the subject, 'factual knowledge' , 'understanding of concepts' and 'reasoning and analysis.' From the information obtained, it was found that both the teachers and the students were consistent in their actions, and that the activity of reasoning is key to learning. Thus, one can realize that knowledge is not acquired all at the same time, each individual depends on the mediation of the teacher in order to reach different design more appropriate teaching and investigative linked with the argument can be the key tool to acquire this knowledge

ITScan: a web-based analysis tool for Internal Transcribed Spacer (ITS) sequences

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Tecnologias Digitais da Informação e Comunicação: explorando as possibilidades pedagógicas da produção de vídeos

Pós-graduação em Docência para a Educação Básica - FC

Antitubercular drug discovery: the molecular modification as promise tool

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

A graphical tool for the tomographic characterisation of microstructural features on metal matrix composites

Research on the micro-structural characterization of metal-matrix composites uses X-ray computed tomography to collect information about the interior features of the samples, in order to elucidate their exhibited properties. The tomographic raw data needs several steps of computational processing in order to eliminate noise and interference. Our experience with a program (Tritom) that handles these questions has shown that in some cases the processing steps take a very long time and that it is not easy for a Materials Science specialist to interact with Tritom in order to define the most adequate parameter values and the proper sequence of the available processing steps. For easing the use of Tritom, a system was built which addresses the aspects described before and that is based on the OpenDX visualization system. OpenDX visualization facilities constitute a great benefit to Tritom. The visual programming environment of OpenDX allows an easy definition of a sequence of processing steps thus fulfilling the requirement of an easy use by non-specialists on Computer Science. Also the possibility of incorporating external modules in a visual OpenDX program allows the researchers to tackle the aspect of reducing the long execution time of some processing steps. The longer processing steps of Tritom have been parallelized in two different types of hardware architectures (message-passing and shared-memory); the corresponding parallel programs can be easily incorporated in a sequence of processing steps defined in an OpenDX program. The benefits of our system are illustrated through an example where the tool is applied in the study of the sensitivity to crushing – and the implications thereof – of the reinforcements used in a functionally graded syntactic metallic foam.

Subtitling as a pedagogical tool for language teaching in journalism

This study was designed to present and discuss some results produced by a research involving the use of English subtitles of some news videos from the webiste Reuters.com (http://www.reuters.com) with pedagogical reasons in a Brazilian context (Academic English for Journalism). We have developed the research during two semesters at UNESP (Universidade Estadual Paulista Júlio de Mesquita Filho). The professor in charge of the study has chosen the students of Journalism as the audience to whom the videos were presented. The assumptions of many theorists and experts in Audiovisual Translation were adopted as our Theoretical Sources. The first step of the study was the assessment of the syllabus of each course. This was very helpful as a guidance in order to choose the most relevant and interesting videos for students. After the evaluation of academic and professional interests, we chose some videos to insert appropriate subtitles, according to some strategies suggested by Panayota Georgakopoulou and Henrik Gottlieb. Finally we presented the videos during the English classes. At the first time, they were presented without subtitles just to notice the comprehension level of the students. After that, the videos were presented with English subtitles. As we first assumed, the students haven’t had the whole comprehension of specific details during the first presentation, they have just used their previous knowledge and the visual aids to help them in a superficial understanding of the news. As the subtitles appear, the process of communication was finally accomplished.

The interactive whiteboard in primary school: a case study of a brazilian district school

Interactive whiteboards (IWB) consist of a set of technological equipment organized in order to fulfill a specific task, enabling the development of didactic activities. Because they are associated to computers’ potentiality, interactive whiteboards can provide bigger interactivity between: teacher and students, students and content, and among students. This work’s main objective is to present some of the results yielded from a research related to the way students perceive interactive whiteboards in the classroom. In order to analyze the IWB usage dynamics, some educational applications in the field of mathematics were applied in the 3rd grade of elementary school. Aside from observation, video recordings were made and students were interviewed about the interactive whiteboard, in order to understand how these students observe and engage with the technological tool. IWB do not transform classroom’s reality by themselves, however, their physical presence and usage amount to external reinforcement can change student’s behavior positively.

Improving business innovation and research through the application of neuromarketing with ethics: a framework

The objective of this paper is to analyse and to discuss the ethical issues in the field of research known as neuromarketing, a tool used to improve innovation in companies. It uses techniques available to neuroscientists, both newer and more sophisticated ones along with traditional ones, but now for new purposes. From the beginning, this new area has evoked discussions about ethical aspects related to the results presented. Despite the unrestricted controversy surrounding the theme, few studies have discussed ethical issues involved in this line of research in a pragmatic manner. In this sense, this paper seeks to analyse and discuss ethical issues in neuromarketing research through a literature review and the proposal for a framework of ethical mapping. This framework revealed the ethical implications that would be most prominent in certain research situations: the purpose of utilising neuromarketing techniques, organisational type, and industrial sector, among others.