Retratos de mulheres na literatura brasileira do século XIX

The aim of this article is to broaden our understanding of education and the concept of womanhood in the Brazilian society of the 19th century. On the basis of the analysis of a number of novels typical of the period it is concluded that novels had or intended to have a pedagogical function among the educated elite in the education of women. In this way, literature constituted an expression of a dominant and socially determined conception of womanhood and a pedagogical instrument that imposed social values.

A crise na sociedade do trabalho e sua importância na contextualização dos conteúdos curriculares do ensino médio

This article has as objective to discuss some topics concerning the supposed crisis of the society of the work and its consequences for the debate in social sciences and also for the work category contextualization in the secondary school curriculum. As the work has represented an important explanation category for the classic social thought, the contemporary paradigm of deep metamorphoses in the world of the work and the advent of the new question (CASTELS, 1995; ROSANVALLON, 1995) backward the necessity to rethink the theoretical shades that base the interpretation of the social life on the current context, when the center position of the work is being questioned. Having taken some theoretical references from the sociology of the work, we search to delineate on a brief way the quarrel about the dimensions of the social and political phenomena these days and the importance of this debate on the contextualization of the secondary school curriculum contents.

Educational and professional background and success in the labor market: the case of Portuguese immigrants in the Netherlands

The aim of this paper is to describe the relationship between educational and professional occupation trajectories of Portuguese immigrants in The Netherlands. To this end, the sample used comprises Portuguese immigrants that arrived in The Netherlands in two periods which represent the highest influx of immigrants: around the years 1966 and 2002. The analysis of the data shows a strong relationship between the level of professional education and the level of professional occupation. Furthermore, some exceptions to the generalizations found show that in service training may lead to an improvement of the possibilities to ascend regarding the level of professional occupation.

A Faculdade de Filosofia, Ciências e Letras de São José do Rio Preto no período de 1957 a 1964: estudo de uma instituição escolar

According to the existing literature, the FFCL of São José do Rio Preto had a pioneering role as regards the organization and management of higher education. This article aims to discuss the originality/innovativeness of the educational project of this institution in the period from 1957 to 1964, based on an analysis of departmental organization and student participation. In order to do so, we use documents about the creation process of the FFCL, reports of courses, and minutes of departmental meetings and of the Academic Philosophical Center. The results show that, indeed, this institution was organized in three departments, though these operated in consonance with the chair system. Student participation varied from equal representation to the representation of a single student per class. Thus, the results show that the innovative/revolutionary character of this institution was exaggerated in the existing literature and may have contributed to the existing “mysticism” in the city as regards the history and the importance of this institution.

Key participants of the tumor microenvironment of the prostate: An approach of the structural dynamic of cellular elements and extracellular matrix components during epithelial-stromal transition

Cancer is a multistep process that begins with the transformation of normal epithelial cells and continues with tumor growth, stromal invasion and metastasis. The remodeling of the peritumoral environment is decisive for the onset of tumor invasiveness. This event is dependent on epithelial–stromal interactions, degradation of extracellular matrix components and reorganization of fibrillar components. Our research group has studied in a new proposed rodent model the participation of cellular and molecular components in the prostate microenvironment that contributes to cancer progression. Our group adopted the gerbil Meriones unguiculatus as an alternative experimental model for prostate cancer study. This model has presented significant responses to hormonal treatments and to development of spontaneous and induced neoplasias. The data obtained indicate reorganization of type I collagen fibers and reticular fibers, synthesis of new components such as tenascin and proteoglycans, degradation of basement membrane components and elastic fibers and increased expression of metalloproteinases. Fibroblasts that border the region, apparently participate in the stromal reaction. The roles of each of these events, as well as some signaling molecules, participants of neoplastic progression and factors that promote genetic reprogramming during epithelial–stromal transition are also discussed.

Novel inorganic pyrophosphatase from soil metagenomic and family and subfamily prediction

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

MetaPPase by in silico analyses predicting the novel gene operate as H+ pumps.

The lastyears declined the discovery of compounds to use in industrial and naturaldiversity has been the best supplier for novel genes, enzymes and compounds inhigh demand by the biotechnology industry. We know immense diversity of microorganisms,yet most remains unexplored. For these reason we use the metagenômica approach toinvestigate the potential of uncultured microorganisms. With this purpose weused the metagenomic library of from Eucalyptus spp. arboretum (EAA), wedid screening to found positive clone and them was submitted to the process of shotgun,the data obtained was submitted a bioinformatics analyses. Our results showsthe hypothesis of high unexplored microbial diversity of soil are able to foundnovel genes and metagenomic approach is and allowed to isolate novel genes and insilico analyses are essential part to identify a novel Inorganicpyrophosphatase (PPase) prediction indicated the novel gene operate as H+ pumps. Thissuggests that a special feature, our work in situ will be cloning thegene expression vector for subsequent kinetic characterization and crystallization.

Ecos do surrealismo e o grupo OULIPO

This article aims to trace a brief panorama of the Oulipo group, founded in France in the sixties and still in existence. This group became known by the rules imposed on its members for the creation of any literary text and also, for fl irting with mathematics. The purpose of this study is to enumerate some of the many constraints created by the group and connect some procedures to the surrealist movement.

O despreparo de professores diante da educação sexual e diversidade sexual na escola

Este trabalho sustenta-se em uma compreensão de que a Educação Escolar e a Educação Sexual são processos que ocorrem na relação com o contexto social e histórico. No campo da sexualidade, o contexto social determina padrões de normalidade baseados na ideia de heteronormatividade compulsória, o que discrimina a diversidade sexual. Esta questão é ilustrada com dados de pesquisa que demonstram o relato de professores de escolas públicas sobre a homossexualidade evidenciando a falta de conhecimento sobre o assunto, o preconceito e as dificuldades em tratar o tema na escola. Ressalta-se, portanto, a importância da inserção do tema sexualidade na formação inicial e continuada dos professores.

Doença periodontal em pacientes com Diabetes Mellitus: influência de polimorfismos genéticos?

Currently it is clear that there are several factors that can act as modifiers of diseases, without causing them directly, but having the potential to make these conditions to progress faster and more severe. There is a growing number of studies investigating the relationship between Diabetes Mellitus (DM) and Periodontal Disease (PD), including some studies focusing on the influence of genetic factors in this process. The aim of this study was to verify through a literature review, the influence of genetic polymorphisms in the development of PD in patients with DM. PubMed and BIREME were used as databases and the terms Periodontitis or Periodontal Disease, Polymorphism, Diabetes Mellitus were searched. After a refinement in the literature, five studies were selected and they were related to chronic PD with DM and polymorphisms in cytokine genes, especially interleukin 1 (IL1) e IL6. Polymorphisms were associated with a higher concentration of pro-inflammatory cytokines in the gingival crevicular fluid of diabetic patients when compared to non-diabetic. In conclusion, it is necessary to confirm this association with longitudinal studies that must investigate a larger number of cytokine genes in order to understand the cause-effect relationship between genetic polymorphisms, DM and PD.

Modulation of Immune Response by RAGE and TLR4 Signalling in PBMCs of Diabetic and Non-Diabetic Patients

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Implantes dentais em pacientes com diabetes mellitus

Dental implants represent a great improvement in Dentistry in respect to rehabilitation of edentulous ridges due to the functional and aesthetic reestablishment with long-term predictability and success. However, the effectiveness of this treatment relies on successful osseointegration during the healing period. In this way, the applicability of dental implants in patients with diabetes mellitus (DM) remains controversial, by the fact that the hyperglycemic status presents a negative effect on the osseointegration. It is not clear yet if the therapy with dental implants is an absolute contraindication to these patients. For this reason, the aim of the present study is to review the literature about the treatment with dental implants in patients with diabetes and to propose a protocol to perform dental implants in patients with diabetes. Diabetes has been considered a relative contraindication to dental implants, as the patients with adequate metabolic control can be treated with this kind of therapy, because inadequate metabolic control can lead to the failure of the treatment. Besides, there are risk factors for the diabetic implant patient that may decrease the success rates of dental implants therapy. In this way, the dentist should understand all the relevant implications before considering the indication of dental implants to patients with diabetes. It is important to have more controlled studies to evaluate the effects of diabetes on the implant-tissue interface and further investigations are necessary in order to elucidate the role of insulin and molecular mechanisms that might interfere on the osseointegration in patients with diabetes.

The influence of different implant surfaces on osseointegration in diabetes: a systematic review of the literature

AIM: The aim of this study was to evaluate, through a systematic review of the literature, the effects of different implant surface modifications on osseointegration in diabetic subjects. METHODS: A search was performed of the PubMed database, using a combination of the following keywords: “Implant surface” OR “Dental implants” AND “Diabetes” OR “Hyperglycemia”. Papers published in English between January 1960 and November 2013 were selected. All experimental models were considered in this search, but case reports and in vitro studies were excluded from this review. RESULTS: The initial search identified 182 articles. After reading the titles and abstracts, 39 articles were selected for full reading. Finally, 4 papers were selected after evaluation of all the papers, and these papers are discussed in this review. Due to the methodological heterogeneity of the selected studies, it was not possible to perform a meta-analysis of the data. CONCLUSION: It can be concluded that although the benefits of surface modifications present in individuals with diabetes have biological plausibility, there is little evidence of the benefits of these modifications.