Nível de atividade física e imagem corporal de alunos ingressos de um curso de educação física da Cidade de Santo André - SP

The aim of this study was to evaluate the level of physical activity confronting to the real and ideal body image of 65 individuals of both gender (27 women and 38 men) aged between 18 and 37 years old, all students of a Physical Education College of Santo André´s City - SP. The instruments used were the International Physical Activity Questionnaire, Short version (IPAQ, 2005) and Test for assessment of Body Image proposed by Stunkard et al., (1983) and adapted by Marsh and Roche (1996). According to the results, male subjects are more actives compared with female, as well as for the real and ideal body image males showed no significant difference, however, the females showed differences between the real and the ideal body image, between the gender no significant differences existed on the real and ideal body image. We can conclude that the students of this Physical Education College mostly presents in moderate or high level of physical activity, showing that the male are pleased with the real and ideal body image, and for a willing female body silhouette thinner ideal than real, with no significant differences between genders, and thus leading us to believe that the physical education College lead the students to experience practical activities becoming them lifestyle most active in search of a better quality of life and wellness.

Prática de atividade física em estudantes das áreas de saúde e não saúde de uma universidade do interior de São Paulo

The world’s population is having more and more difficulties in performing their daily activities and leisure, becoming, this way, more sedentary. Sedentary lifestyle can be considered as a reduction or as a lack of physical activity, less than the minimum volume suggested by the World Health Organization (WHO). Physical activity changes the behavior and some environmental acts. This study aimed to identify the NAF of students in the area of Physical Education and Healt Nursing and compare it with identified students’ levels non-health areas, being Production Engineer and Pedagogy. Aimed to correlate the found volume of 15 participants, with the state of cardio respiratory fitness (VO2max). The study included 125 students of both sexes from a university located in São Paulo state country. We conducted a cross-sectional study from August to October of 2012. For the initial test of the volume of physical activity we used the International Physical Activity Questionnaire (IPAQ) long version. In order of assessing cardio respiratory fitness, the Katch and McArdle seat test (1981) was used. Data were analyzed according to Physical Activity Level (PAL) presented by the university students in sessions 1, 2, 3, 4 of the IPAQ, and 15 students’ results were correlated with VO2max test. From these results we can say that: IPAQ session 1 showed that students in the health area are statistically superior to the non-health students area to the high-active classification. In session 2 the results were significant and superior to the health area and very active in sedentary classification. The session 3 results were very similar to session 1, showing that the health area as high-active with statistics differences. In session 4 we can see very significant results for health area in high-active areas and irregular actives. A total of 4 sessions found significant results for very active and sedentary. When was the attempt of association between levels 15 participants found the IPAQ long version and test bank VO2max, the results showed no significant association. The results of this study show a need for policies to encourage physical activity in the University environment, emphasizing a greater need for students who do not work in healthcare.

Bioprospecção de fungos endofílicos Camarops sp., Periconia atropurpurea e Pseudofusicoccum stromaticum e avaliação epigenética de Phoma sp

Pós-graduação em Química - IQ

Estudo da relação de ordem-desordem estrutural em nanopartículas de TiO2

Pós-graduação em Química - IQ

Escolas do campo e atendimento educacional especializado em sala de recursos multifuncional

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A construção da carreira docente e a identidade do professor

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Plano Municipal de Educação de Rio Claro - SP: desafios e perspectivas na garantia do direito à educação

Pós-graduação em Educação - IBRC

Department of Veterinary and Biomedical Sciences: 2000 Annual Report

Foreword, 2000 John A . Schmitz. Professor and Department Head Veterinary and Biomedical Sciences Personnel Faculty Profiles Teaching program Research program Extension Program Nebraska Veterinary and Diagnostic Laboratory Systems Grants and Contracts Funded or Active in 2000 Patents by VBMS Faculty in 2000 Publications by VBMS Faculty in 2000 Presentations by VBMS Faculty in 2000 Articles Regarding the Department in 2000 Selected Committees, Editorial and Other Appointments of VBMS Faculty Departmental Budget Summaries Nebraska Agricultural Statistics 1999

Plano Municipal de Educação de Rio Claro - SP: desafios e perspectivas na garantia do direito à educação

Pós-graduação em Educação - IBRC

A idéia de jogo em obras de John Cage e no ambiente da livre improvisação

Este texto examina as principais diferenças de enfoque relacionadas ao papel dos intérpretes na realização de duas diferentes propostas de jogo. Para tanto, são comparadas algumas obras de John Cage e as práticas de grupos que se dedicam à livre improvisação musical, principalmente do grupo Akronon.1 Procura-se demonstrar que as propostas de Cage, que estão situadas num plano conceitual, e as propostas da livre improvisação, que partem de uma prática experimental interativa baseada numa manipulação empírica dos sons, resultam em concepções bastante distintas a respeito do papel do intérprete. A partir desta perspectiva, afirma-se o caráter potente da livre improvisação que pode ser pensada enquanto prática de um jogo ideal conforme conceituação proposta pelo filósofo francês Gilles Deleuze

Characterization of a Toxoneuron nigriceps (Viereck) (Hymenoptera: Braconidae) - derived chitinase and its potential for pest control

The larval endoparasitoid Toxoneuron nigriceps (Viereck) (Hymenoptera: Braconidae) has a toolbox of biological weapons to secure for host colonization and the successful parasitization of its host Heliothis virescens (F.) (Lepidoptera: Noctuidae). The cDNA of a putative chitinase has been previously isolated and initially characterized from teratocytes of this parasitoid among the plethora of molecules available in the venom and calyx fluids injected by females, oral and/or anal secretions released by the parasitoid larvae and/or produced by the expression of genes of the symbiotic associated polydnavirus. This putative chitinase has been initially associated with the host cuticle digestion to allow for parasitoid egression and with the asepsis of the host environment, acting as an antimicrobial. As chitinases are commonly expressed in plants against plant pathogens, the chitinase derived from the teratocytes of T. nigriceps is a potential tool for the development of insect pest control methods based on the disruption of the perithrophic membrane of herbivores. Therefore, we aimed to characterize the activity of the putative chitinase from teratocytes of T. nigriceps (Tnchi) produced using the Escherichia coli expression system and its potential to control H. virescens larvae when expressed into transgenic tobacco plants. The purified E. coli-produced Tnchi protein showed no chitinolitic activity, but was active in binding with colloidal and crystalline chitins in water and with colloidal chitin in buffered solution (pH = 6.74). Transgenic tobacco plants showed no enhanced chitinolitic activity relative to control plants, but survival of three-day old larvae of H. virescens was severely affected when directly fed on transgenic tobacco leaves expressing the recombinant Tnchi protein. Some properties of the Tnchi protein and the potential use of Tnchi-transgenic plants to control plant pests are discussed. (c) 2012 Elsevier Inc. All rights reserved.

Aspergillus fumigatus mitochondrial electron transport chain mediates oxidative stress homeostasis, hypoxia responses and fungal pathogenesis

We previously observed that hypoxia is an important component of host microenvironments during pulmonary fungal infections. However, mechanisms of fungal growth in these in vivo hypoxic conditions are poorly understood. Here, we report that mitochondrial respiration is active in hypoxia (1% oxygen) and critical for fungal pathogenesis. We generated Aspergillus fumigatus alternative oxidase (aoxA) and cytochrome C (cycA) null mutants and assessed their ability to tolerate hypoxia, macrophage killing and virulence. In contrast to ?aoxA, ?cycA was found to be significantly impaired in conidia germination, growth in normoxia and hypoxia, and displayed attenuated virulence. Intriguingly, loss of cycA results in increased levels of AoxA activity, which results in increased resistance to oxidative stress, macrophage killing and long-term persistence in murine lungs. Thus, our results demonstrate a previously unidentified role for fungal mitochondrial respiration in the pathogenesis of aspergillosis, and lay the foundation for future research into its role in hypoxia signalling and adaptation.

Docking, synthesis and pharmacological activity of novel urea-derivatives designed as p38 MAPK inhibitors

p38 mitogen-activated protein kinase (p38 MAPK) is an important signal transducing enzyme involved in many cellular regulations, including signaling pathways, pain and inflammation. Several p38 MAPK inhibitors have been developed as drug candidates to treatment of autoimmune disorders, such as rheumatoid arthritis. In this paper we reported the docking, synthesis and pharmacological activity of novel urea-derivatives (4a-e) designed as p38 MAPK inhibitors. These derivatives presented good theoretical affinity to the target p38 MAPK, standing out compound 4e (LASSBio-998), which showed a better score value compared to the prototype GK-00687. This compound was able to reduce in vitro TNF-alpha production and was orally active in a hypernociceptive murine model sensible to p38 MAPK inhibitors. Otherwise, compound 4e presented a dose-dependent analgesic effect in a model of antigen (mBSA)-induced arthritis and anti-inflammatory profile in carrageenan induced paw edema, indicating its potential as a new antiarthritis prototype. (c) 2012 Elsevier Masson SAS. All rights reserved.

Functional characterization and oligomerization of a recombinant xyloglucan-specific endo-beta-1,4-glucanase (GH12) from Aspergillus niveus

Xyloglucan is a major structural polysaccharide of the primary (growing) cell wall of higher plants. It consists of a cellulosic backbone (beta-1,4-linked glucosyl residues) that is frequently substituted with side chains. This report describes Aspergillus nidulans strain A773 recombinant secretion of a dimeric xyloglucan-specific endo-beta-1,4-glucanohydrolase (XegA) cloned from Aspergillus niveus. The ORF of the A. niveus xegA gene is comprised of 714 nucleotides, and encodes a 238 amino acid protein with a calculated molecular weight of 23.5 kDa and isoelectric point of 4.38. The optimal pH and temperature were 6.0 and 60 degrees C, respectively. XegA generated a xyloglucan-oligosaccharides (XGOs) pattern similar to that observed for cellulases from family GH12, i.e., demonstrating that its mode of action includes hydrolysis of the glycosidic linkages between glucosyl residues that are not branched with xylose. In contrast to commercial lichenase, mixed linkage beta-glucan (lichenan) was not digested by XegA, indicating that the enzyme did not cleave glucan beta-1,3 or beta-1,6 bonds. The far-UV CD spectrum of the purified enzyme indicated a protein rich in beta-sheet structures as expected for GH12 xyloglucanases. Thermal unfolding studies displayed two transitions with mid-point temperatures of 51.3 degrees C and 81.3 degrees C respectively, and dynamic light scattering studies indicated that the first transition involves a change in oligomeric state from a dimeric to a monomeric form. Since the enzyme is a predominantly a monomer at 60 degrees C. the enzymatic assays demonstrated that XegA is more active in its monomeric state. (c) 2012 Elsevier B.V. All rights reserved.

Promoter regions of Plasmodium vivax are poorly or not recognized by Plasmodium falciparum

Abstract Background Heterologous promoter analysis in Plasmodium has revealed the existence of conserved cis regulatory elements as promoters from different species can drive expression of reporter genes in heterologous transfection assays. Here, the functional characterization of different Plasmodium vivax promoters in Plasmodium falciparum using luciferase as the reporter gene is presented. Methods Luciferase reporter plasmids harboring the upstream regions of the msp1, dhfr, and vir3 genes as well as the full-length intergenic regions of the vir23/24 and ef-1α genes of P. vivax were constructed and transiently transfected in P. falciparum. Results Only the constructs with the full-length intergenic regions of the vir23/24 and ef-1α genes were recognized by the P. falciparum transcription machinery albeit to values approximately two orders of magnitude lower than those reported by luc plasmids harbouring promoter regions from P. falciparum and Plasmodium berghei. A bioinformatics approach allowed the identification of a motif (GCATAT) in the ef-1α intergenic region that is conserved in five Plasmodium species but is degenerate (GCANAN) in P. vivax. Mutations of this motif in the P. berghei ef-1α promoter region decreased reporter expression indicating it is active in gene expression in Plasmodium. Conclusion Together, this data indicates that promoter regions of P. vivax are poorly or not recognized by the P. falciparum transcription machinery suggesting the existence of P. vivax-specific transcription regulatory elements.