Endoscopic optical coherence tomography : design and application

This thesis presents an investigation on endoscopic optical coherence tomography (OCT). As a noninvasive imaging modality, OCT emerges as an increasingly important diagnostic tool for many clinical applications. Despite of many of its merits, such as high resolution and depth resolvability, a major limitation is the relatively shallow penetration depth in tissue (about 2∼3 mm). This is mainly due to tissue scattering and absorption. To overcome this limitation, people have been developing many different endoscopic OCT systems. By utilizing a minimally invasive endoscope, the OCT probing beam can be brought to the close vicinity of the tissue of interest and bypass the scattering of intervening tissues so that it can collect the reflected light signal from desired depth and provide a clear image representing the physiological structure of the region, which can not be disclosed by traditional OCT. In this thesis, three endoscope designs have been studied. While they rely on vastly different principles, they all converge to solve this long-standing problem.

A hand-held endoscope with manual scanning is first explored. When a user is holding a hand- held endoscope to examine samples, the movement of the device provides a natural scanning. We proposed and implemented an optical tracking system to estimate and record the trajectory of the device. By registering the OCT axial scan with the spatial information obtained from the tracking system, one can use this system to simply ‘paint’ a desired volume and get any arbitrary scanning pattern by manually waving the endoscope over the region of interest. The accuracy of the tracking system was measured to be about 10 microns, which is comparable to the lateral resolution of most OCT system. Targeted phantom sample and biological samples were manually scanned and the reconstructed images verified the method.

Next, we investigated a mechanical way to steer the beam in an OCT endoscope, which is termed as Paired-angle-rotation scanning (PARS). This concept was proposed by my colleague and we further developed this technology by enhancing the longevity of the device, reducing the diameter of the probe, and shrinking down the form factor of the hand-piece. Several families of probes have been designed and fabricated with various optical performances. They have been applied to different applications, including the collector channel examination for glaucoma stent implantation, and vitreous remnant detection during live animal vitrectomy.

Lastly a novel non-moving scanning method has been devised. This approach is based on the EO effect of a KTN crystal. With Ohmic contact of the electrodes, the KTN crystal can exhibit a special mode of EO effect, termed as space-charge-controlled electro-optic effect, where the carrier electron will be injected into the material via the Ohmic contact. By applying a high voltage across the material, a linear phase profile can be built under this mode, which in turn deflects the light beam passing through. We constructed a relay telescope to adapt the KTN deflector into a bench top OCT scanning system. One of major technical challenges for this system is the strong chromatic dispersion of KTN crystal within the wavelength band of OCT system. We investigated its impact on the acquired OCT images and proposed a new approach to estimate and compensate the actual dispersion. Comparing with traditional methods, the new method is more computational efficient and accurate. Some biological samples were scanned by this KTN based system. The acquired images justified the feasibility of the usage of this system into a endoscopy setting. My research above all aims to provide solutions to implement an OCT endoscope. As technology evolves from manual, to mechanical, and to electrical approaches, different solutions are presented. Since all have their own advantages and disadvantages, one has to determine the actual requirements and select the best fit for a specific application.

Iraupen luzeko irakasleriaren garapenaren inpaktu-mailak: kontzepzioetan, hezkuntza hurbilketan eta kultura instituzionalean

[EUS]Unibertsitateko irakasleriaren garapenaren(IG) kontzeptu konprentsibotik abiatuta, doktorego tesi honek iraupen luzeko IG programen inpaktua du aztergai, bai maila indibidualean (kontzepzio eta hurbilketan) eta baita maila organizazional zein instituzionalean ere. Azterketa hau burutzeko metodologia aktiboen (arazoetan, proiektuetan eta kasuetan oinarritutako ikaskuntza) ERAGIN programaren lehendabiziko promozioa hartuko da kasu gisa. Iraupen luzeko estrategiaren (350 ordu) bidez eta ko-mentoria taldeen funtzionamenduan oinarrituz, ikerlan enpirikoak IG-ak irakasleriaren ikas-irakaskuntza kontzepzioetan eta hurbilketan izandako inpaktuaz ageriko ebidentziak ematen ditu, baina baita ikas-irakaskuntzaren inguruan ikertzeko (scholarship of teaching and learning) eta irakaskuntza eremuetan liderra izateko gaitasunaz ere. Honako alderdiok aldaketa organizazionalean murgiltzen gaituzte eta curriculum hibridoaren pausokako gauzapenaren alde lan egiten dute.

Desenvolvimento de um sistema misto de pasta à base de geopolímero e cimento portland para correção de perda de circulação

The materials engineering includes processes and products involving several areas of engineering, allowing them to prepare materials that fulfill the needs of various new products. In this case, this work aims to study a system composed of cement paste and geopolymers, which can contribute to solving an engineering problem that directly involves the exploitation of oil wells subject to loss of circulation. To correct it, has been already proposed the use of granular materials, fibers, reducing the drilling fluid or cement paste density and even surface and downhole mixed systems. In this work, we proposed the development of a slurry mixed system, the first was a cement-based slurry and the second a geopolymer-based slurry. The cement-based slurry was formulated with low density and extenders, 12.0 ppg (1.438 g/cm ³), showing great thixotropic characteristics. It was added nano silica at concentrations of 0.5, 1.0 and 1.5 gps (66.88, 133.76 and 200.64 L/m3) and CaCl2 at concentrations of 0.5, 1, 0 and 1.5%. The second system is a geopolymer-based paste formulated from molar ratios of 3.5 (nSiO2/nAl2O3), 0.27 (nK2O/nSiO2), 1.07 (nK2O/nAl2O3) and 13.99 (nH2O/nK2O). Finally, we performed a mixture of these two systems, for their application for correction of circulation lost. To characterize the raw materials, XRD, XRF, FTIR analysis and titration were performed. The both systems were characterized in tests based on API RP10B. Compressive strength tests were conducted after curing for 24 hours, 7 and 28 days at 58 °C on the cement-based system and the geopolymer-based system. From the mixtures have been performed mixability tests and micro structural characterizations (XRD, SEM and TG). The results showed that the nano silica, when combined with CaCl2 modified the rheological properties of the cement slurry and from the concentration of 1.5 gpc (200.64 L / m³) it was possible to obtain stable systems. The system mixture caused a change in the microstructure of the material by favoring the rate of geopolymer formation to hinder the C3S phase hydration, thus, the production of CSH phases and Portlandite were harmed. Through the mixability tests it can be concluded that the system, due to reduced setting time of the mixture, can be applied to plug lost circulation zones when mixed downhole

Os Fragmentos 19 e 20 dos Systementwürfe 1803/1804, de G.W.F. Hegel : introdução e tradução

O objetivo deste trabalho é traduzir e apresentar os fragmentos 19 e 20 dos Esboços de Sistema de Jena, escritos por Hegel entre 1803 e 1804. Primeiramente, farei uma rápida consideração do significado filosófico desses fragmentos, os quais tratam, desde a peculiar concepção hegeliana da consciência como espírito, da razão teórica e da razão prática como equivalentes, respectivamente, à linguagem e ao trabalho. Procuro sublinhar essa relevância filosófica a partir da interpretação habermasiana dos fragmentos, a qual lhes conferiu notoriedade como tentativa de reconstrução do materialismo histórico. A partir desta breve contextualização, apresenta-se, a seguir, uma tradução para o português dos mencionados fragmentos. _________________________________________________________________________________ ABSTRACT

Relatório de estágio de intervenção comunitária

O Mestrado em Enfermagem, com Especialização em Enfermagem Comunitária, visa a aquisição e desenvolvimento de competências para o exercício autónomo, auto refletido e com poder de avaliação critica sobre os cuidados prestados e a sua qualidade no que diz respeito aos vários níveis de prevenção do cliente comunidade. O presente relatório, realizado no âmbito da unidade curricular de Estágio, pretende descrever, analisar e refletir sobre o percurso da construção de competências específicas para a intervenção especializada em Enfermagem Comunitária e de Saúde Pública. Ele propõe-se sintetizar as etapas de crescimento pessoal e profissional que permitem uma melhoria da qualidade dos cuidados prestados, um maior desenvolvimento profissional e a melhoria da satisfação dos grupos e comunidades onde decorreram as intervenções. Nele se demonstram as competências desenvolvidas e que convergem nos objetivos académicos definidos por este Mestrado, bem como no perfil de competências preconizado pela Ordem dos Enfermeiros para o desempenho autónomo de cuidados especializados de Enfermagem a grupos e comunidades. O módulo de estágio consistiu no desenvolvimento de um Projeto de Intervenção Comunitária, baseado na metodologia do Planeamento em Saúde, com o objetivo geral de Promover a capacitação e o empoderamento dos adolescentes da E.S.S.L. no âmbito de uma sexualidade saudável e responsável. Na intervenção em enfermagem avançada na comunidade e dando resposta aos problemas/necessidades identificados, foram realizadas sessões de Educação para a Saúde como estratégia de promoção e proteção da saúde e de prevenção da doença, com a finalidade de se atingir o grau de excelência na qualidade de vida e obter ganhos em saúde. A Educação para a Saúde numa ação essencialmente voltada para a Promoção da Saúde desempenha um papel fundamental na capacitação dos indivíduos para a aquisição de hábitos de vida saudáveis e consequentemente na obtenção de ganhos em saúde. A possibilidade de ocorrerem transformações sobre as condições de vida e de saúde nas comunidades depende do acesso a determinadas formas de conhecimento, e a Educação para a Saúde tem um papel significativo face à melhoria das condições de vida e de saúde das populações. Após a intervenção, e ainda que não seja possível avaliar o impacto deste projeto, podemos constatar que as metas estabelecidas foram todas superadas e até ultrapassadas, assim como os objetivos que tinham sido delineados. Observa-se um grau de satisfação em geral com as sessões de Educação para a Saúde desenvolvidas de 98,1%. Esperamos que com a nossa intervenção, as competências pessoais e sociais adquiridas possam ser desenvolvidas e utilizadas para melhorar a vivência da Sexualidade na Adolescência. No entanto, temos consciência de que a intervenção na área da promoção e prevenção, deve ser um trabalho contínuo e dinâmico para se conseguir ganhos em saúde, com resultados a médio/longo prazo

A PHENOMENOLOGY OF MIMETIC LEARNING AND MULTIMODAL COGNITION: INTEGRATING EXPERIENTIAL KNOWLEDGE INTO PROGRAMS IN RHETORIC, COMPOSITION, AND TECHNICAL COMMUNICATION

My dissertation emphasizes a cognitive account of multimodality that explicitly integrates experiential knowledge work into the rhetorical pedagogy that informs so many composition and technical communication programs. In these disciplines, multimodality is widely conceived in terms of what Gunther Kress calls “socialsemiotic” modes of communication shaped primarily by culture. In the cognitive and neurolinguistic theories of Vittorio Gallese and George Lakoff, however, multimodality is described as a key characteristic of our bodies’ sensory-motor systems which link perception to action and action to meaning, grounding all communicative acts in knowledge shaped through body-engaged experience. I argue that this “situated” account of cognition – which closely approximates Maurice Merleau-Ponty’s phenomenology of perception, a major framework for my study – has pedagogical precedence in the mimetic pedagogy that informed ancient Sophistic rhetorical training, and I reveal that training’s multimodal dimensions through a phenomenological exegesis of the concept mimesis. Plato’s denigration of the mimetic tradition and his elevation of conceptual contemplation through reason, out of which developed the classic Cartesian separation of mind from body, resulted in a general degradation of experiential knowledge in Western education. But with the recent introduction into college classrooms of digital technologies and multimedia communication tools, renewed emphasis is being placed on the “hands-on” nature of inventive and productive praxis, necessitating a revision of methods of instruction and assessment that have traditionally privileged the acquisition of conceptual over experiential knowledge. The model of multimodality I construct from Merleau-Ponty’s phenomenology, ancient Sophistic rhetorical pedagogy, and current neuroscientific accounts of situated cognition insists on recognizing the significant role knowledges we acquire experientially play in our reading and writing, speaking and listening, discerning and designing practices.

An investigation of two real time machine learning techniques that could enhance the adaptability of game AI agents

Developers strive to create innovative Artificial Intelligence (AI) behaviour in their games as a key selling point. Machine Learning is an area of AI that looks at how applications and agents can be programmed to learn their own behaviour without the need to manually design and implement each aspect of it. Machine learning methods have been utilised infrequently within games and are usually trained to learn offline before the game is released to the players. In order to investigate new ways AI could be applied innovatively to games it is wise to explore how machine learning methods could be utilised in real-time as the game is played, so as to allow AI agents to learn directly from the player or their environment. Two machine learning methods were implemented into a simple 2D Fighter test game to allow the agents to fully showcase their learned behaviour as the game is played. The methods chosen were: Q-Learning and an NGram based system. It was found that N-Grams and QLearning could significantly benefit game developers as they facilitate fast, realistic learning at run-time.

Modelling the generation of customised poetry in Jess

The present paper presents an application that composes formal poetry in Spanish in a semiautomatic interactive fashion. JASPER is a forward reasoning rule-based system that obtains from the user an intended message, the desired metric, a choice of vocabulary, and a corpus of verses; and, by intelligent adaptation of selected examples from this corpus using the given words, carries out a prose-to-poetry translation of the given message. In the composition process, JASPER combines natural language generation and a set of construction heuristics obtained from formal literature on Spanish poetry.

L'Intégration d'un Module d'Étude Internet Dans la Classe de Comptabilité: Perceptions des Élèves et les Résultats Académiques

Implemented in the context of Business Administration students enrolled in a college level three year technology program, this research investigated students’ perceptions and academic results concurrent with the implementation of an online web module designed to facilitate student self-study. The students involved in this research were enrolled in a program that, while offering a broad education in business disciplines, specialized in the field of accounting. As a result, students were enrolled in academically rigorous accounting courses in each of the six semesters of the program. The weighting of these accounting courses imposes a significant self-study component – typically matching or exceeding the time spent in class. In this context many of the students enrolled in the Business Administration Program have faced difficulties completing the self-study component of the course effectively as demonstrated in low homework completion rates, low homework grade averages and ultimately low success rates in the courses. In an attempt to address this situation this research studied the implementation of a web-based self-study module. Through this module students could access a number of learning tools that were designed to facilitate the self-study process under the premise that more effective self-study learning tools will help remove obstacles and provide more timely confirmation of learning during student self-study efforts. This research collected data from a single cohort of students drawn from the first three sequential accounting courses of the Business Administration Program. The web-based self-study module was implemented in the third of the three sequential accounting courses. The first two of these courses implemented a traditional manual self-study environment. Data collected from the three accounting courses included homework completion rates, homework, exam and final grades for the respective courses. In addition the web-study module allowed the automatic reporting of student usage of a number of specific online learning tools. To complement the academic data, students were surveyed to gain insight into their perceptions of the effectiveness of the web-based system. The research provided a number of interesting insights. First among these was a confirmation of the importance of the self-study process in the academic achievement of the learners. Regardless of the self-study environment, manual or web-enhanced, a significant positive correlation existed between the students’ self-study results, demonstrated in both homework completion rates and homework averages and the corresponding final grades. These results confirm the importance of self-study found generally in the prevailing academic literature regarding students enrolled in higher education. In addition, the web-enhanced learning environment implemented during the third accounting course coincided with significantly higher homework completion rates and corresponding homework averages: homework completion rates in particular increased from a combined average of 63% in the first two accounting courses to 93% in the web-enhanced context of the third accounting course. Moreover, the homework completion rates of the web-enhanced course were evenly distributed across the cohort of students. A quartile-based analysis was subsequently completed. Quartiles were constructed by ranking the students according to their combined average homework completion rates from the first two manual self-study courses, Accounting I and II. The quartile-based homework completion rates for the manual self-study courses Accounting I and II were subsequently compared to the results these same quartiles of students achieved in the web-based self-study within Accounting III. While the first two courses demonstrated significantly uneven homework completion rates across the quartiles ranging from 31% to 91% homework completion rates, the differences among the four quartiles within the web-enhanced module, with an average homework completion rate of 93%, were statistically insignificant. Congruent with the positive academic results observed in the third, web-enhanced course, through the corresponding survey, students expressed a strong attitude in favor of the online self-study environment. This research was designed to add to the existing research that studies the implementation of learning in an online setting. Specifically, the research was designed to explore a middle ground of online learning – a web-enhanced course – a context that supplements the classroom experience rather than replacing it. The web-enhanced accounting course demonstrated impressive favorable results, both academically and in terms of students' perception of the system; these results suggest that a web-enhanced environment can provide learning tools that facilitate the self-study process while providing a structured learning environment that can help developing learners reach their potential.

Film policy in practice: a case study of Scottish Screen’s funding schemes

This thesis examines cultural policy for film in Scotland, from 1997 to 2010. It explores the extent to which the industry is shaped by film policy strategies and through the agency of public funding bodies. It reflects on how Scottish Screen, Scotland’s former screen agency, articulated its role as a national institution concerned with both commercial and cultural remits, with the conflicting interests of different industry groups. The study examines how the agency developed funding schemes to fulfil policy directives during a tumultuous period in Scottish cultural policy history, following the establishment of the Scottish Parliament with the Scotland Act 1998 and preceding the Independence Referendum Act 2013. In order to investigate how policy has shaped the development of a national film industry, a further two case studies are explored. These are Tartan Shorts, Scotland’s former flagship short film scheme, and the Audience Development Fund, Scotland’s first project based film exhibition scheme. The first study explores the planning, implementation and evaluation of the scheme as part of the agency’s talent development strategy. The outcomes of this study show the potential impact of funding methods aimed at developing and retaining Scottish filmmaking talent. Thereafter, the Scottish exhibition sector is discussed; a formerly unexplored field within film policy discussions and academic debate. It outlines Scottish Screen’s legacy to current film exhibition funding practices and the practical mechanisms the agency utilised to foster Scottish audiences. By mapping the historical and political terrain, the research analyses the specificity of Scotland within the UK context and explores areas in which short-term, context-driven policies become problematic. The work concludes by presenting the advantages and issues caused by film funding practices, advocating what is needed for the film industry in Scotland today with suggestions for long-term and cohesive policy development.

Methods of earth building in the Huila Province, Angola

In Angola, the construction made of raw earth is a cultural heritage widely used by low income households, representing over 80% of the population [1, 3]. In Huila province is evident construction in raw earth in a large scale, either in urban or in periurban and rural areas. The construction methods follow the ancestral standards, distributed throughout the region of Huila, being built by the several ethnic groups. Among the construction techniques in earth, stand out: the adobe, wattle-and-daub and more recently on CEB (Compressed Earth Block). The type of soil used to make the adobes is mainly silty-clayed sand [1]. The most applied materials are: rods, reeds, wood, grass, straw, soil and stone, almost with the same characteristics [2]. The manufacture of adobe, consists essentially in mixing clay and grass (plant fibers), then put the mixture inside a wooden mold, having a size of 42 cm long and 18 cm high and taking three to four days to dry and be applied in housing construction. The application of these materials makes the construction less expensive because they are collected, transformed and applied by the owner himself of housing without any project, based only on the result of the practice and experience acquired from their ancestors. They are simple constructions, presenting a typology of grouped and isolated single-family housing, ranging between 2 and 3 bedrooms [2]. The construction techniques used in such small housings have positive environmental aspects, both as regards the materials employed, such as the manner in which the constructions are raised, showing special concerns for the quality improvement of them, as regards the resistance, durability and comfort [4].

Competencias en educación: Ideas para el diseño curricular desde la deliberación práctica y crítica, basada en el desarrollo humano y la transformación social

Los sistemas educativos, en América Latina y en el mundo entero, están siendo llamados a dar respuesta a las exigencias de profesionales altamente formados, que respondan a los conocimientos y habilidades emergentes exigidas por los avances científicos y tecnológicos. Ante esas peticiones de la realidad económica y productiva, las competencias se han convertido en el estandarte para que los sistemas educativos planteen sus propuestas curriculares. En estas se manifiesta la ampliación de los contenidos al aprender funciones o tareas con base en adaptaciones de otros contextos, desde la experticia y sin estudios profundos de la realidad de las fuentes curriculares. En este artículo se plantea la importancia de considerar que un proyecto educativo basado en competencias profesionales se debe visualizar como un proceso de formación de la persona, de manera integral. En el análisis de esa proposición se discute el abordaje de las competencias desde la educación, el cual ha pretendido relacionar la teoría y la práctica, acercando los contenidos académicos al hacer en un puesto de trabajo, en divergencia con la necesidad de razonar las competencias en educación como el medio para integrar el conocimiento y la experiencia. No se trata solo de resolver tareas específicas en un futuro puesto de trabajo, sino también de la búsqueda de soluciones de los problemas en los diferentes ámbitos de la vida. Para el logro de esa visión integradora de la educación, se proponen algunas ideas para diseñar proyectos curriculares por competencias desde la tradición práctica deliberativa y crítica, con una concepción curricular humanista y de transformación social.

Salud sexual, SALUD REPRODUCTIVA Y ABORTO: ¿QUÉ DERECHOS?

ResumenEl aborto es un tema debatido desde hace décadas. En España, se ha aprobado recientemente la LO 2/2010, de salud sexual y reproductiva y de la interrupción voluntaria del embarazo, que implica un importante cambio en la regulación del aborto: establece un sistema de aborto a petición de la embarazada en un plazo, manteniendo determinadas indicaciones durante más tiempo. El presente artículo analiza el contenido de la salud sexual y reproductiva, los derechos de la mujer y la protección del no nacido en el Derecho Internacional, así como la jurisprudencia constitucional española y la diferencia sustancial del sistema de plazos respecto al de supuestos, la ética médica al respecto y las exigencias del consentimiento informado. Finalmente, se aborda el problema del consentimiento de los menores a la unión sexual y al aborto.AbstractAbortion is an issue that has been discussed for decades. In Spain, the Law on sexual and reproductive health and the voluntary interruption of pregnancy (LO 2/2010) has been recently passed. It implies an important change in abortion legislation: it states an abortion upon request of the pregnant woman during a predetermined period of time, while maintaining certain regulations for a long time. This article analyzes the content of sexual and reproductive health, women’s rights and the protection of the unborn under International Law, as well as the constitutional Spanish jurisprudence; the essential difference of the term-based system in regards to the assumptions system, medical ethics on this matter and the requirements of the informed consent. Lastly, the article deals with the problem of the minors’ consent to sexual union and abortion.

Adaptive project planning and management based on best practices - COBRA system

Planning a project with proper considerations of all necessary factors and managing a project to ensure its successful implementation will face a lot of challenges. Initial stage in planning a project for bidding a project is costly, time consuming and usually with poor accuracy on cost and effort predictions. On the other hand, detailed information for previous projects may be buried in piles of archived documents which can be increasingly difficult to learn from the previous experiences. Project portfolio has been brought into this field aiming to improve the information sharing and management among different projects. However, the amount of information that could be shared is still limited to generic information. This paper, we report a recently developed software system COBRA to automatically generate a project plan with effort estimation of time and cost based on data collected from previous completed projects. To maximise the data sharing and management among different projects, we proposed a method of using product based planning from PRINCE2 methodology. (Automated Project Information Sharing and Management System -�COBRA) Keywords: project management, product based planning, best practice, PRINCE2

An entropy-based financial decision support system (e-FDSS) for project analysis in construction SMEs

Uncertainty contributes a major part in the accuracy of a decision-making process while its inconsistency is always difficult to be solved by existing decision-making tools. Entropy has been proved to be useful to evaluate the inconsistency of uncertainty among different respondents. The study demonstrates an entropy-based financial decision support system called e-FDSS. This integrated system provides decision support to evaluate attributes (funding options and multiple risks) available in projects. Fuzzy logic theory is included in the system to deal with the qualitative aspect of these options and risks. An adaptive genetic algorithm (AGA) is also employed to solve the decision algorithm in the system in order to provide optimal and consistent rates to these attributes. Seven simplified and parallel projects from a Hong Kong construction small and medium enterprise (SME) were assessed to evaluate the system. The result shows that the system calculates risk adjusted discount rates (RADR) of projects in an objective way. These rates discount project cash flow impartially. Inconsistency of uncertainty is also successfully evaluated by the use of the entropy method. Finally, the system identifies the favourable funding options that are managed by a scheme called SME Loan Guarantee Scheme (SGS). Based on these results, resource allocation could then be optimized and the best time to start a new project could also be identified throughout the overall project life cycle.