998 resultados para STARS: INDIVIDUAL: GAMMA CASSIOPEIAE
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Iowa School District Surtax Report 2003
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Iowa School District Surtax Report 2004
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Iowa School District Surtax Report 2005
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Iowa Individual Income Tax Statistical Report 1997
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Iowa Individual Income Tax Statistical Report 1998
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Iowa Individual Income Tax Statistical Report 1999
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Iowa Individual Income Tax Statistical Report 2000
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Iowa Individual Income Tax Statistical Report 2001
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Iowa Individual Income Tax Statistical Report 2002
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Iowa Individual Income Tax Statistical Report 2003
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Iowa Individual Income Tax Statistical Report 2004
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Iowa Individual Income Tax Statistical Report 2005
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γ-Hydroxybutyric acid (GHB) is an endogenous short-chain fatty acid popular as a recreational drug due to sedative and euphoric effects, but also often implicated in drug-facilitated sexual assaults owing to disinhibition and amnesic properties. Whilst discrimination between endogenous and exogenous GHB as required in intoxication cases may be achieved by the determination of the carbon isotope content, such information has not yet been exploited to answer source inference questions of forensic investigation and intelligence interests. However, potential isotopic fractionation effects occurring through the whole metabolism of GHB may be a major concern in this regard. Thus, urine specimens from six healthy male volunteers who ingested prescription GHB sodium salt, marketed as Xyrem(®), were analysed by means of gas chromatography/combustion/isotope ratio mass spectrometry to assess this particular topic. A very narrow range of δ(13)C values, spreading from -24.810/00 to -25.060/00, was observed, whilst mean δ(13)C value of Xyrem(®) corresponded to -24.990/00. Since urine samples and prescription drug could not be distinguished by means of statistical analysis, carbon isotopic effects and subsequent influence on δ(13)C values through GHB metabolism as a whole could be ruled out. Thus, a link between GHB as a raw matrix and found in a biological fluid may be established, bringing relevant information regarding source inference evaluation. Therefore, this study supports a diversified scope of exploitation for stable isotopes characterized in biological matrices from investigations on intoxication cases to drug intelligence programmes.
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Guide manual for using the Human Resource Information System for the state of Iowa.
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Guide manual for using the Human Resource Information System for the state of Iowa.