Estudo das alterações eletrocorticográficas na insuficiência hepática aguda experimental.

The aim of this study was to test the application and value of electrocorticography (ECG) in the early diagnosis and characterization of electrocorticograms changes on experimental fulminant hepatic failure (FHF). Our material was composed of two groups of guinea pigs: a) ethanolamine group--42 animals with FHF induced by intrabiliary injection of 2.5 ml of monoethanolamine oleate; b) control group--10 animals submitted to intrabiliary injection of 2.5 ml of saline. Electrocorticograms recordings were taken in both groups with the electrodes implanted on the parieto-occipital regions of the skull. The hepatic failure was characterized by clinical manifestations, serum biochemical tests and histopathological findings. In the early hepatic coma the electrocorticograms could not be unequivocally distinguished from normal pattern, and alpha rhythm was recognizable in most animals. With further deterioration of the clinical condition the tracing showed progressive slowness of the normal rhythm, increased voltage and triphasic waves followed by suppression of electrical activity preceding the animal death. The electrocorticography was not suitable for the early diagnosis of hepatic coma, since the ECG alterations became evident only in overt coma. However the method could be useful for the characterization of cerebral disorders and the study of the pathogenesis of fulminant hepatic failure.

Immunocytochemical study of Ki-67 as a prognostic marker in canine mammary neoplasia

Background: Canine mammary tumors are challenging for clinicians and pathologists because of complex histologic classification, low specificity of cytologic diagnosis, and unpredictable biological behavior. In histologic specimens, expression of tumor proliferation marker Ki-67, a nuclear nonhistone protein, has been shown to have prognostic value for canine mammary tumors and to correlate with malignancy and low survival rates. Objective: The objective of this study was to measure the proliferation index of canine mammary tumors by immunochemical detection of Ki-67 in cytologic specimens and to determine its relationship to clinical and pathologic variables and patient outcome. Methods: Spontaneous mammary tumors from 31 female dogs were surgically excised. Imprint specimens for cytologic evaluation were wet-fixed in ethanol; histologic specimens were prepared routinely. Immunostaining was performed with the PH 177 monoclonal antibody against Ki-67; proliferation index was graded from negative to +++. Dogs were followed for 18 months. Multivariate logistic regression analysis was used to determine correlations between immunocytochemical results, tumor and clinical variables, and patient outcome. Results: Ki-67 proliferation indices in cytologic specimens were significantly lower for nonmalignant tumors than for malignant tumors. High index values of Ki-67 were positively correlated with metastasis, death from neoplasia, low disease-free survival rates, and low overall survival rate. With the exception of 4 specimens for which cellularity was insufficient, positive expression of Ki-67 in cytologic specimens correlated with that of histologic specimens. Conclusions: The prognostic value of the Ki-67 index in canine mammary tumors by using wet-fixed cytology imprint specimens was similar to that observed previously for histologic specimens. Immunocytochemical detection of Ki-67 could improve the accuracy and value of cytology by providing safe and rapid information about malignancy and patient outcome. © 2004 American Society for Veterinary Clinical Pathology.

Crônica política sobre um documento contra a ditabranda

This short article, a political chronicle, examines the meanings and political and ideological effects of a Internet petition that was created in February of 2009. Repúdio e Solidariedade (Repudiation and Solidarity) questioned the use of the term ditabranda [a conjunction of two terms, ditadura and branda - or soft dictatorship] disseminated by the São Paulo news daily Folha de S. Paulo to refer to the Brazilian military dictatorship, and manifested solidarity with two University of São Paulo (USP) professors and intellectuals known for their action in defense of human rights in Brazil. Obtaining over eight thousand signatures in a period of less than six weeks, the petition may be considered (as the extensive comments which it includes testify to) a relevant document in the struggle for the right to truth and justice regarding what really happened during the period of the Brazilian military regime (1964-1985). Perhaps its most relevant symbolic role is that of staking claims within an ideological struggle over the memory of 1964. In the center of these claims sits a banner with the old motto No pasarán. In other words, democratic and progressive sectors of Brazilian society that supported Repúdio e Solidariedade made it clear that they were not going to quietly accept falsified views of history that are an insult to the memory of those who struggled, were tortured and died in the struggle to redemocratize the country.

Bond markets for Latin American debt in the 1990s

Includes bibliography

Utilização de fermento de descarte de cervejaria na produção de aguardente de Licor de laranja

Pós-graduação em Alimentos e Nutrição - FCFAR

Avaliações clínicas e laboratoriais da intoxicação experimental por veneno de sapo em cães

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Intoxicação experimental por veneno de sapo em cães anestesiados: estudo clínico e laboratorial

Pós-graduação em Medicina Veterinária - FMVZ

Webjornalismo infantil: por uma interação informativa

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Corpo-mídia ou corpo-suporte?: representações do signo corpo em publicidades de perfumes

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Docweb: análise do documentário on-line HayMotivo.com

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Intencionalidade e indeterminação interpretativa no design de produto

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

O erro em sala de aula: subsídios para o ensino do eletromagnetismo

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Arte e ética em The Bell de Iris Murdoch

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Uma análise do embeddedness na formação de valor em redes de empresas: um exemplo de aplicação em uma rede do setor metal-mecânico

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Um roteiro para aquisição, criação e armazenamento do conhecimento: uma pesquisa-ação em uma organização do setor da construção civil

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)